期刊
EUROPEAN JOURNAL OF CLINICAL NUTRITION
卷 63, 期 9, 页码 1150-1153出版社
NATURE PUBLISHING GROUP
DOI: 10.1038/ejcn.2009.18
关键词
vitamin D supplementation; HDL-cholesterol; LDL-cholesterol; total cholesterol; triacylglycerol; Pakistani immigrants
资金
- European Fifth Framework Programme [QLK1-CT-2000-00623]
- National Food Institute, Technical University of Denmark
Potential long-term negative effects of increased vitamin D consumption are not thoroughly examined. The aim of this study was to investigate possible negative effects of vitamin D supplementation on serum lipids and lipoproteins. A 1-year long randomised double-blinded placebo-controlled intervention study with two doses of vitamin D3 (10 and 20 mu g/day) was carried out among 89 women (18-53 years of age) and 84 men (18-64 years of age) of Pakistani origin living in Denmark with low vitamin D status. This study did not find changes in total cholesterol, LDL-cholesterol, HDL-cholesterol, LDL-cholesterol/HDL-cholesterol ratio, VLDL-cholesterol and triacylglycerol after daily supplementation with 10 or 20 mu g vitamin D for 1 year. In conclusion, increasing the vitamin D intake by 10-20 mu g per day for 1 year is safe for Pakistani immigrants with regards to serum lipids and lipoproteins. European Journal of Clinical Nutrition (2009) 63, 1150-1153; doi:10.1038/ejcn.2009.18; published online 8 April 2009
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