Article
Polymer Science
Qingwen Yu, Zhiyuan Meng, Yichao Liu, Zehao Li, Xing Sun, Zheng Zhao
Summary: In this study, a curcumin-loaded chitosan nanoparticles encapsulated silk fibroin/hyaluronic acid esterified by methacrylate hydrogel was developed for osteosarcoma therapy and bone regeneration. The hydrogel exhibited superior physical properties and dual functionality, inhibiting tumor growth while promoting osteoblast proliferation.
Article
Multidisciplinary Sciences
Gemma Egan, Suttinee Phuagkhaopong, Saphia A. L. Matthew, Patricia Connolly, F. Philipp Seib
Summary: Silk is a versatile material with various medical applications, including wound care. The dissolved silk fibroin in hydrogels is found to be responsible for their therapeutic response in wound healing. By manipulating the structure of silk fibroin, the biological response of hydrogels can be influenced.
SCIENTIFIC REPORTS
(2022)
Article
Chemistry, Multidisciplinary
N. Jaya Prakash, D. Shanmugarajan, B. Kandasubramanian, P. Khot, K. Kodam
Summary: The production of biodegradable dressing capable of sustained drug release, along with the monitoring of wound conditions, represents new heights of multifunctional platforms for wound care. The reported curcumin-loaded silk fibroin has shown sustained drug release over the time of 10 days through a non-Fickian diffusion process satisfying Korsmeyer-Peppas' model along with the visual monitoring of wound healing through notable color variation with pH as a biomarker. The superhydrophobic nature (water contact angle = 163.7) of the SF, along with the lipophilicity (CA = 0 (Blood)) and hygroscopic nature prevents wetting of wound surface, whereas the excess exudates from wounds are absorbed along with sufficient water and oxygen permeability. The pH responsiveness as a result of the keto-enol tautom-erism in curcumin was utilized for wound monitoring through visual indication enabling even ordinary people to detect the state of the wound. The in-situ biodegradation studies verified using cow-dung slurry, the degradability of the material with 25.3% weight loss within 30 days following first-order kinetics (R2 = 0.994), as a result of the attack of proteolytic enzymes on the amino acid units of SF, mitigating the concerns of medical wastes. (c) 2022 Elsevier Ltd. All rights reserved.
MATERIALS TODAY CHEMISTRY
(2023)
Article
Biochemistry & Molecular Biology
Yuting Wu, Chan Chen, Weikang Tang, Wenbin Liu
Summary: A facile strategy for in situ synthesis of stable and small silver nanoparticles (AgNPs) using DOPA-containing fibroin is developed. The material exhibits excellent antibacterial properties and can potentially be applied in biological and medical fields to treat bacterial infections.
MACROMOLECULAR BIOSCIENCE
(2023)
Article
Polymer Science
Mohamed Chaala, Fatima Zohra Sebba, Marta G. Fuster, Imane Moulefera, Mercedes G. Montalban, Guzman Carissimi, Gloria Villora
Summary: The development of new biomaterials from natural fibres, especially silk fibroin, has gained significant attention in the field of biomedicine. Hydrogels, which are flexible polymer networks capable of absorbing large amounts of water and accommodating drugs or cells, have emerged as potential candidates for various applications such as scaffolding and cell therapy. In this study, curcumin-hyaluronic acid-silk fibroin hydrogels were prepared using a simple sonication process. The hydrogels were characterized using various techniques and their biological activity was evaluated using fibroblast cell viability assays.
Article
Food Science & Technology
Oguz Bayraktar, Yasemin Yahsi, Merve Deniz Kose
Summary: This study focused on encapsulating trans-resveratrol in core/shell nanoparticles to preserve its stability. Nanoparticles ranging in size from 8.2 to 254 nm were successfully prepared using coaxial electrospraying. The encapsulation process parameters were optimized using Central Composite Design and Response Surface Methodology to achieve high encapsulation yield, efficiency, and small particle size while maintaining thermal and UV stabilities.
FOOD AND BIOPROCESS TECHNOLOGY
(2021)
Article
Polymer Science
Chul Min Yang, Jeehee Lee, Su Yeon Lee, Haeshin Lee, Kiramage Chathuranga, Jongsoo Lee, Wonho Park
Summary: In this study, a modified silk fibroin (SF-BGE) soluble in water was prepared by introducing butyl glycidyl ether (BGE) into its side chain. A coordination bond between ZnO and tannic acid (TA) was formed to develop an SF-based nanocomposite hydrogel. The hydrogel showed superior hemostatic and cytocompatible activities.
Article
Biochemistry & Molecular Biology
Chul Min Yang, Jeehee Lee, Haeshin Lee, Won Ho Park
Summary: Due to the destruction of the ozone layer, increased exposure to UV radiation negatively affects both skin diseases and wound healing. To address the limitations in safety of commercially available sunscreens, researchers developed a highly safe sunscreen using a silk fibroin composite with biocompatibility and blood coagulation activity. By improving the solubility of silk fibroin and incorporating tannic acid and zinc oxide nanoparticles, a multifunctional hydrogel sunscreen was created with UV blocking, hemostatic, antibacterial, and antioxidant effects.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2022)
Article
Chemistry, Multidisciplinary
Ziyang Sun, Haoran Liu, Dandan Dai, Hao Lyu, Ruochuan Huang, Wenzhao Wang, Chengchen Guo
Summary: This study presents a promising injectable cell-laden hydrogel system based on silk acid, which exhibits good cytocompatibility and injectability. The hydrogel has potential applications in 3D cell culture, targeted cell delivery, and tissue engineering.
CHEMICAL COMMUNICATIONS
(2023)
Article
Biotechnology & Applied Microbiology
Giorgio Rizzo, Marco Lo Presti, Cinzia Giannini, Teresa Sibillano, Antonella Milella, Giulia Guidetti, Roberta Musio, Fiorenzo G. Omenetto, Gianluca M. Farinola
Summary: Silk Fibroin (SF) obtained from Bombyx mori can be processed into scaffolds from aqueous solutions using chaotropic salts. By modifying the standard Ajisawa's method with CeCl3, it is possible to regenerate SF as a fibrous material with an ordered structure and doped with Ce+3 ions. Lanthanide ions are found to solubilize SF and favor the reprecipitation of fibrous SF, making them potential candidates for developing new photonic systems.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2021)
Article
Materials Science, Multidisciplinary
Chenxi Zhao, Yawen Liu, Zhuochen Lv, Leitao Cao, Jing Ren, Zhengzhong Shao, Shengjie Ling
Summary: This study developed a silk protein-based nacre with mechanical properties superior to natural nacre by imitating the structure of natural nacre. The silk fibroin nacre can be used for structural engineering and biomedical applications, thanks to its good processability and tunable coloration.
ADVANCED FIBER MATERIALS
(2022)
Article
Polymer Science
Beste Cagdas Tunali, Omer Akturk, Durukan Sahingoz, Mustafa Turk, Ayten Celebi Keskin
Summary: In this study, polyethyleneimine-capped gold nanoparticles (PEI-AuNPs) were synthesized using the pulsed laser ablation in liquid (PLAL) technique, and then combined with Bombyx mori silk fibroin (SF) to form nanocomposites (PEI-SF-AuNPs). The biocompatibility of PEI-AuNPs and PEI-SF-AuNPs in breast cancer cells MCF-7 and MDA-MB231 were tested, and it was found that PEI-AuNP1 showed the least cytotoxicity. Therefore, PEI-AuNP1 nanocomposites can be suggested as siRNA carriers in gene-based breast cancer therapies.
EUROPEAN POLYMER JOURNAL
(2023)
Article
Polymer Science
Zhi-Yuan Meng, Li Wang, Lin-Yi Shen, Ze-Hao Li, Zheng Zhao, Xin-Yu Wang
Summary: In this study, biomimetic sodium alginate (SA)/silk fibroin (SF) scaffolds were fabricated using supercritical CO2 technology, exhibiting nanofibrous structures and interconnected porous properties. The addition of SA microparticles improved tensile and compressive strength, reduced porosity, and regulated degradation rate of the SF scaffolds. The scaffolds showed high biocompatibility, cell adhesion ability, and promote fibroblasts proliferation, making them potentially valuable for skin tissue engineering.
JOURNAL OF APPLIED POLYMER SCIENCE
(2021)
Article
Nanoscience & Nanotechnology
Yu Zhou, Chi Gu, Jizhi Liang, Bohan Zhang, Huiran Yang, Zhitao Zhou, Meng Li, Liuyang Sun, Tiger H. Tao, Xiaoling Wei
Summary: The combination of optogenetics and electrophysiological recording allows for high-precision bidirectional interactions between neural interfaces and neural circuits, offering a promising approach for studying progressive neurophysiological phenomena. In this study, a hybrid probe (Silk-Optrode) composed of a silk protein optical fiber and flexible microelectrode arrays is reported. The Silk-Optrode exhibits accurate implantation into the brain and enables synchronized optogenetic stimulation and multichannel recording in freely behaving animals. By utilizing the hydration of the silk optical fiber, the Silk-Optrode adapts to the environment after implantation and reduces its own mechanical stiffness to ensure high fidelity implantation while maintaining mechanical compliance with the surrounding tissue. The probe with 128 recording channels can detect well-isolated single units and perform intracranial light stimulation with low optical losses, surpassing previous similar work. Results from a two-month post-surgery evaluation suggest that the Silk-Optrode probe exhibits improved implant-neural interfaces with less immune response and tissue damage.
MICROSYSTEMS & NANOENGINEERING
(2022)
Article
Biochemistry & Molecular Biology
Yashi Agarwal, P. S. Rajinikanth, Shivendu Ranjan, Upama Tiwari, J. Balasubramnaiam, Prashant Pandey, Dilip Kumar Arya, Sneha Anand, Payal Deepak
Summary: Electrospinning is a versatile technique for nanofibers fabrication, which is crucial for rapid healing of diabetic wounds. The combination of silk fibroin-curcumin based nanofibers with PCL and PVA strengthens the wound healing properties. The loaded nanofibers demonstrate sustained release of curcumin and show great potential for diabetic wound healing.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2021)
Article
Chemistry, Multidisciplinary
Zeyu Luo, Guosheng Tang, Hossein Ravanbakhsh, Wanlu Li, Mian Wang, Xiao Kuang, Carlos Ezio Garciamendez-Mijares, Liming Lian, Sili Yi, Junlong Liao, Maobin Xie, Jie Guo, Zongke Zhou, Yu Shrike Zhang
Summary: This study presents a technique that utilizes cryoprotective bioink to enable direct extrusion bioprinting in the vertical direction. The unique vertical 3D cryo-bioprinting technique allows the creation of freestanding constructs with anisotropic microchannels, enhancing cell viability and growth. This technique has broad applications in interface tissue engineering and shows potential in tissue engineering, regenerative medicine, drug discovery, and personalized therapeutics.
ADVANCED MATERIALS
(2022)
Article
Engineering, Biomedical
Liming Lian, Cuiping Zhou, Guosheng Tang, Maobin Xie, Zixuan Wang, Zeyu Luo, Julia Japo, Di Wang, Jianhua Zhou, Mian Wang, Wanlu Li, Sushila Maharjan, Marina Ruelas, Jie Guo, Xunwei Wu, Yu Shrike Zhang
Summary: The study introduces a vertical embedded extrusion bioprinting technique that allows precise control of vertical structure characteristics and successfully reconstructs key structures of intestinal villi and hair follicles, partially restoring functionality in vitro.
ADVANCED HEALTHCARE MATERIALS
(2022)
Article
Nanoscience & Nanotechnology
Xuchen Wang, Peixin Liu, Qinting Wu, Zhaozhu Zheng, Maobin Xie, Guoqiang Chen, Jia Yu, Xiaoqin Wang, Gang Li, David Kaplan
Summary: Silk sutures with antibacterial and anti-inflammatory functions were developed for sustained dual-drug delivery to prevent surgical site infections. The silk sutures demonstrated both rapid and sustained release of drugs, inhibiting biofilm formation and promoting wound healing. These sutures exhibited favorable biocompatibility and potential for surgical applications.
ACS APPLIED MATERIALS & INTERFACES
(2022)
Article
Chemistry, Multidisciplinary
Yajun Min, Ruijia Han, Guanlin Li, Xinyu Wang, Shilu Chen, Maobin Xie, Zheng Zhao
Summary: A dual-functional hydrogel with pH-sensitive optical fibers is developed for real-time wound monitoring and treatment of bacterial infections. The hydrogel exhibits good adhesion and self-healing properties, as well as a high antibacterial effect. It also provides reliable pH information to intelligent devices for monitoring the healing status.
ADVANCED FUNCTIONAL MATERIALS
(2023)
Article
Multidisciplinary Sciences
Maobin Xie, Liming Lian, Xuan Mu, Zeyu Luo, Carlos Ezio Garciamendez-Mijares, Zhenrui Zhang, Arturo Lopez, Jennifer Manriquez, Xiao Kuang, Junqi Wu, Jugal Kishore Sahoo, Federico Zertuche Gonzalez, Gang Li, Guosheng Tang, Sushila Maharjan, Jie Guo, David L. Kaplan, Yu Shrike Zhang
Summary: This study demonstrates the rapid volumetric printing of unmodified silk sericin and silk fibroin inks, which exhibit shape-memory and tuneable mechanical properties. The inks are cytocompatible, providing expanded bioink libraries for volumetric additive manufacturing and offering potential for diverse biomedical applications.
NATURE COMMUNICATIONS
(2023)
Article
Engineering, Environmental
Jing Liu, Junze Zhang, Zeyu Zhao, Yanping Liu, Wai Cheong Tam, Zhaozhu Zheng, Xiaoqin Wang, Yuling Li, Zekun Liu, Yi Li, Gang Li
Summary: In this study, a strain sensor using silk/polyurethane composite yarns with a core-sheath structure was designed and fabricated. The sensor exhibited fast response speed (80 ms), high durability (>1500 cycles), remarkable linear sensing feature (R2 = 99.8%) throughout the whole working range, and negative resistance response towards strain deformation. Moreover, it was not affected by temperature and humidity changes in typical use conditions. Experimental results showed its huge potentials for future personalized healthcare and public health management.
CHEMICAL ENGINEERING JOURNAL
(2023)
Article
Materials Science, Textiles
Muhammad Tauseef Khawar, Hugh Gong, Qasim Zia, Hafiza Hifza Nawaz, Jiashen Li
Summary: A three-layer composite respiratory filter was developed using a combination of polypropylene nonwoven layers and chitosan nanofibres. The impact of surface activation on filtration performance was studied using low-pressure plasma treatment. The treated samples showed higher filtration efficiency and quality factor due to a more effective capturing mechanism.
FIBERS AND POLYMERS
(2023)
Article
Chemistry, Multidisciplinary
Guanlin Li, Zehao Li, Yajun Min, Shilu Chen, Ruijia Han, Zheng Zhao
Summary: Researchers have developed 3D-printed piezoelectric scaffolds using shape memory polymer (SMP) and piezoelectric nanoparticles for bone defect repair. By incorporating Ag-TMSPM-pBT (ATP) nanoparticles, they were able to improve the piezoelectric properties of the scaffolds. In vitro and in vivo experiments showed that the scaffolds promoted osteogenic differentiation of bone cells and facilitated bone defect repair.
Article
Materials Science, Multidisciplinary
Jinlin Chang, Chen Meng, Bowen Shi, Wenyuan Wei, Renzhi Li, Jinmin Meng, Haobin Wen, Xiangyu Wang, Jun Song, Zhirun Hu, Zekun Liu, Jiashen Li
Summary: In this study, an ultra-thin, flexible, and porous Cu/PLLA fibrous membrane was developed with excellent breathability and high electrical conductivity. The membrane showed fast electrical heating characteristics and effective thermal conductivity for thermal management, as well as enhanced electromagnetic interference shielding effectiveness. It has great potential for future portable electronic devices and wearable integrated garments.
JOURNAL OF MATERIALS SCIENCE & TECHNOLOGY
(2023)
Article
Chemistry, Analytical
Huibin Zhang, Haiyang Yu, Minghua Deng, Zhanpeng Ren, Ziqin Li, Lei Zhang, Jiashen Li, Erjing Wang, Xianbao Wang, Jinhua Li
Summary: A new type of solution-gated graphene transistor was developed for highly sensitive and real-time detection of sialic acid (SA) by binding boric acid groups to diol monosaccharides. The sensor demonstrated a sensitivity of 10-19 M and a good linear relationship between the electrical current response and logarithmic values of SA concentrations in the range of 10-19 M to 10-5 M. It also exhibited excellent selectivity, stability, and potential for clinical application.
MICROCHEMICAL JOURNAL
(2023)
Article
Chemistry, Applied
Jinmin Meng, Ting Liu, Chen Meng, Zihan Lu, Jiashen Li
Summary: Based on polyacrylonitrile (PAN)/poly(vinylpyrrolidone) (PVP) electrospun precursor fibres, an efficient and cost-effective pore generation approach was developed to produce porous carbon nanofibres (PCNFs) with humidity sensing potential. The solid PAN/PVP fibres were transformed into porous ones with higher surface areas through the collective effects of crystallisation of PAN and dissolution of PVP. PCNFs film showed promising future as a stable and reactive humidity sensor.
MICROPOROUS AND MESOPOROUS MATERIALS
(2023)
Article
Materials Science, Biomaterials
Ruijia Han, Yajun Min, Guanlin Li, Shilu Chen, Maobin Xie, Zheng Zhao
Summary: In this study, CM-PDA/SF/nHA nanofibrous scaffolds loaded with curcumin modified polydopamine nanoparticles and silk fibroin doped with nano-hydroxyapatite were developed for bone defect regeneration and chemo-photothermal synergistic effects against osteosarcoma. The results showed that CM-PDA/SF/1%nHA scaffolds had good photothermal conversion efficiency and photostability, and they also exhibited the most obvious promotion effect on early osteogenic differentiation. Furthermore, these scaffolds could promote the proliferation and differentiation of bone marrow mesenchymal stem cells in vitro and new bone production in vivo.
BIOMATERIALS SCIENCE
(2023)
Article
Environmental Sciences
Ting Liu, Zihan Lu, Heng Zhai, Jinmin Meng, Jun Song, Yan Zhang, Jingang Liu, Jiashen Li
Summary: Hierarchical porous poly(L-lactic acid) PLLA@ TiO2 fibrous membranes were fabricated using electrospinning/post-treatment method. The induced crystallization of PLLA chains in acetone post-treatment created a unique blooming porous structure, increasing the specific surface area and exposing TiO2 nanoparticles on the fiber surface. The porous PLLA@TiO2-0.1 membrane with a PLLA:TiO2 weight ratio of 1:5 achieved the highest photocatalytic efficiency.
Article
Optics
Xie Mao-Bin, Wu Zhi-Yong, Cui Heng-Yi, Zhao Xin-Chao, Xuan Zhi-Yi, Liu Qing-Quan, Liu Feng, Sun Liao-Xin, Wang Shao-Wei
Summary: In this paper, an on-site method for determining the optical constants of thin films is proposed. By monitoring the transmittance of depositing materials, this method can rapidly and accurately determine the optical constants. Near-infrared optical constants of different materials were obtained using this method, demonstrating its suitability for measuring various absorption materials.
JOURNAL OF INFRARED AND MILLIMETER WAVES
(2022)
Article
Chemistry, Physical
P. Belmonte, J. M. Garcia-Vargas, J. F. Rodriguez, I. Garrido, M. T. Garcia, M. J. Ramos
Summary: In this study, four polythiourethane films with different types of polyols and isocyanates were synthesized, characterized, and foamed. The results showed that the type of isocyanate greatly influenced the crystallinity and stiffness of the polymers, while the type of polyol modified the FT-IR spectra and the decomposition curve of the material with temperature. Furthermore, the choice of isocyanate also affected the properties of the foams obtained from the polymeric material.
JOURNAL OF SUPERCRITICAL FLUIDS
(2024)
Article
Chemistry, Physical
Xutao Zhu, Jianguo Yan, Shouchun Liu, Fengling Zhu
Summary: This study experimentally assessed the hydrodynamic characteristics of supercritical-pressure R134a in a horizontal circular tube. It was found that the hydrodynamic characteristic curve of R134a under supercritical pressure does not have a negative-slope region but a transition region. The transition region becomes more evident with increasing heat flux, while it weakens with increasing pressure and inlet temperature. Moreover, the onset of the transition region shifts in the direction of high mass flow rate with increasing heat flux.
JOURNAL OF SUPERCRITICAL FLUIDS
(2024)
Article
Chemistry, Physical
Stefania Mottola, Iolanda De Marco
Summary: In this study, corticosteroids were micronized with cyclodextrin using Supercritical Assisted Atomization (SAA), resulting in spherical micrometric particles with improved dissolution time.
