Article
Chemistry, Applied
Hannington Ngabirano, Grace Birungi
Summary: The study revealed that pesticide residues in vegetables produced in rural South-western Uganda exceeded Maximum Residue Limits in a significant percentage of samples, posing potential risks to food quality and human health. Therefore, regulatory measures and monitoring of pesticide residues in vegetables from this region are essential to prevent adverse effects on human health.
Article
Water Resources
Alex Saturday, Thomas J. Lyimo, John Machiwa, Siajali Pamba
Summary: This study used a numerical model to determine the processes governing nitrogen transformation in Lake Bunyonyi. The model accurately predicted the lake's behavior and suggested further investigation into nutrient and water inflow sources.
APPLIED WATER SCIENCE
(2022)
Article
Nutrition & Dietetics
Laura Gramantieri, Federica Gnudi, Francesco Vasuri, Daniele Mandrioli, Francesca Fornari, Francesco Tovoli, Fabrizia Suzzi, Andrea Vornoli, Antonia D'Errico, Fabio Piscaglia, Catia Giovannini
Summary: The study indicated that chronic/intermittent, low-dose AFB1 consumption may lead to accumulation in the liver and contribute to liver cancer in low-exposure areas. AFB1-DNA adducts were mainly found in liver tissues of HCC patients, suggesting the importance of detection and control measures for aflatoxins to ensure food safety in low exposure areas.
Article
Multidisciplinary Sciences
Tugume Peterson Gordon, Muhwezi Talbert, Maud Kamatenesi Mugisha, Ainamani Elvis Herbert
Summary: This study aimed to investigate HIV viral suppression levels among adolescents in Kabale district and the associated clinical, adherence, and psychosocial factors. The findings showed that factors such as good nutrition status, absence of severe opportunistic infections, no treatment interruptions, participation in support groups, and support from family members were significantly associated with viral load suppression.
Article
Water Resources
Alex Saturday, Thomas J. Lyimo, John Machiwa, Siajali Pamba
Summary: The study assessed the variations in the trophic state condition of Lake Bunyonyi over a period of one year. The results showed that the lake was eutrophic in both dry and wet seasons, possibly due to nutrients inflow from farmlands. The study recommends the development of guidelines for trophic status monitoring of the lake.
APPLIED WATER SCIENCE
(2023)
Article
Public, Environmental & Occupational Health
Raymond Bernard Kihumuro, David Jolly Muganzi, Elton George Wandira, Racheal Alinaiswe, Jovitah Joselyne Nanyunja, Ruth Kugumisiriza, Paul E. Alele, Vincent Mubangizi
Summary: The number of HIV positive adolescents in secondary schools has increased over the years. This study explored the factors surrounding their anti-retroviral therapy adherence and challenges faced by these students in boarding secondary schools. Limited disclosure of HIV status has proven useful, but some students have opted not to disclose their status and used negative coping mechanisms.
Article
Chemistry, Applied
Jian Sun, Xueping Ning, Lanyu Cui, Wenhui Qin, Wenxu Wang, Shengbin He
Summary: In this study, a reproductive switch DNA template was developed for the precise quantification of aflatoxins. The method demonstrated high sensitivity, good anti-interference abilities, and specificity towards aflatoxin B1. It was successfully applied for the quantification of aflatoxin B1 in complex food samples.
Article
Agriculture, Multidisciplinary
Sylvia Nabasumba, Margaret Najjingo Mangheni, Johnny Mugisha, Pamela Pali, Florence Birungi Kyazze, Prossy Isubikalu
Summary: This study identified homogeneous typologies of seed potato producers investing in seed potato production in South-Western Uganda using principal component and cluster analysis methods. The results revealed four different types of seed potato producers with distinct characteristics, as well as identifying common factors that constrain investment in seed production.
INTERNATIONAL JOURNAL OF AGRICULTURAL SUSTAINABILITY
(2023)
Article
Multidisciplinary Sciences
Emmanuel Nshakira-Rukundo, Essa Chanie Mussa, Min Jung Cho
Summary: The aim of the study is to understand factors associated with dropping out of Community Based Health Insurance (CBHI) schemes in Uganda, with findings pointing to household socioeconomic status, household size, distance from hospital, and social connections as key factors influencing dropping out. The results have implications for addressing equity and inclusion concerns in CBHI programmes.
