Article
Medicine, General & Internal
Ji Yeong Kim, Yoo Na Kim, Yu Jung Lee, Sung Eun Sim, Yu Ri Ko, Jin Woo Shim, Ku Sang Lee, Mina Joo, Hue Jung Park
Summary: This study aimed to compare the analgesic efficacy of different drugs in the treatment of knee osteoarthritis patients, and found that polynucleotide sodium effectively reduced weight-bearing pain compared to standard hyaluronic acid viscosupplementation.
JOURNAL OF CLINICAL MEDICINE
(2021)
Review
Ophthalmology
Changce Sun, Xiaojun Zhang
Summary: This study systematically assessed the effect of recombinant human epidermal growth factor (rhEGF) associated with conventional drugs on dry eye symptoms in patients after cataract surgery. The results showed that this treatment significantly improved the success rate, decreased fluorescein staining score and dry eye symptom score, and prolonged tear break up time in the treatment group compared to the control group, indicating its effectiveness in treating dry eyes after cataract surgery.
JOURNAL OF OPHTHALMOLOGY
(2022)
Article
Biochemistry & Molecular Biology
Maria Addolorata Bonifacio, Amalia Cassano, Alessandra Vincenti, Angela Vinella, Fabio Dell'Olio, Gianfranco Favia, Maria Addolorata Mariggio
Summary: The timely and effective treatment of bone injuries is crucial for full recovery. A combination of hyaluronic acid and amino acids has been marketed for promoting soft tissue healing and accelerating recovery. This study investigates the effects of this combination on osteoblasts in vitro, aiming to understand its effectiveness in tissue repair.
Article
Emergency Medicine
Adam Holzmeister, Joseph Frazzetta, Frank Feng Ning Yuan, Arien Cherones, Hobie Summers, Joseph Cohen, William D. Lack
Summary: Multiple independent associations were identified in this study, involving variables related and unrelated to joint aspiration. The multivariable model performed well in discriminating between patients with and without septic arthritis.
AMERICAN JOURNAL OF EMERGENCY MEDICINE
(2021)
Article
Anesthesiology
Jee Youn Moon, Jeongsoo Kim, Jin Young Lee, Youngkwon Ko, Heu Jung Park, Young Hoon Jeon
Summary: This study compared the clinical effectiveness of sodium polynucleotide, classic hyaluronic acid, and crosslinked hyaluronic acid for the management of painful knee osteoarthritis. The results showed that polynucleotide significantly relieved pain more and relieved pain faster than classic and crosslinked hyaluronic acid, with improved health-related quality of life.
Article
Agriculture, Dairy & Animal Science
Stine Jacobsen, Camilla Drejer Mortensen, Elisabeth Alkaersig Hoj, Anne Mette Vinther, Lise Charlotte Berg, Ditte Marie Top Adler, Denis Verwilghen, Gaby van Galen
Summary: Early detection of joint infection in horses is crucial for preventing further damage and ensuring proper treatment. The biomarker NGAL has proven to be highly accurate in diagnosing joint infection in horses and monitoring treatment response. NGAL measurements may enable early detection and prompt therapy initiation, improving prognosis for horses with joint infection.
Article
Multidisciplinary Sciences
Woojin Kim, In Ho Woo, Youngsub Eom, Jong Suk Song
Summary: This study examined the short-term changes in tear osmolarity of dry eye patients after using artificial tears containing different osmolarities of sodium hyaluronate (SH). A total of 80 dry eye patients with tear osmolarity measurement of 300 mOsm/L or higher were included in the study. After being randomly divided into four groups, the participants received different concentrations of isotonic or hypotonic SH eye drops. The results showed that all types of SH eye drops significantly decreased tear osmolarity after 10 minutes, and the hypotonic SH eye drops had a greater immediate effect compared to the isotonic ones at 1 and 5 minutes.
SCIENTIFIC REPORTS
(2023)
Article
Cell & Tissue Engineering
R. G. E. Clement, A. C. Hall, S. J. Wong, S. E. M. Howie, A. H. R. W. Simpson
Summary: This study compared the effects of a haemolysin and the immune response on chondrocyte death in a murine joint model. The results showed that the haemolysin was the major cause of chondrocyte death, and the immune system also had a smaller deleterious role on cartilage.
BONE & JOINT RESEARCH
(2022)
Article
Orthopedics
Zahra Rezasoltani, Hadi Esmaily, Afsaneh Dadarkhah, Mansoure Rousta, Rezvaneh Mohebbi, Fatemeh Vashaei
Summary: This study compared the effects of low molecular-weight hyaluronic acid and physiotherapy on patients with supraspinatus tendinopathy. The results showed that hyaluronate was more effective in reducing shoulder pain, improving shoulder motion, and enhancing quality of life compared to physiotherapy. Both interventions were beneficial in managing tendinopathy, but hyaluronate had a better pain-alleviating effect.
JOURNAL OF THE AMERICAN ACADEMY OF ORTHOPAEDIC SURGEONS
(2021)
Review
Pharmacology & Pharmacy
Fahad A. Alshehri, Meshal S. Alharbi
Summary: This systematic review evaluated the effectiveness of hyaluronic acid (HA) as an adjunctive topical antibacterial agent in reducing the prevalence of P. gingivalis in subgingival biofilms during non-surgical mechanical therapy of periodontitis. Five clinical studies were included in the analysis, and only three studies provided data for meta-analysis at three and six months. The results did not support the use of HA to reduce the prevalence of P. gingivalis in subgingival biofilm.
Article
Multidisciplinary Sciences
Ji Eun Lee, Sangyoon Kim, Hyung Keun Lee, Tae-Young Chung, Jae Yong Kim, Chul Young Choi, So Hyang Chung, Dong Hyun Kim, Kyoung Woo Kim, Jin Kwon Chung, Kyu Yeon Hwang, Ho Sik Hwang, Jin Hyoung Kim, Joon Young Hyon
Summary: This study compared the efficacy and tolerability of hyaluronic acid and cyclosporine A eye drops in patients with moderate to severe dry eye syndrome. The results suggest that 0.15% hyaluronic acid may be equally effective and safer than 0.05% cyclosporine A in treating moderate to severe dry eye syndrome.
SCIENTIFIC REPORTS
(2022)
Article
Medicine, General & Internal
Qinglin Wu, Zuqing Wu, Zhifu Lu
Summary: This meta-analysis found that acupotomy combined with hyaluronic sodium acid is more effective than hyaluronic sodium acid alone in the treatment of knee osteoarthritis.
Article
Engineering, Biomedical
Xiangjian Liu, Yuying Hu, Yuxin Pan, Meirong Fang, Zhen Tong, Yilan Sun, Songwen Tan
Summary: The study found that medium molecular weight sodium hyaluronate (MSH) significantly increased the recovery rate of thawed red blood cells (RBCs) and maintained the functions and properties of RBCs. After direct washing of thawed RBCs, residual MSH could be removed, contributing to the increased recovery rate.
MATERIALS TODAY BIO
(2021)
Article
Veterinary Sciences
Jessica P. Johnson, Endrigo Pompermayer, Masa-aki Oikawa, Tatiana Vinardell, Mohammad Ali, Sarah Puchalski, Florent David
Summary: This study reports the clinical characteristics, surgical management, and medium-term outcomes of three Arabian neonatal foals with meniscal disruption associated with septic arthritis of the lateral femorotibial joint. The results indicate that meniscal disruption and infection should be considered in neonatal foals with persistent femorotibial septic arthritis, with the meniscus potentially being the primary nidus of infection.
EQUINE VETERINARY EDUCATION
(2023)
Article
Urology & Nephrology
Michael Baboudjian, Marc Fourmarier, Christophe Clement, Arnaud Cherasse, Jean-Pierre Graziana, Youssef Bentaleb, Yohann Rouscoff, Sylvain Ducrocq, Bastien Gondran-Tellier, Christian Saussine
Summary: This study assessed the efficacy and safety of intravesical instillation of high molecular weight sodium hyaluronate (HMW-HA) for radiation-induced cystitis. The results showed a significant reduction in symptoms and good tolerability of bladder instillation therapy with HMW-HA.
WORLD JOURNAL OF UROLOGY
(2022)
