Review
Oncology
Fiona S. M. Schulte, Michaela Patton, Nicole M. Alberts, Alicia Kunin-Batson, Barbara A. Olson-Bullis, Caitlin Forbes, K. Brooke Russell, Alexandra Neville, Lauren C. Heathcote, Cynthia W. Karlson, Nicole M. Racine, Courtney Charnock, Matthew C. Hocking, Pia Banerjee, Perri R. Tutelman, Melanie Noel, Kevin R. Krull
Summary: Survivors of childhood cancer are at higher risk of experiencing pain, especially chronic pain. Females report more pain than males, and factors related to pain will require stronger evidence support. Theoretically grounded, multidimensional measurements of pain are absent from the literature.
Article
Oncology
Danique W. W. Bos-van den Hoek, Marrit A. Tuinman, Marij A. Hillen, Fiorella L. Huijgens, Elisabeth Kurpershoek, Gabriele Calaminus, Peter Kaatsch, Mariet Hagedoorn, Vicky Lehmann
Summary: The objective of this study was to understand how young adult childhood cancer survivors disclose their cancer history to romantic partners and the impact of such disclosures on relationship satisfaction. The findings showed that around half of the survivors always disclosed their cancer history to their partners and identified several factors influencing disclosure, such as survivors' attitudes, integration of cancer into their identity, and anticipated effects on romantic relationships. Additionally, some survivors experienced difficulties in disclosing their cancer history, especially if they had negative experiences in the past. Overall, survivors were satisfied with their relationship status, with partnered survivors reporting greater satisfaction than singles, especially if they had positive responses from their partners.
Article
Oncology
Chelsea J. Siwik, Kinnari Jhaveri, Jamie Alexis Cohen, Mikela Barulich, Alison Chang, Anna O. Levin, Neha G. Goyal, Michelle Melisko, Margaret A. Chesney, Dianne Shumay
Summary: This study evaluated the acceptability and preliminary outcomes of a group intervention called Survivorship Wellness Group Program (SWGP) in cancer centers. The results showed that SWGP is an acceptable and replicable model that can improve quality of life, reduce mental health symptoms, and increase knowledge in multiple domains of wellness for cancer survivors.
SUPPORTIVE CARE IN CANCER
(2023)
Article
Oncology
Edward Christopher Dee, Ryan D. Nipp, Vinayak Muralidhar, Zizi Yu, Santino S. Butler, Brandon A. Mahal, Paul L. Nguyen, Nina N. Sanford
Summary: A majority of cancer survivors reported financial worry, with female sex, younger age, and Asian American race associated with increased odds of financial worry. Participants endorsing financial worry were more likely to have psychological distress.
SUPPORTIVE CARE IN CANCER
(2021)
Article
Oncology
Patrick Boyd, Ashley B. Murray, Travis Hyams, Alix G. Sleight, Richard P. Moser, Jamie Arndt, Susan M. Czajkowski, Kara Hall
Summary: The study found that high neuroticism in cancer survivors is associated with physician avoidance and physician visit concerns when treatment has a temporal distance. By decoupling the association between cancer and death, interventions can help increase the willingness of cancer survivors to seek cancer care follow-ups and healthcare more generally.
Article
Oncology
Anna M. Jones, Emily K. Browne, Kristen Adams, Brian S. Potter, Valerie McLaughlin Crabtree, Niki Jurbergs, R. Elyse Heidelberg, Rachel Tillery Webster
Summary: This study examined the role of transition-focused psychology appointments in preparing families for the transition off therapy. The results showed that caregivers experienced distress during the transition, but those who had received psychology consultations and cognitive assessments felt more informed and prepared, leading to decreased distress.
Review
Oncology
Louise Mullen, Christina Signorelli, Larissa Nekhlyudov, Paul B. Jacobsen, Isaiah Gitonga, Tania Estape, Beverly Lim-Hoeg, Anne Miles, Cristina Sade, Carolyn Mazariego, Csaba L. Degi, Fuchsia Howard, Sharon Manne, Luzia Travado, Michael Jefford
Summary: This study found that most National Cancer Control Plans did not mention psycho-oncology, and only one-quarter of the plans had clear objectives specifically in the post-treatment survivorship phase.
