Letter
Medicine, General & Internal
John O. Fleming, Kolar Murthy
Summary: The Perspective article by Howell failed to acknowledge the significant contributions of William H. Oldendorf, a neurologist and member of the Institute of Electrical and Electronics Engineers, to the development of computed tomographic scanning. Oldendorf, who was the first neurologist elected to the National Academy of Sciences, created the first known prototype apparatus for CT in 1961, leading to a more direct and humane way of imaging the brain.
NEW ENGLAND JOURNAL OF MEDICINE
(2021)
Article
Pediatrics
Fiona M. Baumer, Nancy A. McNamara, Anthony L. Fine, Elia Pestana-Knight, Renee A. Shellhaas, Zihuai He, Daniel H. Arndt, William D. Gaillard, Sarah A. Kelley, Margot Nagan, Adam P. Ostendorf, Nilika S. Singhal, Laura Speltz, Kevin E. Chapman
Summary: In the US, benzodiazepines and antiseizure medications are the most common initial therapies prescribed for CSWS, but the study suggests that benzodiazepines and steroids are more effective than antiseizure medications. Treatment choice does not depend on baseline clinical variables, nor correlate with outcomes.
JOURNAL OF PEDIATRICS
(2021)
Article
Medicine, General & Internal
Ridha Fameen, Rinsha K. Pravin, S. Pooja, V Rashmi, Biraj Bhattarai, B. P. Abhishek
Summary: It is crucial to understand the impact of COVID-19 on children's speech and language skills, as there is a lack of studies in this area. Accurate diagnosis is essential for Speech-Language Pathologists to provide systematic therapy for these children.
CLINICAL CASE REPORTS
(2022)
Article
Orthopedics
Alessandro Aprato, Luisangelo Sordo, Angelo Costantino, Luigi Sabatini, Luca Barberis, Diego Testa, Alessandro Masse
Summary: The study reported a 15.7% conversion rate to total knee replacement (TKR) at 20 years after arthroscopic meniscectomy (AM), with significant predictors for subsequent TKR including female sex, older age, lateral meniscectomy, malalignment, and advanced chondral lesion. Age 60 to 70 years at the time of AM and lateral meniscectomy were negative predictor factors for achieving equal or superior Knee Injury and Osteoarthritis Outcome Score (KOOS) scores adjusted for age and sex.
ARTHROSCOPY-THE JOURNAL OF ARTHROSCOPIC AND RELATED SURGERY
(2021)
Article
Gastroenterology & Hepatology
Maanek Sehgal, Uri Ladabaum, Alka Mithal, Harminder Singh, Manisha Desai, Gurkirpal Singh
Summary: This study found that undergoing colonoscopy at ages 45-49 or 50-54 years was associated with substantial decreases in subsequent colorectal cancer incidence.
Article
Linguistics
Antonio Benitez-Burraco, Koji Hoshi, Elliot Murphy
Summary: This article reviews epilepsy-related aphasias associated with GRIN2A mutations, focusing on acquired childhood epileptic aphasias like Landau-Kleffner syndrome (LKS). Children with LKS exhibit syntactically simplified utterances, severe word finding difficulties, and severe phonological paraphasias in their spontaneous speech. The authors characterize LKS as a neural dysrhythmia and explore the relationship between EEG abnormalities, particularly those occurring during non-rapid eye movement (NREM) sleep as electrical status epilepticus, and sleeping disorders partly caused by GRIN2A mutations. They also discuss the involvement of neural processes such as sharp-wave ripples, sleep spindles, slow oscillations, and cross-frequency couplings in language-related processes that are disturbed in LKS, contributing to the linguistic profile of epileptic aphasias.
JOURNAL OF NEUROLINGUISTICS
(2023)
Article
Oncology
Sicheng Cai, Huiying Shi, Mengke Fan, Qin Zhang, Rong Lin
Summary: For patients under 50 years old with fewer than 3 NAAs that are 1-5 mm in size, the recurrence rate of NAA is lower compared to patients over 50 years old with the same findings. However, when adenomas are 5 mm or larger, or exceed 3 in number, the recurrence risk is similar between the two age groups.
FRONTIERS IN ONCOLOGY
(2022)
Editorial Material
Physics, Applied
Steven Kivelson, Shivaji Sondhi
Summary: In 1973, Philip Anderson published a paper presenting the resonating valence bond state, which is now recognized as a topologically ordered phase of matter, unable to be classified conventionally based on its patterns of symmetry breaking. Steven Kivelson and Shivaji Sondhi reflect on the impact of this paper over the past 50 years.
NATURE REVIEWS PHYSICS
(2023)
Review
Biochemistry & Molecular Biology
Ian A. Wilson, Robyn L. Stanfield
Summary: This passage outlines the discovery and role of key structures in the immune system, as well as the structural basis of the immune response to microbial pathogens, with an emphasis on the specificity and affinity of antibodies and antigen receptors.
