标题
Innate immune signalling at the intestinal epithelium in homeostasis and disease
作者
关键词
-
出版物
EMBO REPORTS
Volume 13, Issue 8, Pages 684-698
出版商
Wiley
发表日期
2012-07-17
DOI
10.1038/embor.2012.96
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Reciprocal Expression and Signaling of TLR4 and TLR9 in the Pathogenesis and Treatment of Necrotizing Enterocolitis
- (2014) S. C. Gribar et al. JOURNAL OF IMMUNOLOGY
- Enterocyte-Derived TAK1 Signaling Prevents Epithelium Apoptosis and the Development of Ileitis and Colitis
- (2014) R. Kajino-Sakamoto et al. JOURNAL OF IMMUNOLOGY
- Loss of Epithelial RelA Results in Deregulated Intestinal Proliferative/Apoptotic Homeostasis and Susceptibility to Inflammation
- (2014) K. A. Steinbrecher et al. JOURNAL OF IMMUNOLOGY
- Autophagy in the intestinal epithelium regulates Citrobacter rodentium infection
- (2012) Jun Inoue et al. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
- Salmonella Gut Invasion Involves TTSS-2-Dependent Epithelial Traversal, Basolateral Exit, and Uptake by Epithelium-Sampling Lamina Propria Phagocytes
- (2012) Andreas J. Müller et al. Cell Host & Microbe
- Lack of Intestinal Epithelial Atg7 Affects Paneth Cell Granule Formation but Does Not Compromise Immune Homeostasis in the Gut
- (2012) Nadine Wittkopf et al. Clinical & Developmental Immunology
- Enterocyte Microvillus-Derived Vesicles Detoxify Bacterial Products and Regulate Epithelial-Microbial Interactions
- (2012) David A. Shifrin et al. CURRENT BIOLOGY
- Enterocyte STAT5 promotes mucosal wound healing via suppression of myosin light chain kinase-mediated loss of barrier function and inflammation
- (2012) Shila Gilbert et al. EMBO Molecular Medicine
- Oxidized Mitochondrial DNA Activates the NLRP3 Inflammasome during Apoptosis
- (2012) Kenichi Shimada et al. IMMUNITY
- Epithelial Cell-Intrinsic Notch Signaling Plays an Essential Role in the Maintenance of Gut Immune Homeostasis
- (2012) Y. Obata et al. JOURNAL OF IMMUNOLOGY
- Cytosolic flagellin receptor NLRC4 protects mice against mucosal and systemic challenges
- (2012) F A Carvalho et al. Mucosal Immunology
- Lenses on biology
- (2012) Herb Brody et al. NATURE
- Age-Dependent TLR3 Expression of the Intestinal Epithelium Contributes to Rotavirus Susceptibility
- (2012) Johanna Pott et al. PLoS Pathogens
- Intestinal epithelial-specific PTEN inactivation results in tumor formation
- (2011) Do-Sun Byun et al. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
- NLRP6 Inflammasome Regulates Colonic Microbial Ecology and Risk for Colitis
- (2011) Eran Elinav et al. CELL
- The PepT1–NOD2 Signaling Pathway Aggravates Induced Colitis in Mice
- (2011) Guillaume Dalmasso et al. GASTROENTEROLOGY
- The Nod2 Sensor Promotes Intestinal Pathogen Eradication via the Chemokine CCL2-Dependent Recruitment of Inflammatory Monocytes
- (2011) Yun-Gi Kim et al. IMMUNITY
- Biochemical and histological changes in the small intestine of mice with dextran sulfate sodium colitis
- (2011) Roger Yazbeck et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Induction of Paneth cell degranulation by orally administered Toll-like receptor ligands
- (2011) Cristiano Rumio et al. JOURNAL OF CELLULAR PHYSIOLOGY
- CD98 expression modulates intestinal homeostasis, inflammation, and colitis-associated cancer in mice
- (2011) Hang Thi Thu Nguyen et al. JOURNAL OF CLINICAL INVESTIGATION
- Constitutive intestinal NF-κB does not trigger destructive inflammation unless accompanied by MAPK activation
