Review
Pathology
Soo-Ryum Yang, Mary B. Beasley, Andrew Churg, Thomas V. Colby, Evans R. Fernandez Perez, David Lynch, Nestor L. Muller, William D. Travis
Summary: Assessment of lung biopsies for the diagnosis of hypersensitivity pneumonitis (HP) is challenging. The American College of Chest Physicians has published guidelines for the diagnosis of HP to address these challenges. This review explores the multidisciplinary diagnostic evaluation of HP, highlighting histologic features and the correlation of lung biopsies with computed tomography findings.
AMERICAN JOURNAL OF SURGICAL PATHOLOGY
(2022)
Article
Medicine, General & Internal
Takayuki Yamaji, Takahiro Harada, Yu Hashimoto, Yuji Takaeko, Masato Kajikawa, Yiming Han, Tatsuya Maruhashi, Shinji Kishimoto, Haruki Hashimoto, Yasuki Kihara, Eisuke Hida, Kazuaki Chayama, Chikara Goto, Farina Mohamad Yusoff, Ayumu Nakashima, Yukihito Higashi
Summary: This study aimed to investigate the relationship between HbA1c levels and vascular function in patients with type 2 diabetes. Results showed an inverted U-shaped pattern of association between HbA1c levels and FMD, with FMD being significantly smaller in patients with low HbA1c levels. There were no significant differences in NID values among the groups.
Article
Engineering, Electrical & Electronic
Namho Kim, Da Young Lee, Wonju Seo, Nan Hee Kim, Sung-Min Park
Summary: The study aimed to develop clustering-based personalized models to estimate hemoglobin A1c (HbA1c) levels from continuous glucose monitoring (CGM) values. The proposed models showed improved performance in estimating HbA1c levels and provided real-time integrated information for better glycemic control.
IEEE SENSORS JOURNAL
(2022)
Article
Sport Sciences
Jill A. Kanaley, Sheri R. Colberg, Matthew H. Corcoran, Steven K. Malin, Nancy R. Rodriguez, Carlos J. Crespo, John P. Kirwan, Juleen R. Zierath
Summary: This consensus statement updates the 2010 position on exercise and type 2 diabetes, providing a brief summary of current evidence and extending the prior recommendations. It highlights the importance of physical activity for health and glycemic management in individuals with type 2 diabetes and offers specific recommendations.
MEDICINE & SCIENCE IN SPORTS & EXERCISE
(2022)
Article
Medicine, General & Internal
Jencia Wong, Glynis P. Ross, Sophia Zoungas, Maria E. Craig, Elizabeth A. Davis, Kim C. Donaghue, Louise J. Maple-Brown, Margaret J. McGill, Jonathan E. Shaw, Jane Speight, Natalie Wischer, Stephen Stranks
Summary: Type 2 diabetes in young adults is a more aggressive condition than in older individuals, with higher risks of complications and early mortality. This first Australian consensus statement provides recommendations specifically for managing type 2 diabetes in young adults, addressing areas where existing guidance for older adults may not be suitable. The statement covers various aspects of care, including screening, diabetes type, lifestyle, medication, and cardiovascular disease risk management.
MEDICAL JOURNAL OF AUSTRALIA
(2022)
Article
Endocrinology & Metabolism
Paul R. Conlin, Libin Zhang, Donglin Li, Richard E. Nelson, Julia C. Prentice, David C. Mohr
Summary: The treatment goals for hemoglobin A1c (A1c) in older adults should be personalized to balance risks and benefits. It is uncertain if stability of A1c within target ranges affects adverse outcomes.