JOURNAL OF BIOLOGICAL CHEMISTRY
(2021)
Editorial Material
Multidisciplinary Sciences
Pippa Wells
Summary: The discovery of 'weak neutral currents' at CERN 50 years ago was a crucial milestone in establishing the standard model of particle physics, and research in this field continues to progress.
Article
Forestry
Mingxin Liu, Gregory J. Jordan, Christopher P. Burridge, Laurence J. Clarke, Susan C. Baker
Summary: In managed forests, the recovery of ground-active beetle biodiversity in regeneration forests is affected by forest influence, landscape context, and other surrounding landscape characteristics. Different forest ages and landscape context classes significantly impact beetle composition, with predictors explaining 34.1% of total variance in beetle community turnover. While geographical locations play a major role, subtle influences from landscape context, forest influence, and other landscape configuration variables also affect the beetle community.
FOREST ECOLOGY AND MANAGEMENT
(2021)
Article
Clinical Neurology
Regina Trollmann, Ingo Borggraefe, Wolfgang Muller-Felber, Ulrich Brandl
Summary: Developmental and epileptic encephalopathies typically present in infancy and early childhood, with the new ILAE classification providing a more precise definition including electro-clinical phenotype, etiological spectrum, and associated comorbidities. Certain electro-clinical entities can now be classified as specific encephalopathies based on their genotype. EEG remains an important tool in the diagnosis and management of epileptic encephalopathies, particularly for identifying complications and monitoring treatment efficacy.
KLINISCHE NEUROPHYSIOLOGIE
(2021)
Article
Plant Sciences
Richard B. Flavell
Summary: In the past 50 years, there have been significant advancements in the field of plant science, particularly in understanding the role of plant chromosomes in programming plant life. Technologies such as comparative genomics and transgenesis have played key roles in revealing important features of genes and managing evolutionary dramas related to chromosomes. Through studying chromatin-based transcriptional and epigenetic mechanisms, researchers have elucidated processes involved in gene expression, 3-D nuclear architecture, and plant improvement.
Editorial Material
Medicine, General & Internal
Amanda Howe
Summary: This article reviews journalist Polly Morland's new book A Fortunate Woman, which is a follow-up to John Berger's classic novel A Fortunate Man from 1967. It details the changes that have occurred over 50 years in the rewards and challenges of primary care practice in small-town rural general practice in northern England.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
(2023)
Article
Nutrition & Dietetics
Anna Kokkinopoulou, Ioannis Pagkalos, Nikolaos E. Rodopaios, Alexandra-Aikaterini Koulouri, Eleni Vasara, Sousana K. Papadopoulou, Petros Skepastianos, Maria Hassapidou, Anthony G. Kafatos
Summary: The study found that Christian Orthodox Church fasting has a positive effect on metabolic syndrome (MetS) in adults over 50 years old. Fasters had lower waist circumference, cholesterol levels, folic acid levels, and blood pressure compared to non-fasters. They also consumed less calories and fat.
Article
Clinical Neurology
Stephanie Vanclooster, Johan Bilsen, Lieve Peremans, Jutte Van der Werff Ten Bosch, Genevieve Laureys, Elsie Willems, Sophie Genin, Patrick Van Bogaert, Philippe Paquier, Anna Jansen
DEVELOPMENTAL NEUROREHABILITATION
(2019)
Article
Audiology & Speech-Language Pathology
Hyo Jung De Smet, Philippe Paquier, Jo Verhoeven, Peter Marien
BRAIN AND LANGUAGE
(2013)
Article
Neurosciences
Mathieu Bourguignon, Xavier De Tiege, Marc Op de Beeck, Noemie Ligot, Philippe Paquier, Patrick Van Bogaert, Serge Goldman, Riitta Hari, Veikko Jousmaki
HUMAN BRAIN MAPPING
(2013)
Article
Clinical Neurology
Robbert-Jan Van Hooff, Ann De Smedt, Sylvie De Raedt, Maarten Moens, Peter Marien, Philippe Paquier, Jacques De Keyser, Raf Brouns
Article
Rehabilitation
Stephanie Vanclooster, Katelijne Van Hoeck, Lieve Peremans, Johan Bilsen, Jutte Van Der Werff Ten Bosch, Genevieve Laureys, Philippe Paquier, Anna Jansen
Summary: This study aimed to describe the experiences of childhood brain tumor survivors (CBTS) and key figures in their environment after returning to school, using the International Classification of Functioning, Disability and Health framework. The results showed that school support and professional aftercare were essential to alleviate the child's difficulties, and factors such as teacher attitude, parental involvement, and collaboration practices further influenced the reintegration process.
