4.5 Article

A bibliometric study of international scientific productivity in attention-deficit hyperactivity disorder covering the period 1980-2005

期刊

EUROPEAN CHILD & ADOLESCENT PSYCHIATRY
卷 17, 期 6, 页码 381-391

出版社

SPRINGER
DOI: 10.1007/s00787-008-0680-1

关键词

attention-deficit hyperactivity disorder; bibliometry; treatment; psychostimulants; methylphenidate

向作者/读者索取更多资源

Objective We have carried out a bibliometric analysis of scientific publications related to attention-deficit hyperactivity disorder (ADHD) and its pharmacological treatment over the period 1980-2005. Method We selected (in EMBASE and MEDLINE databases) documents that contained in their title the descriptors attention deficit hyperactivity disorder, attention deficit disorder, ADHD and ADD. As bibliometric indicators of production and dispersion we applied Price's Law and Bradford's Law, respectively. We also calculated the national participation index (PI) and correlated it with overall PI in biomedical and health sciences, with PI in the discipline of Psychiatry and with the social-health indicators (per capita Gross Domestic Product, number of physicians and total per capita expenditure on health). Results We obtained 5,269 original documents (2,325 corresponded to pharmacological therapy). Our results indicate fulfilment of Price's Law, since scientific production on ADHD undergoes exponential growth (correlation coefficient r = 0.9859, vs. r = 0.9011 after linear adjustment). The most widely studied drugs are methylphenidate (1,251 documents). Division into Bradford zones yields a nucleus occupied exclusively by the Journal of the American Academy of Child and Adolescent Psychiatry (500 articles). A total of 866 different journals were employed. Twelve of the first 20 used journals have an Impact Factor > 2. The principal producer country is the United States (PI = 44.2). Only four countries, of the 20 major producers in health sciences, surpass their own PI in the field of Psychiatry (Brazil, China, Spain and the United States). The correlation between PI and total number of physicians for each country situates Canada, Australia, the United States and Israel in the top positions. Conclusion Productivity on ADHD has undergone exponential growth in the period 1980-2005, without evidence a saturation point.

作者

我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。

评论

主要评分

4.5
评分不足

次要评分

新颖性
-
重要性
-
科学严谨性
-
评价这篇论文

推荐

Review Cell Biology

Coronavirus Disease 2019 (COVID-19) and Its Neuroinvasive Capacity: Is It Time for Melatonin?

Alejandro Romero, Eva Ramos, Francisco Lopez-Munoz, Emilio Gil-Martin, Germaine Escames, Russel J. Reiter

Summary: The COVID-19 pandemic caused by SARS-CoV-2 has become a significant global health concern. While the clinical symptoms are well-characterized, the mechanisms of how the virus invades and spreads in the central nervous system, causing brain damage, remain unclear. Recent findings of the virus in neural tissue highlight the need for neurotherapeutic strategies in COVID-19 patients with underlying diseases.

CELLULAR AND MOLECULAR NEUROBIOLOGY (2022)

Article International Relations

The role of doctors in torture: from middle age to Abu Ghraib

Esther Cuerda-Galindo, Francisco Lopez-Munoz

Summary: The role of medical personnel in torture has evolved significantly throughout history, from being officially required to be present in torture sessions to actively collaborating in the implementation of various torture methods. Efforts are needed to ensure that health professionals comply with international conventions and treaties against torture.

INTERNATIONAL POLITICS (2022)

Article Health Care Sciences & Services

Areas of Interest and Social Consideration of Antidepressants on English Tweets: A Natural Language Processing Classification Study

Laura de Anta, Miguel Angel Alvarez-Mon, Miguel A. Ortega, Cristina Salazar, Carolina Donat-Vargas, Javier Santoma-Vilaclara, Maria Martin-Martinez, Guillermo Lahera, Luis Gutierrez-Rojas, Roberto Rodriguez-Jimenez, Javier Quintero, Melchor Alvarez-Mon

Summary: Twitter users mainly discuss the effects of antidepressants on health-related areas, particularly sleep and appetite/weight. Patients and their relatives are the most frequent users posting tweets with medical content, while non-medical tweets often involve drug trivialization. Caregivers have a low presence in Twitter conversations about antidepressants.

JOURNAL OF PERSONALIZED MEDICINE (2022)

Article Nutrition & Dietetics

The Problem of Malnutrition Associated with Major Depressive Disorder from a Sex-Gender Perspective

Cielo Garcia-Montero, Miguel A. Ortega, Miguel Angel Alvarez-Mon, Oscar Fraile-Martinez, Adoracion Romero-Bazan, Guillermo Lahera, Jose Manuel Montes-Rodriguez, Rosa M. Molina-Ruiz, Fernando Mora, Roberto Rodriguez-Jimenez, Javier Quintero, Melchor Alvarez-Mon

Summary: This article explores the role of malnutrition in the onset and course of major depressive disorder (MDD) in women. Women are twice as likely to suffer from MDD compared to men, which is related to fluctuations in sexual hormones and dietary habits and nutritional requirements during specific life periods. Nutritional intervention programs with a gender perspective may potentially improve women's mental health and quality of life.

