Review
Cardiac & Cardiovascular Systems
Jayson R. Baman, Kaustubha D. Patil, Ankit N. Medhekar, Jane E. Wilcox
Summary: HFrecEF is recognized as a distinct clinical entity with increasing prevalence, and continued guideline-directed medical therapy is crucial to promote myocardial recovery. Despite the lower risk of sudden cardiac death in HFrecEF compared to HFrEF, the benefits of continued ICD therapy need to be weighed against potential risks and limitations.
JOURNAL OF CARDIAC FAILURE
(2021)
Article
Cardiac & Cardiovascular Systems
Mario Mekhael, Botao Shan, Charbel Noujaim, Nour Chouman, Alaa Assaf, Hadi Younes, Abdel Hadi El Hajjar, Lilas Dagher, Han Feng, Hua He, Cong Zhao, Omar Kreidieh, Chan Ho Lim, Chao Huang, Tarek Ayoub, Eugene Kholmovski, Mihail Chelu, Nassir Marrouche, Eoin Donnellan
Summary: The goal of this study was to assess the differences in post-ablation AF recurrence, burden, and LVEF changes in different CHF subcategories of the DECAAF-II population. The results showed no significant differences in AF recurrence and burden between CHF and non-CHF patients, as well as different CHF subcategories. Patients with HFrEF experienced the greatest improvement in LVEF after CA. Moreover, the improvement in ventricular function seemed to be independent of atrial fibrosis stages.
Review
Engineering, Biomedical
Philippe Maury, Maxime Beneyto, Pierre Mondoly, Hubert Delasnerie, Anne Rollin
Summary: This article reviews the natural course of patients with structural heart disease and sustained ventricular tachycardia who have not received ICD implantation and explores the potential role of catheter ablation alone in this population.
EXPERT REVIEW OF MEDICAL DEVICES
(2022)
Article
Cardiac & Cardiovascular Systems
Maura M. Zylla, Johannes Leiner, Ann-Kathrin Rahm, Tobias Hoffmann, Patrick Lugenbiel, Patrick Schweizer, Eberhard Scholz, Derliz Mereles, Dorothea Kronsteiner, Meinhard Kieser, Hugo A. Katus, Norbert Frey, Dierk Thomas
Summary: This study evaluates the outcome of cryoballoon ablation for atrial fibrillation in patients with heart failure with preserved ejection fraction (HFpEF). The results show that patients with HFpEF have a higher risk of atrial fibrillation recurrence and heart failure-related hospitalization after ablation. There is limited improvement in cardiac function and quality of life in these patients.
CIRCULATION-HEART FAILURE
(2022)
Article
Cardiac & Cardiovascular Systems
Zhengqin Zhai, Shuang Zhao, Xiaoyao Li, Keping Chen, Wei Xu, Wei Hua, Yangang Su, Min Tang, Zeyi Li, Shu Zhang
Summary: The interaction of electrical storm (ES) and impaired left ventricular ejection fraction (LVEF) significantly amplifies the deleterious effects of each other in patients with implantable cardioverter defibrillator (ICD).
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2022)
Review
Cardiac & Cardiovascular Systems
Magdy Abdelhamid, Giuseppe Rosano, Marco Metra, Stamatis Adamopoulos, Michael Boehm, Ovidiu Chioncel, Gerasimos Filippatos, Ewa A. Jankowska, Yury Lopatin, Lars Lund, Davor Milicic, Brenda Moura, Tuvia Ben Gal, Arsen Ristic, Amina Rakisheva, Gianluigi Savarese, Wilfried Mullens, Massimo Piepoli, Antoni Bayes-Genis, Thomas Thum, Stefan D. Anker, Petar Seferovic, Andrew J. S. Coats
Summary: Sudden death is a devastating complication of heart failure. Current guidelines recommend the use of implantable cardioverter-defibrillator (ICD) for prevention, but the evidence for its benefit in non-ischaemic HFrEF is limited. Recent data suggest that drugs such as BB, MRA, ARNI, and SGLT2i can reduce sudden cardiac death in HFrEF patients.
EUROPEAN JOURNAL OF HEART FAILURE
(2022)
Article
Cardiac & Cardiovascular Systems
Reza Mohebi, Yuxi Liu, G. Michael Felker, Margaret F. Prescott, Ileana L. Pina, Javed Butler, Jonathan H. Ward, Scott D. Solomon, James L. Januzzi
Summary: Sacubitril/valsartan therapy can improve left ventricular ejection fraction (LVEF) in heart failure (HF) patients, and a risk model can be developed to predict the persistence of LVEF improvement after treatment.
