Review
Pathology
James S. Castleman, Elizabeth Wall, Stephanie Allen, Denise Williams, Samantha Doyle, Mark D. Kilby
Summary: Prenatal exome sequencing provides a rapid genetic diagnosis for fetuses with structural anomalies, improving counseling, decision-making, and management during pregnancy. This novel investigation has a diagnostic rate of over 10% in carefully selected cases, with a potential range of 6% to 80% for certain phenotypes where conventional tests have not detected a diagnosis. Expert oversight and multidisciplinary teamwork are crucial for ensuring high-quality care and accurate counseling for patients undergoing prenatal exome sequencing.
EXPERT REVIEW OF MOLECULAR DIAGNOSTICS
(2021)
Article
Multidisciplinary Sciences
Kevin Yu, Michelle Rodriguez, Zubin Paul, Elizabeth Gordon, Tongjun Gu, Kelly Rice, Eric W. Triplett, Maureen Keller-Wood, Charles E. Wood
Summary: Recent evidence suggests bacterial DNA and protein can enter the fetus from the maternal bloodstream, and now the importance of bacterial transmission from the maternal mouth to the fetus has been discovered. Through inoculating maternal sheep using three different methods, it was found that the oral route is effective for transmitting bacterial cellular components to the fetus.
SCIENTIFIC REPORTS
(2021)
Review
Genetics & Heredity
Alexandra Emms, James Castleman, Stephanie Allen, Denise Williams, Esther Kinning, Mark Kilby
Summary: Congenital malformations diagnosed by ultrasound screening have an underlying genetic cause in many cases. Next generation sequencing as a secondary prenatal genetic test offers additional diagnostic yield for congenital abnormalities potentially associated with genetic causes, especially in cases involving cardiac and neurological anomalies, large nuchal translucency, and non-immune fetal hydrops. The use of exome sequencing has shown significant incremental yield in single-system anomalies, making it a valuable tool for routine clinical care in fetuses with congenital abnormalities.
Article
Surgery
Robert Bergholz, Thomas Krebs, Birte Cremieux, Carla Georgi, Felipe Fromm, Michael Boettcher, Thomas Andreas, Bastian Tiemann, Katharina Wenke, Konrad Reinshagen, Kurt Hecher
Summary: This report summarizes a pilot study in an ovine model for prenatal treatment of gastroschisis, focusing on fetal bag insertion, intestinal bag placement, and bag fixation. Results show technical challenges and limitations in anchoring the bag to the fetus permanently, indicating the need for further development of specially designed instruments, bags, and fixation methods.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2021)
Article
Pediatrics
Xu Li, Hui Hui Lin, Ke Fei Hu, Yun Peng
Summary: This study investigated the MRI findings of fetal abdominal or sacrococcygeal teratomas and parasitic fetuses and analyzed the outcomes based on follow-up assessments. The MRI data of 60 cases were examined, and the results were compared with prenatal diagnoses. The study found that MRI has a high accuracy rate in diagnosing fetal sacrococcygeal teratomas and parasitic fetuses, and the prognosis is generally good.
FRONTIERS IN PEDIATRICS
(2023)
Article
Obstetrics & Gynecology
Laura D. Brown, Claire Palmer, Lucas Teynor, Brit H. Boehmer, Jane Stremming, Eileen Chang, Alicia White, Amanda K. Jones, Sarah N. Cilvik, Stephanie R. Wesolowski, Paul J. Rozance
Summary: The study found that fetal sex does not have a widespread impact on experimental insults, with most outcomes showing no gender-based differences. The only exceptions were higher hormone concentrations in female fetuses.
REPRODUCTIVE SCIENCES
(2022)
Review
Medicine, General & Internal
Fujiao He, Yaqin Wang, Yun Xiu, Yixin Zhang, Lizhu Chen
Summary: The application of AI in prenatal ultrasound has resulted in significant advancements, improving work efficiency, providing quantitative assessments, standardizing measurements, enhancing diagnostic accuracy, and automating image quality control. However, these applications also face challenges that need to be addressed.
