Article
Oncology
Anke Smits, Claire-Marie Agius, Dominic Blake, Christine Ang, Ali Kucukmetin, Maaike van Ham, Johanna M. A. Pijnenborg, Joanne Knight, Stuart Rundle
Summary: This study aimed to assess the value of cardiopulmonary exercise testing (CPET) in predicting surgical complications in ovarian cancer surgery. The results showed that patients with a raised VE/VCO2 during CPET experienced more surgical complications. However, there was no relationship found with other outcomes such as hospital stay, readmission, and resectability of disease.
Article
Anesthesiology
Vladimir Bolshinsky, Hilmy Ismail, Michael Li, Jarrod Basto, Robert Schier, Anna Hagemeier, Kwok-Ming Ho, Alexander Heriot, Bernhard Riedel
Summary: This pilot study explores the impact of preoperative covariates and traditional cardiopulmonary exercise testing (CPET)-derived parameters on postoperative outcomes after major colorectal cancer surgery. The study found that low preoperative haemoglobin, low albumin, or high neutrophil count were associated with postoperative complications and reduced overall survival. Gas exchange parameters focusing on VCO2 kinetics and correcting peakVO2 to body surface area could improve CPET-derived preoperative risk assessment. Inflammatory parameters also added significant predictive value to preoperative risk assessment.
PERIOPERATIVE MEDICINE
(2022)
Article
Cardiac & Cardiovascular Systems
Jessica Zannoni, Marco Guazzi, Valentina Milani, Francesco Bandera, Eleonora Alfonzetti, Ross Arena
Summary: Cardiorespiratory fitness is important and can be assessed through cardiopulmonary exercise testing. Peak oxygen consumption and minute ventilation/carbon dioxide production slope are key measures. Further research is needed to understand the role of this assessment in primary care.
INTERNATIONAL JOURNAL OF CARDIOLOGY
(2023)
Article
Medicine, General & Internal
Massimiliano Greco, Alessandra Angelucci, Gaia Avidano, Giovanni Marelli, Stefano Canali, Romina Aceto, Marta Lubian, Paolo Oliva, Federico Piccioni, Andrea Aliverti, Maurizio Cecconi
Summary: Wearable devices are being evaluated as tools for preoperative assessment to improve patient outcomes. This study found a strong association between 6MWT, preoperative scales, and data from wearable devices. These findings suggest that low-cost wearable devices have potential as a tool for evaluating cardiopulmonary fitness.
Review
Physiology
Maria F. Ionescu, Sethu Mani-Babu, Luiza H. Degani-Costa, Martin Johnson, Chelliah Paramasivan, Karl Sylvester, Jonathan Fuld
Summary: Dysfunctional breathing (DB) is a condition that affects individuals in various situations, including athletes, and can be diagnosed and managed using cardiopulmonary exercise testing (CPET). Proper recognition of DB is important for treatment and can lead to significant benefits for individuals.
FRONTIERS IN PHYSIOLOGY
(2021)
Article
Multidisciplinary Sciences
Amanda Hall, Andrea Pike, Andrea Patey, Sameh Mortazhejri, Samantha Inwood, Shannon Ruzycki, Kyle Kirkham, Krista Mahoney, Jeremy Grimshaw
Summary: This study investigated the perceived barriers and enablers to reducing unnecessary preoperative tests for low-risk surgical procedures in Newfoundland, Canada. The results showed that uncertainty about responsibility, inability to access patient records or consult/communicate with colleagues, worry about surgery delays/cancellation, workplace norms conflicting with guidelines, concerns about missing something serious or litigation were factors influencing test ordering behavior. Clear institutional guidelines, improved communication, and periodic evaluation were identified as enablers to reduce unnecessary preoperative testing.
Article
Otorhinolaryngology
Hans Rudolf Briner, Andreas Leunig, Christoph Schlegel, Daniel Simmen
Summary: This study analyzed the effectiveness of a risk assessment scoring system for determining eligibility for day surgery, taking into account medical, procedure-related, and socioeconomic factors. The results showed that the day surgery risk score may not be more accurate than a random classification model in predicting postoperative complications after endoscopic sinus surgery.
EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY
(2021)
Article
Critical Care Medicine
Lindsay M. Forbes, Todd M. Bull, Tim Lahm, Barry J. Make, William K. Cornwell III
Summary: Right ventricular dysfunction in pulmonary hypertension has negative implications for exercise capacity, morbidity, and mortality. During exercise, right ventricular afterload may increase disproportionately, impairing right ventricular contractility and limiting cardiac output. Abnormal pulmonary vascular response to exercise can signal early disease and increased mortality. Exercise testing can evaluate pulmonary vascular response and right ventricular contractile reserve. More research is needed to determine the role of exercise stress testing in the management of pulmonary vascular disease.
Article
Anesthesiology
James O. M. Plumb, James M. Otto, Shriya B. Kumar, Sitara Bali, Mai Wakatsuki, Walter F. J. Schmidt, Hugh E. Montgomery, Michael P. W. Grocott, Denny Z. Levett
Summary: Intravenous iron treatment for iron-deficient anemic patients prior to surgery can increase hemoglobin levels, total hemoglobin mass, and exercise capacity. However, further research is needed to determine if these improvements can reduce perioperative morbidity.
PERIOPERATIVE MEDICINE
(2023)
Article
Surgery
Don Milliken, Martin Rooms, S. Ramani Moonesinghe, Shaman Jhanji
Summary: The study found that peak power output (PPO) test can be used to predict abnormal cardiopulmonary exercise testing (CPET) results and assess the risk of adverse postoperative outcomes. The PPO test could serve as a tool for preoperative screening and risk stratification.
BRITISH JOURNAL OF SURGERY
(2022)
Article
Surgery
Riccardo Orlandi, Rocco Francesco Rinaldo, Alessandra Mazzucco, Andrea Baccelli, Michele Mondoni, Francesca Marchetti, Mariapia Zagaria, Jacopo Cefalo, Andrea Leporati, Matteo Montoli, Giorgio Ghilardi, Alessandro Baisi, Stefano Centanni
Summary: The study aims to evaluate postoperative outcomes of low-risk patients and compare them with patients without pulmonary impairment.
FRONTIERS IN SURGERY
(2023)
Article
Medicine, General & Internal
George A. Rose, Richard G. Davies, Jared Torkington, Ronan M. G. Berg, Ian R. Appadurai, David C. Poole, Damian M. Bailey
Summary: The impact of sex-related differences in cardiorespiratory fitness on postoperative patient mortality and surgical risk stratification was examined in this study. Lower cardiorespiratory fitness accounted for more deaths than traditional cardiovascular disease risk factors. Females had lower fitness levels but comparable mortality to males. Reevaluation of sex-specific fitness thresholds led to better stratification of female patients and improved surgical risk assessment.
EUROPEAN JOURNAL OF CLINICAL INVESTIGATION
(2023)
Article
Surgery
Sarah M. Kling, George A. Taylor, Matthew M. Philp, Juan Lucas Poggio, Howard M. Ross, Lindsay E. Kuo
Summary: In patients undergoing elective anorectal surgery, over half receive preoperative laboratory testing (PLT).
There was no difference in postoperative complication rates between patients who did or did not receive testing, indicating a need for more judicious use of PLT in this population.
JOURNAL OF SURGICAL RESEARCH
(2022)
Article
Oncology
Kotaro Yamashita, Makoto Yamasaki, Tomoki Makino, Koji Tanaka, Takuro Saito, Kazuyoshi Yamamoto, Tsuyoshi Takahashi, Yukinori Kurokawa, Yukiko Yasunobe, Hiroshi Akasaka, Hiromi Rakugi, Kiyokazu Nakajima, Hidetoshi Eguchi, Yuichiro Doki
Summary: Preoperative comprehensive geriatric assessment (CGA) is associated with the risk of postoperative complications in older patients with esophageal cancer. Patients in the frail group have a higher incidence of postoperative complications, longer hospitalization time, and lower survival rate.
