☆ 4.7 Letter

Calculation of Mercury's Effects on Neurodevelopment

ENVIRONMENTAL HEALTH PERSPECTIVES (2012)

期刊

ENVIRONMENTAL HEALTH PERSPECTIVES

卷 120, 期 12, 页码 A452-A452

出版社

US DEPT HEALTH HUMAN SCIENCES PUBLIC HEALTH SCIENCE

DOI: 10.1289/ehp.1206033

关键词

-

类别

Environmental Sciences Public, Environmental & Occupational Health Toxicology

向作者/读者索取更多资源

Protocol

Reagent

作者

我是这篇论文的作者

点击您的名字以认领此论文并将其添加到您的个人资料中。

评论

主要评分

4.7

评分不足

次要评分

新颖性

-

重要性

-

科学严谨性

-

评价这篇论文

推荐

Article Biochemistry & Molecular Biology

The Effects of Bilirubin and Lumirubin on the Differentiation of Human Pluripotent Cell-Derived Neural Stem Cells

Nikola Capkova, Veronika Pospisilova, Veronika Fedorova, Jan Raska, Katerina Pospisilova, Matteo Dal Ben, Ales Dvorak, Jitka Viktorova, Dasa Bohaciakova, Libor Vitek

Summary: The study compared the effects of bilirubin and its major photo-oxidation product on neural stem cells, showing that bilirubin exerted dose-dependent cytotoxicity while the photo-oxidation product had a substantial impact on cell morphology and protein redistribution.

ANTIOXIDANTS (2021)

添加到收藏夹

Article Environmental Sciences

The adverse effects of fluxapyroxad on the neurodevelopment of zebrafish embryos

Huilin Yu, Junhui Zhang, Yinghong Chen, Juan Chen, Yang Qiu, Yan Zhao, Honghao Li, Shengyao Xia, Shiguo Chen, Jiajin Zhu

Summary: This study investigated the neurotoxic effects of Fluxapyroxad on zebrafish embryos, revealing malformations, motor aberrations, and disrupted neurodevelopment. It also provided evidence of Fluxapyroxad's detrimental impact on the zebrafish nervous system.

CHEMOSPHERE (2022)

添加到收藏夹

Article Geosciences, Multidisciplinary

Sulfides in Mercury's Mantle: Implications for Mercury's Interior as Interpreted From Moment of Inertia

L. H. Lark, S. Parman, C. Huber, E. M. Parmentier, J. W. Head

Summary: The partitioning of sulfur between Mercury's core and mantle provides insights into its formation conditions and early evolution. The presence of large quantities of sulfur-rich minerals in the mantle suggests reducing conditions during equilibration, while a depleted or oxidizing mantle is indicated by a higher moment of inertia.

GEOPHYSICAL RESEARCH LETTERS (2022)

添加到收藏夹

Article Oncology

Metformin effects on brain development following cranial irradiation in a mouse model

Nili Yuen, Kamila U. Szulc-Lerch, Yu-Qing Li, Cindi M. Morshead, Donald J. Mabbott, C. Shun Wong, Brian J. Nieman

Summary: The study suggests that metformin treatment has the potential to improve neuroanatomical outcomes after cranial radiation therapy, but the timing of treatment and the sex of the subjects can affect the results and caution is needed when considering repurposing metformin in clinical studies.

NEURO-ONCOLOGY (2021)

添加到收藏夹

Article Environmental Sciences

Effects of soil lead exposure and land use characteristics on neurodevelopment among children under 3 years of age in

Chi-Sian Kao, Ying-Lin Wang, Ting-Wu Chuang, Chuen-Bin Jiang, Hsing-Cheng Hsi, Kai-Wei Liao, Ling-Chu Chien

Summary: Lead exposure is associated with neurodevelopmental disorders in children. A study in northern Taiwan found that soil lead pollution and land use characteristics were linked to children's lead exposure, which in turn could impact their neurodevelopment. Hair and fingernail lead concentrations were negatively associated with expressive language scores, while soil lead exposure was positively associated with hair lead concentrations. Land use types around children's homes in northern Taiwan were associated with their neurodevelopmental abilities.

ENVIRONMENTAL POLLUTION (2021)

添加到收藏夹

Review Biochemistry & Molecular Biology

Effects of Cannabinoid Exposure during Neurodevelopment on Future Effects of Drugs of Abuse: A Preclinical Perspective

Aaron Mark Farrelly, Styliani Vlachou

Summary: The endocannabinoid system has a significant impact on neurodevelopment during embryonic, postnatal, and adolescent stages. Exposure to cannabinoids during the perinatal and adolescent periods can lead to multifaceted behavioral and molecular changes in rodents. Research focusing on sex-specific effects and clinically relevant cannabinoid treatments is needed to fill gaps in the current body of knowledge.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)

添加到收藏夹

Article Environmental Sciences

Effects of prenatal exposure to persistent organic pollutants on neonatal Outcomes:A mother-child cohort (Shanghai, China)

Su-Su Wang, An-Xin Lu, Lu-Lu Cao, Xiu-Fang Ran, Ya-Qian Wang, Chen Liu, Chong-Huai Yan

Summary: This study examined the impact of POPs exposure on birth outcomes. Findings showed adverse effects of prenatal exposure to HCB, β-HCH and p,p'-DDE on birth head circumference, particularly in girls. Further research is needed to explore gender differences and the effects of POPs on offspring growth and development.

ENVIRONMENTAL RESEARCH (2022)

添加到收藏夹

Article Environmental Sciences

Effects of low-dose methylcyclopentadienyl manganese tricarbonyl- derived manganese on the development of diencephalic dopaminergic neurons in zebrafish

Giulia Fasano, Rafael Soares Godoy, Elisa Angiulli, Ada Consalvo, Cristina Franco, Maria Mancini, Daniela Santucci, Enrico Alleva, Domenico Ciavardelli, Mattia Toni, Elio Biffali, Marc Ekker, Lorella Maria Teresa Canzoniero, Paolo Sordino

Summary: This study found that exposure to low levels of Mn derived from MMT leads to selective changes in DA neurons and long-term effects on exploratory behavior in adult fish. Although dopamine levels recover in adulthood, there are deficits in memory acquisition and consolidation.

ENVIRONMENTAL POLLUTION (2021)

添加到收藏夹

Review Behavioral Sciences

The intergenerational effects of parental physical activity on offspring brain and neurocognition in humans: A scoping review

Sarah R. Valkenborghs, Paige C. Dent, Chelsea M. Stillman

Summary: Animal models suggest that physical activity has intergenerational effects on brain health and neurocognition. This scoping review examines the human literature in this area and finds limited understanding of the intergenerational effects of parental physical activity on offspring brain and neurocognition, especially regarding paternal preconception physical activity. More experimental studies with longer offspring follow-up and more objective and mechanistic assessments are needed.

NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS (2022)

添加到收藏夹

Article Engineering, Multidisciplinary

Magnetic storms in Mercury's magnetosphere

QiuGang Zong, JiuTong Zhao, JianJun Liu, SuiYan Fu, WeiJie Sun, Hui Zhang, Guan Le, Robert Rankin, Yong Wei

Summary: This study presents evidence of geomagnetic storms in Mercury's magnetosphere based on observations made by the MESSENGER spacecraft. The results show that despite the significant differences in magnetic field strength, magnetosphere size, and process timescales compared to Earth, a bifurcated ring current can form in Mercury's magnetosphere and initiate magnetic storms under strong solar wind driving.

SCIENCE CHINA-TECHNOLOGICAL SCIENCES (2022)

添加到收藏夹

Review Pediatrics

The effects of early anesthesia on neurodevelopment: A systematic review

Julia Grabowski, Adam Goldin, L. Grier Arthur, Alana L. Beres, Yigit S. Guner, Yue-Yung Hu, Akemi L. Kawaguchi, Lorraine I. Kelley-Quon, Jarod P. McAteer, Doug Miniati, Elizabeth J. Renaud, Robert Ricca, Mark B. Slidell, Caitlin A. Smith, Juan E. Sola, Stig Somme, Cynthia D. Downard, Ankush Gosain, Patricia Valusek, Shawn D. St Peter, Narasimhan 'Sim' Jagannathan, Roshni Dasgupta

Summary: Based on a systematic review, single exposure to general anesthesia does not seem to have a significant effect on general neurodevelopment, but prolonged or multiple exposures may have adverse effects. Exposure to general anesthesia may affect the same domains of development at different ages, but regional anesthetic techniques can mitigate the risks of neurotoxicity.

JOURNAL OF PEDIATRIC SURGERY (2021)

添加到收藏夹

Article Environmental Sciences

Effects of prenatal exposure to pyrethroid pesticides on neurodevelopment of 1-year- old children: A birth cohort study in China

Zhiye Qi, Xiaoxiao Song, Xia Xiao, Kek Khee Loo, May C. Wang, Qinghua Xu, Jie Wu, Shuqi Chen, Ying Chen, Lingling Xu, Yan Li

Summary: This study found that pregnant women are commonly exposed to pyrethroid pesticides. The results indicate that prenatal exposure to pyrethroids may have deleterious effects on infant neurodevelopment, particularly at a high dosage of exposure.

ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY (2022)

添加到收藏夹

Review Nutrition & Dietetics

Potential Epigenetic Effects of Human Milk on Infants' Neurodevelopment

Giannoula Gialeli, Ourania Panagopoulou, Georgios Liosis, Tania Siahanidou

Summary: Breast milk feeding, especially in preterm babies, has many advantages, including reducing the risk of non-communicable diseases and improving neurodevelopmental outcomes. The bioactive components of breast milk, such as non-coding RNAs, stem cells, and microbiome, may play a role in this association through potential epigenetic effects.

NUTRIENTS (2023)

添加到收藏夹

Review Microbiology

Chronic Effects of Dietary Pesticides on the Gut Microbiome and Neurodevelopment

Jessica Gama, Bianca Neves, Antonio Pereira

Summary: Agricultural pesticides, including extremely toxic substances, continue to be used in developing countries like Brazil, posing a potential hazard to human health. Recent studies have shown that chronic dietary exposure to low levels of pesticides can impact the human gut microbiota. However, government regulatory agencies have not specifically recognized the possible harmful effects of pesticides on human health.

FRONTIERS IN MICROBIOLOGY (2022)

添加到收藏夹

Article Environmental Sciences

Integrated measures of lead and manganese exposure improve estimation of their joint effects on cognition in Italian school-age children

Yuri Levin-Schwartz, Birgit Claus Henn, Chris Gennings, Brent A. Coull, Donatella Placidi, Megan K. Horton, Donald R. Smith, Roberto G. Lucchini, Robert O. Wright

Summary: Through the study, it was found that joint exposure to Pb and Mn can have adverse effects on children's IQ, while individual exposure to each metal does not significantly impact IQ. Combining exposure data from different media can provide a more accurate estimation of the health effects of mixture exposure.

ENVIRONMENT INTERNATIONAL (2021)

添加到收藏夹

Article Statistics & Probability

Controlling the familywise error rate when performing multiple comparisons in a linear latent variable model

Brice Ozenne, Esben Budtz-Jorgensen, Sebastian Elgaard Ebert

Summary: This article introduces the use of the max-test procedure in latent variable models for multiple testing. The effectiveness of the procedure for Wald and Score tests in LVMs is evaluated through simulation studies. The procedure is then applied to quantify the neuroinflammatory response to mild traumatic brain injury in multiple brain regions.

COMPUTATIONAL STATISTICS (2023)

添加到收藏夹

Correction Environmental Sciences

Bone mass density following developmental exposures to perfluoroalkyl substances (PFAS): a longitudinal cohort study (VOL 22, PG 15, YEAR 2023)

Annelise Blomberg, Jann Mortensen, Pal Weihe, Philippe Grandjean

ENVIRONMENTAL HEALTH (2023)

添加到收藏夹

Article Clinical Neurology

Directionality of the Association Between Epilepsy and Depression A Nationwide Register-Based Cohort Study

Eva Bolling-Ladegaard, Julie Werenberg Dreier, Lars Vedel Kessing, Esben Budtz-Jorgensen, Kasper Lolk, Jakob Christensen

Summary: This study investigates the magnitude and long-term association between epilepsy and depression, comparing with the risks of the 2 disorders after another chronic medical illness (asthma). Results show a long-term bidirectional relationship between depression and epilepsy, with higher risk estimates than for epilepsy or depression after asthma.

NEUROLOGY (2023)

添加到收藏夹

Article Public, Environmental & Occupational Health

Association Between Prenatal and Early Postnatal Exposure to Perfluoroalkyl Substances and IQ Score in 7-Year-Old Children From the Odense Child Cohort

Iben Have Beck, Niels Bilenberg, Soeren Moeller, Flemming Nielsen, Philippe Grandjean, Frederik Damsgaard Hojsager, Thorhallur Ingi Halldorsson, Christel Nielsen, Tina Kold Jensen

Summary: The study found that prenatal and early postnatal exposure to perfluoroalkyl substances (PFAS) may affect intelligence quotient (IQ), especially higher concentrations of perfluorooctane sulfonic acid (PFOS) and perfluorooctanoic acid (PFOA) were associated with lower IQ scores.