JACC-HEART FAILURE
(2023)
Article
Cardiac & Cardiovascular Systems
Lorne J. Gula, Asher Frydman, Habib R. Khan, George J. Klein, Peter Leong-Sit, Jaimie Manlucu, Jason D. Roberts, Anthony S. L. Tang, Raymond Yee, Allan C. Skanes
Summary: Patients with mildly impaired LV function and hemodynamically tolerated VT receive appropriate ICD therapies over the 3 years following implant. Recurrent VT/VF rates can be much more rapid after ICD placement, with 23% of patients going on to receive appropriate ICD shocks.
CANADIAN JOURNAL OF CARDIOLOGY
(2022)
Article
Cardiac & Cardiovascular Systems
Estelle Gandjbakhch, Mikael Laredo, Antonio Berruezo, Jean-Basptiste Gourraud, Jean-Marc Sellal, Raphael Martins, Frederic Sacher, Laurent Pison, Etienne Pruvot, Beatriz Jauregui, Antonio Frontera, Saurabh Kumar, Tom Wong, Paolo DellaBella, Philippe Maury
Summary: In patients with ARVC, well-tolerated MVT without a back-up ICD did not lead to fatal arrhythmic event after RCA despite VT recurrences in some. Our data suggest that RCA may be an alternative to ICD in selected ARVC patients.
Article
Cardiac & Cardiovascular Systems
Reo Hata, Takao Kato, Hidenori Yaku, Takeshi Morimoto, Yuichi Kawase, Erika Yamamoto, Yasutaka Inuzuka, Yodo Tamaki, Neiko Ozasa, Yusuke Yoshikawa, Takeshi Kitai, Yugo Yamashita, Moritake Iguchi, Kazuya Nagao, Takashi Morinaga, Yutaka Furukawa, Kazushige Kadota, Yukihito Sato, Takeshi Kimura
Summary: This study revealed that the use of ICD in Japanese patients with ADHF and reduced LVEF was associated with a significant reduction in the risk of arrhythmic events, but did not impact mortality rates.
JOURNAL OF CARDIOLOGY
(2021)
Article
Cardiac & Cardiovascular Systems
Marta Masini, Edoardo Elia, Pier Filippo Vianello, Giovanni Bertero, Paolo Rossi, Pietro Ameri, Francesco Chiarella, Claudio Brunelli, Italo Porto, Paolo Sartori, Marco Canepa
Summary: In this study, a total of 497 heart failure patients implanted with ICD for primary prevention were retrospectively evaluated, with the findings showing that neither appropriate nor inappropriate shocks independently increased mortality risk. Factors such as older age, atrial fibrillation, and lower LVEF were found to be associated with increased mortality risk. Further investigations are needed to understand the relationship between ICD shocks and survival in real-world primary prevention ICD recipients.
JOURNAL OF CARDIOVASCULAR MEDICINE
(2021)
Review
Cardiac & Cardiovascular Systems
Johanna B. Tonko, Christopher A. Rinaldi
Summary: Implantable cardioverter-defibrillators (ICDs) have revolutionized the treatment of cardiac diseases. However, there is a need for alternative ICD configurations due to expanding patient groups and increasing complications associated with traditional devices.
Article
Cardiac & Cardiovascular Systems
Vittoria Rizzello
Summary: The selection of patients eligible for implantable cardioverter defibrillator (ICD) in primary prevention is crucial for the management of cardiomyopathy patients. It requires a careful evaluation of the patients' arrhythmic risk, implantation-related risks, and device costs. Left ventricular ejection fraction alone is insufficient for identifying patients who would benefit the most from ICD. Genetic analysis and characterization of myocardial fibrosis with magnetic resonance imaging have shown significant improvement in this process.
EUROPEAN HEART JOURNAL SUPPLEMENTS
(2022)
Review
Medicine, General & Internal
Emmanuel Androulakis, Catrin Sohrabi, Alexandros Briasoulis, Constantinos Bakogiannis, Bunny Saberwal, Gerasimos Siasos, Dimitris Tousoulis, Syed Ahsan, Nikolaos Papageorgiou
Summary: Catheter ablation (CA) may be beneficial in improving functional status and reducing AF recurrence in patients with HFpEF, but it also comes with risks of post-procedural complications, hospitalization, and all-cause mortality.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Cardiac & Cardiovascular Systems
Hironori Ishiguchi, Yasuhiro Yoshiga, Akihiko Shimizu, Takeshi Ueyama, Masakazu Fukuda, Takayoshi Kato, Shohei Fujii, Masahiro Hisaoka, Tomoyuki Uchida, Takuya Omuro, Takayuki Okamura, Shigeki Kobayashi, Masafumi Yano
Summary: This study compared the incidence of major adverse clinical events (MACE) following catheter ablation for atrial fibrillation (AF) between patients with heart failure with preserved ejection fraction (HFpEF) and those with systolic heart failure (HF). The study found that the incidence of MACE was comparable between the two groups, suggesting that catheter ablation could be beneficial for HFpEF patients similar to those with systolic HF. However, other clinical events should also be considered cautiously in such patients.
