Lis1 controls dynamics of neuronal filopodia and spines to impact synaptogenesis and social behaviour

Patterns and rates of exonic de novo mutations in autism spectrum disorders

(2012) Benjamin M. Neale et al.   NATURE

LIS1-dependent retrograde translocation of excitatory synapses in developing interneuron dendrites

(2012) Izumi Kawabata et al.   Nature Communications

Synaptic changes in the brain of subjects with schizophrenia

(2011) Gábor Faludi et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE

Shank3 mutant mice display autistic-like behaviours and striatal dysfunction

(2011) João Peça et al.   NATURE

Haploinsufficiency of the autism-associated Shank3 gene leads to deficits in synaptic function, social interaction, and social communication

(2011) Ozlem Bozdagi et al.   Molecular Autism

LIS1 and NudE Induce a Persistent Dynein Force-Producing State

(2010) Richard J. McKenney et al.   CELL

Filopodial protrusions induced by glycoprotein M6a exhibit high motility and aids synapse formation

(2010) Marcela A. Brocco et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Thinned-skull cranial window technique for long-term imaging of the cortex in live mice

(2010) Guang Yang et al.   Nature Protocols

Behavioural phenotyping assays for mouse models of autism

(2010) Jill L. Silverman et al.   NATURE REVIEWS NEUROSCIENCE

Key role for gene dosage and synaptic homeostasis in autism spectrum disorders

(2010) Roberto Toro et al.   TRENDS IN GENETICS

Seizures, enhanced excitation, and increased vesicle number inLis1mutant mice

(2009) Joel S.F. Greenwood et al.   ANNALS OF NEUROLOGY

LIS1-Related Isolated Lissencephaly

(2009) Yoann Saillour et al.   ARCHIVES OF NEUROLOGY

Mutant Pink1 induces mitochondrial dysfunction in a neuronal cell model of Parkinson’s disease by disturbing calcium flux

(2009) Roberta Marongiu et al.   JOURNAL OF NEUROCHEMISTRY

Stably maintained dendritic spines are associated with lifelong memories

(2009) Guang Yang et al.   NATURE

Marble burying reflects a repetitive and perseverative behavior more than novelty-induced anxiety

(2009) Alexia Thomas et al.   PSYCHOPHARMACOLOGY