Article
Public, Environmental & Occupational Health
Ke Peng, Weicong Cai, Xiaoying Liu, Yishu Liu, Yu Shi, Jessica Gong, Lin Lei, Ji Peng, Yuxin Xie, Honglei Zhao, Lei Si, Menglu Ouyang
Summary: This study analyzes the trends of hypercholesterolemia in Shenzhen, China from 1997 to 2018. The results show a downward linear trend in age-adjusted mean high-density lipoprotein-cholesterol (HDL-C) in both women and men. However, total triglycerides and total cholesterol have increased in the past two decades. There were no significant changes in age-adjusted low-density lipoprotein-cholesterol (LDL-C) between 2009 and 2018. The prevalence of hypercholesterolemia rapidly rose from 1997 to 2009 and then stabilized in 2018.
FRONTIERS IN PUBLIC HEALTH
(2022)
Article
Biochemistry & Molecular Biology
Anna E. Engell, Henrik L. Jorgensen, Bent S. Lind, Anton Pottegard, Christen L. Andersen, John S. Andersen, Margit Kriegbaum, Mia K. Grand, Lise Bathum
Summary: Lipid levels in blood have decreased significantly in the general population due to the use of statins. This trend was observed in primary health care patients who were not using statins from 2001 to 2018, with substantial decreases in total cholesterol and low-density lipoprotein cholesterol levels, especially in the elderly population.
LIPIDS IN HEALTH AND DISEASE
(2021)
Article
Public, Environmental & Occupational Health
Sang-Wook Yi, Se-Jun Park, Jee-Jeon Yi, Heechoul Ohrr, Hyeongsu Kim
Summary: The study found U-curve associations between HDL-C levels and mortality, regardless of sex or age. Younger adults had a lower optimal range and a stronger positive association with mortality in the high HDL-C range compared to older adults. Even moderately high HDL-C levels may not necessarily indicate good health, especially in young adults.
INTERNATIONAL JOURNAL OF EPIDEMIOLOGY
(2021)
Review
Chemistry, Applied
Hui Yang, Yezhi Qu, Yaran Gao, Shuyuan Sun, Ruixue Ding, Weihe Cang, Rina Wu, Junrui Wu
Summary: It is concerning that food allergies are becoming more common due to factors such as hygiene, microbiota, inappropriate complementary foods, and processed food consumption. Understanding the role of dietary components can improve the diagnosis, treatment, and prevention of food allergies.
Article
Medicine, General & Internal
Diego Casas-Deza, Ana Martinez-Sapina, Silvia Espina, Beatriz Garcia-Rodriguez, Eva M. Fernandez-Bonilla, Alejandro Sanz-Paris, Yolanda Gonzalez-Irazabal, Vanesa Bernal-Monterde, Jose M. Arbones-Mainar
Summary: DAA treatment improves plasma lipid levels and glycemic control in patients with HCV. Additionally, iron metabolism and coagulation function also improved. While two cardiovascular events were observed, overall DAA treatment did not increase the risk of cardiovascular events.
JOURNAL OF CLINICAL MEDICINE
(2022)
Review
Food Science & Technology
Seyedeh-Masomeh Derakhshandeh-Rishehri, Saeed Ghobadi, Masoumeh Akhlaghi, Shiva Faghih
Summary: Calcium supplement intake is associated with a significant reduction in low density lipoprotein cholesterol level, especially in individuals without dyslipidemia, higher calcium intakes, and longer period of consumption.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2022)
Review
Microbiology
Ivy Mallick, Pierre Santucci, Isabelle Poncin, Vanessa Point, Laurent Kremer, Jean-Francois Cavalier, Stephane Canaan
Summary: Mycobacterial species, such as Mycobacterium tuberculosis, rely on lipids for survival within their hosts, storing them as intrabacterial lipid inclusions (ILI). These ILI serve as a critical energy source under nutrient-limiting conditions, supporting bacterial survival for extended periods. Despite their importance, more research is needed to fully understand the metabolism and role of ILI in mycobacterial adaptation and survival during infection.