BMJ OPEN DIABETES RESEARCH & CARE
(2023)
Article
Endocrinology & Metabolism
Xu Huang, Cheng Qin, Xiaoxu Guo, Feng Cao, Chengchun Tang
Summary: This study investigated the relationship between HbA1c and the incidence of hypertension in a large prospective cohort. The findings suggest that HbA1c is linearly and positively associated with the risk of hypertension, particularly in female, lower education level, and non-obese subgroups. HbA1c can be considered as a predictor for hypertension risk.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Article
Medicine, General & Internal
Muhammad Abu Tailakh, Shlomo-yaron Ishay, Jenan Awesat, Liat Poupko, Gidon Sahar, Victor Novack
Summary: The study found that diabetes patients with HbA1c levels above 7% before coronary artery bypass grafting are at higher risk for long-term mortality, especially late mortality; while patients with HbA1c levels below 7% have a relatively lower mortality rate.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Endocrinology & Metabolism
Guanhua Chen, Rui Zhang, Chunlu Tan, Xubao Liu, Lei Yu, Yonghua Chen
Summary: Using HbA1c alone as a diagnostic criterion for diabetes may not be sensitive enough in patients with pancreatic diseases. The optimal values of 5.8% and 6.0% for HbA1c improved the accuracy of diagnosing prediabetes and diabetes and should be considered. Furthermore, combining HbA1c and FPG tests is advocated for diagnosing diabetes in patients with pancreatic diseases.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Article
Medicine, General & Internal
Alexandra Halalau, Sujoy Roy, Arpitha Hegde, Sumesh Khanal, Emily Langnas, Maidah Raja, Ramin Homayouni
Summary: This study aimed to determine the risk factors associated with rapid progression from normal or prediabetic hemoglobin A1c levels to type 2 diabetes mellitus. The results showed that progression to diabetes within a four-year period is associated with baseline BMI. A steady rise in HbA1c during the same period is associated with age and family history of type 2 diabetes, while rapid rise in HbA1c is associated with age and personal history of major cardiovascular events.
ANNALS OF MEDICINE
(2023)
Article
Endocrinology & Metabolism
Sabaa Joad, Elliot Ballato, F. N. U. Deepika, Giulia Gregori, Alcibiades Leonardo Fleires-Gutierrez, Georgia Colleluori, Lina Aguirre, Rui Chen, Vittoria Russo, Virginia Carolina Fuenmayor Lopez, Clifford Qualls, Dennis T. Villareal, Reina Armamento-Villareal
Summary: The study aims to identify a hemoglobin A1c threshold level by which reduction in bone turnover begins in men with type 2 diabetes mellitus. Results show that an A1c level of 7% or greater is associated with lower bone turnover in the study population and specifically in men with T2D.
FRONTIERS IN ENDOCRINOLOGY
(2021)
Article
Endocrinology & Metabolism
Ying Wei, Zhenyu Wu, Ying Wang, Guang Wang, Jia Liu
Summary: The study found that the hemoglobin glycation index (HGI) is associated with sex and diabetes, with glycemic control in women with diabetes being negatively correlated with serum uric acid levels, while blood glucose and HGI in women without diabetes are positively correlated with serum uric acid levels. The relationship between serum uric acid levels in men with prediabetes and glycated hemoglobin is bell-shaped.
DIABETOLOGY & METABOLIC SYNDROME
(2022)
Article
Endocrinology & Metabolism
Seema Kumar, Ambika P. Ashraf, Aida Lteif, Jane Lynch, Tandy Aye
Summary: The study revealed that the main factors influencing the decision to choose pediatric endocrinology as a career include intellectual stimulation, exposure to endocrinology, and the ability to establish relationships with patients with chronic disorders. Most pediatric endocrinologists were satisfied with the intellectual stimulation in their specialty, but dissatisfaction with financial compensation. Majority of them were satisfied with their work environment, but reported a relatively high level of work-related stress.
ENDOCRINE PRACTICE
(2021)
Article
Pathology
Lee H. Hilborne, Caixia Bi, Jeff Radcliff, Martin H. Kroll, Harvey W. Kaufman
Summary: Although many health plans do not cover HbA1c testing for diabetes screening, more than 1 in 4 glucose screening patients 60 years of age or older with an in-range glucose result had a concurrent elevated HbA(1c) result.
AMERICAN JOURNAL OF CLINICAL PATHOLOGY
(2022)
Article
Endocrinology & Metabolism
Katherine A. Sauder, Jeanette M. Stafford, Shelley Ehrlich, Jean M. Lawrence, Angela D. Liese, Santica Marcovina, Amy K. Mottl, Catherine Pihoker, Sharon Saydah, Amy S. Shah, Ralph B. D'Agostino, Dana Dabelea
Summary: Disparities in HbA(1c) testing frequency were observed primarily based on health care-related factors, which were associated with diabetes outcomes in type 1 diabetes. Higher frequency of HbA(1c) testing was linked to lower HbA(1c) levels and decreased odds of microvascular complications over time. However, these associations were attenuated after adjusting for HbA(1c) testing correlates.
