Novel APP/Aβ mutation K16N produces highly toxic heteromeric Aβ oligomers

ADAM10 is the physiologically relevant, constitutive α-secretase of the amyloid precursor protein in primary neurons

(2010) Peer-Hendrik Kuhn et al.   EMBO JOURNAL

Neurotoxicity of Alzheimer's disease Aβ peptides is induced by small changes in the Aβ42 to Aβ40 ratio

(2010) Inna Kuperstein et al.   EMBO JOURNAL

Subcellular localization and dimerization of APLP1 are strikingly different from APP and APLP2

(2009) D. Kaden et al.   JOURNAL OF CELL SCIENCE

Role of Amyloid-  Glycine 33 in Oligomerization, Toxicity, and Neuronal Plasticity

(2009) A. Harmeier et al.   JOURNAL OF NEUROSCIENCE

A Recessive Mutation in the APP Gene with Dominant-Negative Effect on Amyloidogenesis

(2009) G. Di Fede et al.   SCIENCE

Genetic screening of Alzheimer's disease genes in Iberian and African samples yields novel mutations in presenilins and APP

(2008) Rita Joao Guerreiro et al.   NEUROBIOLOGY OF AGING

Aggregation and catabolism of disease-associated intra-Aβ mutations: reduced proteolysis of AβA21G by neprilysin

(2008) Vicki Betts et al.   NEUROBIOLOGY OF DISEASE