AMERICAN JOURNAL OF EPIDEMIOLOGY (2023)

添加到收藏夹

Review Environmental Sciences

Consideration of pathways for immunotoxicity of per- and polyfluoroalkyl substances (PFAS)

Veronika Ehrlich, Wieneke Bil, Rob Vandebriel, Berit Granum, Mirjam Luijten, Birgitte Lindeman, Philippe Grandjean, Andreas-Marius Kaiser, Ingrid Hauzenberger, Christina Hartmann, Claudia Gundacker, Maria Uhl

Summary: PFAS are a public health concern due to their persistent occurrence and adverse effects on the immune system. The mechanisms underlying the impact on the immune system are not fully understood. Various PFAS affect multiple aspects of the immune system, with the developing immune system being particularly vulnerable to toxic insults.

ENVIRONMENTAL HEALTH (2023)

添加到收藏夹

Article Environmental Sciences

Benchmark dose calculations for PFAS exposure based on two data sets on immunotoxic effects

Esben Budtz-Jorgensen, Philippe Grandjean

Summary: By analyzing two data sets using the BMD method, the study found that using different dose-response models can lead to more accurate results. The toxicity of different PFAS was compared, confirming differences in toxicity among them. It was concluded that EFSA's proposed tolerable exposure limit is too high, while the EPA's proposal is more in line with the research results.

ENVIRONMENTAL HEALTH (2023)

添加到收藏夹

Article Environmental Sciences

Early-Life Exposure to Ambient Air Pollution from Multiple Sources and Asthma Incidence in Children: A Nationwide Birth Cohort Study from Denmark

Marie Pedersen, Shuo Liu, Jiawei Zhang, Zorana Jovanovic Andersen, Jorgen Brandt, Esben Budtz-Jorgensen, Klaus Bonnelykke, Lise Marie Frohn, Anne-Marie Nybo Andersen, Matthias Ketzel, Jibran Khan, Leslie Stayner, Bert Brunekreef, Steffen Loft

Summary: This study found that early-life exposure to ambient air pollution increases the risk of childhood asthma.

ENVIRONMENTAL HEALTH PERSPECTIVES (2023)

添加到收藏夹

Article Endocrinology & Metabolism

Weight loss relapse associated with exposure to perfluoroalkylate substances

Philippe Grandjean, Alessandra Meddis, Flemming Nielsen, Anders Sjodin, Mads F. F. Hjorth, Arne Astrup, Esben Budtz-Jorgensen

Summary: The objective of this study was to test the association between perfluorinated alkylate substance (PFAS) exposures and body weight increases in a dietary intervention study. The results showed that elevated plasma concentrations of PFOA and PFHxS were significantly associated with increased weight gain, exceeding the effects of different diet groups. The findings suggest that obesogenic PFASs may contribute to the obesity pandemic.

OBESITY (2023)

添加到收藏夹

Article Environmental Sciences

Prenatal and early postnatal exposure to perfluoroalkyl substances and bone mineral content and density in the Odense Child Cohort

Frederik Damsgaard Hojsager, Annika Sigvaldsen, Marianne Skovsager Andersen, Anders Juul, Flemming Nielsen, Soren Moller, Henrik Boye Thybo Christesen, Anders Grontved, Philippe Grandjean, Tina Kold Jensen

Summary: This study found that prenatal and early postnatal exposure to perfluoroalkyl substances (PFAS) is associated with lower bone mineral density (BMD) at age 7. The association is stronger for exposure at 18 months than prenatal exposure.

ENVIRONMENT INTERNATIONAL (2023)

添加到收藏夹

Article Environmental Sciences

Predictors of serum- per- and polyfluoroalkyl substance (PFAS) concentrations among infants in Guinea-Bissau, West Africa

Marzanna Marianna Sorensen, Ane Baerent Fisker, Christine Dalgard, Kristoffer Jarlov Jensen, Flemming Nielsen, Christine Stabell Benn, Philippe Grandjean, Amalie Timmermann

Summary: The aim of this study was to identify predictors of infant serum-PFAS concentrations. The study found that the location of residence was the most important determinant of serum-PFAS concentrations among Guinea-Bissau infants, indicating a potential role of diet as affected by the global spread of PFAS, but further research is needed to explore reasons for the regional differences in PFAS exposure.