Article
Cardiac & Cardiovascular Systems
Jean-Baptiste Guichard, Frederic Anselme, Pascal Defaye, Jacques Mansourati, Dominique Pavin, Jean-Luc Pasquie, Yannick Saludas, Jean-Claude Barthelemy, Frederic Roche, Silvy Laporte, Celine Chapelle, Arnauld Garcin, Cecile Romeyer, Karl Isaaz, Antoine Da Costa
Summary: The study investigated the effect of ramipril compared with placebo on atrial fibrillation occurrence in patients hospitalized for atrial flutter ablation, and found no significant difference between the two groups.
AMERICAN JOURNAL OF CARDIOLOGY
(2022)
Article
Medicine, General & Internal
Andrea Demarchi, Giulio Conte, Shih-Ann Chen, Li-Wei Lo, Wei-Tso Chen, Tom De Potter, Peter Geelen, Andrea Sarkozy, Francesco R. Spera, Tobias Reichlin, Laurent Roten, Pascal Defaye, Adrien Carabelli, Serge Boveda, Hamed Bourenane, Lisa Riesinger, Simon Kochhauser, Gala Caixal, Lluis Mont, Daniel Scherr, Martin Manninger, Francesco Pentimalli, Stefano Cornara, Catherine Klersy, Angelo Auricchio
Summary: This study evaluated the efficacy and long-term follow-up of catheter ablation in patients with previous pulmonary lobectomy/pneumonectomy history and atrial fibrillation. The results showed that catheter ablation by radiofrequency or cryoablation is feasible and safe for these patients, with similar efficacy observed in both males and females over a median follow up of 29.7 months.
JOURNAL OF CLINICAL MEDICINE
(2022)
Review
Cardiac & Cardiovascular Systems
Michal Miroslaw Farkowski, Michal Karlinski, Mariusz Pytkowski, Carlo de Asmundis, Michal Lewandowski, Giacomo Mugnai, Giulio Conte, Eloi Marijon, Ante Anic, Serge Boveda, Rui Providencia
Summary: This study systematically reviewed the effectiveness and safety of oral mexiletine in adult patients with structural heart disease and implantable cardioverter defibrillators for recurrent ventricular arrhythmia. The results showed that mexiletine reduced the number of ICD therapies, especially in patients where catheter ablation was not successful or contraindicated. However, in patients with ischemic cardiomyopathy, mexiletine seemed to be less effective than catheter ablation. The main side effects of mexiletine were related to gastrointestinal and neurological systems.
Article
Cardiac & Cardiovascular Systems
Marcio Jansen de Oliveira Figueiredo, Alejandro Cuesta, David Duncker, Serge Boveda, Federico Guerra, Manlio F. Marquez
Summary: Instant messaging (IM) platforms are widely used in the medical community in Latin America for sharing clinical data and discussing medical cases. The survey results show that most medical professionals in the region use IM apps to send and receive clinical data, with various types of data being shared. However, many respondents are not aware of the legal data protection regulations in their countries.
Article
Cardiac & Cardiovascular Systems
Hikmet Yorgun, Yusuf Ziya Sener, Nikita Tanese, Ahmet Keresteci, Burak Sezenoz, Cem Coteli, Ahmet Hakan Ates, Serge Boveda, Kudret Aytemir
Summary: The long-term safety and efficacy of left atrial appendage isolation (LAAi) in addition to pulmonary vein isolation (PVI) using cryoballoon (CB) in persistent atrial fibrillation (AF) were investigated in this study. The results showed that the LAAi + PVI strategy using CB had acceptable long-term outcomes in patients with persistent AF. However, systemic thrombo-embolic events were an important concern throughout the follow-up, especially in cases of non-adherence to anticoagulants.
Article
Cardiac & Cardiovascular Systems
Lukasz Januszkiewicz, Sergio Barra, Eloi Marijon, Rui Providencia, Carlo de Asmundis, Julian K. R. Chun, Michal M. Farkowski, Giulio Conte, Serge Boveda
Summary: This study aims to evaluate the information transmission to patients prior to ICD implantation and its impact on their quality of life. The findings show that although 71.5% of patients felt optimally informed at the time of implantation, many were not provided with information about ICD-related complications, driving restrictions, and end-of-life ICD deactivation. Women were less involved in the decision-making process and reported to be less often optimally informed before ICD implantation compared to men.
Letter
Cardiac & Cardiovascular Systems
Stefano Bordignon, Serge Boveda, K. R. J. ulian Chun
Article
Cardiac & Cardiovascular Systems
Ana Carolina Schwab, Ante Anic, Michal M. Farkowski, Jose Guerra, Konstantinos E. Iliodromitis, Kristine Jubele, Rui Providencia, Julian K. R. Chun, Serge Boveda
Summary: This study conducted a survey to show how clinicians currently approach the knowledge gap in dealing with recurrences after a failed ablation for atrial fibrillation (AF). The majority of respondents perform routine monitoring for AF recurrences after ablation and prefer a long-term monitoring strategy. The combination of absence of symptoms and recorded AF is considered as the definition of success by most respondents.
Article
Cardiac & Cardiovascular Systems
Nikita Tanese, Alexandre Almorad, Luigi Pannone, Pascal Defaye, Sophie Jacob, Mouna Ben Kilani, Gianbattista Chierchia, Sandrine Venier, Christele Cardin, Peggy Jacon, Stephane Combes, Elodie Deschamps, Roberto Mene, Carlo de Asmundis, Serge Boveda
Summary: This study compared the procedural efficacy and safety, as well as the 12-month AF recurrence, between the PolarX and AFA-Pro cryoballoon systems. It was found that the PolarX cryoballoon reaches lower temperatures than the AFA-Pro, but it is associated with a higher rate of transient phrenic nerve palsy. No significant differences were observed in terms of 1-year freedom from AF recurrence between the two systems.
Article
Cardiac & Cardiovascular Systems
Bratislav Kircanski, Serge Boveda, Frits Prinzen, Antonio Sorgente, Ante Anic, Giulio Conte, Haran Burri
Summary: This article provides an overview of the current practice of conduction system pacing (CSP) in Europe, based on an online questionnaire sent to physicians, national societies, and through social media. The data collected includes previous experience, indications, tools, unmet needs, and future perspectives on CSP.
Article
Cardiac & Cardiovascular Systems
Serge Boveda, Lucas Higuera, Colleen Longacre, Claudia Wolff, Kael Wherry, Kurt Stromberg, Mikhael F. El-Chami
Summary: This study compares the clinical outcomes between leadless pacemakers and transvenous ventricular pacemakers in subgroups of patients at higher risk of pacemaker complications. The results show that leadless pacemakers have lower rates of complications and reinterventions in several high-risk subgroups compared to transvenous ventricular pacemakers.
Review
Cardiac & Cardiovascular Systems
Lukasz Januszkiewicz, Sergio Barra, Rui Providencia, Julian K. R. Chun, Giulio Conte, Michal M. Farkowski, Jose M. Guerra, Eloi Marijon, Carlo de Asmundis, Serge Boveda
Summary: The aim of this study was to identify potential regional disparities in characteristics of ICD recipients, patient perceptions and perspectives after implantation and level of information provided to patients. The study found that patients in Western Europe reported higher satisfaction after ICD placement, while patients in Central/Eastern Europe felt more optimally informed at the time of device implantation. Therefore, novel strategies are needed to address regional differences in patients' quality of life and provision of information.
Article
Cardiac & Cardiovascular Systems
Anne-Celine Martin, Orianne Weizman, Jean-Marc Sellal, Vincent Algalarrondo, Walid Amara, Abdeslam Bouzeman, Estelle Gandjbakhch, Nicolas Lellouche, Jules Louembe, Aymeric Menet, Pierre Roumegou, Frederic Treguer, Anne Godier, Serge Boveda, Rodrigue Garcia, Eloi Marijon
Summary: The aim of this study is to investigate the impact of direct oral anticoagulant (DOAC) management on the incidence of pocket haematoma in patients undergoing pacemaker or implantable cardioverter-defibrillator implantation. The results of a large multicenter prospective observational study showed that the incidence of clinically relevant haematoma was low in patients with DOAC interruption, indicating that DOAC management can effectively reduce the risk of pocket haematoma.
Article
Cardiac & Cardiovascular Systems
Anais Halin, Jean-Luc Hamelin, Pascal Defaye, Jean-Claude Deharo, Laurent Fauchier, Eloi Marijon, Olivier Piot, Serge Boveda
Summary: This study found that implantable cardioverter-defibrillator recipients lack sufficient information before the implantation, which is a concerning issue to be addressed. Patients' knowledge about implantable cardioverter-defibrillators needs improvement, especially in daily life, remote monitoring, and cardiac disease.
ARCHIVES OF CARDIOVASCULAR DISEASES
(2023)
Article
Cardiac & Cardiovascular Systems
Ante Anic, Darija Bakovic, Zrinka Jurisic, Michal Farkowski, Lucija Lisica, Toni Breskovic, Jens Erik Nielsen-Kudsk, Laura Perrotta, Carlo de Asmundis, Serge Boveda, Julian Chun
Summary: This study aims to investigate the diagnostic and therapeutic pathways for malignant LAA in European cardiac centers. The results show that most patients are treated on an outpatient basis, with a shift from VKA to DOAC. Left atrial appendage closure is only considered in patients with higher bleeding risk or complications.