Evaluation of Developmental Toxicants and Signaling Pathways in a Functional Test Based on the Migration of Human Neural Crest Cells

Can case study approaches speed implementation of the NRC report: “Toxicity Testing in the 21st Century: A Vision and a Strategy?”

(2014) Melvin Andersen   ALTEX-Alternatives to Animal Experimentation

Developmental exposure to valproate and ethanol alters locomotor activity and retino-tectal projection area in zebrafish embryos

(2012) John Cowden et al.   REPRODUCTIVE TOXICOLOGY

The stem cells of the neural crest

(2011) Nicole M. Le Douarin et al.   CELL CYCLE

Effects of Cryopreservation on the Transcriptome of Human Embryonic Stem Cells After Thawing and Culturing

(2011) Vilas Wagh et al.   Stem Cell Reviews and Reports

Sensitivity of Dopaminergic Neuron Differentiation from Stem Cells to Chronic Low-Dose Methylmercury Exposure

(2011) Bastian Zimmer et al.   TOXICOLOGICAL SCIENCES

Assessment of Chemical-Induced Impairment of Human Neurite Outgrowth by Multiparametric Live Cell Imaging in High-Density Cultures

(2011) Nina V. Stiegler et al.   TOXICOLOGICAL SCIENCES

Integration of Dosimetry, Exposure, and High-Throughput Screening Data in Chemical Toxicity Assessment

(2011) Barbara A. Wetmore et al.   TOXICOLOGICAL SCIENCES

Craniofacial birth defects: The role of neural crest cells in the etiology and pathogenesis of Treacher Collins syndrome and the potential for prevention

(2010) Paul A. Trainor   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

Coordinated waves of gene expression during neuronal differentiation of embryonic stem cells as basis for novel approaches to developmental neurotoxicity testing

(2010) B Zimmer et al.   CELL DEATH AND DIFFERENTIATION

Derivation of neural crest cells from human pluripotent stem cells

(2010) Gabsang Lee et al.   Nature Protocols

The Mood Stabilizers Valproic Acid and Lithium Enhance Mesenchymal Stem Cell Migration via Distinct Mechanisms

(2010) Li-Kai Tsai et al.   NEUROPSYCHOPHARMACOLOGY

The use of developmental neurotoxicity data in pesticide risk assessments

(2010) Kathleen C. Raffaele et al.   NEUROTOXICOLOGY AND TERATOLOGY

Collective Cell Migration

(2009) Pernille Rørth   Annual Review of Cell and Developmental Biology

Human Neurospheres as Three-Dimensional Cellular Systems for Developmental Neurotoxicity Testing

(2009) Michaela Moors et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Plasticity of cell migration: a multiscale tuning model

(2009) Peter Friedl et al.   JOURNAL OF CELL BIOLOGY

Modelling pathogenesis and treatment of familial dysautonomia using patient-specific iPSCs

(2009) Gabsang Lee et al.   NATURE

Chemical regulators have overreached

(2009) Thomas Hartung et al.   NATURE

Highly efficient neural conversion of human ES and iPS cells by dual inhibition of SMAD signaling

(2009) Stuart M Chambers et al.   NATURE BIOTECHNOLOGY

A Retrospective Performance Assessment of the Developmental Neurotoxicity Study in Support of OECD Test Guideline 426

(2008) Susan L. Makris et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

PCB126 Exposure Disrupts ZebraFish Ventricular and Branchial but Not Early Neural Crest Development

(2008) Adrian C. Grimes et al.   TOXICOLOGICAL SCIENCES