Article
Psychiatry
Mareike Ernst, Antonia M. Werner, Elmar Brahler, Philipp S. Wild, Jorg Faber, Hiltrud Merzenich, Manfred E. Beutel
Summary: The aim of this study was to evaluate a short scale for assessing posttraumatic growth in cancer survivors. Using data from 633 childhood cancer survivors, the researchers found that the short scale had good reliability and validity and was associated with various cancer-related and psychological variables.
JOURNAL OF PSYCHOSOMATIC RESEARCH
(2023)
Article
Oncology
Sungkeun Shim, Danbee Kang, Ka Ryeong Bae, Woo Yong Lee, Seok Jin Nam, Tae Sung Sohn, Byong Chang Jeong, Dong Hyun Sinn, Sun Seog Kweon, Young Mog Shim, Juhee Cho
Summary: This study aimed to quantify the association between cancer stigma and job loss among cancer survivors. The results showed that survivors with cancer stigma, particularly regarding the impossibility of recovery and stereotypes, were more likely to lose their jobs. Comprehensive interventions and public campaigns against cancer stigma would be necessary to address the social and economic impact of job loss among working cancer survivors.
Article
Oncology
Soleil Chahine, Gordon Walsh, Robin Urquhart
Summary: This study identifies anxiety, fear, depression, and changes in sexual intimacy as major concerns for cancer survivors. Sociodemographic factors, healthcare provider access, and follow-up care impact the degree to which survivors' needs are met.
Article
Oncology
Jessica Molinaro, Anjishnu Banerjee, Stanley Lyndon, Sarah Slocum, Carrie Danhieux-Poole, Christine Restivo-Pritzl, Ann Marie Uselmann, Lyndsey Wallace, Jennifer M. Knight
Summary: The study examined the impact of outpatient psycho-oncology treatment on distress and depression in cancer patients. Results showed significant reductions in distress and depression scores after the psycho-oncology visits, with patients no longer meeting criteria for clinically significant distress and depression. The findings support the use of psycho-oncology services in cancer patients throughout survivorship.
Article
Oncology
K. Y. Ho, Katherine K. W. Lam, W. Xia, S. Y. Chiu, Godfrey C. F. Chan
Summary: This study provides information on the prevalence and severity of sleep disruption among Hong Kong Chinese childhood cancer survivors. It identifies factors influencing sleep disruption and highlights the importance of physical activity in reducing sleep disturbance.
Article
Oncology
Jacqueline H. Becker, Charlotte Ezratty, Nusrat Jahan, Mita Goel, Yael Tobi Harris, Jenny J. Lin
Summary: Breast cancer survivors with cognitive impairment tend to rely more on external sources of motivation to perform health behaviors, regardless of depression. Future studies and interventions should consider screening for cognitive impairment and involving caregivers to improve outcomes.
Article
Oncology
Claire Gore, Karolina Lisy, Clare O'Callaghan, Colin Wood, Jon Emery, Andrew Martin, Richard De Abreu Lourenco, Penelope Schofield, Michael Jefford
Summary: This study explored patient experiences with shared and telehealth-based survivorship care. Findings can guide the implementation of these models, particularly around care coordination, communication, preparation, and personalised pathways of care.
Review
Oncology
Elizabeth K. Arthur, Jennifer Bissram, Kaitlyn Rechenberg, Annie Wills, Katie Campanelli, Usha Menon, Timiya S. Nolan
Summary: This systematic review summarizes contemporary literature on the sexual wellbeing experiences of women of color (WOC) treated for cancer. The findings reveal that WOC experience changes in sexual health and intimacy after cancer treatment, and these experiences are often shaped by sociocultural factors.