FRONTIERS IN MEDICINE
(2021)
Article
Obstetrics & Gynecology
Kaihui Zeng, Dongmei Li, Yao Zhang, Chengcheng Cao, Ruobing Bai, Zeyu Yang, Lizhu Chen
Summary: Congenital megaduodenum is a rare disorder that can be a differential diagnosis for massive fetal abdominal cystic masses. Ultrasound examinations showing communication between the mass and the stomach can help in determining the diagnosis.
BMC PREGNANCY AND CHILDBIRTH
(2021)
Article
Endocrinology & Metabolism
Alicia White, Jane Stremming, Brit H. Boehmer, Eileen I. Chang, Sonnet S. Jonker, Stephanie R. Wesolowski, Laura D. Brown, Paul. J. Rozance
Summary: After a 1-week infusion of IGF-1 LR3, late gestation fetal sheep showed lower plasma insulin and glucose concentrations, reduced fetal glucose-stimulated insulin secretion, and decreased fractional insulin secretion from isolated fetal islets without changes in pancreatic insulin content.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
(2021)
Article
Agriculture, Dairy & Animal Science
Maria Grazia Cappai, Petra Wolf, Annette Liesegang, Giovanni Paolo Biggio, Andrea Podda, Antonio Varcasia, Claudia Tamponi, Fiammetta Berlinguer, Ignazio Cossu, Walter Pinna, Raffaele Cherchi
Summary: Monitoring serum protein fraction (SPF) levels, including metabolic profiling, in pregnant jennies can provide insights into the overall health status of the mother. Adequate dietary nutrient supplementation during mid-gestation is crucial to prevent homeostasis perturbation of jennies.
Review
Pediatrics
Zhengqiang Cang, Jiangbo Cui, Jiaomiao Pei, Zheng Wang, Yichen Du, Siqi Mu, Wenjie Dou, Xing Fan, Xi Zhang, Yang Li
Summary: This systematic review analyzed different diagnostic techniques for micrognathia and summarized consistent diagnostic criteria. A total of 30 biometric parameters related to the mandible were identified, and 15 of them can provide simple and convenient diagnostic criteria or warning value for micrognathia.
FRONTIERS IN PEDIATRICS
(2023)
Review
Physiology
Miguel Sanchez-Polan, Evelia Franco, Cristina Silva-Jose, Javier Gil-Ares, Javier Perez-Tejero, Ruben Barakat, Ignacio Refoyo
Summary: This study analyzed 15 studies on the impact of exercise during pregnancy on prenatal depression and depressive symptoms, finding a negative association between moderate exercise and prenatal depression, while inactive pregnant women had a higher risk of prenatal depression. Therefore, supervised exercise during pregnancy may be beneficial for preventing and reducing prenatal depression and depressive symptoms.
FRONTIERS IN PHYSIOLOGY
(2021)
Editorial Material
Green & Sustainable Science & Technology
Shahana Althaf
Summary: A study combining material flow and geospatial analysis presents viable strategies for integrating e-waste pathways with virgin mining to build sustainable metal supply chains.
NATURE SUSTAINABILITY
(2023)
Article
Agriculture, Dairy & Animal Science
Cassandra M. Herring, Fuller W. Bazer, Gregory A. Johnson, Heewon Seo, Shengdi Hu, Mohammed Elmetwally, Wenliang He, Daniel B. Long, Guoyao Wu
Summary: Supplementing L-arginine (Arg) during early gestation in gilts improves the survival and development of conceptuses. This is achieved by increasing the number of viable fetuses, enhancing placental blood vessel development, improving embryonic survival, increasing placental weight and fetus weight, and promoting the growth of amniotic and allantoic fluids. Arg supplementation also stimulates the syntheses of nitric oxide (NO) and polyamines in the placenta, increases the transportation of water and amino acids, and upregulates the expression of angiogenic factors and aquaporins.
