期刊
ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY
卷 31, 期 10, 页码 2345-2353出版社
WILEY
DOI: 10.1002/etc.1955
关键词
Organophosphate; Feeding study; Reptile; Ecological risk assessment; Terrestrial ecotoxicology
资金
- FEDER through COMPETE-Programa Operacional Factores de Competitividade
- national funding through Fundacao para a Ciencia e Tecnologia (FCT) [FCTPTDC/AMB/64497/2006]
- FCT [SFRH/BD/31470/2006]
- Fundação para a Ciência e a Tecnologia [SFRH/BD/31470/2006, PTDC/AMB/64497/2006] Funding Source: FCT
In Europe, reptiles have been recently included in environmental risk-assessment processes for registration of plant-protection products. However, data on toxicity effects of most compounds are lacking. Chlorpyrifos is the most commonly used organophosphorus insecticide worldwide. In the present study, the authors exposed a lacertid lizard, Podarcis bocagei, to sublethal concentrations of chlorpyrifos. Individuals were exposed through spiked food for a period of 20 d (low dose 0.12?mg/kg/d, high dose 1.57?mg/kg/d). After exposure, various biomarkers of exposure and effect were evaluated, including the activities of glutathione S-transferase and enzymes involved in the glutathione redox cycle, glutathione concentrations, activities of esterases, liver and testes histopathologies, as well as locomotory and predatory behavior. The results indicate that sublethal, subchronic exposure to chlorpyrifos can affect P. bocagei in a dose-dependent manner. Adverse effects occurred at both the subindividual and individual levels, including inhibition of carboxylesterases and cholinesterases (ChEs), liver histopathological changes, and altered predatory behaviors. Animals exposed to chlorpyrifos took more time to capture and subdue prey items. The results suggest a link between effects at subindividual levels of organization with those observed at the whole individual level after exposure to environmentally realistic dosages of chlorpyrifos. Environ. Toxicol. Chem. 2012; 31: 23452353. (c) 2012 SETAC
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据