Article
Immunology
Rosie Shrout, Annelise A. Madison, Megan E. Renna, Catherine M. Alfano, Stephen P. Povoski, Adele M. Lipari, Doreen M. Agnese, William E. Carson, William B. Malarkey, Michael T. Bailey, Janice K. Kiecolt-Glaser
Summary: Satisfying relationships among breast cancer survivors are associated with lower gut permeability and inflammation levels, leading to improved physiological health. This type of relationship can help reduce disease risks and enhance quality of life.
BRAIN BEHAVIOR AND IMMUNITY
(2022)
Article
Endocrinology & Metabolism
Megan E. Renna, M. Rosie Shrout, Annelise A. Madison, Jeanette M. Bennett, William B. Malarkey, Charles F. Emery, Janice K. Kiecolt-Glaser
Summary: Breast cancer survivors with a distress disorder history have lower HRV during and after an experimental stressor, and experience higher levels of anxiety compared to those without such a history.
PSYCHONEUROENDOCRINOLOGY
(2022)
Article
Psychology, Multidisciplinary
Annelise A. Madison, Rebecca Andridge, M. Rosie Shrout, Megan E. Renna, Jeanette M. Bennett, Lisa M. Jaremka, Christopher P. Fagundes, Martha A. Belury, William B. Malarkey, Janice K. Kiecolt-Glaser
Summary: The social-signal-transduction theory of depression suggests that individuals who experience ongoing interpersonal stress and have a greater inflammatory response to social stressors are more likely to develop depression. This was confirmed in two adult samples, where heightened depressive symptoms were observed in those with more frequent interpersonal tension and greater inflammatory reactivity to social stress. Lonelier and less socially supported individuals, particularly those with higher inflammatory response to social-evaluative stressors, showed increased depressive symptoms.
PSYCHOLOGICAL SCIENCE
(2022)
Article
Communication
Stephanie J. Wilson, Lisa M. Jaremka, Christopher P. Fagundes, Rebecca Andridge, Janice K. Kiecolt-Glaser
Summary: Research shows that the use of "we" in couples' discussions can predict better relationship quality and well-being. However, prior studies have not differentiated "we" talk based on its context. Additionally, the consistency of "we" talk during conflicts is high, but its effects may vary depending on the context in which it is used.
JOURNAL OF SOCIAL AND PERSONAL RELATIONSHIPS
(2022)
Article
Immunology
Janice K. Kiecolt-Glaser, Megan Renna, Juan Peng, John Sheridan, Maryam Lustberg, Bhuvaneswari Ramaswamy, Robert Wesolowski, Jeffrey B. VanDeusen, Nicole O. Williams, Sagar D. Sardesai, Anne M. Noonan, Raquel E. Reinbolt, Daniel G. Stover, Mathew A. Cherian, William B. Malarkey, Rebecca Andridge
Summary: This study investigated the inflammatory responses of breast cancer survivors to a typhoid vaccine as an indicator of their innate immune response to new pathogens. The results showed that chemotherapy and central obesity were associated with smaller vaccine responses. Women with lower fitness levels also had reduced vaccine responses.
BRAIN BEHAVIOR AND IMMUNITY
(2022)
Article
Geriatrics & Gerontology
Stephanie J. Wilson, Janice K. Kiecolt-Glaser
Summary: This study compares the differences in language use and emotional reactions during relationship history discussions between older and younger couples. The study found that compared to younger couples, older couples used more positive words and less immediacy during the discussion, which was associated with less negative mood and more positive appraisals among husbands. However, partners' language use in older couples was more similar but unrelated to mood and appraisals.
JOURNALS OF GERONTOLOGY SERIES B-PSYCHOLOGICAL SCIENCES AND SOCIAL SCIENCES
(2022)
Article
Oncology
Megan E. Renna, M. Rosie Shrout, Annelise A. Madison, Catherine M. Alfano, Stephen P. Povoski, Adele M. Lipari, William E. Carson, William B. Malarkey, Janice K. Kiecolt-Glaser
Summary: This study found that colorectal cancer patients with higher levels of depressive and anxiety symptoms experienced greater pain, fatigue, and inflammation. These results emphasize the negative impact that anxiety and depression can have on the physical and biological side effects of colorectal cancer.