FEMS MICROBIOLOGY REVIEWS
(2021)
Review
Nutrition & Dietetics
Marta Guasch-Ferre, Anne-Julie Tessier, Kristina S. Petersen, Philip A. Sapp, Linda C. Tapsell, Jordi Salas-Salvado, Emilio Ros, Penny M. Kris-Etherton
Summary: In this comprehensive review, the authors summarize the current knowledge on the effects of nut consumption on blood lipids and lipoproteins. Meta-analyses of randomized controlled trials consistently show that most nuts, including walnuts, almonds, cashews, peanuts, and pistachios, have a beneficial effect on total cholesterol, LDL-cholesterol, and triglycerides. However, no effect on HDL-cholesterol is observed. Preliminary evidence suggests that adding nuts to the regular diet improves ApoB levels and HDL function. The evidence indicates that nut-enriched diets are associated with a reduced number of total LDL particles and small, dense LDL particles.
Article
Food Science & Technology
Shafiya Rafiq, Mohd Ishfaq Bhat, Sajad. A. Sofi, Khalid Muzzafar, Darakshan Majid, B. N. Dar, Hilal. A. Makroo
Summary: Population growth, global warming, and food scarcity have created a demand for alternative lipid sources. Utilizing agri-food waste and byproducts as a substrate for oleaginous microorganisms to produce microbial lipids is a sustainable approach. These microorganisms have advantages such as rapid growth, ease of cultivation, and adaptability to various substrates, making them a versatile raw material.
TRENDS IN FOOD SCIENCE & TECHNOLOGY
(2023)
Review
Nutrition & Dietetics
Seetha Anitha, Rosemary Botha, Joanna Kane-Potaka, D. Ian Givens, Ananthan Rajendran, Takuji W. Tsusaka, Raj Kumar Bhandari
Summary: The consumption of millets can reduce levels of total cholesterol, triacylglycerol, low-density lipoprotein cholesterol, and very-low-density lipoprotein cholesterol, helping to manage hyperlipidemia and hypertension while increasing levels of high-density lipoprotein cholesterol, which is beneficial for preventing cardiovascular diseases.
FRONTIERS IN NUTRITION
(2021)
Article
Multidisciplinary Sciences
Hao Wang, Joshua A. Kulas, Chao Wang, David M. Holtzman, Heather A. Ferris, Scott B. Hansen
Summary: The study shows that apoE uses astrocyte-derived cholesterol to traffic neuronal APP in and out of lipid clusters, generating A beta peptide. Deletion of astrocyte cholesterol synthesis reduces amyloid and tau burden in a mouse model of AD, indicating that cholesterol is kept low in neurons and astrocytes regulate A beta accumulation through cholesterol signaling.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2021)
Article
Fisheries
Masaki Kakimoto, Naoki Takatani, Masashi Hosokawa, Fumiaki Beppu
Summary: This study investigates the effects of a MADG-rich neutral lipid on the lipid metabolism of diabetic/obese KK-A(y) mice. The results show that MNB supplementation can decrease adipose tissue weights and blood glucose levels, and significantly lower serum lipid levels compared to the control and FO groups. The study provides new insights into the role of MADG as a nutraceutical and the effects of ether lipids on lipoprotein metabolism.
Review
Medicine, General & Internal
Agnieszka Kulak-Bejda, Grzegorz Bejda, Magdalena Lech, Napoleon Waszkiewicz
Summary: Suicide and suicidal behaviors are serious global problems, with lipids playing an important role and possibly acting as a biological marker for suicide. Various studies have attempted to identify biological markers related to suicidal behavior, with metabolic deregulation, particularly low lipid levels, potentially increasing suicide risk in patients with psychiatric disorders.
JOURNAL OF CLINICAL MEDICINE
(2021)
Review
Biotechnology & Applied Microbiology
Pooria Nakhaei, Ria Margiana, Dmitry O. Bokov, Walid Kamal Abdelbasset, Mohammad Amin Jadidi Kouhbanani, Rajender S. Varma, Faroogh Marofi, Mostafa Jarahian, Nasrin Beheshtkhoo
Summary: Liposomes are a type of nanoparticles with a phospholipid membrane, rich in lipid contents, where cholesterol plays a vital role in stability. Despite various applications of liposomes, stability limitations still exist due to ingredient influence.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2021)
Article
Cardiac & Cardiovascular Systems
Fabian Eichelmann, Laury Sellem, Clemens Wittenbecher, Susanne Jaeger, Olga Kuxhaus, Marcela Prada, Rafael Cuadrat, Kim G. Jackson, Julie A. Lovegrove, Matthias B. Schulze
Summary: This study assessed the associations between plasma lipids and cardiometabolic diseases and found several lipids associated with disease risk. The study also tested the effect of dietary fat modification on these lipids and found that unsaturated fatty acids may have a beneficial effect on long-term cardiometabolic risk prevention.