Melatonin influences somatostatin secretion from human pancreaticδ-cells via MT1 and MT2 receptors

A stress response pathway in mice upregulates somatostatin level and transcription in pancreatic delta cells through Gs and β-arrestin 1

(2014) Hong-Mei Wang et al.   DIABETOLOGIA

Melatonin synthesis impairment as a new deleterious outcome of diabetes-derived hyperglycemia

(2014) Fernanda G. Amaral et al.   JOURNAL OF PINEAL RESEARCH

Melatonin MT1and MT2receptors display different molecular pharmacologies only in the G-protein coupled state

(2013) Céline Legros et al.   BRITISH JOURNAL OF PHARMACOLOGY

Autonomous and self-sustained circadian oscillators displayed in human islet cells

(2012) P. Pulimeno et al.   DIABETOLOGIA

Evidence of the receptor-mediated influence of melatonin on pancreatic glucagon secretion via the Gαq protein-coupled and PI3K signaling pathways

(2012) Ina Bähr et al.   JOURNAL OF PINEAL RESEARCH

Melatonin influences insulin secretion primarily via MT1 receptors in rat insulinoma cells (INS-1) and mouse pancreatic islets

(2012) Eckhard Mühlbauer et al.   JOURNAL OF PINEAL RESEARCH

Melatonin inhibits insulin secretion in rat insulinoma β-cells (INS-1) heterologously expressing the human melatonin receptor isoform MT2

(2011) Eckhard Mühlbauer et al.   JOURNAL OF PINEAL RESEARCH

Melatonin stimulates glucagon secretion in vitro and in vivo

(2011) Ina Bähr et al.   JOURNAL OF PINEAL RESEARCH

Electrophysiology of pancreatic β-cells in intact mouse islets of Langerhans

(2011) Patrik Rorsman et al.   PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY

A role for islet somatostatin in mediating sympathetic regulation of glucagon secretion

(2011) Astrid C. Hauge-Evans et al.   Islets

An intrinsic circadian clock of the pancreas is required for normal insulin release and glucose homeostasis in mice

(2010) L. A. Sadacca et al.   DIABETOLOGIA

Pancreatic islet cells: A model for calcium‐dependent peptide release

(2010) Bernat Soria et al.   HFSP Journal

International Union of Basic and Clinical Pharmacology. LXXV. Nomenclature, Classification, and Pharmacology of G Protein-Coupled Melatonin Receptors

(2010) M. L. Dubocovich et al.   PHARMACOLOGICAL REVIEWS

Exocytotic Properties of Human Pancreatic β-cells

(2009) Matthias Braun et al.   Annals of the New York Academy of Sciences

Somatostatin release, electrical activity, membrane currents and exocytosis in human pancreatic delta cells

(2009) M. Braun et al.   DIABETOLOGIA

Glucose Generates Coincident Insulin and Somatostatin Pulses and Antisynchronous Glucagon Pulses from Human Pancreatic Islets

(2009) Bo Hellman et al.   ENDOCRINOLOGY

Loss of melatonin signalling and its impact on circadian rhythms in mouse organs regulating blood glucose

(2009) Eckhard Mühlbauer et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Clock genes and metabolic disease

(2009) Biliana Marcheva et al.   JOURNAL OF APPLIED PHYSIOLOGY

Islet G protein-coupled receptors as potential targets for treatment of type 2 diabetes

(2009) Bo Ahrén   NATURE REVIEWS DRUG DISCOVERY

Somatostatin Secreted by Islet  -Cells Fulfills Multiple Roles as a Paracrine Regulator of Islet Function

(2008) A. C. Hauge-Evans et al.   DIABETES

Somatostatin Actions via Somatostatin Receptors on the Ocular Surface Are Modulated by Inflammatory Processes

(2008) Ivonne Minsel et al.   ENDOCRINOLOGY

Pancreas islets in metabolic signaling - focus on the beta-cell

(2008) Jakob Suckale   Frontiers in Bioscience-Landmark

Function and expression of melatonin receptors on human pancreatic islets

(2008) Reshma D. Ramracheya et al.   JOURNAL OF PINEAL RESEARCH

Involvement of the cGMP pathway in mediating the insulin-inhibitory effect of melatonin in pancreatic β-cells

(2008) Ina Stumpf et al.   JOURNAL OF PINEAL RESEARCH

Modulation of the cGMP signaling pathway by melatonin in pancreaticβ-cells

(2008) Ina Stumpf et al.   JOURNAL OF PINEAL RESEARCH

Common variant in MTNR1B associated with increased risk of type 2 diabetes and impaired early insulin secretion

(2008) Valeriya Lyssenko et al.   NATURE GENETICS

MT1 melatonin receptor internalization underlies melatonin-induced morphologic changes in Chinese hamster ovary cells and these processes are dependent on Gi proteins, MEK 1/2 and microtubule modulation

(2007) C. Dominic Bondi et al.   JOURNAL OF PINEAL RESEARCH