Article
Cardiac & Cardiovascular Systems
Yao Wang, Haojie Zhu, Xiaofeng Hou, Zhao Wang, Fengwei Zou, Zhiyong Qian, Yongyue Wei, Xiang Wang, Longyao Zhang, Xiaofei Li, Zhimin Liu, Siyuan Xue, Chaotong Qin, Jiaxin Zeng, Hui Li, Hongping Wu, Hong Ma, Kenneth A. Ellenbogen, Michael R. Gold, Xiaohan Fan, Jiangang Zou
Summary: Left bundle branch pacing (LBBP) shows greater improvement in left ventricular ejection fraction (LVEF) compared to biventricular pacing (BiVP) in heart failure patients with nonischemic cardiomyopathy and left bundle branch block (LBBB).
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2022)
Article
Medicine, General & Internal
Agata Tyminska, Krzysztof Ozieranski, Emil Brociek, Agnieszka Kaplon-Cieslicka, Pawel Balsam, Michal Marchel, Maria G. Crespo-Leiro, Aldo P. Maggioni, Jaroslaw Drozdz, Grzegorz Opolski, Marcin Grabowski
Summary: Eligibility criteria for cardiac resynchronization therapy (CRT) in heart failure patients have changed over the past fifteen years, leading to underuse of this form of pacing. More studies are needed to improve outcomes and personalize management for heart failure patients.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Cardiac & Cardiovascular Systems
Ying Gu, Yanming Li, Ying Zhu, Xiuyu Lin, Tian Tian, Qigao Zhang, Jianbin Gong, Lei Wang, Jianhua Li
Summary: The study concludes that left bundle branch pacing (LBBP) is a feasible and effective treatment for heart failure patients with left ventricular ejection fraction (LVEF) <50% and left bundle branch block (LBBB). LBBP improves left ventricular structure and function with a low and stable pacing threshold.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2022)
Article
Cardiac & Cardiovascular Systems
Xueying Chen, Yang Ye, Zhongkai Wang, Qinchun Jin, Zhaohui Qiu, Jingfeng Wang, Shengmei Qin, Jin Bai, Wei Wang, Yixiu Liang, Haiyan Chen, Xia Sheng, Feng Gao, Xianxian Zhao, Guosheng Fu, Kenneth A. Ellenbogen, Yangang Su, Junbo Ge
Summary: This study evaluated the feasibility and efficacy of left bundle branch pacing (LBBP-CRT) compared to optimized biventricular pacing (BVP-aCRT) in HFrEF patients with LBBB. The results showed that LBBP-CRT achieved better electromechanical resynchronization and higher clinical and echocardiographic response.
Article
Cardiac & Cardiovascular Systems
Xiang-Fei Feng, Ling-Chao Yang, Yan Zhao, Yi-Chi Yu, Bo Liu, Yi-Gang Li
Summary: The study demonstrates that LOT-aCRT is clinically feasible in patients with systolic heart failure and LBBB. LOT-aCRT was associated with significant narrowing of the QRSd and improvement in LV function.
BMC CARDIOVASCULAR DISORDERS
(2022)
Article
Physiology
Marina Strocchi, Karli Gillette, Aurel Neic, Mark K. Elliott, Nadeev Wijesuriya, Vishal Mehta, Edward J. Vigmond, Gernot Plank, Christopher A. Rinaldi, Steven A. Niederer
Summary: This study compared the electrical synchrony of conventional CRT, HBP, and LBP in RBBB patients and found that HBP significantly improved activation times for RBBB patients, while CRT and LBP were ineffective. Furthermore, the response to LBP improved when LBP was combined with anodal capture of the RV septum myocardium.
FRONTIERS IN PHYSIOLOGY
(2022)
Article
Cardiac & Cardiovascular Systems
Kamil Sedlacek, Helena Jansova, Vlastimil Vancura, Domenico Grieco, Josef Kautzner, Dan Wichterle
Summary: The study included 133 consecutive patients, and found that delta CRT correlated with native QRSd, ECG-based cLBBB, Q-LV, and delta RVP, with delta RVP showing the strongest predictive value.
Article
Cardiac & Cardiovascular Systems
Daniel J. Friedman, Sana M. Al-Khatib, Frederik Dalgaard, Marat Fudim, William T. Abraham, John G. F. Cleland, Anne B. Curtis, Michael R. Gold, Valentina Kutyifa, Cecilia Linde, Anthony S. Tang, Fatima Ali-Ahmed, Antonio Olivas-Martinez, Lurdes Y. T. Inoue, Gillian D. Sanders
Summary: Benefit from cardiac resynchronization therapy (CRT) varies by QRS characteristics, with LBBB and IVCD patients having better outcomes than RBBB patients. CRT is associated with reduced risk of heart failure hospitalization or death in patients with QRS >= 150 ms and LBBB or IVCD, but not for those with RBBB.