Article
Multidisciplinary Sciences
Barbra Tuhamize, Benon B. Asiimwe, Kennedy Kasaza, Wilber Sabiiti, Mathew Holden, Joel Bazira
Summary: This study found that a high percentage of Escherichia coli strains isolated from humans and livestock in rural south western Uganda carry the blaKPC gene, with a significant proportion of strains not actively expressing the gene. The results suggest that besides the KPC gene, other mechanisms may be involved in carbapenem resistance.
Article
Multidisciplinary Sciences
Leevan Tibaijuka, Stephen M. Bawakanya, Asiphas Owaraganise, Lydia Kyasimire, Elias Kumbakumba, Adeline A. Boatin, Musa Kayondo, Joseph Ngonzi, Stephen B. Asiimwe, Godfrey R. Mugyenyi
Summary: High mortality rate among preterm neonates born at Mbarara Regional Referral Hospital in Uganda, with modifiable predictors such as lack of ANC attendance, birth asphyxia, respiratory distress syndrome, delayed initiation of breastfeeding, etc. Interventions such as kangaroo mother care, early initiation of breastfeeding, and timely resuscitation could improve outcomes for preterm neonates in this setting.
Review
Food Science & Technology
Abdoulie Jallow, Huali Xie, Xiaoqian Tang, Zhang Qi, Peiwu Li
Summary: Aflatoxins, produced by fungal species from the Aspergillus genus, pose a global health and economic concern due to their toxic, mutagenic, and carcinogenic properties, which contaminate food and agricultural products and impact consumers and farmers worldwide. Prevention and detection methods are utilized, but challenges persist, especially in developing countries without sufficient regulatory enforcement.
COMPREHENSIVE REVIEWS IN FOOD SCIENCE AND FOOD SAFETY
(2021)
Article
Green & Sustainable Science & Technology
Marsiale Kamugisha, Henry Mutembei, Thuita Thenya
Summary: This study aimed to assess the value of agroforestry and food security in the Isingiro District. The results showed that the value of agroforestry and food security in the study area is still low, with only 21% of households practicing agroforestry being food secure. It is crucial to understand the psychological and behavioral factors that hinder households from adopting agroforestry practices, and the government should invest in capacity building and land policy revisions to support households in strengthening their income base.
INTERNATIONAL JOURNAL OF SUSTAINABLE DEVELOPMENT AND WORLD ECOLOGY
(2022)
Review
Oncology
Ju Youn Kim, Feng He, Michael Karin
Summary: NASH and HCC, two liver diseases related to obesity, are influenced by cholesterol and metabolic regulators in their development.
Article
Environmental Sciences
Alex Saturday, Thomas J. Lyimo, John Machiwa, Siajali Pamba
Summary: The purpose of this study was to investigate the spatial and temporal variations of phytoplankton species composition and biomass in Lake Bunyonyi in Uganda. The study found that the lake contains a diverse range of phytoplankton species, with cyanobacteria and chlorophytes being the dominant groups. The presence of certain toxic cyanobacteria species poses potential challenges to water quality management. The unequal distribution of phytoplankton species in the lake and the high percentage of previously unreported species highlight the importance of regular monitoring and the establishment of a dedicated committee for water management.
ENVIRONMENTAL MONITORING AND ASSESSMENT
(2022)
Article
Infectious Diseases
James S. Miller, Palka Patel, Sara Mian-McCarthy, Andrew Christopher Wesuta, Michael Matte, Moses Ntaro, Shem Bwambale, Jessica Kenney, Geren S. Stone, Edgar Mugema Mulogo
Summary: The study in rural western Uganda found high overall community usage of and satisfaction with iCCM care for malaria, pneumonia, and diarrhea, with over half of respondents indicating they would seek iCCM care in the future and expressing confidence in the VHW's abilities.
Article
Infectious Diseases
Abel Wilson Walekhwa, Moses Ntaro, Peter Chris Kawungezi, Chiara Achangwa, Rabbison Muhindo, Emmanuel Baguma, Michael Matte, Richard Migisha, Raquel Reyes, Peyton Thompson, Ross M. Boyce, Edgar M. Mulogo
Summary: Measles outbreaks are still prevalent in sub-Saharan Africa, with low vaccination coverage identified as the main risk factor. The study in Bugoye, Uganda revealed a prolonged measles outbreak between December 2018 and October 2019, highlighting the importance of improving vaccination strategies.
