Article
Cardiac & Cardiovascular Systems
Rodrigue Garcia, Eloi Marijon, Nicole Karam, Kumar Narayanan, Frederic Anselme, Olivier Cesari, Laure Champ-Rigot, Vladimir Manenti, Raphael Martins, Etienne Puymirat, Jean Ferrieres, Francois Schiele, Tabassome Simon, Nicolas Danchin
Summary: The incidence and mortality of ventricular fibrillation (VF) among patients hospitalized for acute myocardial infarction (AMI) have significantly decreased over the past 20 years. However, VF remains associated with a 10-fold increased relative risk of in-hospital mortality, without affecting post-discharge mortality. These findings highlight the need for interventions during hospitalization to further reduce mortality in VF patients.
EUROPEAN HEART JOURNAL
(2022)
Article
Cardiac & Cardiovascular Systems
Meng Wang, Derick R. Peterson, Spencer Rosero, Scott McNitt, David Q. Rich, Christopher L. Seplaki, Bronislava Polonsky, Ilan Goldenberg, Wojciech Zareba
Summary: The study indicates that implantable cardioverter-defibrillators can reduce the risk of all-cause mortality, all-cause mortality before age 50 years, and sudden cardiac death in patients with long QT syndrome.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2021)
Article
Cardiac & Cardiovascular Systems
Anne-Lotte C. J. van der Lingen, Dominic A. M. J. Theuns, Mischa T. Rijnierse, Marthe A. J. Becker, Peter M. van de Ven, Albert C. van Rossum, Vokko P. van Halm, Michiel J. B. Kemme, Sing C. Yap, Cornelis P. Allaart
Summary: Male ICD patients were at higher risk of ADT and death compared with female ICD patients, irrespective of an ischaemic or non-ischaemic underlying cardiomyopathy. Our study highlights the importance to stratify outcomes of ICD trials by sex, as study results differ between men and women. However, none of the available clinical parameters showed a clear sex-specific relation to ventricular arrhythmias. As a consequence, sex-specific risk stratification models of SCD using commonly available clinical parameters could not be derived.
Article
Cardiac & Cardiovascular Systems
Federico Migliore, Raimondo Pittorru, Manuel De Lazzari, Alberto Cipriani, Barbara Bauce, Martina Perazzolo Marra, Enrico Giacomin, Pietro Bernardo Dall'Aglio, Stefano Accinelli, Sabino Iliceto, Domenico Corrado
Summary: This study evaluated the long-term outcome of patients with arrhyth-mogenic cardiomyopathy (ACM) who underwent third-generation subcutaneous implantable cardioverter defibrillator (S-ICD) implantation with the intermuscular (IM) two-incision technique. The findings showed that although the third-generation S-ICD with the IM two-incision technique appeared to have a low risk of complications and inappropriate shocks (IS) due to cardiac oversensing, the risk of IS due to myopotential mainly during effort should be considered.
INTERNATIONAL JOURNAL OF CARDIOLOGY
(2023)
Article
Medicine, General & Internal
Mariusz Klopotowski, Krzysztof Kukula, Jacek Jamiolkowski, Artur Oreziak, Maciej Dabrowski, Zbigniew Chmielak, Adam Witkowski
Summary: Hello, the aim of this study was to investigate how the calculated SCD risk in HCM patients with an ICD implanted in the past changed over time. The results showed that SCD risk in HCM patients is usually stable or gets lower, suggesting the need for re-evaluating the risk profile when considering ICD re-implantation.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Cardiac & Cardiovascular Systems
Jifu Jin, Guang Xia, Yu Luo, Ying Cai, Ying Huang, Zhiyun Yang, Qinghui Yang, Bing Yang
Summary: Coronary artery spasm (CAS) can cause severe and prolonged vessel constriction, leading to lethal ventricular arrhythmia. Tyrosine kinase inhibitors have been associated with CAS. Optimal medical treatment is the first-line therapy for CAS, while patients who have experienced aborted sudden cardiac death may benefit from implantable cardioverter-defibrillator (ICD) implantation.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2023)
Review
Biology
Fabrizio Guarracini, Alberto Preda, Eleonora Bonvicini, Alessio Coser, Marta Martin, Silvia Quintarelli, Lorenzo Gigli, Matteo Baroni, Sara Vargiu, Marisa Varrenti, Giovanni Battista Forleo, Patrizio Mazzone, Roberto Bonmassari, Massimiliano Marini, Andrea Droghetti
Summary: The difference between subcutaneous implantable cardioverter defibrillators (S-ICDs) and transvenous ICDs (TV-ICDs) lies in the extra-thoracic implantation of S-ICDs, without endovascular components. S-ICDs have been rapidly adopted due to their improved safety profile, especially among younger patients. Although S-ICDs show comparable efficacy, reliability, and safety outcomes to TV-ICDs, technical issues limit their employment, making them an alternative rather than a mainstream option.