ANNALS OF SURGICAL ONCOLOGY
(2023)
Article
Medicine, General & Internal
Kyosuke Imashiro, Yasuko Nishioka, Kenzo Teramura, Hiromi Hashimoto, Hiroki Kimura, Naoya Tanabe, Yasuhiro Taniguchi, Koya Nakai, Yasunori Umemoto, Tomoyuki Ito, Fumihiro Tajima, Yasuo Mikami
Summary: This study compared the peak oxygen uptake between cycle ergometer exercise testing and sitting exercise testing, and found that the peak oxygen uptake was lower in sitting exercise testing, but it had a strong correlation with cycle ergometer exercise testing, suggesting its suitability as a submaximal exercise test.
JOURNAL OF CLINICAL MEDICINE
(2023)
Review
Anesthesiology
T. E. F. Abbott, A. J. Fowler, P. Pelosi, M. Gama de Abreu, A. M. Moller, J. Canet, B. Creagh-Brown, M. Mythen, T. Gin, M. M. Lalu, E. Futier, M. P. Grocott, M. J. Schultz, R. M. Pearse
BRITISH JOURNAL OF ANAESTHESIA
(2018)
Review
Anesthesiology
D. J. Buggy, J. Freeman, M. Z. Johnson, K. Leslie, B. Riedel, D. I. Sessler, A. Kurz, V. Gottumukkala, T. Short, N. Pace, P. M. Myles
BRITISH JOURNAL OF ANAESTHESIA
(2018)
Article
Anesthesiology
S. J. Howell, S. E. Hoeks, R. M. West, S. B. Wheatcroft, A. Hoeft, Brigitte Leva, Benoit Plichon, Sandrine Damster, Mona Momeni, Christine Watremez, David Kahn, Anne-Sophie Dincq, Andre Danila, Maria Wittmann, Rafael Struck, Torben Rueddel, Florian Kessler, Stefan Rasche, Paraskevi Matsota, Antigona Hasani, Jurate Gudaityte, Aurika Karbonskiene, Rita Ferreira, Susana Carvalho, Dana Tomescu, Cristina Martac, Iona Grintescu, Liliana Mirea, Luz Serrano, Pilar Sierra, Sergi Sabate, Daniel Hernando, Purificacion Matute, Monsterrat Trashorras, Monsterrat sune, Laura Sarmiento, Adriana Hervias, Olga Gonzalez, Ana Hermina, Rosalia Navarro Perez, Mar Orts, Raquel Fernandez-Garcia, David Sanchez Perez, Isabel Sepulveda Gil, Pablo Monedero, Francisco Hidalgo, Cisse Mbongo, Anna Rodriguez Pont, Helena Mendez Reyes, Carolina Garcia Bartolo, Silvia Lopez Galera, Tabita Valentijn, Robert Jan Stolker, Mehmet Tugrul, Ebru Emre Demirel, Matthew Hough, Karen Griffiths, Sian Birch, Zoe Beardow, Stuart Elliot, Jonathan Thompson, Sarah Bowrey, Martin Northey, Helen Melson, Richard Telford, Maria Nadolski, Alison Potter, Debbie Fuller, Alastair Rose, Sandeep Varma, Karen Simeson, James Pettit, Neil Smith, Victoria Martinson, Lisa Sleight, Charde Naylor, Phil Watt, Parizade Raymode, Nigel Dunk, Linda Twohey, Laszlo Hollos, Simon Davies, Andy Gibson, Zoe Coleman, Tiina Tamm, Jozef Joscak, Lajos Zsisku, Mehrun Zuleika, Peter Carvalho, Thomas Collyer, James Ryan, Kerry Colling, Shan Dharmarajah, Asokan Krishnan, Jonathan Paddle, Anna Fouracres, Kim Arnell, Khalid Muhammad
BRITISH JOURNAL OF ANAESTHESIA
(2019)
Review
Anesthesiology
Jonathan Barnes, Jennifer Hunter, Steve Harris, Manu Shankar-Hari, Elisabeth Diouf, Ib Jammer, Cor Kalkman, Andrew A. Klein, Tomas Corcoran, Stefan Dieleman, Michael P. W. Grocott, Michael G. Mythen
BRITISH JOURNAL OF ANAESTHESIA
(2019)
Article
Medicine, General & Internal
Carol J. Peden, Tim Stephens, Graham Martin, Brennan C. Kahan, Ann Thomson, Kate Rivett, Duncan Wells, Gerry Richardson, Sally Kerry, Julian Bion, Rupert M. Pearse
