Article
Immunology
Junli Jia, Lisha Huang, Long Zhang, Yanbing Sheng, Weili Chu, Hao Xu, Aiguo Xu
Summary: The occurrence and transmission of carbapenemase-producing Enterobacterales (CPE) on a global scale is a major concern. This study investigates the resistance and transmission dynamics of two carbapenem-resistant Serratia marcescens isolates causing bacteremia in China. The isolates were found to produce KPC-2 and had a resistance to various antibiotics. Whole-genome sequencing and plasmid analysis revealed the presence of bla(KPC-2)-bearing IncR plasmids and multiple plasmid-borne antimicrobial resistance genes. The findings highlight the emergence of bla(KPC-2)-bearing IncR plasmid as a potential hindrance to the transmission of KPC-2-producing S. marcescens in clinical settings.
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY
(2023)
Article
Microbiology
Celia Leao, Lurdes Clemente, Laura Moura, Anne Mette Seyfarth, Inge M. Hansen, Rene S. Hendriksen, Ana Amaro
Summary: The study identified CTX-M-65-producing E. coli strains in food products of animal origin in Portugal. These strains share identical genetic environment, resistance genes, and plasmids, indicating possible common origins and transmission routes.
FRONTIERS IN MICROBIOLOGY
(2021)
Article
Microbiology
Mehrdad Halaji, Shahrzad Shahidi, Behrooz Ataei, Abdolamir Atapour, Awat Feizi, Seyed Asghar Havaei
Summary: This study investigated the phylogenetic characterization and virulence traits of uropathogenic Escherichia coli (UPEC) isolated from kidney transplant patients (KTPs) and non-KTPs, as well as analyzed the clonal distribution of Extended Spectrum Beta-Lactamases (ESBLs)-producing UPEC with bla(CTX-M) gene. The results showed differences in virulence factor gene prevalence between KTPs and non-KTPs, with the most common UPEC phylogenetic groups being B-2, D, and A. Furthermore, MLST analysis identified 18 unique sequence types in ESBL-producing isolates, with ST131 being the most prevalent type.
ANNALS OF CLINICAL MICROBIOLOGY AND ANTIMICROBIALS
(2021)
Article
Infectious Diseases
Selene Rebecca Boncompagni, Maria Micieli, Tiziana Di Maggio, Antonia Mantella, Anna Liz Villagran, Tatiana Briggesth Miranda, Carmen Revollo, Veronica Poma, Herlan Gamboa, Michele Spinicci, Marianne Strohmeyer, Alessandro Bartoloni, Gian Maria Rossolini, Lucia Pallecchi
Summary: This study examined the fecal carriage of CTX-M-producing Enterobacterales in school-aged children from rural areas of the Bolivian Chaco. The results showed a significant increase in the fecal carriage of CTX-M-producing Enterobacterales from 2016 to 2019. The study highlights the importance of understanding the dissemination dynamics of this resistance determinant.
INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES
(2022)
Article
Immunology
Cecile Emeraud, Delphine Girlich, Remy A. Bonnin, Agnes B. Jousset, Thierry Naas, Laurent Dortet
Summary: Since 2016, OXA-244-producing Escherichia coli has been increasingly isolated in France. Sequencing of 97 OXA-244-producing E. coli isolates revealed a wide diversity of sequence types with a high prevalence of sequence type 38. Long-read sequencing confirmed the chromosomal location of bla(OXA-244) within the entire or truncated Tn51098.
EMERGING INFECTIOUS DISEASES
(2021)
Article
Microbiology
Francesca Leoni, Luca Sacchini, Silvia Pieralisi, Gabriele Angelico, Chiara Francesca Magistrali, Lucilla Cucco, Francesca Romana Massacci, Elisa Albini, Anna Duranti, Cesare Camma, Barbara Secondini, Antonio Rinaldi, Francesca Barchiesi
Summary: This study investigated the occurrence of ESBL-producing E. coli in clams collected from the Central Adriatic Sea. The results showed that approximately 3% of the samples contained ESBL-producing E. coli, with the majority of the isolates being multidrug-resistant. These findings suggest that E. coli could serve as an indicator organism for ESBL-producing E. coli in bivalves.
FRONTIERS IN MICROBIOLOGY
(2023)
Article
Infectious Diseases
Isabel Carvalho, Rita Cunha, Carla Martins, Sandra Martinez-Alvarez, Nadia Safia Chenouf, Paulo Pimenta, Ana Raquel Pereira, Sonia Ramos, Madjid Sadi, Angela Martins, Jorge Facanha, Fazle Rabbi, Rosa Capita, Carlos Alonso-Calleja, Maria de Lurdes Nunes Enes Dapkevicius, Gilberto Igrejas, Carmen Torres, Patricia Poeta
Summary: This study analyzed the prevalence and genetic characteristics of ESBL and acquired-AmpC producing Escherichia coli isolates from healthy and sick dogs in Portugal. The results showed different bla(CTX-M) genes variants among ESBL-producers, as well as the presence of CMY-2 beta-lactamase in some isolates. Dogs were found to be carriers of ESBL and/or qAmpC-producing E. coli, with a potential zoonotic role.