Review
Cardiac & Cardiovascular Systems
Pietro Francia, Iacopo Olivotto, Pier D. Lambiase, Camillo Autore
Summary: Choosing the right ICD for patients with HCM is crucial, as overly complex devices may increase the risk of complications. Young patients stand to gain the most from ICD therapy but also face higher risks, necessitating careful consideration in device selection.
Article
Cardiac & Cardiovascular Systems
Pier D. Lambiase, Dominic A. Theuns, Francis Murgatroyd, Craig Barr, Lars Eckardt, Petr Neuzil, Marcoen Scholten, Margaret Hood, Jurgen Kuschyk, Amy J. Brisben, Nathan Carter, Timothy M. Stivland, Reinoud Knops, Lucas V. A. Boersma
Summary: This study reports the 5-year outcomes of EFFORTLESS registry patients with early generation subcutaneous implantable cardioverter-defibrillator (S-ICD) devices. The study found that the spontaneous shock efficacy remained consistently high over the 5-year period and very few patients required replacement with a transvenous device. Additionally, early arrhythmic episodes did not predict later complications.
EUROPEAN HEART JOURNAL
(2022)
Article
Cardiac & Cardiovascular Systems
Victor Waldmann, Christelle Marquie, Francis Bessiere, David Perrot, Frederic Anselme, Nicolas Badenco, Sergio Barra, Geraldine Bertaux, Hugues Blangy, Pierre Bordachar, Serge Boveda, Michel Chauvin, Nicolas Clementy, Gael Clerici, Nicolas Combes, Pascal Defaye, Jean-Claude Deharo, Philippe Durand, Guillaume Duthoit, Romain Eschalier, Laurent Fauchier, Rodrigue Garcia, Olivier Geoffroy, Edouard Gitenay, Jean-Baptiste Gourraud, Charles Guenancia, Laurence Iserin, Peggy Jacon, Laurence Jesel-Morel, Fawzi Kerkouri, Didier Klug, Linda Koutbi, Fabien Labombarda, Magalie Ladouceur, Gabriel Laurent, Christophe Leclercq, Baptiste Maille, Alice Maltret, Gregoire Massoulie, Pierre Mondoly, Sandro Ninni, Pierre Ollitrault, Jean-Luc Pasquie, Bertrand Pierre, Penelope Pujadas, Laure Champ-Rigot, Frederic Sacher, Nicolas Sadoul, Alexandre Schatz, Pierre Winum, Paul-Ursmar Milliez, Vincent Probst, Eloi Marijon
Summary: This study analyzed the outcomes of subcutaneous implantable cardioverter-defibrillators (S-ICDs) in patients with congenital heart disease (CHD). Among 4,924 patients who received an S-ICD implant, 101 had CHD. The study found that S-ICDs are effective and safe in patients with CHD.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Hitoshi Mori, Naokata Sumitomo, Kenta Tsutsui, Hideo Fukunaga, Hidemori Hayashi, Hiroshi Nakajima, Shota Muraji, Taisuke Nabeshima, Daisuke Kawano, Yoshifumi Ikeda, So Asano, Junichi Nitta, Shigeo Watanabe, Tatsunori Hokosaki, Seiichi Sato, Toshiyuki Chisaka, Takashi Higaki, Tadashi Nakajima, Shuntaro Tamura, Yoshiaki Kaneko, Kentaro Ikeda, Ayako Okada, Hideki Kobayashi, Hirohiko Motoki, Hitoshi Minamiguchi, Tomohiko Imamura, Satoshi Shizuta, Mitsuharu Kawamura, Yumi Munetsugu, Tsugutoshi Suzuki, Takashi Murakami, Hitoshi Horigome, Tsutomu Wada, Motoki Takamuro, Junichi Ozawa, Hiroshi Suzuki, Daisuke Izumi, Sou Otsuki, Masaomi Chinushi, Ken Kato, Masaru Miura, Jun Maeda, Masato Fukunaga, Hidekazu Kondo, Naohiko Takahashi, Takeshi Tobiume, Itsuro Morishima, Kenji Kuraishi, Kentaro Nakamura, Hiroshi Hayashi, Hirohiko Suzuki, Yukihiko Yoshida, Seiji Fukamizu, Rintaro Hojo, Norihito Nuruki, Masao Yoshinaga, Kentaro Hayashi, Hidehira Fukaya, Jun Kishihara, Toshiki Kobayashi, Ritsushi Kato
Summary: This study investigated the utility and safety of subcutaneous implantable cardioverter defibrillators (S-ICDs) in patients <= 18 years old. The results suggested that S-ICDs can effectively prevent sudden cardiac death in the pediatric population with a low incidence of lead complications or device infections. The number of suitable sensing vectors did not change during the patients' growth.