Article
Cardiac & Cardiovascular Systems
Zhixin Jiang, Tian Wu, Yixian Wu, Zenghong Chen, Wen Yang, Chongchong Chen, Xiujuan Zhou, Qijun Shan
Summary: The present study compared the effects of left bundle branch area pacing (LBBAP) on cardiac function and clinical outcomes in patients with left bundle branch block (LBBB) and left ventricular ejection fraction (LVEF) > 35% vs. <= 35%. The results showed that LBBAP can significantly shorten QRS duration and improve cardiac function in both groups.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2022)
Review
Cardiac & Cardiovascular Systems
Bengt Herweg, Allan Welter-Frost, Pugazhendhi Vijayaraman
Summary: Cardiac resynchronization therapy (CRT) is the only known non-pharmacologic heart failure therapy that improves cardiac function, functional capacity, and survival while decreasing cardiac workload and hospitalization rates. However, limitations of conventional CRT include difficulties with myocardial scar, fibrosis, and inability to effectively simulate diseased tissue. Studies have shown that endocardial stimulation is more effective than epicardial stimulation in closer proximity to the specialized conduction system.
Article
Cardiac & Cardiovascular Systems
Wen Liu, Chunqiang Hu, Yanan Wang, Yufei Cheng, Yingjie Zhao, Yang Liu, Shaoxin Zheng, Haiyan Chen, Xianhong Shu
Summary: LBBAP effectively improves cardiac function, mechanical synchronization, and mechanical efficiency in heart failure patients, suggesting it as a promising alternative for cardiac resynchronization therapy compared to traditional BVP.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2021)
Review
Physiology
Nathan W. Kong, Gaurav A. Upadhyay
Summary: Cardiac resynchronization therapy (CRT) via biventricular pacing (BiVP) is an established treatment for patients with left ventricular systolic heart failure and intraventricular conduction delay resulting in wide QRS. However, recent studies have shown that there may be different underlying pathophysiology for patients with left bundle branch block (LBBB), suggesting that alternative treatment approaches may be more suitable for these patients.
FRONTIERS IN PHYSIOLOGY
(2022)
Article
Cardiac & Cardiovascular Systems
Lan Su, Songjie Wang, Shengjie Wu, Lei Xu, Zhouqing Huang, Xiao Chen, Rujie Zheng, Limeng Jiang, Kenneth A. Ellenbogen, Zachary Whinnett, Weijian Huang
Summary: Left bundle branch pacing (LBBP) showed high success rates and low complication rates in a large population of patients, leading to decreased QRS duration, improved left ventricular function, and reduced severity of tricuspid regurgitation.
CIRCULATION-ARRHYTHMIA AND ELECTROPHYSIOLOGY
(2021)
Article
Cardiac & Cardiovascular Systems
Hsin-Ti Huang, Jin-Long Huang, Po-Lin Lin, Ying-Hsiang Lee, Chien-Yi Hsu, Fa-Po Chung, Chia-Te Liao, Wei-Ru Chiou, Wen-Yu Lin, Huai-Wen Liang, Hung-Yu Chang
Summary: This study evaluates the clinical impacts of SAC/VAL on reverse cardiac remodeling in HFrEF patients with different QRS durations, and finds that shorter QRS durations are associated with more significant left ventricular improvement after SAC/VAL treatment. Further investigation is needed for optimal intervention timing in CRT-eligible patients.
Article
Cardiac & Cardiovascular Systems
Yixiu Liang, Jingfeng Wang, Xue Gong, Hongyang Lu, Ziqing Yu, Lei Zhang, Minghui Li, Lei Pan, Xueying Chen, Jie Cui, Weiwei Zhang, Ruogu Li, Xiaohong Zhou, Weijian Huang, Yangang Su, Junbo Ge
Summary: The study compared the acute improvement of left bundle branch pacing (LBBP) and biventricular pacing (BVP) in patients with heart failure. The results showed that LBBP provided greater improvements in electrical and mechanical synchrony, as well as hemodynamics, compared to BVP.