JOURNAL OF ANIMAL SCIENCE AND BIOTECHNOLOGY
(2022)
Article
Environmental Sciences
Junghee Joo, Eilhann E. Kwon, Jechan Lee
Summary: Many aspects of modern life are associated with using electrical and electronic devices, leading to a tremendous amount of electronic waste. Challenges in managing and treating E-waste have arisen due to the lack of proper technologies. Pyrolysis process can effectively treat complex waste materials, but its industrialization is hindered by high costs.
ENVIRONMENTAL POLLUTION
(2021)
Article
Environmental Sciences
Ruikun Hou, Xia Huo, Shaocheng Zhang, Cheng Xu, Yu Huang, Xijing Xu
SCIENCE OF THE TOTAL ENVIRONMENT
(2020)
Article
Environmental Sciences
Xiangbin Zheng, Xijin Xu, Fangfang Lu, Qihua Wang, Zhijun Zeng, Xia Huo
Summary: This study analyzed the associations among blood Pb and Cd, Th1/Th2 cytokines, and IgG subclasses in children living in electronic waste areas. The results show that heavy metal exposure, particularly Pb, may affect IgG subclass production by regulating Th1/Th2 cytokines in exposed children.
SCIENCE OF THE TOTAL ENVIRONMENT
(2021)
Article
Environmental Sciences
Qihua Wang, Xijin Xu, Zhijun Zeng, Machteld N. Hylkema, Zongwei Cai, Xia Huo
ENVIRONMENT INTERNATIONAL
(2020)
Article
Materials Science, Multidisciplinary
T. B. Asafa, R. A. Odediji, T. O. Salaudeen, A. Lateef, M. O. Durowoju, M. A. Azeez, T. A. Yekeen, I. C. Oladipo, H. M. Irshad, S. H. Abbas
Summary: This study demonstrated that a paint mixture containing 0.175 wt% of both AgNPs and EPW exhibited optimal physical and mechanical properties, with a 16% decrease in specific gravity, a 30% increase in hiding power/opacity, and a 236% enhancement in abrasion strength. Comparisons with other nanoparticles, such as ZnO and Fe2O3, showed that AgNPs required lower concentration to achieve greater effects. The findings of this study will benefit the paint industry in maximizing the advantages of nanotechnology.
BULLETIN OF MATERIALS SCIENCE
(2021)
Article
Environmental Sciences
Xiang Zeng, Cheng Xu, Xijin Xu, Yu Zhang, Yu Huang, Xia Huo
Summary: The study revealed that in e-waste-exposed areas, there is a correlation between children's blood lead levels and behavioral health, with higher blood lead levels linked to increased risk of behavioral problems, and lower NPY levels associated with higher risk of behavioral difficulties.
Article
Environmental Sciences
Zihan Chen, Xia Huo, Shaocheng Zhang, Zhiheng Cheng, Yu Huang, Xijin Xu
Summary: The study showed that children exposed to e-waste have smaller left ventricles and impaired systolic function, which is associated with chronic low-grade inflammation and elevated blood lead levels.
Article
Environmental Sciences
Xiuli Luo, Xia Huo, Yuling Zhang, Zhiheng Cheng, Shuqin Chen, Xijin Xu
Summary: The study revealed that children exposed to lead had higher levels of blood Pb and plasma endotoxin, increased intestinal permeability, lower physical growth levels, poorer gut health, and elevated peripheral inflammatory indices. These results indicate the potential negative impact of environmental lead exposure on children's intestinal health.
Review
Environmental Sciences
Zihan Chen, Xia Huo, Guangcan Chen, Xiuli Luo, Xijin Xu
Summary: Lead, a heavy metal widely used in industry, is also a common environmental contaminant with toxicological consequences on many species. It adversely affects the cardiovascular system in humans, potentially leading to heart failure, pressure overload, arrhythmia, myocardial ischemia, and cardiotoxicity. Research indicates that lead exposure may play a significant role in the occurrence and development of heart failure.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2021)
Review
Engineering, Environmental
Okunola A. Alabi, Yetunde M. Adeoluwa, Xia Huo, Xijin Xu, Adekunle A. Bakare
Summary: Recently, electronic waste has become the fastest growing waste stream globally, posing potential environmental and public health hazards due to hazardous constituents. More studies are needed to clarify the dangers posed by e-waste constituents on both the environment and public health.