BMC INFECTIOUS DISEASES
(2021)
Article
Immunology
Ross M. Boyce, Brandon D. Hollingsworth, Emma Baguma, Erin Xu, Varun Goel, Amanda Brown-Marusiak, Rabbison Muhindo, Raquel Reyes, Moses Ntaro, Mark J. Siedner, Sarah G. Staedke, Jonathan J. Juliano, Edgar M. Mulogo
Summary: Three rounds of chemoprevention with dihydroartemisinin-piperaquine delivered under pragmatic conditions reduced the incidence of malaria after severe flooding in western Uganda. These findings provide a proof-of-concept for the use of chemoprevention to reduce excess disease burden associated with severe flooding.
CLINICAL INFECTIOUS DISEASES
(2022)
Article
Infectious Diseases
Claire M. Cote, Varun Goel, Rabbison Muhindo, Emmanuel Baguma, Moses Ntaro, Bonnie E. Shook-Sa, Raquel Reyes, Sarah G. Staedke, Edgar M. Mulogo, Ross M. Boyce
Summary: The study found that LLIN use and sourcing were correlated with household elevation and estimated distance to the nearest health facility. Current facility-based distribution strategies appear to have limitations in reach. More frequent mass distribution campaigns and complementary approaches may be necessary to maintain universal LLIN coverage and high rates of use among children in rural Uganda.
Article
Medicine, General & Internal
Clark H. Cunningham, Christopher M. Hennelly, Jessica T. Lin, Ratawan Ubalee, Ross M. Boyce, Edgar M. Mulogo, Nicholas Hathaway, Kyaw L. Thwai, Fernandine Phanzu, Albert Kalonji, Kashamuka Mwandagalirwa, Antoinette Tshefu, Jonathan J. Juliano, Jonathan B. Parr
Summary: The novel SHERLOCK assays demonstrated high sensitivity and specificity in detecting various species of Plasmodium, making them valuable tools for malaria diagnosis and surveillance.
Article
Infectious Diseases
Patrick Lubogo, John Edward Lukyamuzi, Deo Kyambadde, Alex Aboda Komakech, Freddy Eric Kitutu, Edgar Mugema Mulogo
Summary: The study compared the cost-effectiveness of delivering iCCM interventions via drug sellers versus CHWs in rural Uganda, finding that while the drug seller model had higher costs, it also resulted in better outcomes, indicating it could complement the CHW intervention as a strategy to increase access to quality treatment.
Article
Infectious Diseases
Ross M. Boyce, Enid Muhindo, Emmanuel Baguma, Rabbison Muhindo, Bwambale Shem, Ruthly Francois, Sam Hawke, Bonnie E. Shook-Sa, Moses Ntaro, Aisha Nalusaji, Dan Nyehangane, Raquel Reyes, Jonathan J. Juliano, Mark J. Siedner, Sarah G. Staedke, Edgar M. Mulogo
Summary: This study investigated the safety and efficacy of using permethrin-treated baby wraps to prevent malaria infection. The results showed that permethrin-treated baby wraps were well-tolerated and widely accepted. This study provides support for future trials in this area.
Article
Water Resources
Abel Wilson Walekhwa, Moses Ntaro, Peter Kawungezi, Evas Nimusiima, Chiara Achangwa, David Musoke, Edgar Mugema Mulogo
Summary: Billions of people worldwide, especially in sub-Saharan Africa, still do not have access to safe water. A study conducted in Kibuku district, Eastern Uganda analyzed the water quality of improved water sources and identified factors associated with it. The findings revealed that the majority of water sources had poor water quality, which was attributed to agricultural activities, dirty water collection containers, and a negative attitude towards water chlorination.
SUSTAINABLE WATER RESOURCES MANAGEMENT
(2022)
Article
Public, Environmental & Occupational Health
Moses Ntaro, Judith Owokuhaisa, John Bosco Isunju, Edgar Mulogo, John C. Ssempebwa
Summary: This study explored the perceived factors influencing the Open Defecation Free (ODF) status in rural South Western Uganda. Contextual factors such as farming activities far from home, financial constraints, rainy seasons, collapsible soft soils, and alcohol use, as well as psychological factors such as perceived health risk, low perceived severity, negative attitudes, and time wastage, were found to influence the ODF status.
Article
Medicine, General & Internal
James S. Miller, Edgar Mugema Mulogo, Andrew Christopher Wesuta, Nobert Mumbere, Jackson Mbaju, Michael Matte, Moses Ntaro, Daniel A. Guiles, Palka R. Patel, Shem Bwambale, Jessica Kenney, Raquel Reyes, Geren S. Stone
Summary: The study assessed the ability of volunteer village health workers in Uganda to provide integrated community case management (iCCM) care for children under 5 years old. The study found that overall, the quality of care provided by the village health workers was relatively constant over time, with a trend towards decreasing quality after 3 years of providing iCCM care.
Article
Infectious Diseases
Abel Wilson Walekhwa, David Musoke, Aisha Nalugya, Claire Biribawa, Godfrey Nsereko, Solomon Tsebeni Wafula, Brenda Nakazibwe, Mary Nantongo, Doreen Awino Odera, Achangwa Chiara, Ross Mathew Boyce, Edgar Mugema Mulogo
Summary: Barriers to measles vaccination identified in this study were related to supply and stock management, health worker attitudes and workload, financing of vaccination outreach activities, scheduling of health workers, community beliefs, and accessibility of healthcare facilities. These logistical and cultural barriers highlight the need for more efficient supply management practices and resourcing of immunization efforts to achieve Ministry of Health targets in Uganda.
BMC INFECTIOUS DISEASES
(2022)
Article
Infectious Diseases
Fred Bagenda, Andrew Christopher Wesuta, Geren Stone, Moses Ntaro, Palka Patel, Jessica Kenney, Stephen Baguma, David Santson Ayebare, Shem Bwambale, Michael Matte, Peter Chris Kawungezi, Edgar Mugema Mulogo
Summary: Community Health Workers in rural Uganda play a significant role in managing the three most common illnesses among children under 5 years old. The trend is shifting from malaria to pneumonia as the most common illness. Children under 1 year old are at higher risk of getting pneumonia and diarrhoea, and lower risk of getting malaria.
Article
Obstetrics & Gynecology
Hamson Kanyesigye, Jerome Kabakyenga, Edgar Mulogo, Yarine Fajardo, Daniel Atwine, Noni E. MacDonald, Robert Bortolussi, Richard Migisha, Joseph Ngonzi
Summary: Giving a phone call prior to referral of mothers in labour can reduce preparation delays and improve maternal-fetal outcomes at a referral hospital, especially in resource limited settings.
BMC PREGNANCY AND CHILDBIRTH
(2022)
Article
Health Care Sciences & Services
Hamson Kanyesigye, Joseph Ngonzi, Edgar Mulogo, Yarine Fajardo, Jerome Kabakyenga
Summary: This study described the profile of emergency obstetric referrals, challenges faced in the implementation process, and self-reported solutions by health workers. Most referrals were from people of poor social-economic status, who used taxis and lacked professional-escort. Health workers reported harassment, communication gaps, and shortages of supplies. The use of mobile phone technology was suggested as a potential solution to bridge the communication gap.
RISK MANAGEMENT AND HEALTHCARE POLICY
(2022)
Article
Medicine, General & Internal
Aitana Juan-Giner, Derick Kimathi, Kyra H. Grantz, Mainga Hamaluba, Patrick Kazooba, Patricia Njuguna, Gamou Fall, Moussa Dia, Ndeye S. Bob, Thomas P. Monath, Alan D. Barrett, Joachim Hombach, Edgar M. Mulogo, Immaculate Ampeire, Henry K. Karanja, Dan Nyehangane, Juliet Mwanga-Amumpaire, Derek A. T. Cummings, Philip Bejon, George M. Warimwe, Rebecca F. Grais
Summary: This study assessed the immunogenicity and safety of fractional doses of four yellow fever vaccines compared to standard doses. The results showed that fractional doses from all vaccines were non-inferior to the standard dose, with no major safety concerns. This supports the use of fractional dosage in the general adult population for outbreak response in situations of vaccine shortage.
