Predicting Later-Life Outcomes of Early-Life Exposures

Pre-eclampsia and offspring cardiovascular health: mechanistic insights from experimental studies

(2012) Esther F. Davis et al.   CLINICAL SCIENCE

Breast cancer following diethylstilbestrol exposure in utero: insights from a tragedy

(2012) Hans-Olov Adami et al.   EUROPEAN JOURNAL OF EPIDEMIOLOGY

Metabolomics in newborns with intrauterine growth retardation (IUGR): urine reveals markers of metabolic syndrome

(2012) Angelica Dessì et al.   Journal of Maternal-Fetal & Neonatal Medicine

Genome-Wide Association Study Identifies Chromosome 10q24.32 Variants Associated with Arsenic Metabolism and Toxicity Phenotypes in Bangladesh

(2012) Brandon L. Pierce et al.   PLoS Genetics

Endocrine disrupting chemicals and the developmental programming of adipogenesis and obesity

(2011) Amanda Janesick et al.   BIRTH DEFECTS RESEARCH PART C-EMBRYO TODAY-REVIEWS

Evidence for widespread changes in promoter methylation profile in human placenta in response to increasing gestational age and environmental/stochastic factors

(2011) Boris Novakovic et al.   BMC GENOMICS

Determinants of Blood Pressure in Preschool Children

(2011) Giacomo D. Simonetti et al.   CIRCULATION

Epigenetic Gene Promoter Methylation at Birth Is Associated With Child's Later Adiposity

(2011) K. M. Godfrey et al.   DIABETES

Longitudinal study of smoking cessation before pregnancy and children's cognitive abilities at 56months of age

(2011) Kati Heinonen et al.   EARLY HUMAN DEVELOPMENT

Arsenic Toxicology: Translating between Experimental Models and Human Pathology

(2011) J. Christopher States et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Maternal cigarette smoking during pregnancy is associated with downregulation ofmiR-16,miR-21, andmiR-146ain the placenta

(2011) Matthew A. Maccani et al.   Epigenetics

Infant growth restriction is associated with distinct patterns of DNA methylation in human placentas

(2011) Carolyn E. Banister et al.   Epigenetics

Birthweight is associated with DNA promoter methylation of the glucocorticoid receptor in human placenta

(2011) Amanda C. Filiberto et al.   Epigenetics

Mother's body size and placental size predict coronary heart disease in men

(2011) J. G. Eriksson et al.   EUROPEAN HEART JOURNAL

Prenatal and postnatal tobacco smoke exposure and development of insulin resistance in 10 year old children

(2011) Elisabeth Thiering et al.   INTERNATIONAL JOURNAL OF HYGIENE AND ENVIRONMENTAL HEALTH

The Sp1 Transcription Factor Is Crucial for the Expression of 11β-Hydroxysteroid Dehydrogenase Type 2 in Human Placental Trophoblasts

(2011) J. N. Li et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Maternal Influenza Viral Infection Causes Schizophrenia-Like Alterations of 5-HT2A and mGlu2 Receptors in the Adult Offspring

(2011) J. L. Moreno et al.   JOURNAL OF NEUROSCIENCE

Intrauterine Growth Restriction as a Potential Risk Factor for Disease Onset in Adulthood

(2011) A.A. Varvarigou   JOURNAL OF PEDIATRIC ENDOCRINOLOGY & METABOLISM

Minireview: PPARγ as the target of obesogens

(2011) Amanda Janesick et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Endocrine disrupting chemicals and disease susceptibility

(2011) Thaddeus T. Schug et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

A proposed mechanism for autism: an aberrant neuroimmune response manifested as a psychiatric disorder

(2011) M.R. Buehler   MEDICAL HYPOTHESES

MicroRNAs in Development and Disease

(2011) Danish Sayed et al.   PHYSIOLOGICAL REVIEWS

Structural and Regulatory Characterization of the Placental Epigenome at Its Maternal Interface

(2011) Tianjiao Chu et al.   PLoS One

miR-16 and miR-21 Expression in the Placenta Is Associated with Fetal Growth

(2011) Matthew A. Maccani et al.   PLoS One

Developmental plasticity and developmental origins of non-communicable disease: Theoretical considerations and epigenetic mechanisms

