The rough endoplasmatic reticulum is a central nucleation site of siRNA-mediated RNA silencing

Cytoplasmic Arabidopsis AGO7 accumulates in membrane-associated siRNA bodies and is required for ta-siRNA biogenesis

(2012) Virginie Jouannet et al.   EMBO JOURNAL

Isoprenoid biosynthesis is required for miRNA function and affects membrane association of ARGONAUTE 1 in Arabidopsis

(2012) P. Brodersen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Alternative RISC assembly: Binding and repression of microRNA-mRNA duplexes by human Ago proteins

(2012) M. M. Janas et al.   RNA

Hierarchical regulation of mRNA partitioning between the cytoplasm and the endoplasmic reticulum of mammalian cells

(2011) Qiang Chen et al.   MOLECULAR BIOLOGY OF THE CELL

siRNA Repositioning for Guide Strand Selection by Human Dicer Complexes

(2011) Cameron L. Noland et al.   MOLECULAR CELL

Structure of C3PO and mechanism of human RISC activation

(2011) Xuecheng Ye et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Human Ago2 Is Required for Efficient MicroRNA 122 Regulation of Hepatitis C Virus RNA Accumulation and Translation

(2010) J. A. Wilson et al.   JOURNAL OF VIROLOGY

HSP90 Protein Stabilizes Unloaded Argonaute Complexes and Microscopic P-bodies in Human Cells

(2010) Michael Johnston et al.   MOLECULAR BIOLOGY OF THE CELL

Hsc70/Hsp90 Chaperone Machinery Mediates ATP-Dependent RISC Loading of Small RNA Duplexes

(2010) Shintaro Iwasaki et al.   MOLECULAR CELL

In Vitro Assembly of Plant RNA-Induced Silencing Complexes Facilitated by Molecular Chaperone HSP90

(2010) Taichiro Iki et al.   MOLECULAR CELL

Small RNA sorting: matchmaking for Argonautes

(2010) Benjamin Czech et al.   NATURE REVIEWS GENETICS

A direct role for Hsp90 in pre-RISC formation in Drosophila

(2010) Tomohiro Miyoshi et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Quantitative evaluation of siRNA delivery in vivo

(2010) Y. Pei et al.   RNA

Making RISC

(2010) Tomoko Kawamata et al.   TRENDS IN BIOCHEMICAL SCIENCES

Control of RNA silencing and localization by endolysosomes

(2010) Derrick Gibbings et al.   TRENDS IN CELL BIOLOGY

Characterization of the TRBP domain required for Dicer interaction and function in RNA interference

(2009) Sylvanne M Daniels et al.   BMC MOLECULAR BIOLOGY

Origins and Mechanisms of miRNAs and siRNAs

(2009) Richard W. Carthew et al.   CELL

Hsp90 Regulates the Function of Argonaute 2 and Its Recruitment to Stress Granules and P-Bodies

(2009) Justin M. Pare et al.   MOLECULAR BIOLOGY OF THE CELL

A Novel Mechanism Is Involved in Cationic Lipid-Mediated Functional siRNA Delivery

(2009) James J. Lu et al.   MOLECULAR PHARMACEUTICS

Multivesicular bodies associate with components of miRNA effector complexes and modulate miRNA activity

(2009) Derrick J. Gibbings et al.   NATURE CELL BIOLOGY

ATP-dependent human RISC assembly pathways

(2009) Mayuko Yoda et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Processing bodies are not required for mammalian nonsense-mediated mRNA decay

(2009) L. Stalder et al.   RNA

C3PO, an Endoribonuclease That Promotes RNAi by Facilitating RISC Activation

(2009) Y. Liu et al.   SCIENCE

Phosphorylation of Argonaute 2 at serine-387 facilitates its localization to processing bodies

(2008) Yan Zeng et al.   BIOCHEMICAL JOURNAL

Localization of Double-stranded Small Interfering RNA to Cytoplasmic Processing Bodies Is Ago2 Dependent and Results in Up-Regulation of GW182 and Argonaute-2

(2008) Aarti Jagannath et al.   MOLECULAR BIOLOGY OF THE CELL

Essential role of Pin1 in the regulation of TRF1 stability and telomere maintenance

(2008) Tae Ho Lee et al.   NATURE CELL BIOLOGY

Fluorescence correlation spectroscopy and fluorescence cross-correlation spectroscopy reveal the cytoplasmic origination of loaded nuclear RISC in vivo in human cells

(2008) Thomas Ohrt et al.   NUCLEIC ACIDS RESEARCH

In vitro reconstitution of the human RISC-loading complex

(2008) I. J. MacRae et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A multifunctional human Argonaute2-specific monoclonal antibody

(2008) S. Rudel et al.   RNA

Message on the web: mRNA and ER co-trafficking

(2008) Jeffrey E. Gerst   TRENDS IN CELL BIOLOGY