Article
Environmental Sciences
Chi-fong Ko, Yi-Chen Yang, Jennifer Ia Wen Wen Liu, Yang-hsin Shih
Summary: This study focused on the thermal treatment of PBDE-contaminated soil, with the optimal conditions determined to be heating at 450 degrees Celsius for 30 minutes with a heating rate of 10 degrees Celsius per minute. Through this method, BDE-209 was successfully removed from the soil to below detection limits, indicating the feasibility of remediating PBDE-contaminated soil through thermal treatment.
Article
Engineering, Chemical
Kaibo Huang, Haozhong Lin, Xueqin Tao, Mengyao Zou, Guining Lu
Summary: This study investigated the photodegradation of BDE-209 in soil suspensions. The results showed that BDE-209 can degrade in soil suspensions with a pseudo-first-order kinetics. UV light was found to be the main reason for BDE-209 degradation. Soil particle inhibited BDE-209 photodegradation due to the light-shielding effect. The presence of higher pH value and humic acid increased the degradation rate of BDE-209.
Article
Environmental Sciences
Qiqing Chen, Xiyang Zhang, Qiang Xie, Young Hwan Lee, Jae-Seong Lee, Huahong Shi
Summary: The presence of microplastics in natural aquatic environments can accelerate the degradation of organic pollutants and impact the endocrine system and thyroid function in aquatic organisms.
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
(2021)
Article
Agriculture, Dairy & Animal Science
Zehui Liu, Hulong Lei, Renyong Tang, Junhua Yang, Xiulan Guo, Renmao Huang, Qinxiong Rao, Lin Cheng, Zhihui Zhao
Summary: This study found that exposure to different doses of BDE-209 had significant impacts on the growth, blood parameters, carcass traits, and antioxidant capacity in broilers, indicating its toxic effects.
Article
Environmental Sciences
Jennifer Ia Wen Wen Liu, Yu-Jie Lin, Chi-Fong Ko, Jiann-yuan Ding, Yang-hsin Shih
Summary: A farm in Taoyuan, Taiwan has been contaminated with decabrominated diphenyl ether (BDE-209) for over 10 years, posing a hazardous risk to humans. The study investigates thermal treatment as a method to remove BDE-209 from soil. While heating to 450 degrees C for 30 minutes effectively removes BDE-209, it also reduces soil organic matter, damages microbial biomass, and affects revegetation. By using sugarcane bagasse as an amendment, soil fertility can be restored and bacterial composition improved, making it a promising method for sustainable remediation.
Article
Agricultural Engineering
Sonam Paliya, Ashootosh Mandpe, M. Suresh Kumar, Sunil Kumar
Summary: In this study, a novel bacterium capable of aerobically degrading BDE-209 was isolated from a municipal waste dumping site and identified as Bacillus tequilensis strain BDE-S1. The degradation of BDE-209 by BDE-S1 was found to be significantly correlated with bromide concentration, COD, TOC, and cell biomass, and the study suggested possible degradation pathways based on metabolite analysis. This research demonstrates the potential for using indigenously isolated Bacillus tequilensis strain BDE-S1 in the bioremediation of PBDEs from contaminated environments.
BIORESOURCE TECHNOLOGY
(2021)
Article
Fisheries
Xueyu Li, Haoran Zhang, Senqiu Qiao, Wenxue Ma, Jingzeng Cai, Xintong Zhang, Ziwei Zhang
Summary: This study developed fish kidney cell models of PBDE-47 poisoning and/or MEL treatment and found that PBDE-47 exposure resulted in increased cytoplasmic Ca2+ concentration, decreased miR-140-5p miRNA level, upregulation of TLR4 and NF-B, triggering of necroptosis and secretion of inflammatory factors. MEL could alleviate PBDE-47-induced toxicity through the regulation of calcium channels and restoration of the miR-140-5p/TLR4/NF-B axis.
FISH & SHELLFISH IMMUNOLOGY
(2022)
Article
Pharmacology & Pharmacy
Biljana Radovic, Nikola Stojilkovic, Marijana Curcic, Evica Antonijevic Miljakovic, Aleksandra Buha Dordevic, Dragana Vukelic Javorac, Katarina Baralic, Danijela Dukic-Cosic, Zorica Bulat, Biljana Antonijevic
Summary: This study aimed to assess the connection between a mixture of lead, cadmium, arsenic, methylmercury, and decabrominated diphenyl ether, and thyroid function, using a computational toxicogenomic approach. The study found that these chemicals were linked to thyroid diseases and identified several genes and pathways involved. Oxidative stress and inflammation were found to be the main mechanisms affected by this mixture.
Article
Environmental Sciences
Giulia Solazzo, Haotian Wu, Hannah E. Laue, Kasey Brennan, Julia M. Knox, Virginie Gillet, Amelie Bovin, Nadia Abdelouahab, Jonathan Posner, Elizabeth Raffanello, Sarah Pieper, Fredrick DuBois Bowman, Daniel Drake, Andrea A. Baccarelli, Larissa Takser
Summary: This study did not find a significant association between PBDE exposure and child cognitive and motor development. The impact of different PBDE concentrations during early and late pregnancy on children's neurodevelopment remains unclear.
