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Evolution of tolerance to PCBs and susceptibility to a bacterial pathogen (Vibrio harveyi) in Atlantic killifish (Fundulus heteroclitus) from New Bedford (MA, USA) harbor

期刊

ENVIRONMENTAL POLLUTION
卷 157, 期 3, 页码 857-864

出版社

ELSEVIER SCI LTD
DOI: 10.1016/j.envpol.2008.11.016

关键词

PCB tolerance; Genetic adaptation; Fitness costs; Infectious disease

资金

  1. S EPA ORD NHEERL Atlantic Ecology Division [AED-05-079]
  2. Rhode Island Agricultural Experiment Station
  3. University of Rhode Island Coastal Fellowship
  4. NCRR, NIH [P20 RR16457]

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A population of the non-migratory estuarine fish Fundulus heteroclitus (Atlantic killifish) resident to New Bedford (NB), Massachusetts, USA, an urban harbor highly contaminated with polychlorinated biphenyls (PCBs), demonstrates recently evolved tolerance to some aspects of PCB toxicity. PCB toxicology, ecological theory, and some precedence supported expectations of increased susceptibility to pathogens in NB killifish. However, laboratory bacterial challenges of the marine pathogen Vibrio harveyi to wild fish throughout the reproductive season and to their mature laboratory-raised progeny demonstrated comparable survival by NB and reference killifish, and improved survival by NB males. These results are inconsistent with hypothesized trade-offs of adaptation, and suggest that evolved tolerance in NB killifish may include mechanisms that minimize the immunosuppressive effects of PCBs. Compensatory strategies of populations persisting in highly contaminated environments provide a unique perspective for understanding the long-term ecological effects of toxic chemicals. Published by Elsevier Ltd.

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