NUTRIENTS (2022)

Article Nutrition & Dietetics

Psychosocial Factors in Adolescence and Risk of Development of Eating Disorders

Fernando Mora, Miguel A. Alvarez-Mon, Sonia Fernandez-Rojo, Miguel A. Ortega, Miriam P. Felix-Alcantara, Isabel Morales-Gil, Alberto Rodriguez-Quiroga, Melchor Alvarez-Mon, Javier Quintero

Summary: This study analyzed the relationship between sociodemographic and behavioral factors, as well as self-esteem, in students of the first cycle of middle school and the likelihood of belonging to the risk group of eating disorders (ED). The results suggest that self-esteem is significantly related to belonging to an ED risk group, and variables related to dysfunctional feeding patterns are also associated with ED risk. These findings can help inform the development of effective preventive programs for EDs.

NUTRIENTS (2022)

Article Health Care Sciences & Services

Association between hospital internal medicine physician workforce and patient admissions during the COVID-19 pandemic in Japan

Seiji Hamada, Takuhiro Moromizato, Masashi Narita, Kiyosu Taniguchi, Kenji Shibuya, Yasuharu Tokuda

Summary: The number of hospital physicians in Japan is related to patient admissions, highlighting the importance of increasing the physician workforce to improve healthcare capacity.

BMC HEALTH SERVICES RESEARCH (2023)

Article Psychiatry

Assessment of beliefs and attitudes about electroconvulsive therapy posted on Twitter: An observational study

L. de Anta, M. A. Alvarez-Mon, C. Donat-Vargas, F. J. Lara-Abelanda, V. Pereira-Sanchez, C. Gonzalez Rodriguez, F. Mora, M. A. Ortega, J. Quintero, M. Alvarez-Mon

Summary: This study examines public views on electroconvulsive therapy (ECT) by analyzing Twitter posts. Healthcare providers were the main publishers of ECT-related content, but more than half of the tweets had joking or trivializing contents. Personal opinions on ECT were mostly negative.

EUROPEAN PSYCHIATRY (2023)

Article Biochemistry & Molecular Biology

Evidence of Increased Oxidative Stress in the Placental Tissue of Women Who Suffered an Episode of Psychosis during Pregnancy

Miguel A. Ortega, Oscar Fraile-Martinez, Cielo Garcia-Montero, Sonia Rodriguez-Martin, Rosa Funes M. Monux, Coral Bravo, Juan A. De Leon-Luis, Jose V. Saz, Miguel A. Saez, Luis G. Guijarro, Guillermo Lahera, Jorge Monserrat, Fernando Mora, Javier Quintero, Julia Bujan, Natalio Garcia-Honduvilla, Melchor Alvarez-Mon, Miguel Angel Alvarez-Mon

Summary: Psychosis is a complex clinical syndrome characterized by a loss of contact with reality and changes in behavior, senses, and motor functions. It can occur during pregnancy and have detrimental effects on maternal and fetal well-being. This study explored the role of oxidative stress in the placenta of women who experienced their first episode of psychosis during pregnancy. The findings suggest that oxidative stress markers may play a significant pathophysiological role in the placental tissue, contributing to the impact of psychosis on pregnancy.

ANTIOXIDANTS (2023)

Article Medicine, General & Internal

Decrease Retinal Thickness in Patients with Chronic Migraine Evaluated by Optical Coherence Tomography

Isidoro Raga-Martinez, Francisco J. Povedano-Montero, Jesus Hernandez-Gallego, Francisco Lopez-Munoz

Summary: The purpose of this study is to investigate the changes in retinal thickness in chronic migraine patients using optical coherence tomography (OCT). The study found that the thickness of the retinal nerve fibre layer and ganglion cell layer, as well as macular thickness, were significantly thinner in chronic migraine patients compared to healthy controls. These findings suggest that OCT can be used as a diagnostic tool for detecting retinal thinning in chronic migraines.

DIAGNOSTICS (2023)

Article Biochemistry & Molecular Biology

The Use of Second-Generation Antipsychotics in Patients with Severe Schizophrenia in the Real World: The Role of the Route of Administration and Dosage-A 5-Year Follow-Up

Juan J. Fernandez-Miranda, Silvia Diaz-Fernandez, Francisco Lopez-Munoz

Summary: In this 5-year observational study, the impact of route of administration and doses of second-generation antipsychotics (SGAs) on treatment adherence, hospital admissions, and suicidal behavior in patients with severe schizophrenia was assessed. Results showed that patients on oral antipsychotics (Aps) had higher treatment discontinuation rates and more hospitalizations compared to those on long-acting injectables (LAIs). Suicidal behavior was also less common in LAI-treated patients. Overall, LAI treatment was found to be more effective in managing severe schizophrenia.

BIOMEDICINES (2023)

Review Pharmacology & Pharmacy

Therapeutic Potential of Melatonin Counteracting Chemotherapy-Induced Toxicity in Breast Cancer Patients: A Systematic Review

Eva Ramos, Javier Egea, Francisco Lopez-Munoz, Emilio Gil-Martin, Alejandro Romero

Summary: The purpose of this systematic review is to summarize the knowledge on the therapeutic potential of melatonin in counteracting the negative effects of chemotherapy in breast cancer patients. The review analyzed preclinical and clinical evidence, identified gaps in the research, and suggested future studies. The selected randomized clinical trials indicated that combining melatonin with standard chemotherapy could improve the quality of life for breast cancer patients and increase partial response and 1-year survival rates.

PHARMACEUTICS (2023)

Review Biochemistry & Molecular Biology

Melatonin as Modulator for Sulfur and Nitrogen Mustard-Induced Inflammation, Oxidative Stress and DNA Damage: Molecular Therapeutics

Eva Ramos, Emilio Gil-Martin, Cristobal de los Rios, Javier Egea, Francisco Lopez-Munoz, Rene Pita, Antonio Juberias, Juan J. J. Torrado, Dolores R. R. Serrano, Russel J. J. Reiter, Alejandro Romero

Summary: In this review, melatonin is proposed as a therapeutic option to counteract the toxicological mechanisms and pathways activated after exposure to sulfur and nitrogen mustards. Additionally, the metabolites of melatonin are predicted to have a scavenger action and neutralize the damage induced by these blister agents. The anti-inflammatory action and NLRP3 inflammasome modulation of melatonin can also provide protection against sulfur and nitrogen mustard-induced injury.

ANTIOXIDANTS (2023)

Article Biochemistry & Molecular Biology

Neuroprotective and Antioxidant Properties of CholesteroNitrone ChN2 and QuinolylNitrone QN23 in an Experimental Model of Cerebral Ischemia: Involvement of Necrotic and Apoptotic Cell Death

Beatriz Chamorro, Sara Izquierdo-Bermejo, Maria Dolores Martin-de-Saavedra, Francisco Lopez-Munoz, Mourad Chioua, Jose Marco-Contelles, Maria Jesus Oset-Gasque

Summary: Ischemic stroke is a major cause of disability and death worldwide, and current therapeutic strategies are limited in their efficacy. Nitrones, known for their antioxidant and anti-inflammatory effects, show great promise as an alternative treatment. In this study, the neuroprotective effects of two nitrones were further investigated and compared with three reference compounds, showing significant neuroprotective effects.

ANTIOXIDANTS (2023)

Article Biochemistry & Molecular Biology

Redox Regulation of Microglial Inflammatory Response: Fine Control of NLRP3 Inflammasome through Nrf2 and NOX4

Alejandra Palomino-Antolin, Celine Decouty-Perez, Victor Farre-Alins, Paloma Narros-Fernandez, Ana Belen Lopez-Rodriguez, Maria Alvarez-Rubal, Ines Valencia, Francisco Lopez-Munoz, Eva Ramos, Antonio Cuadrado, Ana I. Casas, Alejandro Romero, Javier Egea

Summary: The role of inflammation and immunity in the pathomechanism of neurodegenerative diseases is significant. The NLRP3 inflammasome plays a crucial role in activating inflammatory responses. The interaction between NOX4 and Nrf2 is found to be critical in the activation of NLRP3 inflammasomes.

ANTIOXIDANTS (2023)

Article Psychiatry

Prevalence, comorbidities, and profiles of neurodevelopmental disorders according to the DSM-5-TR in children aged 6 years old in a European region

Lorena Frances, Antoni Ruiz, C. Virginia Soler, Joan Frances, Jessica Caules, Amaia Hervas, Carolina Carretero, Barbara Cardona, Elizabeth Quezada, Alberto Fernandez, Javier Quintero

Summary: The study found a high prevalence of neurodevelopmental disorders among 6-year-old children, with higher rates in boys than in girls. A significant proportion of cases had not been previously diagnosed, highlighting the importance of early detection programs and policies to support disadvantaged populations.

FRONTIERS IN PSYCHIATRY (2023)

暂无数据