Article
Geriatrics & Gerontology
Koji Sakamaki, Katsuhiko Tsunekawa, Nobuyoshi Ishiyama, Mizuho Kudo, Kimiko Ando, Masako Akuzawa, Katsuyuki Nakajima, Yohnosuke Shimomura, Osamu Araki, Takao Kimura, Masami Murakami
Summary: Serum TSH concentration may be associated with carotid atherosclerosis in euthyroid women without cardiovascular diseases and metabolic disorders, especially in postmenopausal women. A concentration of TSH >= 2.5 mu IU/mL could be a useful indicator for assessing the risk of atherosclerosis in this population.
Article
Biology
Guang-Quan Zhou, Hao Wei, Xiaoyi Wang, Kai-Ni Wang, Yuzhao Chen, Fei Xiong, Guanqing Ren, Chunying Liu, Le Li, Qinghua Huang
Summary: In this work, we propose an end-to-end boundary-salience multi-branch network, BSMNet, to identify the carotid intima-media from ultrasound images. Our method exploits prior shape knowledge and anatomical dependence to improve the accuracy of boundary identification and incorporates a strip attention model for segmenting thin strip regions. Experimental results demonstrate the promising performance of our method, achieving about 0.02 improvement in Dice and HD95 compared to other state-of-the-art methods. Our method is expected to advance the analysis of systemic arterial disease with ultrasound imaging.
COMPUTERS IN BIOLOGY AND MEDICINE
(2023)
Article
Cardiac & Cardiovascular Systems
Wendy Wang, Faye L. Norby, Kristen M. George, Alvaro Alonso, Thomas H. Mosley, Rebecca F. Gottesman, Michelle L. Meyer, Pamela L. Lutsey
Summary: The study found that higher levels of carotid intima-media thickness and interadventitial diameter in midlife are associated with an increased risk of dementia, while the presence of carotid plaque did not show a significant association. Higher distensibility was associated with a lower risk of dementia.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2021)
Article
Nutrition & Dietetics
Christopher Morrissey, Marie-Josephe Amiot, Aurelie Goncalves, Cecile Raverdy, Delphine Masson, Catherine Tardivel, Sandrine Gayrard, Myriam Carrere, Jean-Francois Landrier, Agnes Vinet, Antonia Perez-Martin
Summary: This study assessed the effects of vitamin D supplementation on arterial stiffness in obese adolescents. The researchers found that a high proportion of obese adolescents had vitamin D deficiency and supplementation improved carotid intima-media thickness (IMT) and reduced the risk of arterial stiffness.
Article
Biochemistry & Molecular Biology
Daniela Efremova, Natalia Ciobanu, Danu Glavan, Pavel Leahu, Renata Racila, Tatiana Balanua, Alexandru Matei, Maria Vasilieva, Cristina Cheptea, Paula Bitca, Cristina Damian, Ana Bondarciuc, Irina Bejenari, Adelina Cojocaru, Diana Manea, Mihail Ciocanu, Eremei Zota, Dumitru Ciolac, Stanislav A. Groppa
Summary: This study aims to evaluate the interrelations between serum urate (SU) levels and carotid atherosclerosis in subjects with different obesity phenotypes. The results showed that subjects with central obesity and mixed obesity had higher SU levels and markers of carotid atherosclerosis compared to subjects with general obesity and non-obese individuals.
Article
Medicine, General & Internal
Engelbert A. Nonterah, Daniel Boateng, Nigel J. Crowther, Kerstin Klipstein-Grobusch, Abraham R. Oduro, Godfred Agongo, Shukri F. Mohamed, Palwende R. Boua, Solomon S. R. Choma, Shane A. Norris, Stephen M. Tollman, Michiel L. Bots, Michele Ramsay, Diederick Grobbee
Summary: This study evaluated the association of carotid atherosclerosis and microalbuminuria with 10-year ASCVD risk in middle-aged individuals in sub-Saharan Africa. The results showed that microalbuminuria measured by SUA may indicate risk of subclinical carotid atherosclerosis and high 10-year ASCVD risk.
Article
Cardiac & Cardiovascular Systems
Xue Bao, Biao Xu, Lars Lind, Gunnar Engstrom
Summary: Subclinical carotid atherosclerosis is an important factor in cardiovascular risk estimation by SCORE2. Carotid ultrasound improves the predictive performance of SCORE2 for cardiovascular risk assessment. SCORE2 may over-predict the risk in individuals without carotid plaque and under-predict the risk in those with carotid plaque.