JOURNAL OF SUPERCRITICAL FLUIDS
(2024)
Article
Chemistry, Physical
Honghai Liu, Yu Xie, Zhilan Li, Xiaokai Zhang
Summary: This study compared the effects of supercritical carbon dioxide dewatering (SCD) and conventional kiln drying (CKD) at a temperature of 55 degrees C on the dewatering rate, moisture transfer and distribution, shrinkage, and stress characteristics of bamboo strips. The results showed that SCD had a faster dewatering rate and lower shrinkage compared to CKD, but was less effective in reducing drying stress in bamboo.
JOURNAL OF SUPERCRITICAL FLUIDS
(2024)
Article
Chemistry, Physical
Tahmasb Hatami, Ozan N. Ciftci
Summary: This study fills the gap in previous research by establishing a hierarchy of significance for factors affecting SFE profitability, providing a deeper understanding of how technical and economic factors impact profitability. The findings highlight that the SFE facility becomes profitable when the extractor capacity surpasses 42 L.
JOURNAL OF SUPERCRITICAL FLUIDS
(2024)
Article
Chemistry, Physical
Tingshan Guo, Chuang He, Zhiyuan Liang, Qinxin Zhao
Summary: The initial oxidation behavior of Fe10Cr and Fe20Cr alloys in supercritical H2O and supercritical CO2 with O2 has been investigated. The results show that O2 has the highest adsorption energy on FeCr alloys and reacts faster than H2O and CO2.
JOURNAL OF SUPERCRITICAL FLUIDS
(2024)
Article
Chemistry, Physical
Vikash Chandra Roy, Jin-Seok Park, Ahmed Redwan Haque, Md Sadek Ali, Hee-Jeong Lee, Byung-Soo Chun
Summary: This research aimed to valorize brewery spent grain (BSG) using subcritical water hydrolysis (SWH) modified by six different natural deep eutectic solvents (DES) and determining their bipotentialities. The findings showed that BSG hydrolysates obtained through DES-induced SWH contained high levels of sugars, proteins, flavonoids, phenolic compounds, and essential amino acids. The hydrolysates also demonstrated antimicrobial activities, and the presence of bioactive compounds was confirmed through FT-IR analysis. This comprehensive profiling of bioactive compounds from BSG using DES-mediated SWH can contribute to the efficient valorization of BSG for industrial purposes.
JOURNAL OF SUPERCRITICAL FLUIDS
(2024)
Article
Chemistry, Physical
Kailiang Zhang, Hanyu Wang, Tong Liu, Zhu Wang, Lvxing Wang, Ping Fan, Feng Chen, Mingqiang Zhong, Bozhen Wu, Shanqiu Liu, Jintao Yang
Summary: This study investigates the influence of foam cell structure on the electromagnetic interference shielding performance of conductive polymer composite foam. The results suggest that foamed composites exhibit improved EMI shielding performance, and bimodal cell foams have higher electric conductivity but lower EMI shielding compared to uniform cell foams.
JOURNAL OF SUPERCRITICAL FLUIDS
(2024)
Article
Chemistry, Physical
Jaromir Valtr, Petr Roztocil, David Dasek, Radek Musalek, Frantisek Lukac, Jakub Klecka, Marek Janata, Mariana Arnoult-Ruzickova, Eva Mistova, Ludek Jelinek, Petr Sajdl, Jan Macak
Summary: This paper focuses on the design of an experimental facility for in-situ electrochemical testing at supercritical water conditions, including the design of the electrode system and surface insulation coating for electrode leads.
JOURNAL OF SUPERCRITICAL FLUIDS
(2024)
Article
Chemistry, Physical
Richard Djimasbe, Mikhail A. Varfolomeev, Nailya M. Khasanova, Ameen A. Al-Muntaser, Rustam R. Davletshin, Muneer A. Suwaid, Gazinur Z. Mingazov
Summary: This study confirms the capability of supercritical water to generate active hydrogen that interacts with different fractions in unconventional feedstocks, leading to synthetic oil production during hydrothermal reactions. The findings suggest that a maximum yield of 16.78% can be achieved at a temperature of 380 oC and a reaction time of 1-12 hours.
JOURNAL OF SUPERCRITICAL FLUIDS
(2024)
