Progressive methylation of ageing histones by Dot1 functions as a timer

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A Modified Epigenetics Toolbox to Study Histone Modifications on the Nucleosome Core

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Linking H3K79 trimethylation to Wnt signaling through a novel Dot1-containing complex (DotCom)

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Kinetics of Re-establishing H3K79 Methylation Marks in Global Human Chromatin

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Mitotic bookmarking of genes: a novel dimension to epigenetic control

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Molecular Signals of Epigenetic States

(2010) Roberto Bonasio et al.   SCIENCE

Fast signals and slow marks: the dynamics of histone modifications

(2010) Teresa K. Barth et al.   TRENDS IN BIOCHEMICAL SCIENCES

Timing control in regulatory networks by multisite protein modifications

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In VivoResidue-specific Histone Methylation Dynamics

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Linking Cell Cycle to Histone Modifications: SBF and H2B Monoubiquitination Machinery and Cell-Cycle Regulation of H3K79 Dimethylation

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Recombination-induced tag exchange to track old and new proteins

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Evidence for Gene-Specific Rather Than Transcription Rate–Dependent Histone H3 Exchange in Yeast Coding Regions

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Chemically ubiquitylated histone H2B stimulates hDot1L-mediated intranucleosomal methylation

(2008) Robert K. McGinty et al.   NATURE

The effect of H3K79 dimethylation and H4K20 trimethylation on nucleosome and chromatin structure

(2008) Xu Lu et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Nonprocessive methylation by Dot1 leads to functional redundancy of histone H3K79 methylation states

(2008) Floor Frederiks et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The Histone H3K79 Methyltransferase Dot1L Is Essential for Mammalian Development and Heterochromatin Structure

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