Article
Agriculture, Dairy & Animal Science
Zoi Athanasakopoulou, Marina Sofia, Alexios Giannakopoulos, Konstantinos Papageorgiou, Dimitris C. Chatzopoulos, Vassiliki Spyrou, Evanthia Petridou, Efthymia Petinaki, Charalambos Billinis
Summary: M. wisconsensis was found in wild birds in Greece, but not in humans. Some strains showed resistance to multiple antibiotics and carried the CTX-M-1 gene.
Article
Microbiology
Haoyu Ge, Jie Qiao, Hao Xu, Ruishan Liu, Ruyan Chen, Chenyu Li, Xinjun Hu, Jiawei Zhou, Xiaobing Guo, Beiwen Zheng
Summary: This study reported for the first time the coexistence of bla(OXA-181), bla(CTX-M-55), and mcr-8 in an ST273 Klebsiella pneumoniae isolate. Various antimicrobial resistance genes (ARGs) and virulence genes were detected using PCR and whole-genome sequencing, and antimicrobial susceptibility testing showed resistance to multiple antibiotics. The presence of these genes on plasmids suggests the potential for their propagation.
FRONTIERS IN MICROBIOLOGY
(2022)
Article
Microbiology
Racha Beyrouthy, Carolina Sabenca, Frederic Robin, Patricia Poeta, Giberto Igrejas, Richard Bonnet
Summary: This study investigated the spread of Escherichia coli containing the resistance gene bla(CTX-M-1) in different habitats and wild fauna using a genomic approach. The results indicated that CTX-M-1 E. coli were preferentially associated with specific ecosystems, and the IncI1-ST3-bla(CTX-M-1) plasmids were disseminated among all E. coli phylogroups with main divergences located in a recombination region containing bla(CTX-M-1).
Article
Immunology
Faustinos Tatenda Takawira, Johann D. D. Pitout, Gaetan Thilliez, Tapfumanei Mashe, Ana Victoria Gutierrez, Robert A. Kingsley, Gisele Peirano, Jorge Matheu, Stanley Munyaradzi Midzi, Lusubilo Witson Mwamakamba, David L. Gally, Andrew Tarupiwa, Leckson Mukavhi, Marthie M. Ehlers, Sekesai Mtapuri-Zinyowera, Marleen M. Kock
Summary: This study investigated the carriage of ESBL producing and colistin resistant E. coli in poultry in Zimbabwe. The study found a diverse group of ESBL producing E. coli strains in poultry, with the presence of multiple antibiotic resistance genes. This is the first report of mcr-1 in Zimbabwe, highlighting the importance of the One Health approach in controlling antibiotic resistance spread.
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY
(2022)
Article
Infectious Diseases
Mario Galindo-Mendez, Humberto Navarrete-Salazar, Francisco Baltazar-Jimenez, Eduardo Munoz-de La Paz, Maria Fernanda Sanchez-Mawcinitt, Alexis Gomez-Pardo, Elvira Garza-Gonzalez, Luis Alfredo Ponce-de-Leon-Garduno, Rafael Franco-Cendejas, Rayo Morfin-Otero, Fabian Rojas-Larios, Juan Pablo Mena-Ramirez, Cecilia Teresita Morales-de-la-Pena, Lourdes Garcia-Mendoza, Elena Victoria Choy-Chang, Laura Karina Aviles-Benitez, Eduardo Lopez-Gutierrez, Jorge Luis Canizales-Oviedo, Nicolas Eric Barlandas-Rendon, Joyarib Yanelli Maldonado-Anicacio, Alina Aracely Rosales-Garcia, Heidy Leticia Ostos-Cantu
Summary: This study investigated the resistance mechanisms of ESBL-producing E. coli strains against fosfomycin. The results showed that fosA3 and fosA1 genes played important roles in fosfomycin resistance, and there was a strong association between fos and bla(CTX-M) genes and ST131 clones in uropathogenic E. coli.
Article
Infectious Diseases
Rebecca A. Gladstone, Alan McNally, Anna K. Pontinen, Gerry Tonkin-Hill, John A. Lees, Kusti Skyten, Francois Cleon, Martin O. K. Christensen, Bjorg C. Haldorsen, Kristina K. Bye, Karianne W. Gammelsrud, Reidar Hjetland, Angela Kummel, Hege E. Larsen, Paul Christoffer Lindemann, Iren H. Lohr, Ashild Marvik, Einar Nilsen, Marie T. Noer, Gunnar S. Simonsen, Martin Steinbakk, Stale Tofteland, Marit Vattoy, Stephen D. Bentley, Nicholas J. Croucher, Julian Parkhill, Pal J. Johnsen, Orjan Samuelsen, Jukka Corander
Summary: This study found that CC131 clade A isolates, predominantly antimicrobial susceptible, were established early and sustained, indicating that resistance is not necessary for clonal success. However, in the low antibiotic use setting of Norway, resistance to important antimicrobial classes has rapidly been selected for in CC131 clade A isolates. This underscores the importance of genomic surveillance in understanding the complex ecology of multidrug resistance dissemination and competition.
