期刊
EPILEPSY RESEARCH
卷 85, 期 2-3, 页码 252-260出版社
ELSEVIER
DOI: 10.1016/j.eplepsyres.2009.03.020
关键词
Consciousness; Dystonic posturing; Hippocampal sclerosis; Motor automatisms; SPECT; Temporal lobe epilepsy
A combination of temporo-limbic hyperperfusion and extratemporal hypoperfusion was observed during complex partial seizures (CPS) in temporal lobe epilepsy (TLE). To investigate the clinical correlate of perfusion changes in TLE, we analyzed focal seizures of increasing severity using voxel-based analysis of ictal SPECT. We selected 26 pre-operative pairs of ictal-interictal SPECTs from adult mesial TLE patients, seizure-free after surgery. Ictal SPECTs were classified in three groups: motionless seizures (group ML, n = 8), seizures with motor automatisms (MA) without dystonic posturing (DP) (group MA, n = 8), and seizures with DP with or without MA (DP, n = 10). Patients of group ML had simple partial seizures (SPS), while others had CPS. Groups of ictal-interictal SPECT were compared to a control group using statistical parametric mapping (SPM).
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