Article
Endocrinology & Metabolism
Annelise A. Madison, Janice K. Kiecolt-Glaser
Summary: This article assesses the relationship between inflammation and impulsivity and presents three challenges: vague definition of impulsivity, reverse causality, and lack of causal evidence. Future research can explore the relationship between inflammation and impulsivity by improving study design.
PSYCHONEUROENDOCRINOLOGY
(2022)
Article
Geriatrics & Gerontology
Ruchika Shaurya Prakash, Stephanie Fountain-Zaragoza, Megan Fisher, Oyetunde Gbadeyan, Rebecca Andridge, Janice Kiecolt-Glaser, Heena R. Manglani, Elizabeth J. Duraney, Anita Shankar, Michael R. McKenna, James Teng, Madhura Phansikar, Rosie Canter
Summary: This study aims to examine the benefits of a manualized mindfulness-based stress reduction program in improving attentional control and reducing mind-wandering in older adults. The study design includes randomized controlled trial with behavioral and neuroimaging assessments, as well as long-term follow-up. The primary outcomes are behavioral measures of attentional control and mind-wandering.
Article
Psychology, Clinical
Megan E. Renna, M. Rosie Shrout, Annelise A. Madison, Maryam Lustberg, Stephen P. Povoski, Doreen M. Agnese, Raquel E. Reinbolt, Robert Wesolowski, Nicole O. Williams, Bhuvaneswari Ramaswamy, Sagar D. Sardesai, Anne M. Noonan, Jeffrey B. VanDeusen, Daniel G. Stover, Mathew Cherian, William B. Malarkey, Michael Di Gregorio, Janice K. Kiecolt-Glaser
Summary: Psychological disorders can worsen physical symptoms associated with breast cancer diagnosis and treatment, and a distress disorder history may increase the risk of pain, fatigue, sleep difficulties, and lower self-rated health in breast cancer survivors both before and after adjuvant treatment.
INTERNATIONAL JOURNAL OF BEHAVIORAL MEDICINE
(2023)
Article
Immunology
Annelise A. Madison, Baldwin Way, Kyle G. Ratner, Megan Renna, Rebecca Andridge, Juan Peng, M. Rosie Shrout, John Sheridan, Maryam Lustberg, Bhuvaneswari Ramaswamy, Robert Wesolowski, Jeffrey B. VanDeusen, Nicole O. Williams, Sagar D. Sardesai, Anne M. Noonan, Raquel E. Reinbolt, Daniel G. Stover, Mathew A. Cherian, William B. Malarkey, Janice K. Kiecolt-Glaser
Summary: This study examined whether a typhoid vaccine would increase social disconnection and avoidance behavior, and found that mild inflammatory stimuli did not affect social processes.
BRAIN BEHAVIOR AND IMMUNITY
(2023)
Meeting Abstract
Psychiatry
Marie Filatov, Annelise Madison, William Malarkey, Janice Kiecolt-Glaser
PSYCHOSOMATIC MEDICINE
(2022)
Meeting Abstract
Psychiatry
Annelise A. Madison, Janice K. Kiecolt-Glaser, William Malarkey
PSYCHOSOMATIC MEDICINE
(2022)
Meeting Abstract
Psychiatry
Megan E. Renna, Rosie Shrout, Annelise A. Madison, Janice K. Kiecolt-Glaser
PSYCHOSOMATIC MEDICINE
(2022)
Meeting Abstract
Psychiatry
M. Rosie Shrout, Annelise Madison, Megan E. Renna, Janice E. Kiecolt-Glaser
PSYCHOSOMATIC MEDICINE
(2022)
Article
Oncology
Diego de Miguel-Perez, Edward M. Pickering, Umberto Malapelle, William Grier, Francesco Pepe, Pasquale Pisapia, Gianluca Russo, Joseph A. Pinto, Alessandro Russo, Giancarlo Troncone, Melissa J. Culligan, Katherine A. Scilla, Ranee Mehra, Pranshu Mohindra, Oscar Arrieta, Andres F. Cardona, Marzia Del Re, Ashutosh Sachdeva, Fred R. Hirsch, Andrea Wolf, Joseph S. Friedberg, Christian Rolfo
Summary: In this study, genetic alterations in resectable pleural mesothelioma tissues and blood samples were analyzed, and it was found that high tissue tumor mutational burden, tissue median minor allele frequency, blood tumor mutational burden, and specific mutations were correlated with outcomes in patients with resected PM. These findings suggest that molecular profiling could help identify longer survivors in patients with resected PM.