DISABILITY AND REHABILITATION
(2021)
Review
Geriatrics & Gerontology
Silke Coemans, Esli Struys, Dorien Vandenborre, Ineke Wilssens, Sebastiaan Engelborghs, Philippe Paquier, Kyrana Tsapkini, Stefanie Keulen
Summary: Various tDCS approaches have been used to explore the potential of tDCS in improving language outcomes or slowing down the decline of language competences in PPA cases. While the stimulation protocols and study designs in PPA are similar to post-stroke aphasic populations, differences in pathophysiology require further investigation to establish the optimal stimulation paradigm. Despite heterogeneity in patient populations, stimulation protocols, and study design, tDCS is considered an effective tool for improving language outcomes.
FRONTIERS IN AGING NEUROSCIENCE
(2021)
Review
Behavioral Sciences
Silke Coemans, Stefanie Keulen, Perseverence Savieri, Kyrana Tsapkini, Sebastiaan Engelborghs, Nini Chrispeels, Dorien Vandenborre, Philippe Paquier, Ineke Wilssens, Mathieu Declerck, Esli Struys
Summary: This study conducted a multi-level meta-analysis to investigate deficits in executive functions (EFs) in Primary Progressive Aphasia (PPA) patients. The results showed that PPA patients had poorer EFs compared to age-matched cognitively healthy controls. There were no significant differences between the effect sizes of different EFs components, indicating similar impairments across all components. PPA variant and disease duration were found to be significant moderators of performance.
Review
Linguistics
Anastasia Lada, Philippe Paquier, Christina Manouilidou, Stefanie Keulen
Summary: Idioms have unique semantic dimensions and studying their comprehension in clinical populations, particularly individuals with aphasia, can shed light on the role of the brain in processing idiomatic language. However, there is inconsistency in the literature regarding the existence and effects of certain factors on idiomatic comprehension. This study aimed to explore the impact of idiom stimuli and tasks on language performance in aphasia.
JOURNAL OF NEUROLINGUISTICS
(2023)
Article
Neurosciences
Silke Coemans, Esli Struys, Kyrana Tsapkini, Philippe Paquier, Dorien Vandenborre, Stefanie Keulen
Summary: Transcranial Direct Current Stimulation (tDCS) is a potential tool for enhancing speech and language therapy in individuals with aphasia. This study investigates the effects of applying anodal cerebellar tDCS (ctDCS) combined with language therapy in a bilingual patient with chronic post-stroke aphasia. The results showed that both sham and anodal treatment improved trained picture naming in the treated language (L2), while anodal ctDCS also improved picture naming of untrained items in both L2 and the patient's first language, L1. Picture description abilities improved in both languages after anodal ctDCS, but not after sham.
FRONTIERS IN HUMAN NEUROSCIENCE
(2023)
Article
Neurosciences
Cheyenne Svaldi, Philippe Paquier, Stefanie Keulen, Henrieke van Elp, Coriene Catsman-Berrevoets, Annet Kingma, Roel Jonkers, Saskia Kohnen, Vania de Aguiar
Summary: This study aims to identify language processing deficits for four levels of language processing in cerebellar tumour survivors. The results showed inter-individual heterogeneity in spontaneous language outcomes, with impairments observed across all levels of language processing. Moreover, patients with postoperative cerebellar mutism syndrome (pCMS) had predominantly morphosyntactic and semantic impairments.
Article
Psychiatry
S. Keulen, P. Marien, K. van Dun, T. D'aes, L. de Page, L. de Vroege, P. Van Schuerbeek, H. Raeymaekers, J. De Mey, R. Bastiaanse, C. Van der Feltz-Cornelis, P. Paquier, F. Van Overwalle, J. Verhoeven
Summary: This case analysis describes a 28-year-old native Dutch-speaking lady who developed Foreign Accent Syndrome (FAS) and jargon speech after experiencing trauma. The results of neuropsychological tests, fMRI experiment and psychodiagnostic exams indicate a functional etiology for the symptoms, consistent with a DSM-5 conversion disorder.
EUROPEAN JOURNAL OF PSYCHIATRY
(2021)
Article
Psychology, Clinical
Stephanie Vanclooster, Johan Bilsen, Lieve Peremans, Jutte Van der Werff Ten Bosch, Genevieve Laureys, Elsie Willems, Sophie Genin, Patrick Van Bogaert, Philippe Paquier, Anna Jansen
JOURNAL OF HEALTH PSYCHOLOGY
(2019)
Meeting Abstract
Oncology
Sophie Genin, Stephanie Vanclooster, Eric Sariban, Patrick Van Bogaert, Philippe Paquier
Meeting Abstract
Oncology
S. Vanclooster, S. Genin, S. Hardonk, L. Peremans, J. Van der Werff Ten Bosch, J. Bilsen, P. Paquier, A. Jansen
PEDIATRIC BLOOD & CANCER
(2015)
Article
Clinical Neurology
Claudine Sculier, Anne-Sophie Tilmant, Xavier De Tiege, Sanda Giurgea, Philippe Paquier, Gabrielle Rudolf, Gaetan Lesca, Patrick Van Bogaert
EPILEPTIC DISORDERS
(2017)