(2011) Mark Hanson et al.   PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY

Maternal infection and immune involvement in autism

(2011) Paul H. Patterson   TRENDS IN MOLECULAR MEDICINE

Relationship between birth size and coronary heart disease in China

(2010) Zhongjie Fan et al.   ANNALS OF MEDICINE

Nutrition, Epigenetics, and Developmental Plasticity: Implications for Understanding Human Disease

(2010) Graham C. Burdge et al.   Annual Review of Nutrition

Maternal protein restriction with or without folic acid supplementation during pregnancy alters the hepatic transcriptome in adult male rats

(2010) Karen A. Lillycrop et al.   BRITISH JOURNAL OF NUTRITION

Perinatal, maternal, and fetal characteristics of children diagnosed with attention-deficit-hyperactivity disorder: results from a population-based study utilizing the Swedish Medical Birth Register

(2010) PEIK GUSTAFSSON et al.   DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY

Preterm Birth--A Risk Factor for Type 2 Diabetes?: The Helsinki Birth Cohort Study

(2010) E. Kajantie et al.   DIABETES CARE

Low birthweight and premature birth are both associated with type 2 diabetes in a random sample of middle-aged Danes

(2010) K. Pilgaard et al.   DIABETOLOGIA

Uteroplacental insufficiency increases visceral adiposity and visceral adipose PPARγ2 expression in male rat offspring prior to the onset of obesity

(2010) Lisa A. Joss-Moore et al.   EARLY HUMAN DEVELOPMENT

An Emerging Role for Epigenetic Dysregulation in Arsenic Toxicity and Carcinogenesis

(2010) Xuefeng Ren et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

The neuropathological contribution of prenatal inflammation to schizophrenia

(2010) Urs Meyer et al.   Expert Review of Neurotherapeutics

Lung function in adults following in utero and childhood exposure to arsenic in drinking water: preliminary findings

(2010) David C. Dauphiné et al.   INTERNATIONAL ARCHIVES OF OCCUPATIONAL AND ENVIRONMENTAL HEALTH

Prevalence of Extreme Obesity in a Multiethnic Cohort of Children and Adolescents

(2010) Corinna Koebnick et al.   JOURNAL OF PEDIATRICS

Infant Obesity: Are We Ready to Make this Diagnosis?

(2010) David P. McCormick et al.   JOURNAL OF PEDIATRICS

Unusual Cancer Excess After Neonatal Arsenic Exposure From Contaminated Milk Powder

(2010) T. Yorifuji et al.   JNCI-Journal of the National Cancer Institute

Prenatal Exposure to the Environmental Obesogen Tributyltin Predisposes Multipotent Stem Cells to Become Adipocytes

(2010) Séverine Kirchner et al.   MOLECULAR ENDOCRINOLOGY

Review: Reactive oxygen and nitrogen species and functional adaptation of the placenta

(2010) L. Myatt   PLACENTA

Cytosine Methylation Dysregulation in Neonates Following Intrauterine Growth Restriction

(2010) Francine Einstein et al.   PLoS One

Maternal Infection and Schizophrenia: Implications for Prevention

(2010) A. S. Brown et al.   SCHIZOPHRENIA BULLETIN

Neonatal Behavioral Changes in Rats With Gestational Exposure to Lipopolysaccharide: A Prenatal Infection Model for Developmental Neuropsychiatric Disorders

(2010) M. Baharnoori et al.   SCHIZOPHRENIA BULLETIN

Arsenic, Stem Cells, and the Developmental Basis of Adult Cancer

(2010) E. J. Tokar et al.   TOXICOLOGICAL SCIENCES

Long-Term Consequences of Fetal and Neonatal Nicotine Exposure: A Critical Review

(2010) Jennifer E. Bruin et al.   TOXICOLOGICAL SCIENCES

REVIEW ARTICLE: Epigenetics in the Placenta

(2009) Matthew A. Maccani et al.   AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY

The developmental origins of adult disease

(2009) Lisa A Joss-Moore et al.   CURRENT OPINION IN PEDIATRICS

Epigenetics: intrauterine growth retardation (IUGR) modifies the histone code along the rat hepatic IGF-1 gene