ENVIRONMENTAL EPIDEMIOLOGY
(2021)
Article
Environmental Sciences
Giulia Solazzo, Haotian Wu, Hannah E. Laue, Kasey Brennan, Julia M. Knox, Virginie Gillet, Amelie Bovin, Nadia Abdelouahab, Jonathan Posner, Elizabeth Raffanello, Sarah Pieper, Fredrick DuBois Bowman, Daniel Drake, Andrea A. Baccarelli, Larissa Takser
Summary: This study investigated the association between PBDE concentration during early and late pregnancy and cognitive function in children aged 6-8 years. The results did not show a significant association between PBDE exposure and child cognitive and motor development.
ENVIRONMENTAL EPIDEMIOLOGY
(2021)
Article
Toxicology
Keith R. Shockley, June K. Dunnick
Summary: This study found that exposure to the chemical carcinogen PBDE induced liver transcriptomic changes associated with cancer, metabolism, membrane function, and Nrf2 antioxidant pathways at different life stages (infant, child, adult). Short-term exposure to PBDE resulted in upregulation of the Ras oncogenic pathway in adult rats, which was consistent with previous findings in PBDE-induced tumors. The use of gene expression profiling studies can help predict cancer endpoints in model studies and reduce reliance on traditional rodent cancer studies.
FRONTIERS IN TOXICOLOGY
(2023)
Review
Behavioral Sciences
Robert G. Mair, Rikki L. A. Miller, Benjamin A. Wormwood, Miranda J. Francoeur, Kristen D. Onos, Brett M. Gibson
NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS
(2015)
Review
Neurosciences
Kristen D. Onos, Stacey J. Sukoff Rizzo, Gareth R. Howell, Michael Sasnera
BRAIN RESEARCH BULLETIN
(2016)
Article
Geriatrics & Gerontology
Ileana Soto, Weronika A. Grabowska, Kristen D. Onos, Leah C. Graham, Harriet M. Jackson, Stephen N. Simeone, Gareth R. Howell
NEUROBIOLOGY OF AGING
(2016)
Article
Neurosciences
Vincent P. Markowski, Patrick Miller-Rhodes, Randy Cheung, Calla Goeke, Vincent Pecoraro, Gideon Cohen, Deena J. Small
NEUROTOXICOLOGY AND TERATOLOGY
(2017)
Article
Clinical Neurology
Chad A. Tagge, Andrew M. Fisher, Olga V. Minaeva, Amanda Gaudreau-Balderrama, Juliet A. Moncaster, Xiao-Lei Zhang, Mark W. Wojnarowicz, Noel Casey, Haiyan Lu, Olga N. Kokiko-Cochran, Sudad Saman, Maria Ericsson, Kristen D. Onos, Ronel Veksler, Vladimir V. Senatorov, Asami Kondo, Xiao Z. Zhou, Omid Miry, Linnea R. Vose, Katisha R. Gopaul, Chirag Upreti, Christopher J. Nowinski, Robert C. Cantu, Victor E. Alvarez, Audrey M. Hildebrandt, Erich S. Franz, Janusz Konrad, James A. Hamilton, Ning Hua, Yorghos Tripodis, Andrew T. Anderson, Gareth R. Howell, Daniela Kaufer, Garth F. Hall, Kun P. Lu, Richard M. Ransohoff, Robin O. Cleveland, Neil W. Kowall, Thor D. Stein, Bruce T. Lamb, Bertrand R. Huber, William C. Moss, Alon Friedman, Patric K. Stanton, Ann C. McKee, Lee E. Goldstein
Article
Pharmacology & Pharmacy
Robert G. Mair, Kristen D. Onos, Jacqueline R. Hembrook
Article
Neurosciences
Jacqueline R. Hembrook, Kristen D. Onos, Robert G. Mair
Article
Neurosciences
Vincent P. Markowski, Elizabeth A. Reeve, Kristen Onos, Mina Assadollahzadeh, Naomi McKay
NEUROTOXICOLOGY AND TERATOLOGY
(2012)
Article
Neurosciences
Patrick Miller-Rhodes, Maria Popescu, Calla Goeke, Toni Tirabassi, Lauren Johnson, Vincent P. Markowski
NEUROTOXICOLOGY AND TERATOLOGY
(2014)
Article
Multidisciplinary Sciences
Harriet M. Jackson, Kristen D. Onos, Keating W. Pepper, Leah C. Graham, Ellen C. Akeson, Candice Byers, Laura G. Reinholdt, Wayne N. Frankel, Gareth R. Howell
Article
Multidisciplinary Sciences
Kristen D. Onos, Miranda J. Francoeur, Benjamin A. Wormwood, Rikki L. A. Miller, Brett M. Gibson, Robert G. Mair
Article
Genetics & Heredity
Kristen D. Onos, Asli Uyar, Kelly J. Keezer, Harriet M. Jackson, Christoph Preuss, Casey J. Acklin, Rita O'Rourke, Rebecca Buchanan, Travis L. Cossette, Stacey J. Sukoff Rizzo, Ileana Soto, Gregory W. Carter, Gareth R. Howell