Letter
Anesthesiology
Simon J. Howell
BRITISH JOURNAL OF ANAESTHESIA
(2019)
Editorial Material
Anesthesiology
Simon J. Howell
BRITISH JOURNAL OF ANAESTHESIA
(2019)
Article
Health Care Sciences & Services
Timothy J. Stephens, Carol J. Peden, Ryan Haines, Mike P. W. Grocott, Dave Murray, David Cromwell, Carolyn Johnston, Sarah Hare, Jose Lourtie, Sharon Drake, Graham P. Martin, Rupert M. Pearse
BMJ QUALITY & SAFETY
(2020)
Article
Medicine, General & Internal
John Taylor, Penny Wright, Hannah Rossington, Jackie Mara, Amy Glover, Nick West, Eva Morris, Phillip Quirke, Paul Finan, Nicholas West, Matthew Seymour, David Sebag-Montefoire, Daniel Swinson, Damian Tolan, Simon Howell, Peter Brown, Aidan Hindley, Emily Boldison
Article
Anesthesiology
Gabor Erdoes, Alain Vuylsteke, Jan-Uwe Schreiber, R. Peter Alston, Simon J. Howell, Patrick F. Wouters, Fabio Guarracino, Dragana Unic-Stojanovic, Alberto Hernandez Martinez, Marc Vives, Philippe Gaudard, Philippe Burtin, Dominique Bettex, Manuel Granell, Andrea Szekely, Joost van der Maaten, Theofani Antoniou, Maria Jose Jimenez, Laszlo Szegedi, Manfred Seeberger, Joachim M. Erb, Rajni Singh, Vera von Dossow, Purificacion Matute, Peter Rosseel, Nandor Marczin, Giovanni Landoni, Kirstin Wilkinson, Paul Diprose, Chirojit Mukherjee, Gianluca Paternoster, Mohamed R. El-Tahan
JOURNAL OF CARDIOTHORACIC AND VASCULAR ANESTHESIA
(2020)
Review
Anesthesiology
W. Scott Beattie, Manoj Lalu, Matthew Bocock, Simon Feng, Duminda N. Wijeysundera, Peter Nagele, Lee A. Fleisher, Andrea Kurz, Bruce Biccard, Kate Leslie, Simon Howell, Giovani Landoni, Hilary Grocott, Andre Lamy, Toby Richards, Paul Myles
Summary: Through a Delphi consensus process, this study identified nine standardized and valid cardiovascular outcomes for perioperative clinical trials, including myocardial infarction, cardiovascular death, and atrial fibrillation, which were rated by experts as valid, reliable, feasible, and clearly defined.
BRITISH JOURNAL OF ANAESTHESIA
(2021)
Article
Anesthesiology
Tom E. F. Abbott, Simon Howell, Rupert M. Pearse, Gareth L. Ackland
Summary: Blood pressure control during surgery is crucial in peri-operative care, and this study suggests that intra-arterial blood pressure monitoring may be associated with lower morbidity after surgery.
EUROPEAN JOURNAL OF ANAESTHESIOLOGY
(2021)
Article
Medicine, General & Internal
Thomas Dale MacLaine, Oliver Baker, Dermot Burke, Simon J. Howell
Summary: Frailty is prevalent in adult colorectal surgical patients of all ages, with poor agreement between three established frailty scoring instruments. Further research is needed to refine frailty scoring in surgical patients due to the significant prevalence of prefrailty and frailty across all age groups.
POSTGRADUATE MEDICAL JOURNAL
(2022)
Editorial Material
Anesthesiology
Simon J. Howell, Sherena Nair
BRITISH JOURNAL OF ANAESTHESIA
(2021)
Editorial Material
Anesthesiology
Simon J. Howell, Oliver I. Brown, W. Scott Beattie
BRITISH JOURNAL OF ANAESTHESIA
(2020)