Article
Agriculture, Dairy & Animal Science
Irene Nocera, Caterina Puccinelli, Micaela Sgorbini, Emma Bagnoli, Simonetta Citi
Summary: The present research evaluates the ultrasound features of metacarpal/tarsal-phalangeal joints in healthy racehorses, according to the age and breed. The study found that the cartilage appeared thinner in younger standardbreds compared to older ones, suggesting the use of specific references for ultrasound features. Specific ultrasound features and reference values have been reported for joint cartilage appearance and thickness in adult horses. Our results highlight the characteristics of ultrasound appearance of metacarpal/tarsal-phalangeal joints specifically in racehorses, with some variations according to age.
Article
Veterinary Sciences
Sigurdur F. Sigurdsson, Kristin Olstad, Charles J. Ley, Sigriour Bjornsdottir, David J. Griffiths, Cathrine T. Fjordbakk
Summary: The study used post-mortem arterial perfusion and micro-CT to examine tarsal bones in fetuses and foals up to 5 months old. It found that 61% of the animals had osteochondrosis lesions, which were related to vascular failure and requires further investigation.
EQUINE VETERINARY JOURNAL
(2022)
Article
Agriculture, Dairy & Animal Science
Chris W. Rogers, Erica K. Gee, Keren E. Dittmer
Summary: Horses reach skeletal maturity by 2 years old, with little variation in maturity age among breeds. They are capable of athletic activity relatively early in life, and the exercise should be matched with musculoskeletal development to optimize welfare and longevity in racing and sport. The growth and development of horses can be compared with human growth using measures of physeal closure and somatic growth.
Article
Veterinary Sciences
Lynn Pezzanite, Lyndah Chow, Dean Hendrickson, Daniel L. Gustafson, A. Russell Moore, Jason Stoneback, Gregg M. Griffenhagen, Gabriella Piquini, Jennifer Phillips, Paul Lunghofer, Steven Dow, Laurie R. Goodrich
Summary: This study investigated the effects of injecting different doses of amikacin on immune and cartilage responses in equine joints. High doses of amikacin may increase inflammatory cytokines and cartilage degradation biomarkers in synovial fluid, indicating potential harm and suggesting the consideration of lower doses for intra-articular antibiotic administration.
FRONTIERS IN VETERINARY SCIENCE
(2021)
Article
Agriculture, Dairy & Animal Science
Marcos Perez-Nogues, Javier Lopez-Sanroman, Michael Spirito, Gabriel Manso-Diaz
Summary: Subchondral cystic lesions (SCLs) are bone diseases that develop in young horses and can lead to lameness and poor performance. This study compared four treatments for SCLs in horses and found similar prognoses. Horses with larger SCLs had lower racing performance.
Article
Veterinary Sciences
Elizabeth A. Marchant, Stacy A. Semevolos
Summary: This study identified differential protein expression in the marginal transitional zone of foals affected by osteochondrosis, particularly involving components of extracellular matrix homeostasis and canonical Wnt signaling.
JOURNAL OF EQUINE VETERINARY SCIENCE
(2022)
Article
Veterinary Sciences
Bjorn H. Wormstrand, Cathrine T. Fjordbakk, David J. Griffiths, Sigrid Lykkjen, Kristin Olstad
Summary: The study described the development of blood supply to the growth cartilage of the medial femoral condyle in fetuses and foals, finding that the number of vessels increased before decreasing postnatally and the blood supply pathway changed with age. These results may contribute to our understanding of growth cartilage vascular failure and osteomyelitis.
EQUINE VETERINARY JOURNAL
(2021)
Article
Parasitology
Ghismon-de-Kasin Mayinda, Delphine Serreau, Amandine Gesbert, Fabrice Reigner, Jean-Francois Sutra, Anne Lespine, Guillaume Salle
Summary: Treatment of lactating mares with ivermectin may lead to suboptimal exposure to the drug in their foals, potentially contributing to selection for more resistant parasites. The study results indicated limited but sustained plasmatic exposure in foals associated with non-significant reduction in fecal egg count.