ENVIRONMENTAL RESEARCH (2023)

添加到收藏夹

Article Engineering, Environmental

Paired Liver:Plasma PFAS Concentration Ratios from Adolescents in the Teen-LABS Study and Derivation of Empirical and Mass Balance Models to Predict and Explain Liver PFAS Accumulation

Brittney O. Baumert, Fabian C. Fischer, Flemming Nielsen, Philippe Grandjean, Scott Bartell, Nikos Stratakis, Douglas I. Walker, Damaskini Valvi, Rohit Kohli, Thomas Inge, Justin Ryder, Todd Jenkins, Stephanie Sisley, Stavra Xanthakos, Sarah Rock, Michele A. La Merrill, David Conti, Rob Mcconnell, Lida Chatzi

Summary: Animal studies have suggested that the liver is a major site for the accumulation and toxicity of per- and polyfluoroalkyl substances (PFAS), but these findings have not been replicated in human populations. In this study, concentrations of seven PFAS were measured in matched liver and plasma samples from 64 adolescents undergoing bariatric surgery. A multilinear regression model based on toxicokinetic descriptors perfectly explained the liver:plasma concentration ratios. Among the PFAS congeners examined, perfluoroheptanoic acid (PFHpA) had a considerably higher liver:plasma concentration ratio. Mechanistic modeling suggested that complex kinetic transport processes contribute to the high liver:plasma concentration ratio of PFHpA. This study demonstrates the potential of combining biomonitoring data with mechanistic modeling to understand the internal distribution and specific target organ toxicity of PFAS in humans.

ENVIRONMENTAL SCIENCE & TECHNOLOGY (2023)

添加到收藏夹

Article Public, Environmental & Occupational Health

Dose dependence of prenatal fluoride exposure associations with cognitive performance at school age in three prospective studies

Philippe Grandjean, Alessandra Meddis, Flemming Nielsen, Iben H. Beck, Niels Bilenberg, Carly Goodman, Howard Hu, Christine Till, Esben Budtz-Jorgensen

Summary: By merging data from three birth cohort studies, the study found a statistically significant association between urine-fluoride concentrations and IQ, suggesting the need for protection against fluoride toxicity in pregnant women and children.

EUROPEAN JOURNAL OF PUBLIC HEALTH (2023)

添加到收藏夹

Article Oncology

COVID-19 Infection despite Previous Vaccination in Cancer Patients and Healthcare Workers: Results from a French Prospective Multicenter Cohort (PAPESCO-19)

Valerie Seegers, Guillaume Rousseau, Ke Zhou, Audrey Blanc-Lapierre, Frederic Bigot, Hakim Mahammedi, Aurelien Lambert, Camille Moreau-Bachelard, Mario Campone, Thierry Conroy, Frederique Penault-Llorca, Martine M. Bellanger, Jean-Luc Raoul

Summary: In two cohorts of vaccinated cancer patients and healthcare workers, 5% experienced a breakthrough COVID-19 infection. These infections were more common among younger cancer patients with certain types of cancers and those receiving chemotherapy or targeted therapy. The infections occurred either shortly after vaccination or several months after completing the vaccination course. However, the COVID-19 cases in vaccinated individuals were not severe.

CANCERS (2023)

添加到收藏夹

Article Radiology, Nuclear Medicine & Medical Imaging

Evaluation of thin-slice abdominal DECT using deep-learning image reconstruction in 74 keV virtual monoenergetic images: an image quality comparison

Jack J. J. Xu, Lars Loenn, Esben Budtz-Jorgensen, Samir Jawad, Peter S. S. Ulriksen, Kristoffer L. L. Hansen

Summary: This study compared the noise, contrast-to-noise ratio (CNR), signal-to-noise ratio (SNR), and image quality of deep-learning image reconstruction (DLIR) vs. adaptive statistical iterative reconstruction (ASIR-V) in gray scale 74 keV virtual monoenergetic (VM) abdominal dual-energy CT (DECT) with different slice thicknesses. The results showed that DLIR significantly reduced image noise, increased CNR and SNR, and improved image quality, especially in 0.625 mm slice images, compared to ASIR-V.

ABDOMINAL RADIOLOGY (2023)

添加到收藏夹

暂无数据

© Peeref 2019-2024. All rights reserved.