Article
Immunology
Zhen-Yu Wang, Yue Jiang, Yi-Qiao Shao, Heng-Fan Lu, Meng-Jun Lu, Xinan Jiao, Jing Wang, Qiu-Chun Li
Summary: This study investigates the prevalence and dissemination mechanism of ESBL-producing E. coli from healthy individuals in a community in Yangzhou, China. The study found nasal colonization of CTX-M-55-producing E. coli strains among healthy individuals in the community, indicating a potential risk of antimicrobial resistance dissemination through close contact or environmental transmission.
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY
(2022)
Article
Infectious Diseases
Amel Mhaya, Rahma Trabelsi, Sabine Aillerie, Fatima M'Zali, Dominique Begu, Slim Tounsi, Radhouane Gdoura, Corinne Arpin
Summary: Multiple ESBL-producing strains were identified in Tunisian patients, including two emerging virulent clones, ST131-C2 and ST131-C1-M27, which were found to be prevalent in both community and hospital settings.
Article
Infectious Diseases
R. Izdebski, J. Fiett, P. Urbanowicz, A. Baraniak, L. P. G. Derde, M. J. M. Bonten, Y. Carmeli, H. Goossens, W. Hryniewicz, C. Brun-Buisson, S. Brisse, M. Gniadkowski
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
(2015)
Article
Infectious Diseases
Yoav Barnea, Anat Lerner, Asaf Aizic, Shiri Navon-Venezia, Eleanor Rachi, Michael W. Dunne, Sailaja Puttagunta, Yehuda Carmeli
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
(2016)
Article
Infectious Diseases
C. C. Papagiannitsis, R. Izdebski, A. Baraniak, J. Fiett, M. Herda, J. Hrabak, L. P. G. Derde, M. J. M. Bonten, Y. Carmeli, H. Goossens, W. Hryniewicz, C. Brun-Buisson, M. Gniadkowski
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
(2015)
Article
Veterinary Sciences
Sharon Tirosh-Levy, Amir Steinman, Yehuda Carmeli, Eyal Klement, Shiri Navon-Venezia
PREVENTIVE VETERINARY MEDICINE
(2015)
Article
Microbiology
Ella Kaplan, Noa Sela, Adi Doron-Faigenboim, Shiri Navon-Venezia, Edouard Jurkevitch, Eddie Cytryn
FRONTIERS IN MICROBIOLOGY
(2015)
Article
Microbiology
Kira Kondratyeva, Ayala Wollman, Gabi Gerlitz, Shiri Navon-Venezia
JOURNAL OF MEDICAL MICROBIOLOGY
(2017)
Article
Surgery
Yoav Barnea, Dennis C. Hammond, Yuval Geffen, Shiri Navon-Venezia, Keren Goldberg
AESTHETIC SURGERY JOURNAL
(2018)
Article
Infectious Diseases
Amos Adler, Omar Hussein, Debby Ben-David, Samira Masarwa, Shiri Navon-Venezia, Mitchell J. Schwaber, Yehuda Carmeli
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
(2015)
Article
Infectious Diseases
R. Izdebski, A. Baraniak, M. Herda, J. Fiett, M. J. M. Bonten, Y. Carmeli, H. Goossens, W. Hryniewicz, C. Brun-Buisson, M. Gniadkowski
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
(2015)
Article
Infectious Diseases
Tal Brosh-Nissimov, Shiri Navon-Venezia, Nathan Keller, Sharon Amit
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
(2019)
Article
Clinical Neurology
Nina Feinstein, Reuven Tyk, Olga Touloumi, Roza Lagoudaki, Yehuda Goldberg, Oryan Agranyoni, Shiri Navon-Venezia, Abram Katz, Nikolaos Grigoriadis, Tamir Ben-Hur, Ofira Einstein
ANNALS OF CLINICAL AND TRANSLATIONAL NEUROLOGY
(2019)
Article
Agriculture, Dairy & Animal Science
Anat Shnaiderman-Torban, Yossi Paitan, Haia Arielly, Kira Kondratyeva, Sharon Tirosh-Levy, Gila Abells-Sutton, Shiri Navon-Venezia, Amir Steinman
Article
Microbiology
Anat Shnaiderman-Torban, Amir Steinman, Gal Meidan, Yossi Paitan, Wiessam Abu Ahmad, Shiri Navon-Venezia
FRONTIERS IN MICROBIOLOGY
(2019)
Article
Chemistry, Multidisciplinary
Edward Bormashenko, Irina Legchenkova, Shiri Navon-Venezia, Mark Frenkel, Yelena Bormashenko
Summary: The impact of different plasma treatments on medical grade polyvinylchloride in terms of wettability and chemical composition was studied. Corona plasma treatment significantly enhanced its hydrophilic properties, while oxidation was hardly correlated with hydrophobic recovery, mainly attributable to the bulk mobility of polymer chains.
APPLIED SCIENCES-BASEL
(2021)
Review
Microbiology
Shiri Navon-Venezia, Kira Kondratyeva, Alessandra Carattoli
FEMS MICROBIOLOGY REVIEWS
(2017)