The mechanism of action of retigabine (ezogabine), a first-in-class K+ channel opener for the treatment of epilepsy

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Randomized, double-blind, placebo-controlled trial of ezogabine (retigabine) in partial epilepsy

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Efficacy and safety of adjunctive ezogabine (retigabine) in refractory partial epilepsy

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Neural KCNQ (Kv7) channels

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Definition of drug resistant epilepsy: Consensus proposal by the ad hoc Task Force of the ILAE Commission on Therapeutic Strategies

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Expression profile and characterisation of a truncated KCNQ5 splice variant

(2008) Shuk Yin M. Yeung et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Guide to Receptors and Channels (GRAC), 3rd edition

(2008) S P H Alexander et al.   BRITISH JOURNAL OF PHARMACOLOGY

Antiepileptogenic and antiictogenic effects of retigabine under conditions of rapid kindling: An ontogenic study

(2008) Andréy Mazarati et al.   EPILEPSIA

Nervous system KV7 disorders: breakdown of a subthreshold brake

(2008) Snezana Maljevic et al.   JOURNAL OF PHYSIOLOGY-LONDON

Refinement of the Binding Site and Mode of Action of the Anticonvulsant Retigabine on KCNQ K+ Channels

(2008) W. Lange et al.   MOLECULAR PHARMACOLOGY

Isobolographic characterization of interactions of retigabine with carbamazepine, lamotrigine, and valproate in the mouse maximal electroshock-induced seizure model

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The non-opioid analgesic flupirtine is a modulator of GABAA receptors involved in pain sensation

(2008) Felicia Popovici et al.   BMC Pharmacology & Toxicology