Review
Microbiology
Anna Furuta, Alyssa Brokaw, Gygeria Manuel, Matthew Dacanay, Lauren Marcell, Ravin Seepersaud, Lakshmi Rajagopal, Kristina Adams Waldorf
Summary: Group B streptococci (GBS) are bacteria that can cause serious infections in newborns, leading to significant neurodevelopmental injury and disability.
FRONTIERS IN MICROBIOLOGY
(2022)
Article
Immunology
Francesc Escrihuela-Vidal, Luis Eduardo Lopez-Cortes, Laura Escola-Verge, Aristides De Alarcon Gonzalez, Guillermo Cuervo, Antonio Sanchez-Porto, Nuria Fernandez-Hidalgo, Rafael Luque, Miguel Montejo, Jose M. Miro, Miguel Angel Goenaga, Patricia Munoz, Maricela Valerio, Marco Ripa, Dolores Sousa-Regueiro, Merce Gurgui, Maria Carmen Farinas-Alvarez, Lourdes Mateu, Elisa Garcia Vazquez, Juan Galvez-Acebal, Jordi Carratala
Summary: The study found that Streptococcus anginosus group (SAG) endocarditis has a similar prognosis to endocarditis caused by viridans group streptococci (VGS) or Streptococcus gallolyticus group (SGG), with no significant differences in disease severity and outcomes.
OPEN FORUM INFECTIOUS DISEASES
(2021)
Review
Microbiology
Sarah Shabayek, Patricia Ferrieri, Barbara Spellerberg
Summary: Streptococcus agalactiae or group B streptococcus (GBS) is a significant pathogen globally and represents a high disease burden in Africa. Investigations in different African countries show that while some serotypes and MLST data are similar to other continents, there are also specific differences, with serotype V being predominant in maternal strains in many African countries.
Article
Infectious Diseases
Lei Yue, Haiying Liu
Summary: Late-onset Group B Streptococcus (GBS) meningitis occurred in two Chinese families, involving a set of dizygotic twins and a pair of compatriot siblings. GBS strains of serotype III CC17 were identified with high homology within each family, and the siblings' isolates matched their mother's carriage. The siblings developed symptoms days after close contact with their index cases, but received prompt diagnosis and treatment, resulting in better outcomes compared to the index patients who had brain damage and severe sequelae.
INFECTION AND DRUG RESISTANCE
(2023)
Article
Immunology
Li Zhang, Wen-Juan Kang, Lei Zhu, Li-Jun Xu, Chao Guo, Xin-Hua Zhang, Qing-Hua Liu, Lan Ma
Summary: Group B streptococcus (GBS) is a leading cause of serious infections in infants. The ST10 strain, particularly type Ib/ST10, is responsible for a significant proportion of infant invasive GBS infections in China, leading to serious clinical complications. Continued monitoring and research on this microbiological strain is crucial for understanding and addressing the ongoing emergence of multi-drug resistant GBS isolates.
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY
(2021)
Article
Infectious Diseases
Viivi Nevanlinna, Reetta Huttunen, Janne Aittoniemi, Tiina Luukkaala, Sari Rantala
Summary: This study investigated the incidence, seasonal pattern, clinical manifestations, and recurrence of Streptococcus dysgalactiae subspecies equisimilis (SDSE) bacteremia. A total of 217 episodes (involving 211 patients) were analyzed, with an average annual incidence rate of 16.9/100,000 inhabitants. The majority of episodes (33%) occurred during the summer, and bacteremic cellulitis was more common in the summer compared to other seasons. Cellulitis was the most common clinical manifestation of SDSE bacteremia.
EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES
(2023)
Article
Infectious Diseases
Fen Pan, Na Zhao, Wantong Zhao, Chun Wang, Yan Sun, Haomin Zhang, Juanxiu Qin, Qian Liu, Hong Zhang
Summary: This study demonstrated that the two MALDI-TOF MS systems could differentiate most VGS isolates, but with different identification performances. The Bruker Biotyper system tends to produce more misidentifications compared to the VITEK MS system.
INFECTION AND DRUG RESISTANCE
(2023)
Article
Immunology
R. Villarreal, H. S. Manzer, A. M. Keestra-Gounder, K. S. Doran
Summary: The study on the pathogenesis of GBS meningitis reveals the critical roles of vimentin and NOD2 in mediating inflammatory responses induced by GBS. Vimentin is essential for regulating the inflammation process, while NOD2 promotes chemokine induction in response to GBS infection, highlighting their importance in host immune responses against GBS invasion.
