Article
Veterinary Sciences
Hui Mi, Haobang Li, Weimin Jiang, Wu Song, Qiongxian Yan, Zhixiong He, Zhiliang Tan
Summary: This study investigated the effects of low-protein diets on blood calcium level, bone metabolism, and the correlation between the two in goats. The results showed that blood calcium concentration in mature goats can remain stable through nitrogen cycling even when protein intake is insufficient.
FRONTIERS IN VETERINARY SCIENCE
(2022)
Review
Biochemistry & Molecular Biology
Valeria Ciaffaglione, Enrico Rizzarelli
Summary: Dysregulated metal homeostasis, especially altered levels of zinc and copper, is associated with arthritic diseases. Carnosine emerges as a biomarker and exerts protective and osteogenic effects in arthritic joints. The zinc(II) complex, polaprezinc, also shows potential for bone fracture healing.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Review
Orthopedics
Yufeng Wang, Wei Zhang, Qingqiang Yao
Summary: Copper-based biomaterials have been increasingly used in tissue engineering for bone and cartilage repair, providing unique properties that enhance biological functions such as cell migration, adhesion, osteogenesis, chondrogenesis, angiogenesis, and antibacterial activities.
JOURNAL OF ORTHOPAEDIC TRANSLATION
(2021)
Article
Veterinary Sciences
Jannah Pye, Mathieu Spriet, Penny Dow, Scott Katzman, Brian G. Murphy
Summary: This study describes the clinical, imaging, gross, and histopathological abnormalities associated with osteochondral necrosis of the femoral condyles in foals, and identifies features suggestive of a common pathogenesis.
JAVMA-JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION
(2022)
Article
Endocrinology & Metabolism
Hetong Li, Yu Gou, Faming Tian, Ya Zhang, Qiangqiang Lian, Yunpeng Hu, Liu Zhang
Summary: The combined intervention of metformin and exercise showed significant preventative and therapeutic effects on osteoarthritis induced by estrogen deficiency and obesity, improving cartilage lesions and bone degeneration, as well as enhancing bone mass and microarchitecture.
Review
Biotechnology & Applied Microbiology
Sheeba Shakoor, Eleyna Kibble, Jehan J. El-Jawhari
Summary: This review discusses the roles of growth factors in bone and cartilage regeneration, as well as the methods of delivering these factors. Different tools such as scaffolds, encapsulation, layer-by-layer assembly, and hydrogels are used to deliver growth factors. Considering the advantages and limitations of these methods is crucial for the development of regenerative therapies.
BIOENGINEERING-BASEL
(2022)
Article
Agriculture, Dairy & Animal Science
Shaimaa Selim, Nazema S. Abdel-Megeid, Hanem K. Khalifa, Khloud G. Fakiha, Kamlah A. Majrashi, Eman Hussein
Summary: The present study aimed to evaluate the effects of various supplements on performance, nutrient digestibility, bone quality, and other parameters in broiler chickens fed a decreased non-phytate phosphorus diet. The results showed that the addition of phytase, multi-strain probiotic, Saccharomyces cerevisiae, and fumaric acid had beneficial effects on growth performance, health, nutrient digestibility, and bone quality of broilers.
Article
Agriculture, Dairy & Animal Science
Mengqi Liu, Chenyang Li, Haojia Tang, Maohua Gong, Zhengkai Yue, Man Zhao, Lei Liu, Fuchang Li
Summary: The study revealed that supplementing Lys in a low protein diet improved growth performance and nitrogen utilization in rabbits. It also regulated the expression of genes and proteins related to skeletal muscle development, showing potential for application in rabbit production.
JOURNAL OF ANIMAL PHYSIOLOGY AND ANIMAL NUTRITION
(2022)
Article
Cell & Tissue Engineering
H. J. Samvelyan, C. Huesa, L. Cui, C. Farquharson, K. A. Staines
Summary: In this study, we found that mice deficient in SOCS2 exhibited accelerated bone growth. However, this accelerated growth did not significantly impact vulnerability to osteoarthritis (OA).
BONE & JOINT RESEARCH
(2022)
Article
Agriculture, Dairy & Animal Science
Santi D. Upadhaya, Sang Seon Lee, Young Hwa Kim, Zhenlong Wu, In Ho Kim
Summary: This study evaluated the impact of supplementing glutamic acid to reduced protein diets on the growth performance of weanling pigs. The results showed that supplementing glutamic acid enhanced the body weight, average daily gain, and gain-to-feed ratio of the weanling pigs. The study also observed a linear increase in these growth parameters with increasing levels of glutamic acid. Additionally, the supplementation of glutamic acid had an effect on ammonia and methyl mercaptans emissions.
Article
Agriculture, Dairy & Animal Science
Laia Blavi, David Sola, Alessandra Monteiro, J. Francisco Perez, Hans H. Stein
Summary: The experiment showed that supplementing diets for growing pigs with Cu2O can improve growth performance and bone mineralization, with less copper accumulation in the liver compared to pigs fed diets containing CuSO4.
JOURNAL OF ANIMAL SCIENCE
(2021)
Article
Agriculture, Dairy & Animal Science
Mingfa Sun, Ning Ma, Hui Liu, Yu Liu, Yunlei Zhou, Jingpeng Zhao, Xiaojuan Wang, Haifang Li, Baishun Ma, Hongchao Jiao, Hai Lin
Summary: This study aimed to evaluate the optimal level of dietary Arg in the LP diet of hens. The results showed that the dietary Arg level in LP diet has significant quadratic effects on laying rate, egg mass, and feed efficiency. The LP diet deficient in Arg results in augmented oxidative damage and impaired development of intestinal mucosa.
JOURNAL OF ANIMAL SCIENCE AND BIOTECHNOLOGY
(2022)
Article
Nutrition & Dietetics
Xiaohua Huang, Yong Zhuo, Dandan Jiang, Yingguo Zhu, Zhengfeng Fang, Lianqiang Che, Yan Lin, Shengyu Xu, Lun Hua, Yuanfeng Zou, Chao Huang, Lixia Li, De Wu, Bin Feng
Summary: Maternal low-protein diet during puberty and adulthood may disrupt metabolic gene expression in the liver of offspring and exacerbate insulin resistance and hepatic steatosis in offspring fed a high-fat diet.
Article
Food Science & Technology
Efrat Monsonego Ornan, Ram Reifen
Summary: The high demand for sustainable protein sources requires re-evaluation of methods to assess their quality and bioavailability. A suggested physiological preclinical model based on postnatal growth can rapidly evaluate proteins from different sources.
Article
Materials Science, Biomaterials
Cong Du, Jian Hu, Xinyu Wu, Huimin Shi, Hai Chao Yu, Jin Qian, Jun Yin, Changyou Gao, Zi Liang Wu, Qiang Zheng
Summary: In this work, tough hydrogel constructs were fabricated using kappa-carrageenan/polyacrylamide double-network gels and toughened by soaking in zirconyl chloride solution. The obtained hydrogels showed good stability in water and possessed good mechanical properties. Optimized printing parameters allowed for the fabrication of 3D printed constructs with high aspect ratio and shape fidelity. Additionally, a biomimetic strategy was applied to create hydrogel composites by filling the tough hydrogel scaffold with a cell-laden fibrin hydrogel, demonstrating a favorable microenvironment for cells under cyclic compression.
JOURNAL OF MATERIALS CHEMISTRY B
(2022)
