Stem and progenitor cell-based therapy in ischaemic heart disease: promise, uncertainties, and challenges

Rationale and design of Enhanced Angiogenic Cell Therapy in Acute Myocardial Infarction (ENACT-AMI): The first randomized placebo-controlled trial of enhanced progenitor cell therapy for acute myocardial infarction

(2010) Monica Taljaard et al.   AMERICAN HEART JOURNAL

Regulation of Bone Marrow-Derived Vascular Progenitor Cell Mobilization and Maintenance

(2010) Stefanie Dimmeler   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Enhancing the Outcome of Cell Therapy for Cardiac Repair

(2010) Emmanouil Chavakis et al.   CIRCULATION

Cardiomyogenic Potential of C-Kit + –Expressing Cells Derived From Neonatal and Adult Mouse Hearts

(2010) Marc-Michael Zaruba et al.   CIRCULATION

The acute and long-term effects of intracoronary Stem cell Transplantation in 191 patients with chronic heARt failure: the STAR-heart study

(2010) Bodo-Eckehard Strauer et al.   EUROPEAN JOURNAL OF HEART FAILURE

Granulocyte colony-stimulating factor attenuates left ventricular remodelling after acute anterior STEMI: results of the single-blind, randomized, placebo-controlled multicentre STem cEll Mobilization in Acute Myocardial Infarction (STEM-AMI) Trial

(2010) Felice Achilli et al.   EUROPEAN JOURNAL OF HEART FAILURE

Impaired Endothelial Repair Capacity of Early Endothelial Progenitor Cells in Prehypertension

(2010) Giovanna Giannotti et al.   HYPERTENSION

Pregenerative medicine: developmental paradigms in the biology of cardiovascular regeneration

(2010) B. Alexander Yi et al.   JOURNAL OF CLINICAL INVESTIGATION

Illuminating the Potential of Pluripotent Stem Cells

(2010) Anthony Rosenzweig   NEW ENGLAND JOURNAL OF MEDICINE

Patient-Specific Induced Pluripotent Stem-Cell Models for Long-QT Syndrome

(2010) Alessandra Moretti et al.   NEW ENGLAND JOURNAL OF MEDICINE

CXCR4 blockade augments bone marrow progenitor cell recruitment to the neovasculature and reduces mortality after myocardial infarction

(2010) K. Jujo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Synergy between CD26/DPP-IV Inhibition and G-CSF Improves Cardiac Function after Acute Myocardial Infarction

(2009) Marc-Michael Zaruba et al.   Cell Stem Cell

Stem Cell Therapy Is Proarrhythmic

(2009) Ester Macia et al.   CIRCULATION

Stem Cells Are Not Proarrhythmic: Letting the Genie out of the Bottle

(2009) Hung Q. Ly et al.   CIRCULATION

Engraftment, Differentiation, and Functional Benefits of Autologous Cardiosphere-Derived Cells in Porcine Ischemic Cardiomyopathy

(2009) Peter V. Johnston et al.   CIRCULATION

Cardiac Progenitor Cells and Biotinylated Insulin-Like Growth Factor-1 Nanofibers Improve Endogenous and Exogenous Myocardial Regeneration After Infarction

(2009) M. Elena Padin-Iruegas et al.   CIRCULATION

Repair of Acute Myocardial Infarction by Human Stemness Factors Induced Pluripotent Stem Cells

(2009) Timothy J. Nelson et al.   CIRCULATION

Functional Cardiomyocytes Derived From Human Induced Pluripotent Stem Cells

(2009) Jianhua Zhang et al.   CIRCULATION RESEARCH

Clinical Outcome 2 Years After Intracoronary Administration of Bone Marrow–Derived Progenitor Cells in Acute Myocardial Infarction

(2009) Birgit Assmus et al.   Circulation-Heart Failure

Bone marrow cell therapy after myocardial infarction. What should we select?

