Article
Respiratory System
Hans Bisgaard, Marianne Mikkelsen, Morten Arendt Rasmussen, Astrid Sevelsted, Ann-Marie Malby Schoos, Nicklas Brustad, Anders U. Eliasen, Jonathan Thorsen, Bo Chawes, Goezde Guerdeniz, Andreanne Morin, Ken Stark, Jakob Stokholm, Carole Ober, Casper Emil Tingskov Pedersen, Klaus Bonnelykke
Summary: Fish-oil supplementation during pregnancy reduces the risk of persistent wheeze or asthma in the child. It has protective effects on non-atopic asthma and infections, but the effects on atopic asthma depend on maternal genotype and n-3 LCPUFA levels.
Article
Dermatology
Anna M. Andersson, Hannah Kaiser, Lone Skov, Anders Koch, Jacob P. Thyssen
Summary: The overall prevalence of physician-diagnosed atopic dermatitis in Greenlandic children aged 0-7 years is 35%, indicating a high prevalence and a likely increase over the past 20 years. Atopic dermatitis is significantly associated with Inuit descent, parental atopic disposition, and higher socioeconomic status.
CLINICAL AND EXPERIMENTAL DERMATOLOGY
(2023)
Article
Genetics & Heredity
Chuiji Chen, Le Su, Wenhao Duan, Yansen Zheng, Dianzhong Zhang, Yucai Wang
Summary: This study used bidirectional two-sample Mendelian randomization to find a causal relationship between asthma/AD and rheumatoid arthritis, but no causal relationship was found between rheumatoid arthritis and asthma/AD.
BMC MEDICAL GENOMICS
(2023)
Article
Allergy
Sara Gerday, Florence Schleich, Monique Henket, Francoise Guissard, Virginie Paulus, Renaud Louis
Summary: This study compared atopic and non-atopic asthmatics and found differences in demographics, functional characteristics, and inflammatory profiles. While atopic asthmatics showed a consistent eosinophilic pattern, non-atopic asthmatics exhibited neutrophilic inflammation before the age of 50 and eosinophilic inflammation above 50 years old.
WORLD ALLERGY ORGANIZATION JOURNAL
(2022)
Article
Allergy
Taina K. Lajunen, Jouni J. K. Jaakkola, Maritta S. Jaakkola
Summary: Smoking has different effects on the risks of atopic and non-atopic asthma, with women at greater risk of atopic asthma even with low levels of smoking. After quitting smoking, the risk of non-atopic asthma continues for a longer period, especially in men. Gender plays a role in modifying these effects.
CLINICAL AND TRANSLATIONAL ALLERGY
(2021)
Article
Dermatology
Qiang Liu, Li Chen, Yipeng Wang, Xiangyu Wang, Sarah J. Lewis, Jing Wang
Summary: Using genetic associations and large study data sets, the study found no strong evidence of a causal link between atopic dermatitis and overall cancer risk.
JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY
(2023)
Article
Multidisciplinary Sciences
Seung Won Lee, Jiwon Park, Hayeon Kim, Yong Woo Jung, Yoo Sang Baek, Yejee Lim, Kyungim Kim
Summary: This nationwide matched cohort study found that atopic dermatitis (AD) is associated with an increased risk of gastroesophageal reflux disease (GERD). Appropriate management should be considered in adults with AD to prevent GERD.
Article
Pharmacology & Pharmacy
Huimin Yuan, Yan Sun, Shujing Zhang, Jing Feng, Zijiao Tian, Jingang Liu, Hang Wang, Yushan Gao, Yang Tang, Fengjie Zheng
Summary: This study explored the relationship between mental disorders and neuroinflammatory response in atopic dermatitis (AD). Using an AD mouse model, it was found that the expression of neuroinflammatory factors in the hippocampus significantly increased, further revealing the underlying mechanism of mental disorders in AD. Reducing neuroinflammation and improving mental disorders may be an important approach to promote AD recovery.
FRONTIERS IN PHARMACOLOGY
(2022)
Article
Medicine, General & Internal
Gulsah Duyuler Aycin
Summary: Asthma is a heterogeneous disease with various clinical phenotypes in children and adults, with allergic asthma being a common subtype. By comparing clinical features, asthma severity, eosinophil count, and total IgE values in atopic and non-atopic asthma patients, tailored treatment options can be better determined for children with asthma.
ACTA MEDICA MEDITERRANEA
(2021)
Article
Nutrition & Dietetics
Athanasia Tragomalou, George Paltoglou, Maria Manou, Ioannis V. Kostopoulos, Sofia Loukopoulou, Maria Binou, Ourania E. Tsitsilonis, Flora Bacopoulou, Penio Kassari, Marina Papadopoulou, George Mastorakos, Evangelia Charmandari
Summary: Obesity in adolescence is linked to cardiovascular disease. Non-traditional risk factors can be used as biomarkers to predict future CVD. Lifestyle intervention programs can improve these risk factors.
Review
Medicine, General & Internal
Angela Klain, Giulio Dinardo, Alessandra Salvatori, Cristiana Indolfi, Marcella Contieri, Giulia Brindisi, Fabio Decimo, Anna Maria Zicari, Michele Miraglia del Giudice
Summary: Non-allergic asthma in childhood is less common, but it is crucial to identify the causes in order to control asthma, especially for patients not responding to conventional treatments.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Oncology
Anqi Wang, Peggy Wan, James R. Hebert, Loic Le Marchand, Lynne R. Wilkens, Christopher A. Haiman
Summary: A study on diverse racial/ethnic populations found that atopic allergic conditions (AACs) were not associated with prostate cancer (PCa) incidence, but were inversely associated with PCa mortality, suggesting a potential role in reducing tumour progression.
BRITISH JOURNAL OF CANCER
(2023)
Article
Pediatrics
Louise Mandrup Bach, Sune Rubak, Adam Holm-Weber, Julie Prahl, Mette Hermansen, Kirsten Skamstrup Hansen, Bo Chawes
Summary: This study aimed to determine the risk factors for non-adherence to asthma treatment in preschool children. The study found that 75% of children under 6 years old diagnosed with asthma were not adherent to their medication. Increasing adherence was associated with co-existing allergies and experiencing loss of control events, while lower adherence was associated with atopic predisposition.
Review
Cardiac & Cardiovascular Systems
Rong Zeng, Jing Wang, Ziting Liang, Jintao Zhang, Zihan Wang, Changjuan Xu, Liang Dong
Summary: This meta-analysis demonstrated that patients with atopic diseases, especially asthma, have a higher risk of developing atrial fibrillation.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2022)
Article
Respiratory System
Bronwyn Brew, Alison Gibberd, Guy B. Marks, Natalie Strobel, Clare Wendy Allen, Louisa Jorm, Georgina Chambers, Sandra Eades, Bridgette McNamara
Summary: This study identified potentially preventable risk factors for hospitalised asthma in Australian Aboriginal children, with risk factors including hospitalisation for acute respiratory tract infection, area-level disadvantage, prematurity, and low birth weight. Improving care for pregnant Aboriginal women and Aboriginal infants with ARTI may help reduce the burden of asthma in the Indigenous population.