INFECTION AND IMMUNITY
(2021)
Article
Microbiology
Angelica Pellegrini, Germana Lentini, Agata Fama, Andrea Bonacorsi, Viola Camilla Scoffone, Silvia Buroni, Gabriele Trespidi, Umberto Postiglione, Davide Sassera, Federico Manai, Giampiero Pietrocola, Arnaud Firon, Carmelo Biondo, Giuseppe Teti, Concetta Beninati, Giulia Barbieri
Summary: Group B Streptococcus (GBS) is able to switch from a harmless commensal to a pathogen responsible for neonatal meningitis. This study investigates the role of CodY, a global transcriptional regulator, in GBS virulence. Deletion of codY reduces the ability of the mutant strain to cause infections in animal models. CodY controls gene expression related to amino acid transport and metabolism, as well as surface proteins and virulence factors. Its activity is dependent on the availability of branched-chain amino acids.
FRONTIERS IN MICROBIOLOGY
(2022)
Article
Infectious Diseases
Viivi Nevanlinna, Reetta Huttunen, Janne Aittoniemi, Tiina Luukkaala, Sari Rantala
Summary: This study aimed to investigate the risk factors associated with S. dysgalactiae subsp. equisimilis bacteremia. Using the Finhealth study data in Finland, it was found that obesity, diabetes, and coronary artery disease were associated with an increased risk of S. dysgalactiae subsp. equisimilis bacteremia.
BMC INFECTIOUS DISEASES
(2023)
Review
Microbiology
Teresa Tavares, Liliana Pinho, Elva Bonifacio Andrade
Summary: Neonatal bacterial meningitis caused by Group B Streptococcus (GBS) is a severe disease associated with high mortality and neurological disability. Maternal colonization with GBS is the main risk factor for neonatal invasive disease. Despite preventive measures and improved neonatal care, the incidence and morbidity of GBS meningitis have not decreased. Many survivors suffer from complex neurological or neuropsychiatric sequelae.
CLINICAL MICROBIOLOGY REVIEWS
(2022)
Article
Infectious Diseases
Juan A. Quintero-Martinez, Joya-Rita Hindy, Said El Zein, Holenarasipur R. Vikram, Wendelyn Bosch, Daniel C. DeSimone, Larry M. Baddour
Summary: This study investigated the Viridans group streptococcal (VGS) isolates in patients with MVP endocarditis. The predominant species identified was S. mitis, and further evaluation of VGS species is recommended for risk profiling of infective endocarditis based on species identification.
INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES
(2023)
Article
Microbiology
Tristan Bohlman, Heith Waddell, Brant Schumaker
Summary: This article presents a new case of pneumonia and bacteremia caused by S. equi subsp. equi in a patient who was exposed to a horse with "Strangles" infection. The case highlights the importance of investigating S. equi subsp. equi exposures in rural areas, especially among individuals working with horses.
ANNALS OF CLINICAL MICROBIOLOGY AND ANTIMICROBIALS
(2023)
Article
Microbiology
Luis M. Jara, Jose Angulo-Tisoc, Luis G. Gimenez-Lirola, Ganwu Li, Roy Andrade, Javier Mamani
Summary: Streptococcus zooepidemicus is an emerging zoonotic pathogen causing severe lymphadenitis in guinea pigs in the Andean region. Molecular characterization revealed that this highly pathogenic strain possesses important virulence factors and is phylogenetically related to equines but distant from zoonotic and pig isolates reported in other countries.
Article
Biotechnology & Applied Microbiology
Siew Woh Choo, Waleed K. Mohammed, Naresh V. R. Mutha, Nadia Rostami, Halah Ahmed, Natalio Krasnogor, Geok Yuan Annie Tan, Nicholas S. Jakubovics
Summary: Cell-cell adhesion among oral bacteria, particularly Streptococcus gordonii and Streptococcus oralis, plays a crucial role in the development of polymicrobial communities like dental plaque. Gene regulation in response to coaggregation differs between S. gordonii and S. oralis, with specific genes involved in amino acid biosynthesis and transporters being upregulated. These distinct responses to coaggregation highlight the importance of understanding interspecies interactions in biofilm development and dental health maintenance.
APPLIED AND ENVIRONMENTAL MICROBIOLOGY
(2021)
