A matrix metalloprotease-PAR1 system regulates vascular integrity, systemic inflammation and death in sepsis

Sepsis in General Surgery

(2010) Laura J. Moore   ARCHIVES OF SURGERY

Inflammation and coagulation

(2010) Marcel Levi et al.   CRITICAL CARE MEDICINE

Development of Monocytes, Macrophages, and Dendritic Cells

(2010) F. Geissmann et al.   SCIENCE

Matrix metalloproteinases: What do they not do? New substrates and biological roles identified by murine models and proteomics

(2009) David Rodríguez et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Protective mechanisms of activated protein C in severe inflammatory disorders

(2009) Arne P Neyrinck et al.   BRITISH JOURNAL OF PHARMACOLOGY

Platelet Matrix Metalloprotease-1 Mediates Thrombogenesis by Activating PAR1 at a Cryptic Ligand Site

(2009) Vishal Trivedi et al.   CELL

Matrix Metalloproteinases as Drug Targets in Infections Caused by Gram-Negative Bacteria and in Septic Shock

(2009) I. Vanlaere et al.   CLINICAL MICROBIOLOGY REVIEWS

Surviving Sepsis Campaign: International guidelines for management of severe sepsis and septic shock: 2008

(2009) R Phillip Dellinger et al.   CRITICAL CARE MEDICINE

Enhanced Endothelial Cell Senescence by Lithium-induced Matrix Metalloproteinase-1 Expression

(2009) Ian T. Struewing et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Animal models of sepsis and sepsis-induced kidney injury

(2009) Kent Doi et al.   JOURNAL OF CLINICAL INVESTIGATION

A prospective, multicenter derivation of a biomarker panel to assess risk of organ dysfunction, shock, and death in emergency department patients with suspected sepsis

(2008) Nathan I. Shapiro et al.   CRITICAL CARE MEDICINE

Host–pathogen interactions in sepsis

(2007) Tom van der Poll et al.   LANCET INFECTIOUS DISEASES