IGF1 dependence of dietary energy balance effects on murine Met1 mammary tumor progression, epithelial-to-mesenchymal transition, and chemokine expression

Dietary Energy Balance Modulates Epithelial-to-Mesenchymal Transition and Tumor Progression in Murine Claudin-Low and Basal-like Mammary Tumor Models

(2012) S. M. Dunlap et al.   Cancer Prevention Research

Small Interfering RNA Targeted to IGF-IR Delays Tumor Growth and Induces Proinflammatory Cytokines in a Mouse Breast Cancer Model

(2012) Tiphanie Durfort et al.   PLoS One

Postmenopausal obesity promotes tumor angiogenesis and breast cancer progression in mice

(2011) Jian-Wei Gu et al.   CANCER BIOLOGY & THERAPY

Genetic Reduction of Insulin-like Growth Factor-1 Mimics the Anticancer Effects of Calorie Restriction on Cyclooxygenase-2–Driven Pancreatic Neoplasia

(2011) Laura M. Lashinger et al.   Cancer Prevention Research

Obesity Is Associated with Inflammation and Elevated Aromatase Expression in the Mouse Mammary Gland

(2011) K. Subbaramaiah et al.   Cancer Prevention Research

IGF-1 increases invasive potential of MCF 7 breast cancer cells and induces activation of latent TGF-β1 resulting in epithelial to mesenchymal transition

(2011) Logan A Walsh et al.   Cell Communication and Signaling

Ob/ob serum promotes a mesenchymal cell phenotype in B16BL6 melanoma cells

(2011) Kyoko Kushiro et al.   CLINICAL & EXPERIMENTAL METASTASIS

Decreased IGF Type 1 Receptor Signaling in Mammary Epithelium during Pregnancy Leads to Reduced Proliferation, Alveolar Differentiation, and Expression of Insulin Receptor Substrate (IRS)-1 and IRS-2

(2011) Zhaoyu Sun et al.   ENDOCRINOLOGY

CCN6 (WISP3) decreases ZEB1-mediated EMT and invasion by attenuation of IGF-1 receptor signaling in breast cancer

(2011) G. Lorenzatti et al.   JOURNAL OF CELL SCIENCE

Integrated miRNA and mRNA expression profiling of mouse mammary tumor models identifies miRNA signatures associated with mammary tumor lineage

(2011) Min Zhu et al.   GENOME BIOLOGY

Insulin-Like Growth Factor-I Regulates the Liver Microenvironment in Obese Mice and Promotes Liver Metastasis

(2010) Y. Wu et al.   CANCER RESEARCH

High IGF-IR Activity in Triple-Negative Breast Cancer Cell Lines and Tumorgrafts Correlates with Sensitivity to Anti-IGF-IR Therapy

(2010) B. C. Litzenburger et al.   CLINICAL CANCER RESEARCH

Energy Balance, Host-Related Factors, and Cancer Progression

(2010) Stephen D. Hursting et al.   JOURNAL OF CLINICAL ONCOLOGY

Gene expression profiling identifies activated growth factor signaling in poor prognosis (Luminal-B) estrogen receptor positive breast cancer

(2009) Sherene Loi et al.   BMC Medical Genomics

A Gene Expression Signature Associated with “K-Ras Addiction” Reveals Regulators of EMT and Tumor Cell Survival

(2009) Anurag Singh et al.   CANCER CELL

Calories and carcinogenesis: lessons learned from 30 years of calorie restriction research

(2009) S. D. Hursting et al.   CARCINOGENESIS

Antitumor Activity of GSK1904529A, a Small-molecule Inhibitor of the Insulin-like Growth Factor-I Receptor Tyrosine Kinase

(2009) P. Sabbatini et al.   CLINICAL CANCER RESEARCH

Lessons in Signaling and Tumorigenesis from Polyomavirus Middle T Antigen

(2009) M. M. Fluck et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Genetic reduction of circulating insulin-like growth factor-1 inhibits azoxymethane-induced colon tumorigenesis in mice

(2009) Susan E. Olivo-Marston et al.   MOLECULAR CARCINOGENESIS

Emerging role of insulin-like growth factor receptor inhibitors in oncology: early clinical trial results and future directions

(2009) A Gualberto et al.   ONCOGENE

Dietary Energy Balance Modulates Signaling through the Akt/Mammalian Target of Rapamycin Pathways in Multiple Epithelial Tissues

(2008) Tricia Moore et al.   Cancer Prevention Research

Phosphorylated Insulin-Like Growth Factor-I/Insulin Receptor Is Present in All Breast Cancer Subtypes and Is Related to Poor Survival

(2008) J. H. Law et al.   CANCER RESEARCH

Insulin-like Growth Factor-I-Dependent Up-regulation of ZEB1 Drives Epithelial-to-Mesenchymal Transition in Human Prostate Cancer Cells

(2008) T. R. Graham et al.   CANCER RESEARCH

Reduced Susceptibility to Two-Stage Skin Carcinogenesis in Mice with Low Circulating Insulin-Like Growth Factor I Levels

(2008) T. Moore et al.   CANCER RESEARCH

Murine osteosarcoma primary tumour growth and metastatic progression is maintained after marked suppression of serum insulin-like growth factor I

(2008) Sung-Hyeok Hong et al.   INTERNATIONAL JOURNAL OF CANCER

CCL2 Protects Prostate Cancer PC3 Cells from Autophagic Death via Phosphatidylinositol 3-Kinase/AKT-dependent Survivin Up-regulation

(2008) Hernan Roca et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Leptin affects endocardial cushion formation by modulating EMT and migration via Akt signaling cascades

(2008) Anjali K. Nath et al.   JOURNAL OF CELL BIOLOGY

Obesity Accelerates Mouse Mammary Tumor Growth in the Absence of Ovarian Hormones

(2008) Nomelí P. Núñez et al.   NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL