Gain-of-Function Mutations in UPC2 Are a Frequent Cause of ERG11 Upregulation in Azole-Resistant Clinical Isolates of Candida albicans

Regulation of Efflux Pump Expression and Drug Resistance by the Transcription Factors Mrr1, Upc2, and Cap1 in Candida albicans

(2011) Sabrina Schubert et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

An A643V Amino Acid Substitution in Upc2p Contributes to Azole Resistance in Well-Characterized Clinical Isolates ofCandida albicans

(2010) Samantha J. Hoot et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Azole Binding Properties of Candida albicans Sterol 14-  Demethylase (CaCYP51)

(2010) A. G. S. Warrilow et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

An A643T Mutation in the Transcription Factor Upc2p Causes Constitutive ERG11 Upregulation and Increased Fluconazole Resistance in Candida albicans

(2009) C. J. Heilmann et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Genomewide Location Analysis ofCandida albicansUpc2p, a Regulator of Sterol Metabolism and Azole Drug Resistance

(2008) Sadri Znaidi et al.   EUKARYOTIC CELL

A Gain-of-Function Mutation in the Transcription Factor Upc2p Causes Upregulation of Ergosterol Biosynthesis Genes and Increased Fluconazole Resistance in a ClinicalCandida albicansIsolate

(2008) Nico Dunkel et al.   EUKARYOTIC CELL

Cytoplasmic localization of sterol transcription factors Upc2p and Ecm22p in S. cerevisiae

(2008) Chelsea Marie et al.   FUNGAL GENETICS AND BIOLOGY

Mutations in the multi-drug resistance regulatorMRR1, followed by loss of heterozygosity, are the main cause ofMDR1overexpression in fluconazole-resistantCandida albicansstrains

(2008) Nico Dunkel et al.   MOLECULAR MICROBIOLOGY