Article
Public, Environmental & Occupational Health
Mengjiao Huang, Matthew J. Strickland, Megan Richards, Joshua L. Warren, Howard H. Chang, Lyndsey A. Darrow
Summary: This study evaluates four epidemiologic designs commonly used to study acute associations between ambient temperature and preterm births. The results show that most designs can yield estimates unbiased by conception seasonality, but the time-stratified case-crossover design exhibits a small bias.
Article
Biology
Ernest O. Asare, Mohammad A. Al-Mamun, Monira Sarmin, A. S. G. Faruque, Tahmeed Ahmed, Virginia E. Pitzer
Summary: The study found that the seasonal pattern of rotavirus in Bangladesh shifted from biannual peaks to annual peaks in winter due to a declining birth rate. Meteorological factors also have an impact on the transmission rate of rotavirus before vaccination.
PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES
(2022)
Review
Medicine, General & Internal
Ioannis Mitrogiannis, Evangelos Evangelou, Athina Efthymiou, Theofilos Kanavos, Effrosyni Birbas, George Makrydimas, Stefania Papatheodorou
Summary: This study provides a summary of the evidence from meta-analyses of observational studies on risk factors associated with preterm birth (PTB). It identifies seven risk factors that are supported by robust evidence. The study suggests the need for routine screening of sleep quality and mental health during prenatal visits.
Review
Nutrition & Dietetics
Mangesh Deshmukh, Sanjay Patole
Summary: Probiotics have been shown to reduce the risk of necrotizing enterocolitis, late onset sepsis, and all-cause mortality in preterm neonates. Implementing routine probiotic supplementation can significantly improve outcomes in these vulnerable infants.
ADVANCES IN NUTRITION
(2021)
Review
Pediatrics
George Daskalakis, Alexandros Psarris, Antonios Koutras, Zacharias Fasoulakis, Ioannis Prokopakis, Antonia Varthaliti, Christina Karasmani, Thomas Ntounis, Ekaterini Domali, Marianna Theodora, Panos Antsaklis, Kalliopi I. Pappa, Angeliki Papapanagiotou
Summary: Preterm birth, a major public health concern worldwide, is the leading cause of neonatal morbidity and mortality. This review analyzes the association between infections and premature birth. Intrauterine infection/inflammation is commonly associated with spontaneous preterm birth. Inflammation-induced overproduction of prostaglandins can lead to uterine contractions and contribute to preterm delivery. Various pathogens, including Chlamydia trachomatis, Neisseria gonorrhoeae, Trichomonas vaginalis, Gardnerella vaginalis, Ureaplasma urealyticum, Mycoplasma hominis, Actinomyces, Candida spp., and Streptococcus spp., have been implicated in premature delivery, chorioamnionitis, and neonatal sepsis. Further research is needed to develop effective preventive methods and reduce neonatal morbidity.
Article
Health Care Sciences & Services
Deborah Bamber, Helen E. Collins, Charlotte Powell, Goncalo Campos Goncalves, Samantha Johnson, Bradley Manktelow, Jose Pedro Ornelas, Joao Correia Lopes, Artur Rocha, Elizabeth S. Draper
Summary: To study the long-term impact of very preterm birth, it is necessary to combine and harmonise data. In the RECAP Preterm project, a classification system has been developed and refined through consultations, allowing for better organization and analysis of data.
BMC MEDICAL RESEARCH METHODOLOGY
(2022)
Article
Pediatrics
Sara C. Handley, Elizabeth G. Salazar, Lucy T. Greenberg, Elizabeth E. Foglia, Scott A. Lorch, Erika M. Edwards
Summary: This study examines the delivery room management of moderate and late preterm infants. The study finds that the frequency of delivery room interventions decreases with increasing gestational age and varies across hospitals. The study also highlights the differing interpretation of resuscitation guidelines and the need for further research to improve evidence-based care for preterm infants in the delivery room.
