Pharmacokinetic interaction studies of co-administration of ticagrelor and atorvastatin or simvastatin in healthy volunteers

Pharmacokinetics, pharmacodynamics, safety and tolerability of multiple ascending doses of ticagrelor in healthy volunteers

(2010) Kathleen Butler et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Development of a Population Pharmacokinetic Model for Atorvastatin Acid and Its Lactone Metabolite

(2010) Rajesh Narwal et al.   CLINICAL PHARMACOKINETICS

In Vitro Evaluation of Potential Drug-Drug Interactions with Ticagrelor: Cytochrome P450 Reaction Phenotyping, Inhibition, Induction, and Differential Kinetics

(2010) D. Zhou et al.   DRUG METABOLISM AND DISPOSITION

Absorption, Distribution, Metabolism, and Excretion of Ticagrelor in Healthy Subjects

(2010) R. Teng et al.   DRUG METABOLISM AND DISPOSITION

Pharmacokinetics, pharmacodynamics, tolerability and safety of single ascending doses of ticagrelor, a reversibly binding oral P2Y12 receptor antagonist, in healthy subjects

(2010) Renli Teng et al.   EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY

Determination of ticagrelor and two metabolites in plasma samples by liquid chromatography and mass spectrometry

(2010) Henrik Sillén et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Ticagrelor: The First Reversibly Binding Oral P2Y12Receptor Antagonist

(2009) Steen Husted et al.   Cardiovascular Therapeutics

Ticagrelor versus Clopidogrel in Patients with Acute Coronary Syndromes

(2009) Lars Wallentin et al.   NEW ENGLAND JOURNAL OF MEDICINE

ABCB1 Haplotypes Differentially Affect the Pharmacokinetics of the Acid and Lactone Forms of Simvastatin and Atorvastatin

(2008) JE Keskitalo et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Interaction between statins and clopidogrel: is there anything clinically relevant?

(2008) R. Bhindi et al.   QJM-AN INTERNATIONAL JOURNAL OF MEDICINE

Contribution of cytochrome P450 3A4 and 3A5 to the metabolism of atorvastatin

(2008) J.-E. Park et al.   XENOBIOTICA