EUROPEAN JOURNAL OF PREVENTIVE CARDIOLOGY
(2023)
Article
Medicine, General & Internal
Magdalena Szychlinska, Magdalena Rzeczkowska, Katarzyna Gontarz-Nowak, Wojciech Matuszewski, Elzbieta Bandurska-Stankiewicz
Summary: Compared to the general population, people with adrenal incidentalomas (AIs) have a higher prevalence of obesity, hypertension, impaired carbohydrate and lipid metabolism. This study aimed to investigate the association between non-functioning adrenal incidentalomas (NFAIs), metabolic profile, and carotid intima-media thickness (CIMT) as a predictor of atherosclerosis. The results showed that patients with NFAIs had higher waist circumference, blood pressure, fasting insulin, glucose levels, and CIMT compared to the control group. These findings suggest that patients with NFAIs exhibit a range of metabolic abnormalities.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Clinical Neurology
Naomi Vidal Ferreira, Laiss Bertola, Itamar S. S. Santos, Alessandra C. C. Goulart, Marcio S. S. Bittencourt, Sandhi Maria Barreto, Luana Giatti, Paulo Caramelli, Alexandre Pereira, Paulo Andrade Lotufo, Isabela M. M. Bensenor, Claudia Kimie Suemoto
Summary: Carotid intima-media thickness (cIMT) is associated with cognitive decline, with a stronger association in White than in Black participants. This study highlights the importance of considering race when assessing the relationship between cIMT and cognitive decline.
ALZHEIMERS & DEMENTIA
(2023)
Review
Health Care Sciences & Services
Anna Maria Rychter, Dariusz Naskret, Agnieszka Zawada, Alicja Ewa Ratajczak, Agnieszka Dobrowolska, Iwona Krela-Kazmierczak
Summary: Atherosclerosis is strongly associated with obesity, with carotid intima-media thickness (cIMT) serving as a predictor of cardiovascular events and subclinical atherosclerosis. Behavioral interventions can directly impact cIMT values, influencing cardiovascular disease risk.
JOURNAL OF PERSONALIZED MEDICINE
(2021)
Article
Biochemistry & Molecular Biology
Valeria Sutti Nunes, Edite Vieira Silva de Campos, Jamal Baracat, Victor Franca, Erica Ivana Lazaro Gomes, Raissa Peres Coelho, Edna Regina Nakandakare, Vanessa Helena Souza Zago, Eliana Cotta de Faria, Eder Carlos Rocha Quintao
Summary: This study investigated the relationships between plasma cholesterol synthesis and absorption markers and cardiovascular disease risk factors, cIMT, and carotid plaques in asymptomatic subjects. The findings suggested that campesterol may be associated with atherosclerotic plaques, while the ratios of lathosterol/campesterol or lathosterol/sitosterol may indicate an inverse association. This highlights the inverse relationship between cholesterol synthesis and absorption, with the absorption marker campesterol reflecting changes in body cholesterol homeostasis and atherosclerotic potential.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Endocrinology & Metabolism
Gulsah Elbuken, Cihan Aydin, Beyza Olcay Ozturk, Huseyin Aykac, Birol Topcu, Sayid Shafi Zuhur
Summary: This study found that patients with normocalcaemic hyperparathyroidism had greater intima-media thickness of the carotid artery compared to the control group, indicating an increased risk of atherosclerosis. Normocalcaemic hyperparathyroidism may be associated with cardiovascular diseases.
ENDOKRYNOLOGIA POLSKA
(2023)
Article
Cardiac & Cardiovascular Systems
Weijie Cao, Yiting Xu, Yun Shen, Tingting Hu, Yufei Wang, Xiaojing Ma, Yuqian Bao
Summary: This study investigated the relationship between neck circumference (NC), carotid intima-media thickness (C-IMT), and carotid plaque. The results showed that higher NC was significantly associated with an increased risk of carotid plaque and elevated C-IMT.
NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES
(2022)
Article
Cardiac & Cardiovascular Systems
Evangelos Oikonomou, George Lazaros, Vasiliki Chara Mystakidi, Nikolaos Papaioannou, Panagiotis Theofilis, Georgia Vogiatzi, Christos Chasikidis, Petros Fountoulakis, Maria-Argentina Papakostantinou, Margarita Niki Assimakopoulos, Nikolaos Barmparesos, Panagiotis Tasios, Juan C. Kaski, Dimitris Tousoulis
Summary: The study demonstrates that residents in areas with high concentrations of gaseous air pollutants have increased carotid atherosclerotic burden and inflammation compared to residents in other regions. High levels of CO, NO2, and SO2 were observed in Region 4, where individuals also showed higher levels of C reactive protein and greater carotid plaque burden. Additionally, the propensity score analysis indicated higher differences in mean cIMT among individuals with coronary artery disease in high pollution areas compared to low pollution areas.
INTERNATIONAL JOURNAL OF CARDIOLOGY
(2021)
Article
Multidisciplinary Sciences
Hye Jeong Kim, Seong Soon Kwon, Sang Joon Park, Dong Won Byun, Kyoil Suh, Myung Hi Yoo, Duk Won Bang, Hyeong Kyu Park
Summary: This study suggests that the TyG index and thyroid function status are important predictors of carotid plaque risk in healthy individuals. Early evaluation of carotid plaques may be necessary for patients with high insulin resistance and subclinical hypothyroidism.