- (2011) Monica Guma et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Nucleotide-Binding Oligomerization Domain 1 Mediates Recognition of Clostridium difficile and Induces Neutrophil Recruitment and Protection against the Pathogen
- (2011) M. Hasegawa et al. JOURNAL OF IMMUNOLOGY
- A Functional Role for Nlrp6 in Intestinal Inflammation and Tumorigenesis
- (2011) G. Y. Chen et al. JOURNAL OF IMMUNOLOGY
- Toll-Like Receptors as Interferon-Regulated Genes and Their Role in Disease
- (2011) Jing Jing Khoo et al. JOURNAL OF INTERFERON AND CYTOKINE RESEARCH
- FADD prevents RIP3-mediated epithelial cell necrosis and chronic intestinal inflammation
- (2011) Patrick-Simon Welz et al. NATURE
- Caspase-8 regulates TNF-α-induced epithelial necroptosis and terminal ileitis
- (2011) Claudia Günther et al. NATURE
- IL-17RE is the functional receptor for IL-17C and mediates mucosal immunity to infection with intestinal pathogens
- (2011) Xinyang Song et al. NATURE IMMUNOLOGY
- IL-17C regulates the innate immune function of epithelial cells in an autocrine manner
- (2011) Vladimir Ramirez-Carrozzi et al. NATURE IMMUNOLOGY
- Crosstalk between B lymphocytes, microbiota and the intestinal epithelium governs immunity versus metabolism in the gut
- (2011) Natalia Shulzhenko et al. NATURE MEDICINE
- Identification of an innate T helper type 17 response to intestinal bacterial pathogens
- (2011) Kaoru Geddes et al. NATURE MEDICINE
- Paneth cells, antimicrobial peptides and maintenance of intestinal homeostasis
- (2011) Charles L. Bevins et al. NATURE REVIEWS MICROBIOLOGY
- TNFAIP3 Maintains Intestinal Barrier Function and Supports Epithelial Cell Tight Junctions
- (2011) Lauren E. Kolodziej et al. PLoS One
- IFN- determines the intestinal epithelial antiviral host defense
- (2011) J. Pott et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The transcriptional repressor Blimp1/Prdm1 regulates postnatal reprogramming of intestinal enterocytes
- (2011) J. Harper et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Nod-like receptor pyrin domain-containing protein 6 (NLRP6) controls epithelial self-renewal and colorectal carcinogenesis upon injury
- (2011) S. Normand et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Nucleotide oligomerization domain-containing proteins instruct T cell helper type 2 immunity through stromal activation
- (2011) J. G. Magalhaes et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The Antibacterial Lectin RegIII Promotes the Spatial Segregation of Microbiota and Host in the Intestine
- (2011) S. Vaishnava et al. SCIENCE
- Blimp1 regulates the transition of neonatal to adult intestinal epithelium
- (2011) Vanesa Muncan et al. Nature Communications
- Disparate Effects of Bacteria and Toll-Like Receptor-Dependant Bacterial Ligand Stimulation on Immunoglobulin A Transcytosis
- (2011) Lawrence N. Diebel et al. JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE
- miR-146a Mediates Protective Innate Immune Tolerance in the Neonate Intestine
- (2010) Cécilia Chassin et al. Cell Host & Microbe
- Epithelial-specific blockade of MyD88-dependent pathway causes spontaneous small intestinal inflammation
- (2010) Jianfeng Gong et al. CLINICAL IMMUNOLOGY
- Commensal microflora and interferon-γ promote steady-state interleukin-7 production in vivo
- (2010) Shabnam Shalapour et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- MicroRNAs Control Intestinal Epithelial Differentiation, Architecture, and Barrier Function
- (2010) Lindsay B. McKenna et al. GASTROENTEROLOGY
- Pathogenic and Protective Roles of MyD88 in Leukocytes and Epithelial Cells in Mouse Models of Inflammatory Bowel Disease
- (2010) Mark J. Asquith et al. GASTROENTEROLOGY
- Distinct Effects of p38α Deletion in Myeloid Lineage and Gut Epithelia in Mouse Models of Inflammatory Bowel Disease
- (2010) Motoyuki Otsuka et al. GASTROENTEROLOGY
- Colitis induced in mice with dextran sulfate sodium (DSS) is mediated by the NLRP3 inflammasome
- (2010) C. Bauer et al. GUT
- The NLRP3 Inflammasome Protects against Loss of Epithelial Integrity and Mortality during Experimental Colitis
- (2010) Md. Hasan Zaki et al. IMMUNITY
- Cell-Cell Propagation of NF-κB Transcription Factor and MAP Kinase Activation Amplifies Innate Immunity against Bacterial Infection
- (2010) Christoph Alexander Kasper et al. IMMUNITY
- Nod1 and Nod2 Regulation of Inflammation in the Salmonella Colitis Model
- (2010) K. Geddes et al. INFECTION AND IMMUNITY
- NLRP3 inflammasome plays a key role in the regulation of intestinal homeostasis
- (2010) Simon A. Hirota et al. INFLAMMATORY BOWEL DISEASES
- Constitutive activation of epithelial TLR4 augments inflammatory responses to mucosal injury and drives colitis-associated tumorigenesis
- (2010) Masayuki Fukata et al. INFLAMMATORY BOWEL DISEASES
- Quantitative expression of RIG-like helicase, NOD-like receptor and inflammasome-related mRNAs in humans and mice
- (2010) M. Lech et al. INTERNATIONAL IMMUNOLOGY
- Caveolin-1–dependent occludin endocytosis is required for TNF-induced tight junction regulation in vivo
- (2010) Amanda M. Marchiando et al. JOURNAL OF CELL BIOLOGY
- Enterocyte-specific A20 deficiency sensitizes to tumor necrosis factor–induced toxicity and experimental colitis
- (2010) Lars Vereecke et al. JOURNAL OF EXPERIMENTAL MEDICINE
- The NLRP3 inflammasome functions as a negative regulator of tumorigenesis during colitis-associated cancer
- (2010) Irving C. Allen et al. JOURNAL OF EXPERIMENTAL MEDICINE
- NLRC5 Limits the Activation of Inflammatory Pathways
- (2010) S. Benko et al. JOURNAL OF IMMUNOLOGY
- Clinical Features and Outcome of Patients With IRAK-4 and MyD88 Deficiency
- (2010) Capucine Picard et al. MEDICINE
- TLR5 activation induces secretory interleukin-1 receptor antagonist (sIL-1Ra) and reduces inflammasome-associated tissue damage
- (2010) F A Carvalho et al. Mucosal Immunology
- A human gut microbial gene catalogue established by metagenomic sequencing
- (2010) Junjie Qin et al. NATURE
- Overexpression of CD97 in Intestinal Epithelial Cells of Transgenic Mice Attenuates Colitis by Strengthening Adherens Junctions
- (2010) Susann Becker et al. PLoS One
- Immunoregulatory Actions of Epithelial Cell PPAR γ at the Colonic Mucosa of Mice with Experimental Inflammatory Bowel Disease
- (2010) Saroj K. Mohapatra et al. PLoS One
- Bacteria Penetrate the Inner Mucus Layer before Inflammation in the Dextran Sulfate Colitis Model
- (2010) Malin E. V. Johansson et al. PLoS One
- Inflammation-induced tumorigenesis in the colon is regulated by caspase-1 and NLRC4
- (2010) B. Hu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- MyD88 signaling in nonhematopoietic cells protects mice against induced colitis by regulating specific EGF receptor ligands
- (2010) K. Brandl et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Induction of Colonic Regulatory T Cells by Indigenous Clostridium Species
- (2010) K. Atarashi et al. SCIENCE
- Association of NOD1 (CARD4) insertion/deletion polymorphism with susceptibility to IBD: A meta-analysis
- (2010) Wei-Guo Lu WORLD JOURNAL OF GASTROENTEROLOGY
- Potentiation of Epithelial Innate Host Responses by Intercellular Communication
- (2010) Tamas Dolowschiak et al. PLoS Pathogens
- The Microbiota Mediates Pathogen Clearance from the Gut Lumen after Non-Typhoidal Salmonella Diarrhea
- (2010) Kathrin Endt et al. PLoS Pathogens
- Epithelial NF-κB Enhances Transmucosal Fluid Movement by Altering Tight Junction Protein Composition after T Cell Activation
- (2009) Yueming Tang et al. AMERICAN JOURNAL OF PATHOLOGY
- A common role for Atg16L1, Atg5, and Atg7 in small intestinal Paneth cells and Crohn disease
- (2009) Ken Cadwell et al. Autophagy
- Induction of Intestinal Th17 Cells by Segmented Filamentous Bacteria
- (2009) Ivaylo I. Ivanov et al. CELL
- Colitis-Associated Variant of TLR2 Causes Impaired Mucosal Repair Because of TFF3 Deficiency
- (2009) Daniel K. Podolsky et al. GASTROENTEROLOGY
- MHC Class II alleles in ulcerative colitis-associated colorectal cancer
- (2009) M M Garrity-Park et al. GUT
- The Key Role of Segmented Filamentous Bacteria in the Coordinated Maturation of Gut Helper T Cell Responses
- (2009) Valérie Gaboriau-Routhiau et al. IMMUNITY
- TLR2 Mediates Gap Junctional Intercellular Communication through Connexin-43 in Intestinal Epithelial Barrier Injury
- (2009) Birgit Ey et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- STAT3 links IL-22 signaling in intestinal epithelial cells to mucosal wound healing
- (2009) Geethanjali Pickert et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Trans-Presentation of IL-15 by Intestinal Epithelial Cells Drives Development of CD8 IELs
- (2009) L. J. Ma et al. JOURNAL OF IMMUNOLOGY
- Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche
- (2009) Toshiro Sato et al. NATURE
- Sustained in vitro intestinal epithelial culture within a Wnt-dependent stem cell niche
- (2009) Akifumi Ootani et al. NATURE MEDICINE
- Nod2 is required for the regulation of commensal microbiota in the intestine
- (2009) T. Petnicki-Ocwieja et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Differential NF- B pathways induction by Lactobacillus plantarum in the duodenum of healthy humans correlating with immune tolerance
- (2009) P. van Baarlen et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- O-Antigen Delays Lipopolysaccharide Recognition and Impairs Antibacterial Host Defense in Murine Intestinal Epithelial Cells
- (2009) Claudia U. Duerr et al. PLoS Pathogens
- Regional variations in Paneth cell antimicrobial peptide expression along the mouse intestinal tract
- (2008) Jenny Karlsson et al. BMC IMMUNOLOGY
- XBP1 Links ER Stress to Intestinal Inflammation and Confers Genetic Risk for Human Inflammatory Bowel Disease
- (2008) Arthur Kaser et al. CELL
- Toll-Like Receptor Signaling in Small Intestinal Epithelium Promotes B-Cell Recruitment and IgA Production in Lamina Propria
- (2008) Limin Shang et al. GASTROENTEROLOGY
- Intestinal Deletion of Pofut1 in the Mouse Inactivates Notch Signaling and Causes Enterocolitis
- (2008) Sandra Guilmeau et al. GASTROENTEROLOGY
- A key role for autophagy and the autophagy gene Atg16l1 in mouse and human intestinal Paneth cells
- (2008) Ken Cadwell et al. NATURE
- Lymphoid tissue genesis induced by commensals through NOD1 regulates intestinal homeostasis
- (2008) Djahida Bouskra et al. NATURE
- Common variants in the NLRP3 region contribute to Crohn's disease susceptibility
- (2008) Alexandra-Chloé Villani et al. NATURE GENETICS
- TRAM couples endocytosis of Toll-like receptor 4 to the induction of interferon-β
- (2008) Jonathan C Kagan et al. NATURE IMMUNOLOGY
- Paneth cells directly sense gut commensals and maintain homeostasis at the intestinal host-microbial interface
- (2008) S. Vaishnava et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now