(2009) Qi Fu et al.   FASEB JOURNAL

Testing the Fetal Origins Hypothesis in a developing country: evidence from the 1918 Influenza Pandemic

(2009) Richard E. Nelson   HEALTH ECONOMICS

DNA methylation and gene expression differences in children conceived in vitro or in vivo

(2009) Sunita Katari et al.   HUMAN MOLECULAR GENETICS

DNA methylation differences after exposure to prenatal famine are common and timing- and sex-specific

(2009) Elmar W. Tobi et al.   HUMAN MOLECULAR GENETICS

Epigenetics and fetal adaptation to perinatal events: Diversity through fidelity1

(2009) L. A. Joss-Moore et al.   JOURNAL OF ANIMAL SCIENCE

Hypothalamic proopiomelanocortin promoter methylation becomes altered by early overfeeding: an epigenetic model of obesity and the metabolic syndrome

(2009) Andreas Plagemann et al.   JOURNAL OF PHYSIOLOGY-LONDON

Environmental estrogens and obesity

(2009) Retha R. Newbold et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Phenotypic dichotomy following developmental exposure to perfluorooctanoic acid (PFOA) in female CD-1 mice: Low doses induce elevated serum leptin and insulin, and overweight in mid-life☆

(2009) Erin P. Hines et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Abnormal methylation at the KvDMR1 imprinting control region in clinically normal children conceived by assisted reproductive technologies

(2009) M.V. Gomes et al.   MOLECULAR HUMAN REPRODUCTION

Wnt and PPARγ signaling in osteoblastogenesis and adipogenesis

(2009) Ichiro Takada et al.   Nature Reviews Rheumatology

Weight Status in the First 6 Months of Life and Obesity at 3 Years of Age

(2009) E. M. Taveras et al.   PEDIATRICS

Relation of DNA Methylation of 5′-CpG Island of ACSL3 to Transplacental Exposure to Airborne Polycyclic Aromatic Hydrocarbons and Childhood Asthma

(2009) Frederica Perera et al.   PLoS One

Periconceptional Maternal Folic Acid Use of 400 µg per Day Is Related to Increased Methylation of the IGF2 Gene in the Very Young Child

(2009) Régine P. Steegers-Theunissen et al.   PLoS One

Characterization of the Hypothalamic-Pituitary-Adrenal Axis Response to Atrazine and Metabolites in the Female Rat

(2009) Melanie J. P. Fraites et al.   TOXICOLOGICAL SCIENCES

Arsenic exacerbates atherosclerotic lesion formation and inflammation in ApoE-/- mice

(2009) Sanjay Srivastava et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Fat and Beyond: The Diverse Biology of PPARγ

(2008) Peter Tontonoz et al.   Annual Review of Biochemistry

Transgenerational effects of prenatal exposure to the Dutch famine on neonatal adiposity and health in later life

(2008) RC Painter et al.   BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY

Transmission of raised blood pressure and endothelial dysfunction to the F2 generation induced by maternal protein restriction in the F0, in the absence of dietary challenge in the F1 generation

(2008) Christopher Torrens et al.   BRITISH JOURNAL OF NUTRITION

Feeding pregnant rats a protein-restricted diet persistently alters the methylation of specific cytosines in the hepatic PPARα promoter of the offspring

(2008) Karen A. Lillycrop et al.   BRITISH JOURNAL OF NUTRITION

Exposure of Neonatal Rats to Parathion Elicits Sex-Selective Reprogramming of Metabolism and Alters the Response to a High-Fat Diet in Adulthood

(2008) T. Leon Lassiter et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Folate Deficiency, Hyperhomocysteinemia, Low Urinary Creatinine, and Hypomethylation of Leukocyte DNA Are Risk Factors for Arsenic-Induced Skin Lesions

(2008) J. Richard Pilsner et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Use of Anthropometric Indices to Reveal Nutritional Status: Normative Data from 10,226 Chinese Neonates

(2008) Tai-Fai Fok et al.   Neonatology

Persistent epigenetic differences associated with prenatal exposure to famine in humans

(2008) B. T. Heijmans et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Adult brain and behavioral pathological markers of prenatal immune challenge during early/middle and late fetal development in mice

(2007) Urs Meyer et al.   BRAIN BEHAVIOR AND IMMUNITY