INTERNATIONAL JOURNAL OF CARDIOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Temirkhan Begisbayev, Lyazzat Kosherbayeva, Valikhan Akhmetov, Dmitry Khvan, Marzhan Brimzhanova
Summary: The number of ICD implantations in Kazakhstan is steadily increasing, but the rate of S-ICD implantation remains low due to factors such as insufficient personnel training, high device costs without reimbursement, and lack of pacing function. There is a need for deliberate strategies to remove policy barriers for implementing innovative cardiac implantable electronic devices implantation like S-ICD in the country.
Article
Cardiac & Cardiovascular Systems
Tom E. Verstraelen, Freyja H. M. van Lint, Laurens P. Bosman, Remco de Brouwer, Virginnio M. Proost, Bob G. S. Abeln, Karim Taha, Aeilko H. Zwinderman, Cathelijne Dickhoff, Toon Oomen, Bas A. Schoonderwoerd, Gerardus P. Kimman, Arjan C. Houweling, Juan R. Gimeno-Blanes, Folkert W. Asselbergs, Paul A. van der Zwaag, Rudolf A. de Boer, Maarten P. van den Berg, J. Peter van Tintelen, Arthur A. M. Wilde
Summary: This study aimed to develop a new mutation-specific prediction model for malignant VA in PLN p.Arg14del mutation carriers to improve risk stratification for primary prevention ICD implantation. The model outperformed the existing PLN risk model, indicating that using mutation-specific phenotypic features for risk prediction can enhance accuracy.
EUROPEAN HEART JOURNAL
(2021)
Article
Cardiac & Cardiovascular Systems
Tom E. Verstraelen, Freyja H. M. van Lint, Laurens P. Bosman, Remco de Brouwer, Virginnio M. Proost, Bob G. S. Abeln, Karim Taha, Aeilko H. Zwinderman, Cathelijne Dickhoff, Toon Oomen, Bas A. Schoonderwoerd, Gerardus P. Kimman, Arjan C. Houweling, Juan R. Gimeno-Blanes, Folkert W. Asselbergs, Paul A. van der Zwaag, Rudolf A. de Boer, Maarten P. van den Berg, J. Peter van Tintelen, Arthur A. M. Wilde
Summary: This study aimed to develop a new mutation-specific prediction model for malignant ventricular arrhythmia (VA) in phospholamban (PLN) p.Arg14del mutation carriers, and compared it to an existing PLN risk model. The new model demonstrated superior accuracy in predicting individual VA risk compared to the existing model.
EUROPEAN HEART JOURNAL
(2021)
Article
Cardiac & Cardiovascular Systems
Arjan Sammani, Rutger R. van de Leur, Michiel T. H. M. Henkens, Mathias Meine, Peter Loh, Rutger J. Hassink, Daniel L. Oberski, Stephane R. B. Heymans, Pieter A. Doevendans, Folkert W. Asselbergs, Anneline S. J. M. te Riele, Rene van Es
Summary: Inherently explainable DNNs can detect patients at risk of LTVA, mainly driven by P-wave abnormalities.
