期刊
EUROPEAN JOURNAL OF IMMUNOLOGY
卷 38, 期 4, 页码 934-937出版社
WILEY
DOI: 10.1002/eji.200738107
关键词
Regulatory T cell; Rheumatoid arthritis; Therapy
类别
资金
- Versus Arthritis [17707] Funding Source: researchfish
- Arthritis Research UK [17707] Funding Source: Medline
- Versus Arthritis [17707] Funding Source: Medline
Treg play a vital role in the maintenance of tolerance to self antigens, thereby preventing disease through the active suppression of proliferation and pro-inflammatory cytokine production by autoreactive T cells. Here we discuss strategies aimed at enhancing Treg function in patients with rheumatoid arthritis with the ultimate aim of restoring lasting tolerance but without increasing the risk of infections or cancer.
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