VETERINARY PARASITOLOGY
(2021)
Article
Veterinary Sciences
S. Hoey, D. Stokes, H. McAllister, A. Puggioni, C. Skelly
Summary: This systematic review examines the evidence for using ultrasonography in comparison to traditional radiography, arthroscopy or necropsy findings in the detection of osteochondrosis in horses. The review found a lack of strong evidence confirming the diagnostic accuracy and validity of ultrasonography in detecting osteochondral lesions in horses.
VETERINARY JOURNAL
(2022)
Article
Veterinary Sciences
K. L. Pimentel, A. L. Allen, J. L. Carmalt
Summary: A 15-month-old Quarter Horse filly presented with hard swellings over the left temporomandibular joint (TMJ) and right metatarsophalangeal joint (MTPJ), which were found to be severe osteoarthrosis with osteochondrosis-like lesions. The filly was euthanized due to poor prognosis, and post-mortem examination revealed early osteoarthritis associated with osteochondrosis-like lesions in the TMJ and MTPJ joints. Early OA was also diagnosed in the right hind proximal interphalangeal joint (PIPJ).
EQUINE VETERINARY EDUCATION
(2022)
Article
Critical Care Medicine
Simo K. Vilkki
Summary: This article introduces the development of a surgical technique for the replacement of the resected ulna head and describes the excellent long-term result achieved in the last case with 26-year follow-up. Although today many sophisticated prosthetic replacement techniques have become developed for this purpose, this kind of autogenous reconstruction might have a place in treating similar problems in young posttraumatic patients. It also demonstrates the potential benefit of microsurgery in a difficult wrist problem.
INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED
(2021)
Article
Veterinary Sciences
A. L. Labordere, D. H. Rodgerson, L. A. Kennedy
Summary: This case report describes the treatment and outcome of a 3.5-month-old lame foal with pneumonia associated with Rhodococcus equi. Despite prevention and adequate treatment, the unusual location of Rhodococcus equi osteomyelitis in the scapulohumeral joint led to euthanasia of the patient.
EQUINE VETERINARY EDUCATION
(2022)
Article
Veterinary Sciences
Elsa K. Ludwig, Kim Hallowell, Mandy Womble, Erin O'Neil
Summary: This is a case report of a 2-day-old horse with decreased nursing behavior and right hindlimb lameness. The foal had luxation of the right patella, inability to extend or bear weight on the hindlimbs, and assumed a crouched position. Stifle radiographs showed abnormal ossification of both patellae. Due to the severity of musculoskeletal defects, euthanasia was chosen. Post-mortem examination revealed congenital malformation of the patella bones and cardiac changes suggestive of right atrioventricular valve dysplasia. To our knowledge, bilateral congenital patellar aplasia has not been previously described in foals.
VETERINARY MEDICINE AND SCIENCE
(2023)
Review
Veterinary Sciences
Michelle Abraham, Jennifer Bauquier
Summary: The peripartum period is crucial for the health of mares and neonatal foals. Advances have been made in understanding the causes of perinatal fetal and foal loss in horses. Continued progress in reproductive and neonatal medicine will contribute to better survival rates for foals.
VETERINARY JOURNAL
(2021)
Article
Biochemistry & Molecular Biology
Fernando Canonici, Cristiano Cocumelli, Antonella Cersini, Daniele Marcoccia, Alessia Zepparoni, Annalisa Altigeri, Daniela Caciolo, Cristina Roncoroni, Valentina Monteleone, Elisa Innocenzi, Cristian Alimonti, Paola Ghisellini, Cristina Rando, Eugenia Pechkova, Roberto Eggenhoeffner, Maria Teresa Scicluna, Katia Barbaro
Summary: Cartilage injuries in animals and humans can lead to the progression of osteoarthritis and joint deterioration. A new experimental protocol for treating osteochondral lesions involves isolating chondrocytes from equine hyaline cartilage and using them to repair equine joint cartilage injuries. The chondrocytes, taken from autologous tracheal cartilage, are grown in a laboratory and implanted arthroscopically into the injured joint. Histological and immunohistochemical evaluation of the treated cartilage after 8 and 13 months shows progressive maturation, with tissue comparable to native articular cartilage detected after 24 months.
Article
Engineering, Environmental
Christine Cuyler, Janice Rowell, Jan Adamczewski, Morgan Anderson, John Blake, Tord Bretten, Vincent Brodeur, Mitch Campbell, Sylvia L. Checkley, H. Dean Cluff, Steeve D. Cote, Tracy Davison, Mathieu Dumond, Barrie Ford, Alexander Gruzdev, Anne Gunn, Patrick Jones, Susan Kutz, Lisa-Marie Leclerc, Conor Mallory, Fabien Mavrot, Jesper Bruun Mosbacher, Innokentiy Mikhailovich Okhlopkov, Patricia Reynolds, Niels Martin Schmidt, Taras Sipko, Mike Suitor, Matilde Tomaselli, Bjornar Ytrehus
Article
Veterinary Sciences
Turid Vikoren, Jorn Vage, Knut I. Madslien, Knut H. Roed, Christer M. Rolandsen, Linh Tran, Petter Hopp, Vebjorn Veiberg, Marianne Heum, Torfinn Moldal, Carlos G. das Neves, Kjell Handeland, Bjornar Ytrehus, Oyvor Kolbjornsen, Helene Wisloff, Randi Terland, Britt Saure, Kine M. Dessen, Solveig Gjerden Svendsen, Brit S. Nordvik, Sylvie L. Benestad
JOURNAL OF WILDLIFE DISEASES
(2019)
Article
Veterinary Sciences
Kristin Olstad, Bjorn Wormstrand, Jorgen Kongsro, Eli Grindflek
BMC VETERINARY RESEARCH
(2019)
Article
Veterinary Sciences
Bjorn H. Wormstrand, Cathrine T. Fjordbakk, David J. Griffiths, Sigrid Lykkjen, Kristin Olstad
Summary: The study described the development of blood supply to the growth cartilage of the medial femoral condyle in fetuses and foals, finding that the number of vessels increased before decreasing postnatally and the blood supply pathway changed with age. These results may contribute to our understanding of growth cartilage vascular failure and osteomyelitis.
EQUINE VETERINARY JOURNAL
(2021)
Article
Veterinary Sciences
Knut Madslien, Solveig Marie Stubsjoen, Hildegunn Viljugrein, Bjornar Ytrehus, Erling Johan Solberg, Lucy Kapronczai, Atle Mysterud, Jacques Godtroid, David M. Janz, Marc Cattet
JOURNAL OF WILDLIFE DISEASES
(2020)
Article
Multidisciplinary Sciences
Fredrik K. Murer, Basab Chattopadhyay, Aldritt Scaria Madathiparambil, Kim Robert Tekseth, Marco Di Michiel, Marianne Liebi, Magnus B. Lilledahl, Kristin Olstad, Dag W. Breiby
Summary: In this study, X-ray diffraction tensor tomography was used to non-destructively image the orientation of HA in a piglet's medial femoral condyle, revealing local variations and predominantly front-directed orientation. The ability to retrieve 3D orientation maps of bone-cartilage structures is expected to enhance understanding of the physiological properties of bones.
SCIENTIFIC REPORTS
(2021)
Article
Multidisciplinary Sciences
Atle Mysterud, Bjornar Ytrehus, Michael A. Tranulis, Geir Rune Rauset, Christer M. Rolandsen, Olav Strand
SCIENTIFIC REPORTS
(2020)
Article
Veterinary Sciences
Sigurdur F. Sigurdsson, Kristin Olstad, Charles J. Ley, Sigriour Bjornsdottir, David J. Griffiths, Cathrine T. Fjordbakk
Summary: The study used post-mortem arterial perfusion and micro-CT to examine tarsal bones in fetuses and foals up to 5 months old. It found that 61% of the animals had osteochondrosis lesions, which were related to vascular failure and requires further investigation.