(2009) U. Landmesser   EUROPEAN HEART JOURNAL

Long-term myocardial functional improvement after autologous bone marrow mononuclear cells transplantation in patients with ST-segment elevation myocardial infarction: 4 years follow-up

(2009) F. Cao et al.   EUROPEAN HEART JOURNAL

Intracoronary bone marrow cell transfer after myocardial infarction: 5-year follow-up from the randomized-controlled BOOST trial

(2009) G. P. Meyer et al.   EUROPEAN HEART JOURNAL

Intracoronary infusion of bone marrow-derived selected CD34+CXCR4+ cells and non-selected mononuclear cells in patients with acute STEMI and reduced left ventricular ejection fraction: results of randomized, multicentre Myocardial Regeneration by Intracoronary Infusion of Selected Population of Stem Cells in Acute Myocardial Infarction (REGENT) Trial

(2009) Michał Tendera et al.   EUROPEAN HEART JOURNAL

Intracoronary infusion of bone marrow-derived mononuclear cells abrogates adverse left ventricular remodelling post-acute myocardial infarction: insights from the reinfusion of enriched progenitor cells and infarct remodelling in acute myocardial infarcti

(2009) Volker Schächinger et al.   EUROPEAN JOURNAL OF HEART FAILURE

Intramyocardial Bone Marrow Cell Injection for Chronic Myocardial Ischemia

(2009) Jan van Ramshorst et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Focused ultrasound-induced stimulation of microbubbles augments site-targeted engraftment of mesenchymal stem cells after acute myocardial infarction

(2009) Alexander Ghanem et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

The BALANCE Study

(2009) Muhammad Yousef et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

A Randomized, Double-Blind, Placebo-Controlled, Dose-Escalation Study of Intravenous Adult Human Mesenchymal Stem Cells (Prochymal) After Acute Myocardial Infarction

(2009) Joshua M. Hare et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Noninvasive Quantification and Optimization of Acute Cell Retention by In Vivo Positron Emission Tomography After Intramyocardial Cardiac-Derived Stem Cell Delivery

(2009) John Terrovitis et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Evidence for Cardiomyocyte Renewal in Humans

(2009) Olaf Bergmann et al.   SCIENCE

Murine “Cardiospheres” Are Not a Source of Stem Cells with Cardiomyogenic Potential

(2009) Ditte Caroline Andersen et al.   STEM CELLS

Donor-Derived Brain Tumor Following Neural Stem Cell Transplantation in an Ataxia Telangiectasia Patient

(2009) Ninette Amariglio et al.   PLOS MEDICINE

Assessing Identity, Phenotype, and Fate of Endothelial Progenitor Cells

(2008) Karen K. Hirschi et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Cell Delivery Mechanisms for Tissue Repair

(2008) David J. Mooney et al.   Cell Stem Cell

Generation of Functional Murine Cardiac Myocytes From Induced Pluripotent Stem Cells

(2008) Christina Mauritz et al.   CIRCULATION

Pilot Trial on Determinants of Progenitor Cell Recruitment to the Infarcted Human Myocardium

(2008) Volker Schächinger et al.   CIRCULATION

The Myoblast Autologous Grafting in Ischemic Cardiomyopathy (MAGIC) Trial

(2008) Philippe Menasché et al.   CIRCULATION

Genetic Enhancement of Stem Cell Engraftment, Survival, and Efficacy

(2008) Marc S. Penn et al.   CIRCULATION RESEARCH

Engineering Robust and Functional Vascular Networks In Vivo With Human Adult and Cord Blood–Derived Progenitor Cells

(2008) Juan M. Melero-Martin et al.   CIRCULATION RESEARCH

Autologous bone marrow stem cells to treat acute myocardial infarction: a systematic review

(2008) Enca Martin-Rendon et al.   EUROPEAN HEART JOURNAL

Stem Cell Mobilization by Granulocyte Colony-Stimulating Factor for Myocardial Recovery After Acute Myocardial Infarction

(2008) Dietlind Zohlnhöfer et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Pre-Treatment of Mesenchymal Stem Cells With a Combination of Growth Factors Enhances Gap Junction Formation, Cytoprotective Effect on Cardiomyocytes, and Therapeutic Efficacy for Myocardial Infarction

(2008) Joo-Yong Hahn et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Heart Failure-Related Hospitalization in the U.S., 1979 to 2004

(2008) Jing Fang et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Stem-cell therapy for cardiac disease

(2008) Vincent F. M. Segers et al.   NATURE

Immunosuppressive therapy mitigates immunological rejection of human embryonic stem cell xenografts

(2008) R.-J. Swijnenburg et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nuclear Reprogramming in Cells

(2008) J. B. Gurdon et al.   SCIENCE

Ex Vivo Pretreatment with Melatonin Improves Survival, Proangiogenic/Mitogenic Activity, and Efficiency of Mesenchymal Stem Cells Injected into Ischemic Kidney

(2008) Céline Mias et al.   STEM CELLS

Pulmonary Passage is a Major Obstacle for Intravenous Stem Cell Delivery: The Pulmonary First-Pass Effect

(2008) Uwe M. Fischer et al.   STEM CELLS AND DEVELOPMENT