Review
Pharmacology & Pharmacy
Hannah C. Zierden, Rachel L. Shapiro, Kevin DeLong, Davell M. Carter, Laura M. Ensign
Summary: Preterm birth is defined as delivery before 37 weeks of gestation, with 15 million infants born prematurely globally each year, increasing the risk of mortality and health challenges. While the only FDA approved therapy for preventing preterm birth in the U.S. has faced recent setbacks, interdisciplinary efforts are underway to develop next generation therapies to prevent preterm birth and save infant lives. This research aims to better identify women at risk for preterm birth, prevent premature labor, and ultimately improve outcomes for newborns.
ADVANCED DRUG DELIVERY REVIEWS
(2021)
Review
Clinical Neurology
Ayman Saleh, Matthew King, Jane Hamilton, Teresa Pigott, Rania Elkhatib, Asim Shah, Salih Selek
Summary: The study found no association between birth season or months with schizophrenia or bipolar disorder among hospitalized patients. Severe schizophrenia requiring admission may not be related to birth seasonality. Limitations include retrospective design, inability to control for environmental factors, and recruiting from a single location.
JOURNAL OF AFFECTIVE DISORDERS
(2021)
Article
Psychiatry
Lucy D. Vanes, Robin M. Murray, Chiara Nosarti
Summary: Preterm birth is associated with an elevated risk of developmental and adult psychiatric disorders, including psychosis, which can be attributed to abnormal brain development and alterations in brain structure and function.
SCHIZOPHRENIA RESEARCH
(2022)
Article
Medicine, General & Internal
Teresa Janevic, Kimberly B. Glazer, Luciana Vieira, Ellerie Weber, Joanne Stone, Toni Stern, Angela Bianco, Brian Wagner, Siobhan M. Dolan, Elizabeth A. Howell
Summary: This study found no evidence for increased racial/ethnic disparities in preterm birth in New York City during the early stages of the COVID-19 pandemic, regardless of whether women tested positive or negative for SARS-CoV-2.
Article
Medicine, General & Internal
Heli Tiensuu, Antti M. Haapalainen, Pinja Tissarinen, Anu Pasanen, Tomi A. Maatta, Johanna M. Huusko, Steffen Ohlmeier, Ulrich Bergmann, Marja Ojaniemi, Louis J. Muglia, Mikko Hallman, Mika Ramet
Summary: This study aimed to identify placental proteins associated with spontaneous preterm birth. We found rare damaging variants in the SERPINA1 gene in families with recurrent spontaneous preterm deliveries. The protein and mRNA levels of alpha-1 antitrypsin/SERPINA1 were downregulated in spontaneous preterm births, and it played a role in regulating actin cytoskeleton pathway, Slit-Robo signaling, and extracellular matrix organization. Loss of the protease inhibition effects of alpha-1 antitrypsin may render structures critical to maintaining pregnancy susceptible to proteases and inflammatory activation, leading to spontaneous premature birth.
Article
Immunology
Marisa R. Young, Carly Broadwell, Deborah Kacanek, Ellen G. Chadwick, Jennifer Jao, Anna-Barbara Moscicki, Kathleen Powis, Katherine Tassiopoulos, Lynn M. Yee, Lisa B. Haddad
Summary: The prevalence of sexually transmitted infections is high among pregnant individuals living with HIV. Coinfection is not associated with the risk of preterm birth. One-third of the individuals have missing data on Trichomonas vaginalis, indicating the need for interventions to promote guideline-driven screening. Sexually transmitted infections diagnosed during pregnancy among people living with HIV are not associated with the risk of preterm birth.
CLINICAL INFECTIOUS DISEASES
(2022)
Review
Pediatrics
Jayne Trickett, Catherine Hill, Topun Austin, Samantha Johnson
Summary: This review discusses the development and measurement of sleep during the neonatal period, the impact of preterm birth on sleep, and the interaction between sleep, cognition, and social-emotional outcomes.
Article
Clinical Neurology
Xi Chen, Xiaoli Zhang, Wenhua Li, Wendong Li, Yong Wang, Shan Zhang, Changlian Zhu
Summary: Preterm births with different etiologies are associated with varying neonatal complications, but no differences in neurodevelopmental outcomes were observed at 12 months of corrected age.