CIRCULATION-ARRHYTHMIA AND ELECTROPHYSIOLOGY
(2022)
Editorial Material
Cardiac & Cardiovascular Systems
J. Schroemges, F. A. L. E. Bracke, B. M. van Gelder
NETHERLANDS HEART JOURNAL
(2018)
Article
Computer Science, Software Engineering
Dennis Dingen, Marcel van't Veer, Patrick Houthuizen, Eveline H. J. Mestrom, Erik H. H. M. Korsten, Arthur R. A. Bouwman, Jarke van Wijk
IEEE TRANSACTIONS ON VISUALIZATION AND COMPUTER GRAPHICS
(2019)
Editorial Material
Cardiac & Cardiovascular Systems
Peter P. T. de Jaegere, Patrick Houthuizen, Frits W. Prinzen
JACC-CARDIOVASCULAR INTERVENTIONS
(2019)
Article
Biotechnology & Applied Microbiology
Fenna C. P. Poulussen, Bas J. Peters, Ken Ho Hua, Patrick Houthuizen, Rene J. Grouls, Maarten J. Deenen
PHARMACOGENETICS AND GENOMICS
(2019)
Article
Acoustics
Louis S. Fixsen, Anouk G. W. de Lepper, Marc Strik, Lars B. van Middendorp, Frits W. Prinzen, Frans N. van de Vosse, Patrick Houthuizen, Richard G. P. Lopata
ULTRASOUND IN MEDICINE AND BIOLOGY
(2019)
Article
Cardiac & Cardiovascular Systems
Frank Bracke, Niels Verberkmoes, Marcel van't Veer, Berry van Gelder
Article
Cardiac & Cardiovascular Systems
Ruud F. Spee, Victor M. Niemeijer, Thijs Schoots, Anton Tuinenburg, Patrick Houthuizen, Pieter F. Wijn, Pieter A. Doevendans, Hareld M. Kemps
INTERNATIONAL JOURNAL OF CARDIOLOGY
(2020)
Article
Cardiac & Cardiovascular Systems
Suneet Mittal, Bruce L. Wilkoff, Charles Kennergren, Jeanne E. Poole, Ralph Corey, Frank A. Bracke, Antonio Curnis, Kamel Addo, Joaquin Martinez-Arraras, Ziad F. Issa, Calum Redpath, Jean Moubarak, Surinder Kaur Khelae, Lucas V. A. Boersma, Panagiotis Korantzopoulos, Jo Krueger, Jeff D. Lande, Gina M. Morss, Swathi Seshadri, Khaldoun G. Tarakji
Article
Cardiac & Cardiovascular Systems
Jules R. Olsthoorn, Niels J. Verberkmoes, Michiel W. Pieraets, Patrick Houthuizen, Albert H. M. van Straten
JOURNAL OF CARDIAC SURGERY
(2020)
Article
Medicine, General & Internal
Reinoud E. Knops, Louise R. A. Olde Nordkamp, Peter-Paul H. M. Delnoy, Lucas V. A. Boersma, Juergen Kuschyk, Mikhael F. El-Chami, Hendrik Bonnemeier, Elijah R. Behr, Tom F. Brouwer, Stefan Kaab, Suneet Mittal, Anne-Floor B. E. Quast, Lonneke Smeding, Willeke van der Stuijt, Anouk de Weger, Koen C. de Wilde, Nick R. Bijsterveld, Sergio Richter, Marc A. Brouwer, Joris R. de Groot, Kirsten M. Kooiman, Pier D. Lambiase, Petr Neuzil, Kevin Vernooy, Marco Alings, Tim R. Betts, Frank A. L. E. Bracke, Martin C. Burke, Jonas S. S. G. de Jong, David J. Wright, Jan G. P. Tijssen, Arthur A. M. Wilde
NEW ENGLAND JOURNAL OF MEDICINE
(2020)
Article
Cardiac & Cardiovascular Systems
F. A. Bracke, N. Rademakers, N. Verberkmoes, M. Van 't Veer, B. M. van Gelder
Summary: Efficiency and safety are key factors in choosing lead extraction tools, and our study compared different endovascular techniques for extracting pacing and defibrillator leads. Results showed that all three techniques were equally effective in completely removing the leads, but the laser sheath had significantly more major complications compared to the femoral approach or rotating mechanical sheaths. No single endovascular technique was sufficient to successfully extract all leads.
NETHERLANDS HEART JOURNAL
(2022)
Editorial Material
Cardiac & Cardiovascular Systems
Frank A. A. Bracke, Leonard M. M. Rademakers, Dennis van Veghel
Summary: The introduction of dedicated tools for pacing and defibrillator lead extraction has led to high success rates and low complications. However, not extracting redundant leads minimizes risks and avoids unnecessary expensive procedures for patients.
NETHERLANDS HEART JOURNAL
(2023)
Meeting Abstract
Cardiac & Cardiovascular Systems
F. Bracke, N. Verberkmoes, N. Rademakers, M. Van't Veer, B. M. Van Gelder
EUROPEAN HEART JOURNAL
(2020)
Article
Radiology, Nuclear Medicine & Medical Imaging
Sjoerd Bouwmeester, Marloes de Kleijn, Jan van Wijngaarden, Patrick Houthuizen
JOURNAL OF ULTRASONOGRAPHY
(2019)
Review
Endocrinology & Metabolism
B. Lascaris, S. Pouwels, P. Houthuizen, L. R. Dekker, S. W. Nienhuijs, R. A. Bouwman, M. P. Buise