JOURNAL OF ENVIRONMENTAL HEALTH SCIENCE AND ENGINEERING
(2021)
Article
Environmental Sciences
Guangcan Chen, Xia Huo, Xiuli Luo, Zhiheng Cheng, Yuling Zhang, Xijin Xu
Summary: Research findings indicate that exposure to polycyclic aromatic hydrocarbon (PAH) pollutants in e-waste areas can significantly impact the intestinal mucosal immunity of children, leading to changes in immune responses such as increased SLA levels, white blood cell counts, decreased CD4(+) T cell percentage, and higher risk of diarrhea. Specific PAH compounds were found to be correlated with different immune markers, with OH-PAH concentrations negatively affecting child growth and certain PAH compounds positively impacting secretory immunoglobulin A levels.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2021)
Review
Environmental Sciences
Zhijun Zeng, Sieglind Ngai, Qihua Wang, Wanting Liang, Xia Huo
Summary: Early-life exposure to environmental toxicants, such as organic pollutants, heavy metals, and air pollutants, can adversely affect human health, particularly the immunotoxicity. Studies have shown that exposure to these toxicants is associated with decreased potency of antibodies produced from childhood immunizations, leading to overall deficiency in vaccines' provided protection. Changes in humoral immune-related tissue/cells/molecules response to vaccines induced by toxicant exposure appear to play a predominant role in the inverse associations between vaccine antibody responsiveness and environmental toxicants.
SCIENCE OF THE TOTAL ENVIRONMENT
(2021)
Article
Environmental Sciences
Xueling Lu, Eliza Fraszczyk, Thomas P. van der Meer, Martijn van Faassen, Vincent W. Bloks, Ido P. Kema, Andre P. van Beek, Shuang Li, Lude Franke, Harm-Jan Westra, Xijin Xu, Xia Huo, Harold Snieder, Bruce H. R. Wolffenbuttel, Jana V. van Vliet-Ostaptchouk
ENVIRONMENT INTERNATIONAL
(2020)
Review
Environmental Sciences
Attila Csaba Kondor, Anna Viktoria Vancsik, Laszlo Bauer, Lili Szabo, Zoltan Szalai, Gergely Jakab, Gabor Maasz, Marta Pedrosa, Maria Jose Sampaio, Ana Rita Lado Ribeiro
Summary: This review provides a critical overview of research on the removal efficiency of priority substances and compounds of emerging concern through bank filtration, discussing influencing factors and future challenges. The findings show that the efficiency of bank filtration is influenced by multiple factors and varies for different substances.
ENVIRONMENTAL POLLUTION
(2024)
Article
Environmental Sciences
Xinyan Wang, Shuai Zhang, Huihui Yan, Zhao Ma, Yunshan Zhang, Haining Luo, Xueli Yang
Summary: This study investigated the association between ambient PM2.5, O3 pollution, and ovarian reserve in reproductive-aged Chinese women. The results showed that increased exposure to PM2.5 and O3 was associated with decreased AMH levels, indicating reduced ovarian reserve. Notably, the effects of O3 exposure on ovarian reserve were different from those of PM2.5 exposure.
ENVIRONMENTAL POLLUTION
(2024)
Article
Environmental Sciences
Tingting Ma, Yanjuan Ding, Fengjiao Xu, Chen Zhang, Min Zhou, Ya Tang, Yanrong Chen, Yating Wen, Rufei Chen, Bin Tang, Shigui Wang
Summary: The dragonfly species Orthetrum albistylum can accumulate heavy metals, and its heat shock protein genes have the potential to serve as biomarkers for monitoring environmental pollutants.