FRONTIERS IN NEUROLOGY
(2021)
Editorial Material
Pediatrics
Janet D. Cragan, Bessie A. Young, Adolfo Correa
JOURNAL OF PEDIATRICS
(2015)
Article
Hematology
Natalie A. Bello, Hyacinth I. Hyacinth, Nicholas S. Roetker, Samantha R. Seals, Rakhi P. Naik, Vimal K. Derebail, Abhijit V. Kshirsagar, Nigel S. Key, James G. Wilson, Adolfo Correa, Robert J. Adams, Leonard D. Egede, W. T. Longstreth, Gaurav Choudhary, Beatrice E. Gee, Austin L. Hughes, Amil M. Shah, Joann E. Manson, Matthew Allison, Gregory L. Burke, Aaron R. Folsom, Cara L. Carty, Alexander P. Reiner, Scott D. Solomon, Suma H. Konety
Article
Public, Environmental & Occupational Health
Brandon J. Auerbach, Ronit Katz, Katherine Tucker, Edward J. Boyko, Adam Drewnowski, Alain Bertoni, Patricia Dubbert, DeMarc A. Hickson, Adolfo Correa, Bessie A. Young
PREVENTIVE MEDICINE
(2017)
Article
Cardiac & Cardiovascular Systems
Matthew E. Oster, Christopher H. Kim, Aaron S. Kusano, Janet D. Cragan, Paul Dressler, Alice R. Hales, William T. Mahle, Adolfo Correa
AMERICAN JOURNAL OF CARDIOLOGY
(2014)
Article
Multidisciplinary Sciences
Ranee Chatterjee, Clemontina A. Davenport, Laura M. Raffield, Nisa Maruthur, Leslie Lange, Elizabeth Selvin, Kenneth Butler, Hsin-Chieh Yeh, James G. Wilson, Adolfo Correa, David Edelman, Elizabeth Hauser
Article
Urology & Nephrology
Stanford E. Mwasongwe, Rikki M. Tanner, Bharat Poudel, Daniel N. Pugliese, Bessie A. Young, Marwah Abdalla, Solomon K. Musani, Orlando M. Gutierrez, Adolfo Correa, Daichi Shimbo, Paul Muntner
CLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
(2020)
Article
Cardiac & Cardiovascular Systems
Akihiro Nomura, Connor A. Emdin, Hong Hee Won, Gina M. Peloso, Pradeep Natarajan, Diego Ardissino, John Danesh, Heribert Schunkert, Adolfo Correa, Matthew J. Bown, Nilesh J. Samani, Jeanette Erdmann, Ruth McPherson, Hugh Watkins, Danish Saleheen, Roberto Elosua, Masa-aki Kawashiri, Hayato Tada, Namrata Gupta, Svati H. Shah, Daniel J. Rader, Stacey Gabriel, Amit V. Khera, Sekar Kathiresan
CIRCULATION-GENOMIC AND PRECISION MEDICINE
(2020)
Article
Cardiac & Cardiovascular Systems
Matthew W. Segar, Byron C. Jaeger, Kershaw Patel, Vijay Nambi, Chiadi E. Ndumele, Adolfo Correa, Javed Butler, Alvin Chandra, Colby Ayers, Shreya Rao, Alana A. Lewis, Laura M. Raffield, Carlos J. Rodriguez, Erin D. Michos, Christie M. Ballantyne, Michael E. Hall, Robert J. Mentz, James A. de Lemos, Ambarish Pandey
Summary: The study utilized machine learning to develop race-specific heart failure risk prediction models and identified natriuretic peptide levels as the most important predictor of heart failure risk across races. Additionally, troponin levels in Black individuals and ECG-based Cornell voltage in White individuals were significant predictors of heart failure risk. There were distinct differences in heart failure risk factors between different races.
Article
Peripheral Vascular Disease
Arnaud D. Kaze, Solomon K. Musani, Aurelian Bidulescu, Adolfo Correa, Alain G. Bertoni, Rexford S. Ahima, Sherita H. Golden, Marwah Abdalla, Justin B. Echouffo-Tcheugui
Summary: This study found an association between plasma leptin levels and blood pressure progression in Blacks, suggesting that leptin concentrations may help identify individuals at risk for hypertension and guide prevention and management strategies.
