MicroRNA therapeutics in cardiovascular medicine

Deregulation of microRNA-503 Contributes to Diabetes Mellitus–Induced Impairment of Endothelial Function and Reparative Angiogenesis After Limb Ischemia

(2011) Andrea Caporali et al.   CIRCULATION

MicroRNA-24 Regulates Vascularity After Myocardial Infarction

(2011) Jan Fiedler et al.   CIRCULATION

Therapeutic Inhibition of miR-208a Improves Cardiac Function and Survival During Heart Failure

(2011) Rusty L. Montgomery et al.   CIRCULATION

miR-15 Family Regulates Postnatal Mitotic Arrest of Cardiomyocytes

(2011) Enzo R. Porrello et al.   CIRCULATION RESEARCH

MicroRNA-29 in Aortic Dilation: Implications for Aneurysm Formation

(2011) Reinier A. Boon et al.   CIRCULATION RESEARCH

MicroRNA-23 Restricts Cardiac Valve Formation by Inhibiting Has2 and Extracellular Hyaluronic Acid Production

(2011) Anne Karine Lagendijk et al.   CIRCULATION RESEARCH

Biogenesis and Regulation of Cardiovascular MicroRNAs

(2011) Johann Bauersachs et al.   CIRCULATION RESEARCH

The Art of MicroRNA Research

(2011) Eva van Rooij   CIRCULATION RESEARCH

A Slit/miR-218/Robo regulatory loop is required during heart tube formation in zebrafish

(2011) Jason E. Fish et al.   DEVELOPMENT

MicroRNA-200b Regulates Vascular Endothelial Growth Factor-Mediated Alterations in Diabetic Retinopathy

(2011) K. McArthur et al.   DIABETES

Gene therapy for ischemic heart disease

(2011) Rabea Hinkel et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

Comparison of different miR-21 inhibitor chemistries in a cardiac disease model

(2011) Thomas Thum et al.   JOURNAL OF CLINICAL INVESTIGATION

Diagnostic and prognostic impact of six circulating microRNAs in acute coronary syndrome

(2011) Christian Widera et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Smad3-Mediated Upregulation of miR-21 Promotes Renal Fibrosis

(2011) X. Zhong et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Inhibition of miR-33a/b in non-human primates raises plasma HDL and lowers VLDL triglycerides

(2011) Katey J. Rayner et al.   NATURE

Silencing of microRNA families by seed-targeting tiny LNAs

(2011) Susanna Obad et al.   NATURE GENETICS

MicroRNA-519c Suppresses Hypoxia-Inducible Factor-1α Expression and Tumor Angiogenesis

(2010) Shih-Ting Cha et al.   CANCER RESEARCH

MicroRNA-328 Contributes to Adverse Electrical Remodeling in Atrial Fibrillation

(2010) Yanjie Lu et al.   CIRCULATION

Circulating MicroRNAs in Patients With Coronary Artery Disease

(2010) Stephan Fichtlscherer et al.   CIRCULATION RESEARCH

Plasma MicroRNA Profiling Reveals Loss of Endothelial MiR-126 and Other MicroRNAs in Type 2 Diabetes

(2010) Anna Zampetaki et al.   CIRCULATION RESEARCH

Thioredoxin 1 Negatively Regulates Angiotensin II–Induced Cardiac Hypertrophy Through Upregulation of miR-98/let-7

(2010) Yanfei Yang et al.   CIRCULATION RESEARCH

Circulating MicroRNAs as Biomarkers and Potential Paracrine Mediators of Cardiovascular Disease

(2010) Shashi K. Gupta et al.   Circulation-Cardiovascular Genetics

MicroRNAs and Cardiac Conduction

(2010) M.V.G. Latronico et al.   CURRENT DRUG TARGETS

MicroRNAs in Arterial Remodelling, Inflammation and Atherosclerosis

(2010) C. Weber et al.   CURRENT DRUG TARGETS

MicroRNAs in lipid metabolism

(2010) Carlos Fernández-Hernando et al.   CURRENT OPINION IN LIPIDOLOGY

Stress-dependent cardiac remodeling occurs in the absence of microRNA-21 in mice

(2010) David M. Patrick et al.   JOURNAL OF CLINICAL INVESTIGATION

miR-21 mediates fibrogenic activation of pulmonary fibroblasts and lung fibrosis

(2010) Gang Liu et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The next step in gene delivery: Molecular engineering of adeno-associated virus serotypes