EUROPEAN JOURNAL OF CANCER
(2024)
Article
Oncology
Davide Melisi, Camilla Zecchetto, Valeria Merz, Giuseppe Malleo, Luca Landoni, Alberto Quinzii, Simona Casalino, Federica Fazzini, Marina Gaule, Camilla Pesoni, Luca Casetti, Alessandro Esposito, Giovanni Marchegiani, Cristiana Piazzola, Mirko D'Onofrio, Riccardo de Robertis, Armando Gabbrielli, Laura Bernardoni, Stefano F. Crino, Silvia Pietrobono, Claudio Luchini, Camillo Aliberti, Guido Martignoni, Stefano Milleri, Giovanni Butturini, Aldo Scarpa, Roberto Salvia, Claudio Bassi
Summary: This study evaluated the safety and activity of liposomal irinotecan in the perioperative treatment of resectable pancreatic ductal adenocarcinoma (rPDAC) patients. The results showed that NALIRIFOX has manageable and active outcomes, and should be further investigated in randomized trials comparing it to standard upfront surgery followed by adjuvant therapy.
EUROPEAN JOURNAL OF CANCER
(2024)
Article
Oncology
Eric Jonasch, Todd M. Bauer, Kyriakos P. Papadopoulos, Elizabeth R. Plimack, Jaime R. Merchan, David F. Mcdermott, M. Dror Michaelson, Leonard J. Appleman, Ananya Roy, Rodolfo F. Perini, Yanfang Liu, Toni K. Choueiri
Summary: After a median follow-up of 41.2 months, belzutifan monotherapy demonstrated durable antitumor activity in patients with advanced ccRCC and acceptable safety.
EUROPEAN JOURNAL OF CANCER
(2024)
Article
Oncology
Patricia A. H. Hamers, Geraldine R. Vink, Marloes A. G. Elferink, Leon M. G. Moons, Cornelis J. A. Punt, Anne M. May, Miriam Koopman
Summary: Screen-detection of the primary tumor is associated with longer overall survival after metachronous metastasis.
EUROPEAN JOURNAL OF CANCER
(2024)
Article
Oncology
Camilla Nero, Nicolo Bizzarri, Stefano Di Berardino, Francesca Sillano, Giuseppe Vizzielli, Francesco Cosentino, Virginia Vargiu, Pierandrea De Iaco, Anna Myriam Perrone, Enrico Vizza, Benito Chiofalo, Stefano Uccella, Fabio Ghezzi, Luigi Carlo Turco, Giacomo Corrado, Diana Giannarelli, Tina Pasciuto, Gian Franco Zannoni, Anna Fagotti, Giovanni Scambia
Summary: This study evaluates the sensitivity and specificity of sentinel-lymph-node mapping compared to systematic lymphadenectomy in detecting lymph node metastasis in early stage ovarian cancer. The results show that sentinel-lymph-node mapping did not reach the expected sensitivity, but ultra-staging protocol improved the accuracy of diagnosis for patients.
EUROPEAN JOURNAL OF CANCER
(2024)
Article
Oncology
Adriana Hepner, Judith M. Versluis, Roslyn Wallace, Clara Allayous, Lauren Julia Brown, Claudia Trojanielloh, Camille Lea Gerardi, Yanina J. L. Jansenj, Prachi Bhave, Bart Neyns, Andrew Haydon, Olivier Michielin, Joanna Manganan Oliver Klein, Alexander N. Shoushtari, Allison Betof Warner, Paolo Antonio Ascierto, Jennifer Leigh McQuade, Matteo S. Carlino, Lisa Zimmer, Celeste Lebbe, Douglas B. Johnson, Shahneen Sandhu, Victoria Atkinson, Christian U. Blank, Serigne N. Lo, Georgina V. Long, Alexander M. Menzies
Summary: Acquired resistance to PD-1 therapy in melanoma is mainly oligometastatic, and patients may have a favorable survival outcome following salvage treatment.
EUROPEAN JOURNAL OF CANCER
(2024)
Article
Oncology
Savannah Roy, Stephanie Lakritz, Anna R. Schreiber, Elizabeth Molina Kuna, Cathy J. Bradley, Lavanya Kondapalli, Jennifer R. Diamond
Summary: This study evaluates major adverse cardiovascular events (MACE) in older women with TNBC treated with anthracycline and taxane-based chemotherapy (ATAX) compared to taxane-based chemotherapy (TAX). The results show that ATAX does not increase the risk of MACE and there is no difference in survival between patients who received TAX and ATAX.
EUROPEAN JOURNAL OF CANCER
(2024)
Letter
Oncology
Pei-Chun Weng, Yau-Li Huang, Chun-Yu Cheng
EUROPEAN JOURNAL OF CANCER
(2024)
Article
Oncology
Philipp Jansen, Jean Le 'Clerc Arrastia, Daniel Otero Baguer, Maximilian Schmidt, Jennifer Landsberg, Joerg Wenzel, Michael Emberger, Dirk Schadendorf, Eva Hadaschik, Peter Maass, Klaus Georg Griewank
Summary: This study highlights the enormous potential of artificial intelligence in pathology, showing that it can aid in the identification of rare cutaneous adnexal tumors and potentially become a standard tool in routine diagnostics.
EUROPEAN JOURNAL OF CANCER
(2024)
Article
Oncology
Casper W. F. van Eijck, Gaby Strijk, Eveline E. Vietscha, Fleur van der Sijde, Maaike Verheij, Dana A. M. Mustafa, Madelief Vinkc, Joachim G. J. V. Aerts, Casper H. J. van Eijck, Marcella Willemsen
Summary: The study reveals that FOLFIRINOX has immunomodulatory effects, suggesting its potential in immune-based combination therapies for pancreatic cancer. Additionally, certain plasma proteins hold promise as circulating predictive biomarkers for early prediction of FOLFIRINOX response in patients with pancreatic cancer.
EUROPEAN JOURNAL OF CANCER
(2024)
Article
Oncology
Marwan Fakih, Chongkai Wang, Jaideep Sandhu, Jian Ye, Colt Egelston, Xiaochen Li
Summary: This study explores the impact of metastatic sites on treatment outcomes for chemotherapy-refractory colorectal cancer patients. It found that patients with liver or peritoneal metastases had poor treatment outcomes, while those with lung-only metastases showed significant response. The presence of concurrent lymph node or other extrahepatic metastatic disease diminished treatment response in patients with lung metastases. Future checkpoint inhibitor trials should stratify patients based on metastatic locations.
EUROPEAN JOURNAL OF CANCER
(2024)
Article
Oncology
Georgios Christos Tsiatsianis, Candace S. Y. Chan, Ioannis Mouratidis, Nikol Chantzi, Anna Maria Tsiatsiani, Nelson S. Yee, Apostolos Zaravinos, Verena Kantere, Ilias Georgakopoulos-Soares
Summary: The study reveals that nullpeptides can serve as biomarkers for cancer detection and treatment, particularly in highly recurrent cancer patients. These nullpeptides primarily occur in highly expressed genes, particularly in specific loci of oncogenes and tumor suppressors. Recurrent nullpeptides are more likely to be found in neoantigens, which play a significant role in immunotherapy.
EUROPEAN JOURNAL OF CANCER
(2024)