期刊
JOURNAL OF SEPARATION SCIENCE
卷 38, 期 13, 页码 2260-2266出版社
WILEY-V C H VERLAG GMBH
DOI: 10.1002/jssc.201500207
关键词
Dietary supplements; Eurycoma longifolia; Liquid chromatography with tandem mass spectrometry; Quassinoids; Tongkat Ali
资金
- Ministry of Food and Drug Safety [13182MFD725]
- Basic Science Research Program through National Research Foundation of Korea (NRF) - Ministry [NRF-2014R1A1A1A05002840]
Tongkat Ali (Eurycoma longifolia) is one of the most popular traditional herbs in Southeast Asia and generally consumed as forms of dietary supplements, tea, or drink additives for coffee or energy beverages. In this study, the liquid chromatography with tandem mass spectrometry method for the simultaneous quantitation of six major quassinoids of Tongkat Ali (eurycomanone, 13,21-dihydroeurycomanone, 13 alpha (21)-epoxyeurycomanone, 14,15 beta-dihydroxyklaineanone, eurycomalactone, and longilactone) was developed and validated. Using the developed method, the content of the six quassinoids was measured in Tongkat Ali containing dietary supplement tablets or capsules, and the resulting data were used to confirm the presence of Tongkat Ali in those products. Among the six quassinoids, eurycomanone was the most abundant quassinoid in all samples tested. The developed method would be useful for the quality assessment of Tongkat Ali containing dietary supplements.
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