BRAF activates and physically interacts with PAK to regulate cell motility

TERTPromoter Mutations and Their Association withBRAFV600E Mutation and Aggressive Clinicopathological Characteristics of Thyroid Cancer

(2014) Xiaoli Liu et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Association Between BRAF V600E Mutation and Mortality in Patients With Papillary Thyroid Cancer

(2013) Mingzhao Xing et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

p21-Activated Kinase 1 (PAK1) Can Promote ERK Activation in a Kinase-independent Manner

(2013) Zhipeng Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Localization of CaSR Antagonists in CaSR-expressing Medullary Thyroid Cancer

(2013) Haiming Ding et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Frequent SomaticTERTPromoter Mutations in Thyroid Cancer: Higher Prevalence in Advanced Forms of the Disease

(2013) Iñigo Landa et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

PAK1 Regulates Breast Cancer Cell Invasion through Secretion of Matrix Metalloproteinases in Response to Prolactin and Three-Dimensional Collagen IV

(2013) Leah Rider et al.   MOLECULAR ENDOCRINOLOGY

Relief of Feedback Inhibition of HER3 Transcription by RAF and MEK Inhibitors Attenuates Their Antitumor Effects in BRAF -Mutant Thyroid Carcinomas

(2013) Cristina Montero-Conde et al.   Cancer Discovery

Vemurafenib enhances MHC induction inBRAFV600Ehomozygous melanoma cells

(2013) Bishu Sapkota et al.   OncoImmunology

STRING v9.1: protein-protein interaction networks, with increased coverage and integration

(2012) Andrea Franceschini et al.   NUCLEIC ACIDS RESEARCH

Comparison with Published Systems of a New Staging System for Papillary and Follicular Thyroid Carcinoma

(2012) Ronnie Meiyi Wong et al.   THYROID

Oncogenic BRAF Induces Melanoma Cell Invasion by Downregulating the cGMP-Specific Phosphodiesterase PDE5A

(2011) Imanol Arozarena et al.   CANCER CELL

BRAFV600E and Microenvironment in Thyroid Cancer: A Functional Link to Drive Cancer Progression

(2011) C. Nucera et al.   CANCER RESEARCH

Small-molecule MAPK inhibitors restore radioiodine incorporation in mouse thyroid cancers with conditional BRAF activation

(2011) Debyani Chakravarty et al.   JOURNAL OF CLINICAL INVESTIGATION

BRAF and RAS oncogenes regulate Rho GTPase pathways to mediate migration and invasion properties in human colon cancer cells: a comparative study

(2011) Eleni Makrodouli et al.   Molecular Cancer

PAK1 is a breast cancer oncogene that coordinately activates MAPK and MET signaling

(2011) Y Shrestha et al.   ONCOGENE

Progression of BRAF-induced thyroid cancer is associated with epithelial–mesenchymal transition requiring concomitant MAP kinase and TGFβ signaling

(2011) J A Knauf et al.   ONCOGENE

Targeting p21-activated kinase 1 (PAK1) to induce apoptosis of tumor cells

(2011) C. C. Ong et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Molecular markers of aggressiveness of thyroid cancer

(2011) Matthew D Ringel   Current Opinion in Endocrinology Diabetes and Obesity

Group I p21-activated kinases regulate thyroid cancer cell migration and are overexpressed and activated in thyroid cancer invasion

(2010) Samantha K McCarty et al.   ENDOCRINE-RELATED CANCER

Signalling to cancer cell invasion through PAK family kinases

(2010) Andrew Whale   Frontiers in Bioscience-Landmark

The BRAFV600E Oncogene Induces Transforming Growth Factor   Secretion Leading to Sodium Iodide Symporter Repression and Increased Malignancy in Thyroid Cancer

(2009) G. Riesco-Eizaguirre et al.   CANCER RESEARCH

PAK kinase regulates Rac GTPase and is a potential target in human schwannomas

(2009) Christine Flaiz et al.   EXPERIMENTAL NEUROLOGY

Phase II Trial of Sorafenib in Metastatic Thyroid Cancer

(2009) Richard T. Kloos et al.   JOURNAL OF CLINICAL ONCOLOGY

Signaling dynamics of the KSR1 scaffold complex

(2009) M. M. McKay et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Molecular pathology of thyroid cancer: diagnostic and clinical implications

(2008) James A. Fagin et al.   BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM

Scaffolding function of PAK in the PDK1–Akt pathway

(2008) Maiko Higuchi et al.   NATURE CELL BIOLOGY

Colocalization of fluorescent markers in confocal microscope images of plant cells

(2008) Andrew P French et al.   Nature Protocols

Human Protein Reference Database--2009 update

(2008) T. S. Keshava Prasad et al.   NUCLEIC ACIDS RESEARCH