Article
Multidisciplinary Sciences
Vladimir B. Seplyarskiy, Ruslan A. Soldatov, Evan Koch, Ryan J. McGinty, Jakob M. Goldmann, Ryan D. Hernandez, Kathleen Barnes, Adolfo Correa, Esteban G. Burchard, Patrick T. Ellinor, Stephen T. McGarvey, Braxton D. Mitchell, Ramachandran S. Vasan, Susan Redline, Edwin Silverman, Scott T. Weiss, Donna K. Arnett, John Blangero, Eric Boenvinkle, Jiang He, Courtney Montgomery, D. C. Rao, Jerome I. Rotter, Kent D. Taylor, Jennifer A. Brody, Yii-Der Ida Chen, Lisa de las Fuentes, Chii-Min Hwu, Stephen S. Rich, Ani W. Manichaiku, Josyf C. Mychaleckyj, Nicholette D. Palmer, Jennifer A. Smith, Sharon L. R. Kardia, Patricia A. Peyser, Lawrence F. Bielak, Timothy D. O'Connor, Leslie S. Emery, Christian Gilissen, Wendy S. W. Wong, Peter V. Kharchenko, Shamil Sunyaev
Summary: The study utilized nonnegative matrix factorization to uncover the biological mechanisms of human germline mutations. Analysis of a sequencing dataset revealed nine processes explaining the variation in mutation properties between loci, including bulky DNA lesions, replication direction and timing, among others. This research identified mutagenic effects of active demethylation, long interspersed nuclear elements, and a specific mutagenic process in oocytes.
Article
Cardiac & Cardiovascular Systems
Vishal N. Rao, Christopher G. Bush, Morgana Mongraw-Chaffin, Michael E. Hall, Donald Clark, Marat Fudim, Adolfo Correa, Bradley G. Hammill, Emily O'Brien, Yuan- Min, Robert J. Mentz
Summary: In a group of Black participants, high pericardial adipose tissue and visceral adipose tissue were associated with incident heart failure and heart failure with preserved ejection fraction, while only pericardial adipose tissue was associated with mortality.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2021)
Article
Clinical Neurology
Zsuzsanna Ament, Amit Patki, Ninad Chaudhary, Varun M. Bhave, Ana-Lucia Garcia Guarniz, Yan Gao, Robert E. Gerszten, Adolfo Correa, Suzanne E. Judd, Mary Cushman, D. Leann Long, M. Ryan Irvin, W. Taylor Kimberly
Summary: This study identified novel metabolites associated with stroke risk and suggested that the relationship between nucleoside levels and stroke risk is more influenced by environmental factors than genetic variation.
Article
Health Care Sciences & Services
Pramod Anugu, Md Abu Yusuf Ansari, Yuan - Min, Emelia J. Benjamin, Joanne Murabito, Karen Winters, Erica Turner, Adolfo Correa
Summary: This study contributes to the knowledge regarding the feasibility of conducting cardiovascular disease research using mobile health platforms among middle-aged and older African Americans. The findings highlight the need to reduce the age and education divide in access and use of internet and smartphones for tracking health and research in African American communities.
JOURNAL OF MEDICAL INTERNET RESEARCH
(2022)
Article
Health Care Sciences & Services
Shandria Sutton, Mario Sims, Karen Winters, Adolfo Correa, Cam Escoffery, Kimberly Jacob Arriola
Summary: This study examines the association between cardiovascular health and the use of internet and mobile technology (IMT) among older African Americans. The findings show that there is no overall association between cardiovascular health and IMT use, except for the use of other smart devices. However, specific metrics of cardiovascular health, such as blood pressure, body mass index, cholesterol, and physical activity, are associated with different aspects of IMT use.
TELEMEDICINE AND E-HEALTH
(2023)
Letter
Urology & Nephrology
Alexander P. Reiner, Laura M. Raffield, Nora Franceschini, Paul L. Auer, Ethan M. Lange, Deborah A. Nickerson, Neil A. Zakai, Adolfo Correa, Nels Olson
CLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
(2021)