The active ClpP protease fromM. tuberculosisis a complex composed of a heptameric ClpP1 and a ClpP2 ring

The Natural Product Cyclomarin Kills Mycobacterium Tuberculosis by Targeting the ClpC1 Subunit of the Caseinolytic Protease

(2011) Esther K. Schmitt et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Assembly and proteolytic processing of mycobacterial ClpP1 and ClpP2

(2011) Nadia Benaroudj et al.   BMC BIOCHEMISTRY

Activators of Cylindrical Proteases as Antimicrobials: Identification and Development of Small Molecule Activators of ClpP Protease

(2011) Elisa Leung et al.   CHEMISTRY & BIOLOGY

Validation of the Essential ClpP Protease in Mycobacterium tuberculosis as a Novel Drug Target

(2011) J. Ollinger et al.   JOURNAL OF BACTERIOLOGY

Control of Substrate Gating and Translocation into ClpP by Channel Residues and ClpX Binding

(2010) Mary E. Lee et al.   JOURNAL OF MOLECULAR BIOLOGY

Structures of ClpP in complex with acyldepsipeptide antibiotics reveal its activation mechanism

(2010) Byung-Gil Lee et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Characterization of a Clp Protease Gene Regulator and the Reaeration Response in Mycobacterium tuberculosis

(2010) Ashley M. Sherrid et al.   PLoS One

Controlled destruction: AAA+ ATPases in protein degradation from bacteria to eukaryotes

(2009) Frank Striebel et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

The antibiotic ADEP reprogrammes ClpP, switching it from a regulated to an uncontrolled protease

(2009) Janine Kirstein et al.   EMBO Molecular Medicine

Structure and Function of a Novel Type of ATP-dependent Clp Protease

(2009) Fredrik I. Andersson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

HslVU ATP-dependent Protease Utilizes Maximally Six among Twelve Threonine Active Sites during Proteolysis

(2009) Jung Wook Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

RseA, the SigE specific anti-sigma factor ofMycobacterium tuberculosis, is inactivated by phosphorylation-dependent ClpC1P2 proteolysis

(2009) Subhasis Barik et al.   MOLECULAR MICROBIOLOGY

Clp chaperone–proteases: structure and function

(2009) Wolfgang Kress et al.   RESEARCH IN MICROBIOLOGY

Mechanism of Gate Opening in the 20S Proteasome by the Proteasomal ATPases

(2008) Julius Rabl et al.   MOLECULAR CELL