Article
Cardiac & Cardiovascular Systems
Marcio Jansen de Oliveira Figueiredo, Alejandro Cuesta, David Duncker, Serge Boveda, Federico Guerra, Manlio F. Marquez
Summary: Instant messaging (IM) platforms are widely used in the medical community in Latin America for sharing clinical data and discussing medical cases. The survey results show that most medical professionals in the region use IM apps to send and receive clinical data, with various types of data being shared. However, many respondents are not aware of the legal data protection regulations in their countries.
Article
Cardiac & Cardiovascular Systems
Hikmet Yorgun, Yusuf Ziya Sener, Nikita Tanese, Ahmet Keresteci, Burak Sezenoz, Cem Coteli, Ahmet Hakan Ates, Serge Boveda, Kudret Aytemir
Summary: The long-term safety and efficacy of left atrial appendage isolation (LAAi) in addition to pulmonary vein isolation (PVI) using cryoballoon (CB) in persistent atrial fibrillation (AF) were investigated in this study. The results showed that the LAAi + PVI strategy using CB had acceptable long-term outcomes in patients with persistent AF. However, systemic thrombo-embolic events were an important concern throughout the follow-up, especially in cases of non-adherence to anticoagulants.
Article
Pediatrics
Noel Peretti, Alexandre Vimont, Emmanuel Mas, Jean Ferrieres, Patrick Tounian, Julie Lemale, Franck Boccara, Mathilde Di Filippo, Sybil Charriere, Philippe Moulin, Pierre Poinsot, Yves Cottin, Pierre-Henri Ducluzeau, Caroline Dourmap, Bertrand Cariou, Michel Farnier, Francois Paillard, Alain Pradignac, Cecile Yelnik, Antonio Gallo, Eric Bruckert, Sophie Beliard
Summary: Childhood and parental factors, including genetic diagnosis and parental vascular disease, are associated with the initiation of statin therapy in children with HeFH. Genetic diagnosis may be useful for cardiovascular prevention in children.
JOURNAL OF PEDIATRICS
(2023)
Letter
Cardiac & Cardiovascular Systems
Stefano Bordignon, Serge Boveda, K. R. J. ulian Chun
Article
Cardiac & Cardiovascular Systems
Ana Carolina Schwab, Ante Anic, Michal M. Farkowski, Jose Guerra, Konstantinos E. Iliodromitis, Kristine Jubele, Rui Providencia, Julian K. R. Chun, Serge Boveda
Summary: This study conducted a survey to show how clinicians currently approach the knowledge gap in dealing with recurrences after a failed ablation for atrial fibrillation (AF). The majority of respondents perform routine monitoring for AF recurrences after ablation and prefer a long-term monitoring strategy. The combination of absence of symptoms and recorded AF is considered as the definition of success by most respondents.
Article
Cardiac & Cardiovascular Systems
Nikita Tanese, Alexandre Almorad, Luigi Pannone, Pascal Defaye, Sophie Jacob, Mouna Ben Kilani, Gianbattista Chierchia, Sandrine Venier, Christele Cardin, Peggy Jacon, Stephane Combes, Elodie Deschamps, Roberto Mene, Carlo de Asmundis, Serge Boveda
Summary: This study compared the procedural efficacy and safety, as well as the 12-month AF recurrence, between the PolarX and AFA-Pro cryoballoon systems. It was found that the PolarX cryoballoon reaches lower temperatures than the AFA-Pro, but it is associated with a higher rate of transient phrenic nerve palsy. No significant differences were observed in terms of 1-year freedom from AF recurrence between the two systems.
Article
Cardiac & Cardiovascular Systems
Bratislav Kircanski, Serge Boveda, Frits Prinzen, Antonio Sorgente, Ante Anic, Giulio Conte, Haran Burri
Summary: This article provides an overview of the current practice of conduction system pacing (CSP) in Europe, based on an online questionnaire sent to physicians, national societies, and through social media. The data collected includes previous experience, indications, tools, unmet needs, and future perspectives on CSP.
Review
Cardiac & Cardiovascular Systems
David S. Celermajer, David W. Baker, Rachael L. Cordina, Michael Gatzoulis, Craig S. Broberg
Summary: Due to advances in cardiac care, more patients with congenital heart disease are able to reach adulthood. It is important for general cardiologists to have a good understanding of adult congenital heart disease, including common errors and when to refer to a specialist center. This review provides case studies to help healthcare providers address common issues in adult congenital heart disease.