(2010) Jinhui Wang et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

MicroRNA-199b targets the nuclear kinase Dyrk1a in an auto-amplification loop promoting calcineurin/NFAT signalling

(2010) Paula A. da Costa Martins et al.   NATURE CELL BIOLOGY

miR-33 links SREBP-2 induction to repression of sterol transporters

(2010) T. J. Marquart et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MicroRNA-33 encoded by an intron of sterol regulatory element-binding protein 2 (Srebp2) regulates HDL in vivo

(2010) T. Horie et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MicroRNA-33 and the SREBP Host Genes Cooperate to Control Cholesterol Homeostasis

(2010) S. H. Najafi-Shoushtari et al.   SCIENCE

MiR-33 Contributes to the Regulation of Cholesterol Homeostasis

(2010) K. J. Rayner et al.   SCIENCE

MicroRNA expression in response to murine myocardial infarction: miR-21 regulates fibroblast metalloprotease-2 via phosphatase and tensin homologue

(2009) Sashwati Roy et al.   CARDIOVASCULAR RESEARCH

The knockout of miR-143 and -145 alters smooth muscle cell maintenance and vascular homeostasis in mice: correlates with human disease

(2009) L Elia et al.   CELL DEATH AND DIFFERENTIATION

MicroRNA-320 Is Involved in the Regulation of Cardiac Ischemia/Reperfusion Injury by Targeting Heat-Shock Protein 20

(2009) Xiao-Ping Ren et al.   CIRCULATION

MicroRNA-145, a Novel Smooth Muscle Cell Phenotypic Marker and Modulator, Controls Vascular Neointimal Lesion Formation

(2009) Yunhui Cheng et al.   CIRCULATION RESEARCH

A Necessary Role of miR-221 and miR-222 in Vascular Smooth Muscle Cell Proliferation and Neointimal Hyperplasia

(2009) Xiaojun Liu et al.   CIRCULATION RESEARCH

Inflammation as a therapeutic target in heart failure? A scientific statement from the Translational Research Committee of the Heart Failure Association of the European Society of Cardiology

(2009) Stephane Heymans et al.   EUROPEAN JOURNAL OF HEART FAILURE

MicroRNAs miR-143 and miR-145 modulate cytoskeletal dynamics and responsiveness of smooth muscle cells to injury

(2009) M. Xin et al.   GENES & DEVELOPMENT

Acquisition of the contractile phenotype by murine arterial smooth muscle cells depends on the Mir143/145 gene cluster

(2009) Thomas Boettger et al.   JOURNAL OF CLINICAL INVESTIGATION

MicroRNA-92a Controls Angiogenesis and Functional Recovery of Ischemic Tissues in Mice

(2009) A. Bonauer et al.   SCIENCE

Therapeutic Silencing of MicroRNA-122 in Primates with Chronic Hepatitis C Virus Infection

(2009) R. E. Lanford et al.   SCIENCE

MicroRNAs: novel regulators in cardiac development and disease

(2008) T. Thum et al.   CARDIOVASCULAR RESEARCH

The Endothelial-Specific MicroRNA miR-126 Governs Vascular Integrity and Angiogenesis

(2008) Shusheng Wang et al.   DEVELOPMENTAL CELL

Adeno-Associated Virus (AAV) Serotype 9 Provides Global Cardiac Gene Transfer Superior to AAV1, AAV6, AAV7, and AAV8 in the Mouse and Rat

(2008) Lawrence T. Bish et al.   HUMAN GENE THERAPY

Antagomir-mediated silencing of endothelial cell specific microRNA-126 impairs ischemia-induced angiogenesis

(2008) Coen van Solingen et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

MicroRNA-21 contributes to myocardial disease by stimulating MAP kinase signalling in fibroblasts

(2008) Thomas Thum et al.   NATURE

SMAD proteins control DROSHA-mediated microRNA maturation

(2008) Brandi N. Davis et al.   NATURE

LNA-mediated microRNA silencing in non-human primates

(2008) Joacim Elmén et al.   NATURE

Cardiac Plasticity

(2008) Joseph A. Hill et al.   NEW ENGLAND JOURNAL OF MEDICINE

Detection of microRNA Expression in Human Peripheral Blood Microvesicles

(2008) Melissa Piper Hunter et al.   PLoS One

Dysregulation of microRNAs after myocardial infarction reveals a role of miR-29 in cardiac fibrosis

(2008) E. van Rooij et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA