Integrin adhesion and force coupling are independently regulated by localized PtdIns(4,5)2synthesis

Kindlin-2 regulates podocyte adhesion and fibronectin matrix deposition through interactions with phosphoinositides and integrins

(2011) H. Qu et al.   JOURNAL OF CELL SCIENCE

Conformational Control of Integrin-Subtype Selectivity in isoDGR Peptide Motifs: A Biological Switch

(2010) Andreas O. Frank et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Transmembrane Signaling Proteoglycans

(2010) John R. Couchman   Annual Review of Cell and Developmental Biology

Structure of a double ubiquitin-like domain in the talin head: a role in integrin activation

(2010) Benjamin T Goult et al.   EMBO JOURNAL

Integrin-Induced PIP5K1C Kinase Polarization Regulates Neutrophil Polarization, Directionality, and In Vivo Infiltration

(2010) Wenwen Xu et al.   IMMUNITY

Activation of Vinculin Induced by Cholinergic Stimulation Regulates Contraction of Tracheal Smooth Muscle Tissue

(2010) Youliang Huang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Central Region of Talin Has a Unique Fold That Binds Vinculin and Actin

(2010) Alexandre R. Gingras et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Type I PIPK-α regulates directed cell migration by modulating Rac1 plasma membrane targeting and activation

(2010) Wei-Ting Chao et al.   JOURNAL OF CELL BIOLOGY

PIPKI 90 Negatively Regulates LFA-1-Mediated Adhesion and Activation in Antigen-Induced CD4+ T Cells

(2010) S. A. Wernimont et al.   JOURNAL OF IMMUNOLOGY

Integrin and glycocalyx mediated contributions to cell adhesion identified by single cell force spectroscopy

(2010) D Boettiger et al.   JOURNAL OF PHYSICS-CONDENSED MATTER

The Structure of the Talin/Integrin Complex at a Lipid Bilayer: An NMR and MD Simulation Study

(2010) Antreas C. Kalli et al.   STRUCTURE

Two novel phosphatidylinositol-4-phosphate 5-kinase type Iγ splice variants expressed in human cells display distinctive cellular targeting

(2009) Nicholas J. Schill et al.   BIOCHEMICAL JOURNAL

Role of Focal Adhesions and Mechanical Stresses in the Formation and Progression of the Lamellum Interface

(2009) Tom Shemesh et al.   BIOPHYSICAL JOURNAL

The structure of an integrin/talin complex reveals the basis of inside-out signal transduction

(2009) Nicholas J Anthis et al.   EMBO JOURNAL

Genetic and cell biological analysis of integrin outside-in signaling

(2009) K. R. Legate et al.   GENES & DEVELOPMENT

The Structure of an Interdomain Complex That Regulates Talin Activity

(2009) Benjamin T. Goult et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Essential and unique roles of PIP5K-γ and -α in Fcγ receptor-mediated phagocytosis

(2009) Yuntao S. Mao et al.   JOURNAL OF CELL BIOLOGY

New PI(4,5)P2- and membrane proximal integrin–binding motifs in the talin head control β3-integrin clustering

(2009) Frédéric Saltel et al.   JOURNAL OF CELL BIOLOGY

Demonstration of catch bonds between an integrin and its ligand

(2009) Fang Kong et al.   JOURNAL OF CELL BIOLOGY

Mechanisms that regulate adaptor binding to  -integrin cytoplasmic tails

(2009) K. R. Legate et al.   JOURNAL OF CELL SCIENCE

The  - and  -isoforms of type I PIP5K regulate distinct stages of Ca2+ signaling in mast cells

(2009) L. Vasudevan et al.   JOURNAL OF CELL SCIENCE

Clustering of  5 1 integrins determines adhesion strength whereas  v 3 and talin enable mechanotransduction

(2009) P. Roca-Cusachs et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Tail of Integrins, Talin, and Kindlins

(2009) M. Moser et al.   SCIENCE

Mechanically Activated Integrin Switch Controls  5 1 Function

(2009) J. C. Friedland et al.   SCIENCE

Multi-level molecular clutches in motile cell processes

(2009) Grégory Giannone et al.   TRENDS IN CELL BIOLOGY

The oligomeric status of syndecan-4 regulates syndecan-4 interaction with α-actinin

(2008) Youngsil Choi et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

Kindlin-2 controls bidirectional signaling of integrins

(2008) E. Montanez et al.   GENES & DEVELOPMENT

Lipid Binding to the Tail Domain of Vinculin

(2008) Sean M. Palmer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Traction stress in focal adhesions correlates biphasically with actin retrograde flow speed

(2008) Margaret L. Gardel et al.   JOURNAL OF CELL BIOLOGY

Structural Basis for the Autoinhibition of Talin in Regulating Integrin Activation

(2008) Esen Goksoy et al.   MOLECULAR CELL

Talin depletion reveals independence of initial cell spreading from integrin activation and traction

(2008) Xian Zhang et al.   NATURE CELL BIOLOGY

Comparative Dynamics of Retrograde Actin Flow and Focal Adhesions: Formation of Nascent Adhesions Triggers Transition from Fast to Slow Flow

(2008) Antonina Y. Alexandrova et al.   PLoS One

The PTB domain of tensin: NMR solution structure and phosphoinositides binding studies

(2007) Marilisa Leone et al.   BIOPOLYMERS