L1CAM regulates DNA damage checkpoint response of glioblastoma stem cells through NBS1

Potential therapeutic implications of cancer stem cells in glioblastoma

(2010) Lin Cheng et al.   BIOCHEMICAL PHARMACOLOGY

Therapeutic Antibodies to Human L1CAM: Functional Characterization and Application in a Mouse Model for Ovarian Carcinoma

(2010) S. Wolterink et al.   CANCER RESEARCH

The hypoxic microenvironment maintains glioblastoma stem cells and promotes reprogramming towards a cancer stem cell phenotype

(2010) John M. Heddleston et al.   CELL CYCLE

Myc Is Required for Activation of the ATM-Dependent Checkpoints in Response to DNA Damage

(2010) Lina Guerra et al.   PLoS One

L1 cell adhesion molecules as regulators of tumor cell invasiveness

(2010) Priscila F. Siesser et al.   Cell Adhesion & Migration

Nuclear translocation and signalling of L1-CAM in human carcinoma cells requires ADAM10 and presenilin/γ-secretase activity

(2009) Svenja Riedle et al.   BIOCHEMICAL JOURNAL

Hypoxia-Inducible Factors Regulate Tumorigenic Capacity of Glioma Stem Cells

(2009) Zhizhong Li et al.   CANCER CELL

Enhanced MDR1 Expression and Chemoresistance of Cancer Stem Cells Derived from Glioblastoma

(2009) Eiichi Nakai et al.   CANCER INVESTIGATION

L1 cell adhesion molecule (L1CAM) in invasive tumors

(2009) Shani Raveh et al.   CANCER LETTERS

Up-regulation of L1CAM in Pancreatic Duct Cells Is Transforming Growth Factor  1- and Slug-Dependent: Role in Malignant Transformation of Pancreatic Cancer

(2009) C. Geismann et al.   CANCER RESEARCH

Human Glioblastoma-Derived Cancer Stem Cells: Establishment of Invasive Glioma Models and Treatment with Oncolytic Herpes Simplex Virus Vectors

(2009) H. Wakimoto et al.   CANCER RESEARCH

Glioma Tumor Stem-Like Cells Promote Tumor Angiogenesis and Vasculogenesis via Vascular Endothelial Growth Factor and Stromal-Derived Factor 1

(2009) C. Folkins et al.   CANCER RESEARCH

Nbs1 Flexibly Tethers Ctp1 and Mre11-Rad50 to Coordinate DNA Double-Strand Break Processing and Repair

(2009) R. Scott Williams et al.   CELL

Kinases that control the cell cycle in response to DNA damage: Chk1, Chk2, and MK2

(2009) H Christian Reinhardt et al.   CURRENT OPINION IN CELL BIOLOGY

The soluble form of the cancer-associated L1 cell adhesion molecule is a pro-angiogenic factor

(2009) Alexandra Friedli et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Ionizing Radiation Shifts the PAI-1/ID-1 Balance and Activates Notch Signaling in Endothelial Cells

(2009) Marion Scharpfenecker et al.   INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial

(2009) Roger Stupp et al.   LANCET ONCOLOGY

DNA Repair and Resistance of Gliomas to Chemotherapy and Radiotherapy

(2009) G. Frosina   MOLECULAR CANCER RESEARCH

Roles for NBS1 in Alternative Nonhomologous End-Joining of V(D)J Recombination Intermediates

(2009) Ludovic Deriano et al.   MOLECULAR CELL

Association of reactive oxygen species levels and radioresistance in cancer stem cells

(2009) Maximilian Diehn et al.   NATURE

Tumour-initiating cells: challenges and opportunities for anticancer drug discovery

(2009) Bin-Bing S. Zhou et al.   NATURE REVIEWS DRUG DISCOVERY

Targeting Cancer Stem Cells through L1CAM Suppresses Glioma Growth

(2008) S. Bao et al.   CANCER RESEARCH

DNA damage-inducing agents elicit γ-secretase activation mediated by oxidative stress

(2008) S M Jin et al.   CELL DEATH AND DIFFERENTIATION

L1-CAM in cancerous tissues

(2008) Nancy Gavert et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

Malignant Gliomas in Adults

(2008) Patrick Y. Wen et al.   NEW ENGLAND JOURNAL OF MEDICINE