EUROPEAN HEART JOURNAL
(2023)
Article
Nutrition & Dietetics
Nicholas A. Koemel, Alistair M. Senior, David S. Celermajer, Amanda Grech, Tim P. Gill, Stephen J. Simpson, David Raubenheimer, Michael R. Skilton
Summary: This study evaluated the associations between macronutrient intake and all-cause, cardiovascular, and cancer mortality. It found that a high-calorie diet consisting of moderately high protein, moderate fat, and moderate carbohydrate levels was associated with the highest mortality risk. Lower mortality risk was observed in two separate regions consisting of higher protein, higher carbohydrate, and lower fat levels or lower protein, moderate carbohydrate, and higher fat levels. These findings highlight the complex nonlinear and interactive association between macronutrients and all-cause mortality.
Article
Cardiac & Cardiovascular Systems
Serge Boveda, Lucas Higuera, Colleen Longacre, Claudia Wolff, Kael Wherry, Kurt Stromberg, Mikhael F. El-Chami
Summary: This study compares the clinical outcomes between leadless pacemakers and transvenous ventricular pacemakers in subgroups of patients at higher risk of pacemaker complications. The results show that leadless pacemakers have lower rates of complications and reinterventions in several high-risk subgroups compared to transvenous ventricular pacemakers.
Article
Cardiac & Cardiovascular Systems
Victoria Gauthier, Martin Lafrance, Mael Barthoulot, Louis Rousselet, Michele Montaye, Jean Ferrieres, Samantha Huo Yung Kai, Katia Biasch, Marie Moitry, Philippe Amouyel, Jean Dallongeville, Aline Meirhaeghe
Summary: The study aimed to characterize the long-term risk of first recurrence of ACS among survivors of an incident ACS, based on the STEMI/NSTEMI/UA diagnosis. The risk of recurrence did not depend on the type of the incident ACS, but major complications and impaired LVEF increased the risk. The most frequent forms of recurrence were NSTEMI and UA.
INTERNATIONAL JOURNAL OF CARDIOLOGY
(2023)
Article
Health Care Sciences & Services
Jean Ferrieres, Eric Bruckert, Michel Farnier, Michel Krempf, Jean-Jacques Mourad, Baptiste Roux, Francois Schiele
Summary: This online survey studied French cardiologists' lipid-lowering approaches in patients with hypercholesterolemia and high cardiovascular risk. The results showed that most physicians underestimated the cardiovascular risk and selected higher-than-recommended LDL-C targets and less intensive treatment.
JOURNAL OF COMPARATIVE EFFECTIVENESS RESEARCH
(2023)
Article
Cardiac & Cardiovascular Systems
Anais Halin, Jean-Luc Hamelin, Pascal Defaye, Jean-Claude Deharo, Laurent Fauchier, Eloi Marijon, Olivier Piot, Serge Boveda
Summary: This study found that implantable cardioverter-defibrillator recipients lack sufficient information before the implantation, which is a concerning issue to be addressed. Patients' knowledge about implantable cardioverter-defibrillators needs improvement, especially in daily life, remote monitoring, and cardiac disease.
ARCHIVES OF CARDIOVASCULAR DISEASES
(2023)
Article
Cardiac & Cardiovascular Systems
Ante Anic, Darija Bakovic, Zrinka Jurisic, Michal Farkowski, Lucija Lisica, Toni Breskovic, Jens Erik Nielsen-Kudsk, Laura Perrotta, Carlo de Asmundis, Serge Boveda, Julian Chun
Summary: This study aims to investigate the diagnostic and therapeutic pathways for malignant LAA in European cardiac centers. The results show that most patients are treated on an outpatient basis, with a shift from VKA to DOAC. Left atrial appendage closure is only considered in patients with higher bleeding risk or complications.
Article
Cardiac & Cardiovascular Systems
Manoj Kumar Honaryar, Rodrigue Allodji, Gaelle Jimenez, Mathieu Lapeyre, Loic Panh, Jeremy Camilleri, David Broggio, Jean Ferrieres, Florent De Vathaire, Sophie Jacob
Summary: This study aimed to evaluate the development of atherosclerotic plaques over 2 years after breast cancer radiotherapy (RT) and their associations with cardiac exposure. The results showed that the risk of overall plaque development was significantly associated with doses to the coronary arteries.
JOURNAL OF CARDIOVASCULAR DEVELOPMENT AND DISEASE
(2023)