Article
Obstetrics & Gynecology
Lin-Ya Yang, Fang-Ju Lin, Aaron J. Katz, I. -Te Wang, Chung-Hsuen Wu
Summary: This study found no association between prenatal antidepressant use and the development of hypertensive disorders of pregnancy, but women taking higher cumulative doses of antidepressants were found to be at greater risk. Monitoring blood pressure more frequently or regularly in women on high cumulative doses of antidepressants may be necessary.
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY
(2021)
Article
Clinical Neurology
Beguem Irmak Oen, Xavier Vidal, Ursula Berger, Monica Sabate, Elena Ballarin, Olga Maisterra, Antonio San-Jose, Luisa Ibanez
Summary: The study found that in individuals aged 65 and older, current, recent, or past use of antidepressants was associated with significantly increased risk of stroke and mortality.
EUROPEAN JOURNAL OF NEUROLOGY
(2022)
Article
Clinical Neurology
Kelsey Kathleen Wiggs, Ayehsa C. Sujan, Martin E. Rickert, Patrick D. Quinn, Henrik Larsson, Paul Lichtenstein, Brian M. D'Onofrio, A. Sara Oberg
Summary: This study aimed to evaluate the risk of neonatal seizures and epilepsy in children born to women who use serotonergic antidepressants during pregnancy. The results showed that the children of women who reported using SSRIs/SNRIs during pregnancy had a higher risk of neonatal seizures and epilepsy compared to other children. However, after adjusting for various factors, this association was attenuated.
Article
Psychiatry
Yen-Hao Tran, Hieu K. Huynh, Marijke M. Faas, Stijn de Vos, Henk Groen
Summary: The study found that users of tricyclic antidepressants (TCAs) have an increased risk of developing preeclampsia and the late-onset subtype, while 5-HT2A antagonizing antidepressants may increase the risk of early-onset preeclampsia.
JOURNAL OF PSYCHIATRIC RESEARCH
(2022)
Article
Medicine, General & Internal
Salman Hussain, Ambrish Singh, Benny Antony, Jitka Klugarova, M. Hassan Murad, Aarthi S. Jayraj, Alena Langaufova, Miloslav Klugar
Summary: This study evaluates the association between the use of proton pump inhibitors (PPIs) and the risk of preeclampsia in pregnant women. The findings suggest that the use of PPIs during pregnancy significantly increases the risk of preeclampsia, although the increase is minimal in absolute terms. However, there is no evidence supporting that PPI use decreases the risk of preeclampsia or preterm preeclampsia.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Obstetrics & Gynecology
Hetti von Hellens, Leea Keski-Nisula, Heidi Sahlman
Summary: Maternal use of paracetamol during pregnancy is associated with the development of preeclampsia, potentially due to reverse causation.
BMC PREGNANCY AND CHILDBIRTH
(2021)
Review
Obstetrics & Gynecology
Cecilie Holm Christiansen, Stinne Hogh, Line Rode, Jeppe Bennekou Schroll, Hanne Kristine Hegaard, Hanne Trap Wolf
Summary: This systematic review and meta-analysis examined the association between multivitamin use and the risk of preeclampsia. The results showed very weak evidence suggesting that multivitamin use might reduce the risk of preeclampsia. However, due to limited and low-quality studies, further large-scale randomized controlled trials are needed to confirm these findings. Therefore, no final conclusions can be drawn regarding the preventive effect of multivitamin use in relation to preeclampsia based on the results of this review.
ACTA OBSTETRICIA ET GYNECOLOGICA SCANDINAVICA
(2022)
Article
Obstetrics & Gynecology
Anne Kvie Sande, Ingvild Dalen, Erik Andreas Torkildsen, Ragnar Kvie Sande, Nils-Halvdan Morken
Summary: This study investigated the factors affecting the risk of preeclampsia and found that type 1 and type 2 diabetes, chronic kidney disease, and chronic hypertension were more strongly associated with preterm preeclampsia.
ACTA OBSTETRICIA ET GYNECOLOGICA SCANDINAVICA
(2023)
Review
Medicine, General & Internal
Wiktor Wojczakowski, Zaneta Kimber-Trojnar, Filip Dziwisz, Magdalena Slodzinska, Hubert Slodzinski, Bozena Leszczynska-Gorzelak
Summary: In utero exposure to preeclampsia can lead to long-term cardiovascular effects in children, increasing the risk of hypertension, stroke, diabetes, and cardiovascular disease later in life. The mechanisms associated with cardiovascular disease appear to be a combination of genetic, molecular, and environmental factors, known as fetal and postnatal programming. Establishing a clear dependency mechanism between preeclampsia and cardiovascular disease is challenging due to its multifactorial nature.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Psychiatry
Haemy Chung, Kaitlin Hanken, Alicia K. Gerke, Brian C. Lund
Summary: This study found that discontinuation of existing montelukast therapy is unnecessary when initiating antidepressants. However, there may be evidence of depression relapse following montelukast initiation, which requires further investigation.
JOURNAL OF PSYCHOSOMATIC RESEARCH
(2023)
Article
Health Care Sciences & Services
Martin Ploderl, Simone Amendola, Michael Pascal Hengartner
Summary: This study investigated whether observational studies showing favorable results for antidepressants on suicidal behavior are more likely to be published in psychiatric journals and cited more often. The study found that studies with favorable results were more frequently published in psychiatric journals and were often conducted by authors with conflicts of interest. This may create a biased evidence base within psychiatry.
JOURNAL OF CLINICAL EPIDEMIOLOGY
(2023)
Article
Psychiatry
Carol Coupland, Paula Dhiman, Richard Morriss, Antony Arthur, Garry Barton, Julia Hippisley-Cox
Summary: This study investigated the association between long-term antidepressant use and adverse events. The findings showed that treatment with selective serotonin reuptake inhibitors (SSRIs) was associated with a decreased risk of diabetes and hypertension, but an increased risk of cardiovascular disease and all-cause mortality. Treatment with 'other' class antidepressants was associated with an increased risk of coronary heart disease, cardiovascular disease, and all-cause mortality.
Article
Medicine, General & Internal
Maxine R. Glanger, Gregory Peterson, Arun Abraham
Summary: Antidepressant drugs are commonly used in palliative care patients for managing psychiatric disorders and non-psychiatric symptoms, but discontinuation may cause distressing symptoms. We examined the risk of antidepressant discontinuation syndrome (ADDS) in palliative care patients, discussing strategies for reducing and managing it.
INTERNAL MEDICINE JOURNAL
(2021)
Article
Health Care Sciences & Services
Marija Majda Perisic, Klemo Vladimir, Sarah Karpov, Mario Storga, Ali Mostashari, Raya Khanin
Summary: Preeclampsia and gestational hypertensive disorders are common complications of pregnancy with long-term consequences. This study developed a risk score using machine learning to screen for GHD early. It confirmed that high BMI is a risk factor for GHD and explored the relationship between GHD and genetically constructed anthropometric measures and biomarkers.
JOURNAL OF PERSONALIZED MEDICINE
(2022)
Article
Psychiatry
Gianluca Serafini, Gustavo Vazquez, Fiammetta Monacelli, Matteo Pardini, Maurizio Pompili, Mario Amore
Summary: This study compared the socio-demographic and clinical features of bipolar disorder patients treated vs. not treated with antidepressant drugs (ADs). The results showed that patients treated with ADs were older, more likely to be retired, and more likely to have had a first major depressive episode. Patients receiving ADs also had more affective episodes and longer illness duration compared to those not treated with ADs.
PSYCHIATRY RESEARCH
(2021)