期刊
EUROPEAN HEART JOURNAL
卷 35, 期 4, 页码 216-+出版社
OXFORD UNIV PRESS
DOI: 10.1093/eurheartj/eht461
关键词
Atrial fibrillation; Antithrombotic therapy; Triple therapy; Platelets; Acute coronary syndrome
资金
- Deutsche Forschungsgemeinschaft [OL371/1-1]
Many cardiac patients require combined antithrombotic therapy consisting of an anticoagulant and inhibition of platelet function. The most frequent indications are atrial fibrillation (AF) in combination with drug-eluting stent implantation and/or the presence of an acute coronary syndrome (ACS). Currently, the optimal combination of anticoagulants and anti-platelet therapy is unknown, but it is well established that the combination of regular doses and regimens as prescribed in AF or after ACS results in increased bleeding rates. In this review, we discuss the current literature and describe approaches to reduce the risk of bleeding hoping not to increase the rate of ischaemic events.
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