ENVIRONMENTAL POLLUTION
(2024)
Article
Environmental Sciences
Naoto Ishiwaka, Koya Hashimoto, Masayoshi K. Hiraiwa, Francisco Sanchez-Bayo, Taku Kadoya, Daisuke Hayasaka
Summary: Systemic insecticides and rising temperatures have combined effects on the abundance of Odonata nymphs in paddy fields. The standalone effect of insecticide exposure decreased the Odonata community, while nymphs decreased synergistically with temperature rise in paddy water. However, the impacts of each stressor alone varied among species.
ENVIRONMENTAL POLLUTION
(2024)
Article
Environmental Sciences
Marco Vecchiato, Carlo Barbante, Elena Barbaro, Francois Burgay, Warren R. L. Cairns, Alice Callegaro, David Cappelletti, Federico Dallo, Marianna D'Amico, Matteo Feltracco, Jean-Charles Gallet, Andrea Gambaro, Catherine Larose, Niccolo Maffezzoli, Mauro Mazzola, Ivan Sartorato, Federico Scoto, Clara Turetta, Massimiliano Varde, Zhiyong Xie, Andrea Spolaor
Summary: The Arctic region is facing contamination from long-range pollution and local human activities. Polycyclic Aromatic Hydrocarbons (PAHs) are used as environmental indicators for emission, transport, and deposition processes. Research conducted in the Arctic surface snow in Ny-Ålesund, Svalbard from October 2018 to May 2019 shows that long-range inputs of PAHs mainly occur in winter, while the most abundant analyte retene exhibits opposite seasonal trends.
ENVIRONMENTAL POLLUTION
(2024)
Review
Environmental Sciences
Maoshui Zhuo, Zhijie Chen, Xiaoqing Liu, Wei Wei, Yansong Shen, Bing-Jie Ni
Summary: This paper discusses the application of three catalytic processes (photocatalysis, electrocatalysis, and biocatalysis) in the management of microplastic pollution, and introduces the efficiency and catalytic mechanisms of different catalysts. It also proposes the development prospects for sustainable management of microplastic pollution.
ENVIRONMENTAL POLLUTION
(2024)
Article
Environmental Sciences
Shiyu Chen, Zhenzhen Shi, Qiang Zhang
Summary: In this study, a human physiologically based pharmacokinetic (PBPK) model of diethyl phthalate (DEP) was developed to assess its toxicity. The model considers the distribution and metabolism of DEP and its active metabolite monoethyl phthalate (MEP) in different tissue compartments. Sensitivity analysis and Bayesian Markov chain Monte Carlo (MCMC) simulations were performed to evaluate the uncertainty and variability of the model parameters. The results suggest that dermal absorption is an important route of exposure to DEP in the environment.
ENVIRONMENTAL POLLUTION
(2024)
Article
Environmental Sciences
Bangguo Wang, Lijing Wang, Wenxi Cen, Tao Lyu, Peter Jarvis, Yang Zhang, Yuanxun Zhang, Yinghui Han, Lei Wang, Gang Pan, Kaili Zhang, Wei Fan
Summary: This study investigates the feasibility and mechanisms of a chemical-free nanobubble-based AOP for treating organic micropollutants in water. The results show that the oxygen nanobubble AOP has a significantly higher removal efficiency compared to air and nitrogen nanobubbles. The treatment performance is not affected by pH and the presence of ions. Higher initial concentrations of the micropollutant lead to slower treatment processes, but similar removal performance is achieved in the end. The presence of organic matter reduces the removal rate of the micropollutant. The results have practical feasibility for water and wastewater treatment.
ENVIRONMENTAL POLLUTION
(2024)
Article
Environmental Sciences
Yingmei Huang, Jicai Yi, Yao Huang, Songxiong Zhong, Bin Zhao, Jing Zhou, Yuxuan Wang, Yiwen Zhu, Yanhong Du, Fangbai Li
Summary: This study investigates the impact of biochar on methylmercury (MeHg) accumulation in rice. The results show that biochar reduces MeHg levels in paddy soils by decreasing bioavailable Hg and microbial Hg methylation. Additionally, biochar decreases the uptake and translocation of MeHg in rice plants, resulting in a reduction of MeHg accumulation in rice grains.