EQUINE VETERINARY JOURNAL
(2022)
Article
Immunology
Jonathan D. F. Wadsworth, Susan Joiner, Jacqueline M. Linehan, Kezia Jack, Huda Al-Doujaily, Helena Costa, Thea Ingold, Maged Taema, Fuquan Zhang, Malin K. Sandberg, Sebastian Brandner, Linh Tran, Turid Vikoren, Jorn Vage, Knut Madslien, Bjornar Ytrehus, Sylvie L. Benestad, Emmanuel A. Asante, John Collinge
Summary: This study investigated the zoonotic potential of CWD-infected Norwegian reindeer and moose by inoculating their brain tissue into transgenic mice overexpressing human prion protein. The results showed no evidence of prion transmission, indicating a low zoonotic potential for these isolates.
JOURNAL OF INFECTIOUS DISEASES
(2022)
Article
Veterinary Sciences
Kristin Olstad, Torunn Aasmundstad, Jorgen Kongsro, Eli Grindflek
Summary: This study used CT to examine the spine of pigs and found that vertebral body osteochondrosis caused kyphosis. CT was suitable for identifying wedge vertebrae, and articular process and rib joint osteochondrosis may represent incidental findings.
BMC VETERINARY RESEARCH
(2022)
Article
Environmental Sciences
Signe Christensen-Dalsgaard, Bjornar Ytrenus, Magdalene Langset, Jorgen Ree Wiig, Kim Magnus Baerum
Summary: Beachcast events, where a large number of seabird carcasses drift ashore, occur irregularly. A study in northern Norway investigated the cause of death in dead gulls found after mass mortality events, and found that drowning was the primary cause. Monitoring fishing operations revealed that bycatch in coastal purse seine fishery may be a potential cause of seabird mortality.
MARINE ENVIRONMENTAL RESEARCH
(2022)
Article
Veterinary Sciences
Kristin Olstad, Lars Erik Gangsei, Jorgen Kongsro
Summary: This study describes a method for labeling articular osteochondrosis lesions in CT scans of pig joints and reports new observations made during the labeling process. The study found that both lesion number and volume should be considered during breeding selection, and there is an apparent inverse relationship between lesion number and volume.
BMC VETERINARY RESEARCH
(2022)
Article
Microbiology
Kjersti Selstad Utaaker, Bjornar Ytrehus, Marie L. L. Davey, Frode Fossoy, Rebecca K. K. Davidson, Andrea L. L. Miller, Per-Anders Robertsen, Olav Strand, Geir Rune Rauset
Summary: Salt licks may serve as potential attraction sites for the transmission of gastrointestinal parasites from domestic sheep to wild reindeer. This study found DNA evidence of parasites in salt lick soil, as well as similar DNA in sheep, reindeer, and salt licks, suggesting spillover. The decline in reindeer calf recruitment rate could potentially be explained by infection with these sheep parasites, highlighting the importance of studying such attraction points in disease dynamics.
Article
Microbiology
Alsu Kuznetsova, Debbie McKenzie, Bjornar Ytrehus, Kjersti Selstad Utaaker, Judd M. M. Aiken
Summary: Chronic wasting disease (CWD) is a transmissible spongiform encephalopathy that negatively affects cervids. This study investigates the migration pathways of the infectious prion protein (PrPCWD) in soil profiles. Soil minerals and diverse soils were compared, and it was found that PrPCWD migrates differently in different soil types. The prevalence of clay minerals in the soil affects the binding ability of prions, which could impact the environmental transmission of CWD.
Meeting Abstract
Chemistry, Multidisciplinary
F. K. Murer, S. Sanchez, K. Olstad, M. Di Michiel, B. Chattopadhyay, D. W. Breiby
ACTA CRYSTALLOGRAPHICA A-FOUNDATION AND ADVANCES
(2021)