Solubility-Promoting Function of Hsp90 Contributes to Client Maturation and Robust Cell Growth

Charged linker sequence modulates eukaryotic heat shock protein 90 (Hsp90) chaperone activity

(2012) S. Tsutsumi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Enforced N-domain Proximity Stimulates Hsp90 ATPase Activity and Is Compatible with Functionin Vivo

(2011) Lester Pullen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Charge-Rich Regions Modulate the Anti-Aggregation Activity of Hsp90

(2010) Natalie Wayne et al.   JOURNAL OF MOLECULAR BIOLOGY

Enhancing the Stability and Solubility of the Glucocorticoid Receptor Ligand-Binding Domain by High-Throughput Library Screening

(2010) Tobias Seitz et al.   JOURNAL OF MOLECULAR BIOLOGY

HSP90 at the hub of protein homeostasis: emerging mechanistic insights

(2010) Mikko Taipale et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Misfolded proteins impose a dosage-dependent fitness cost and trigger a cytosolic unfolded protein response in yeast

(2010) K. A. Geiler-Samerotte et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Charged Linker Region Is an Important Regulator of Hsp90 Function

(2009) Otmar Hainzl et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Modular Control of Cross-oligomerization

(2009) Natalie Wayne et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Hsp90 charged-linker truncation reverses the functional consequences of weakened hydrophobic contacts in the N domain

(2009) Shinji Tsutsumi et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The large conformational changes of Hsp90 are only weakly coupled to ATP hydrolysis

(2009) Moritz Mickler et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Dissection of the ATP-induced conformational cycle of the molecular chaperone Hsp90

(2009) Martin Hessling et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The Hsp110 protein chaperone Sse1 is required for yeast cell wall integrity and morphogenesis

(2008) Lance Shaner et al.   CURRENT GENETICS

Intra- and Intermonomer Interactions Are Required to Synergistically Facilitate ATP Hydrolysis in Hsp90

(2008) Christian N. Cunningham et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Species-Dependent Ensembles of Conserved Conformational States Define the Hsp90 Chaperone ATPase Cycle

(2008) Daniel R. Southworth et al.   MOLECULAR CELL

HSP90/70 chaperones are required for rapid nucleosome removal upon induction of the GAL genes of yeast

(2008) M. Floer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A yeast TDP-43 proteinopathy model: Exploring the molecular determinants of TDP-43 aggregation and cellular toxicity

(2008) B. S. Johnson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Multiple Conformations of E. coli Hsp90 in Solution: Insights into the Conformational Dynamics of Hsp90

(2008) Kristin A. Krukenberg et al.   STRUCTURE