ENVIRONMENTAL POLLUTION
(2024)
Article
Environmental Sciences
Nengde Zeng, Fei Huang, Jiani Du, Chenghao Huang, Qian Yang, Xinhua Zhan, Baoshan Xing
Summary: This study investigates the protein targets and protein-ligand interactions related to PAH contamination in crop xylem sap using computational tools. The results show that phenanthrene has a more pronounced effect on the xylem sap proteins of maize and wheat, with maize DEPs associated with lipid biosynthesis and wheat DEPs exhibiting an increase in ABC transporters. This study provides insights into the regulation and movement of PAHs within plant xylem.
ENVIRONMENTAL POLLUTION
(2024)
Article
Environmental Sciences
Xinwei Chen, Hao Ma, Run Wang, Man Wang, Binbin Zhu, Yanqing Cong, Xiayue Zhu, Guoqin Wang, Yi Zhang
Summary: Co3O4/TiO2-NRs electrodes with excellent photoresponse were prepared via plasma-assisted modification of Co3O4 on TiO2. The combination of Co3O4 and TiO2 improved the light utilization efficiency and showed potential for degradation of pollutants.
ENVIRONMENTAL POLLUTION
(2024)
Article
Environmental Sciences
Wenjing Ji, Liying Song, Jing Wang, Hongqing Song
Summary: This study conducted a life-cycle assessment to examine the correlation between natural gas consumption and carbon emissions in different end uses in China. The results showed that both natural gas consumption and life-cycle carbon emissions have been increasing since 2017. Significant variations in NG life-cycle carbon emissions were found across different provinces and sectors, highlighting the need for targeted efforts to reduce carbon emissions.
ENVIRONMENTAL POLLUTION
(2024)
Article
Environmental Sciences
Youyi Chen, Boxuan Zhang, Pojun Zhang, Guogui Shi, Hao Liang, Wu Cai, Jingyu Gao, Sumin Zhuang, Kaiyin Luo, Jiaqi Zhu, Chaoxiang Chen, Kunyu Ma, Jinrong Chen, Chun Hu, Xueci Xing
Summary: The synergistic effects of trace sulfadiazine and cast-iron corrosion scales on the formation of disinfection by-products in drinking water distribution systems were investigated. The presence of magnetite resulted in increased concentrations of DBPs due to the higher microbial activity and enhanced microbial extracellular electron transport pathway. The study highlights the importance of considering trace antibiotics pollution and corrosion scales in water sources for DBP control.
ENVIRONMENTAL POLLUTION
(2024)
Review
Environmental Sciences
Bishwa Raj Pokharel, Vijay Sheri, Manoj Kumar, Zhiyong Zhang, Baohong Zhang
Summary: This review summarizes the interactions, uptake, and transport of aluminum nanoparticles (Al-NPs) in plants, highlighting their negative effects on plant growth and development, as well as their potential to alter plant defense systems and gene expression.
ENVIRONMENTAL POLLUTION
(2024)
Article
Environmental Sciences
Yonglu Wang, Fengsong Zhang, Xiaoyong Liao, Xiao Yang, Guixiang Zhang, Liyun Zhang, Chaojun Wei, Pengge Shi, Jiongxin Wen, Xiaorong Ju, Can Xu, Yang Liu, Ying Lan
Summary: This study aims to explore the effects of thiencarbazone-methyl center dot isoxaflutole on soil microflora and the potential mitigation mechanisms to bacterial communities. It was found that increasing the application of thiencarbazone-methyl center dot isoxaflutole resulted in increased stress on soil bacterial community structure and diversity. Increasing soil pH was recognized as a key factor in improving the diversity and structure of soil microflora. Supplemental use of nitrapyrin or modified attapulgite can increase soil pH and improve bacterial diversity.
ENVIRONMENTAL POLLUTION
(2024)
